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KRT10 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol KRT10
Entrez Gene ID 3858
Full Name keratin 10
Synonyms BCIE,BIE,CK10,EHK,K10,KPP
General protein information
Preferred Names

keratin 10

Names

keratin, type I cytoskeletal 10
CK-10
cytokeratin 10
keratin 10, type I

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

17

17q21.2

Summary This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008].
Disorder MIM:

148080

Disorder Html: Epidermolytic hyperkeratosis, 113800 (3); Ichthyosis, cyclic, with

mRNA and Protein(s)

mRNA Protein Name
NM_000421.3 NP_000412.3 keratin, type I cytoskeletal 10
XM_005257343.3 XP_005257400.1 keratin, type I cytoskeletal 10 isoform X1



Related articles in PubMed

Extensive Post-zygotic Mosaicism of KRT1 or KRT10 Mutation Mimicking Classical Epider-molytic Ichthyosis.
Severino-Freire M, Jonca N, Pichery M, Tournier E, Chassaing N, Mazereeuw-Hautier J
Acta dermato-venereologica97(3)387-388(2017 03)

S159P mutation of keratin 10 gene causes severe form of epidermolytic hyperkeratosis.
Chen PJ, Li CX, Wen J, Peng YS, Zeng K, Zhang SQ, Tian X, Zhang XB
Journal of the European Academy of Dermatology and Venereology : JEADV30(10)e102-e104(2016 Oct)

Expanding the Clinical and Genetic Spectrum of KRT1, KRT2 and KRT10 Mutations in Keratinopathic Ichthyosis.
Hotz A, Oji V, Bourrat E, Jonca N, Mazereeuw-Hautier J, Betz RC, Blume-Peytavi U, Stieler K, Morice-Picard F, Schönbuchner I, Markus S, Schlipf N, Fischer J
Acta dermato-venereologica96(4)473-8(2016 May)

Intrafamilial phenotypic heterogeneity of epidermolytic ichthyosis associated with a new missense mutation in keratin 10.
Abdul-Wahab A, Takeichi T, Liu L, Stephens C, Akiyama M, McGrath JA
Clinical and experimental dermatology41(3)290-3(2016 Apr)

Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly.
Bray DJ, Walsh TR, Noro MG, Notman R
PloS one10(7)e0132706(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis.
Title: Extensive Post-zygotic Mosaicism of KRT1 or KRT10 Mutation Mimicking Classical Epider-molytic Ichthyosis.

Mutations in the highly conserved helix initiation motif of K10 were associated with mild or severe form of epidermolytic ichthyosis
Title: S159P mutation of keratin 10 gene causes severe form of epidermolytic hyperkeratosis.

KRT10 gene mutation was present in all of the affected individuals, but absent in the five unaffected and 100 ethnically-matched healthy controls.
Title: Ichthyosis hystrix Lambert type and Curth-Macklin type are a single entity with affected (KRT1 mutation) or unaffected (KRT10 mutation) palms and soles?

Report genetic/clinical spectrum of KRT10 mutations in keratinopathic ichthyosis.
Title: Expanding the Clinical and Genetic Spectrum of KRT1, KRT2 and KRT10 Mutations in Keratinopathic Ichthyosis.

We present an autosomal dominant pedigree with epidermolytic ichthyosis resulting from a new heterozygous missense mutation in keratin 10.
Title: Intrafamilial phenotypic heterogeneity of epidermolytic ichthyosis associated with a new missense mutation in keratin 10.

The following KRT10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRT10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu19931 NM_000421.3
Latest version!
Homo sapiens keratin 10 (KRT10), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $307.30
$439.00
OHu50364 XM_005257343.3
Latest version!
Homo sapiens keratin 10 (KRT10), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $307.30
$439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19931
Clone ID Related Accession (Same CDS sequence) NM_000421.3
Accession Version NM_000421.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1755bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-04
Organism Homo sapiens(Human)
Product keratin, type I cytoskeletal 10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CU455823.1, BC034697.1 and M77663.1. This sequence is a reference standard in the RefSeqGene project. On Aug 9, 2008 this sequence version replaced NM_000421.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC034697.1, ERR279840.7708.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGTCTGTTC GATACAGCTC AAGCAAGCAC TACTCTTCCT CCCGCAGTGG AGGAGGAGGA 
GGAGGAGGAG GATGTGGAGG AGGAGGAGGA GTGTCATCCC TAAGAATTTC TAGCAGCAAA
GGCTCCCTTG GTGGAGGATT TAGCTCAGGG GGGTTCAGTG GTGGCTCTTT TAGCCGTGGG
AGCTCTGGTG GGGGCTGCTT TGGGGGCTCA TCAGGTGGCT ATGGAGGATT AGGAGGTTTT
GGTGGAGGTA GCTTTCGTGG AAGCTATGGA AGTAGCAGCT TTGGTGGGAG TTATGGAGGC
AGCTTTGGAG GGGGCAGTTT CGGAGGTGGC AGCTTTGGTG GGGGCAGCTT TGGTGGAGGC
GGCTTTGGTG GAGGCGGCTT TGGAGGAGGC TTTGGTGGTG GATTTGGAGG AGATGGTGGC
CTTCTCTCTG GAAATGAAAA AGTAACCATG CAGAATCTGA ATGACCGCCT GGCTTCCTAC
TTGGACAAAG TTCGGGCTCT GGAAGAATCA AACTATGAGC TGGAAGGCAA AATCAAGGAG
TGGTATGAAA AGCATGGCAA CTCACATCAG GGGGAGCCTC GTGACTACAG CAAATACTAC
AAAACCATCG ATGACCTTAA AAATCAGATT CTCAACCTAA CAACTGATAA TGCCAACATC
CTGCTTCAGA TCGACAATGC CAGGCTGGCA GCTGATGACT TCAGGCTGAA GTATGAGAAT
GAGGTAGCTC TGCGCCAGAG CGTGGAGGCT GACATCAACG GCCTGCGTAG GGTGCTGGAT
GAGCTGACCC TGACCAAGGC TGACCTGGAG ATGCAAATTG AGAGCCTGAC TGAAGAGCTG
GCCTATCTGA AGAAGAACCA CGAGGAGGAA ATGAAAGACC TTCGAAATGT GTCCACTGGT
GATGTGAATG TGGAAATGAA TGCTGCCCCG GGTGTTGATC TGACTCAACT TCTGAATAAC
ATGAGAAGCC AATATGAACA ACTTGCTGAA CAAAACCGCA AAGATGCTGA AGCCTGGTTC
AATGAAAAGA GCAAGGAACT GACTACAGAA ATTGATAATA ACATTGAACA GATATCCAGC
TATAAATCTG AGATTACTGA ATTGAGACGT AATGTACAAG CTCTGGAGAT AGAACTACAG
TCCCAACTGG CCTTGAAACA ATCCCTGGAA GCCTCCTTGG CAGAAACAGA AGGTCGCTAC
TGTGTGCAGC TCTCACAGAT TCAGGCCCAG ATATCCGCTC TGGAAGAACA GTTGCAACAG
ATTCGAGCTG AAACCGAGTG CCAGAATACT GAATACCAAC AACTCCTGGA TATTAAGATC
CGACTGGAGA ATGAAATTCA AACCTACCGC AGCCTGCTAG AAGGAGAGGG AAGTTCCGGA
GGCGGCGGAC GCGGCGGCGG AAGTTTCGGC GGCGGCTACG GCGGCGGAAG CTCCGGCGGC
GGAAGCTCCG GCGGCGGCCA CGGCGGCGGC CACGGCGGCA GTTCCGGCGG CGGCTACGGA
GGCGGAAGCT CCGGCGGCGG AAGCTCCGGC GGCGGCTACG GGGGCGGAAG CTCCAGCGGC
GGCCACGGCG GCAGTTCCAG CGGCGGCTAC GGTGGTGGCA GTTCCGGCGG CGGCGGCGGC
GGCTACGGGG GCGGCAGCTC CGGCGGCGGC AGCAGCTCCG GCGGCGGATA CGGCGGCGGC
AGCTCCAGCG GAGGCCACAA GTCCTCCTCT TCCGGGTCCG TGGGCGAGTC TTCATCTAAG
GGACCAAGAT ACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000412.3
CDS27..1781
Misc Feature(1)27..461
Misc Feature(2)66..68
Misc Feature(3)72..74
Misc Feature(4)150..152
Misc Feature(5)183..185
Misc Feature(6)192..194
Misc Feature(7)459..1388
Misc Feature(8)462..1394
Misc Feature(9)462..569
Misc Feature(10)534..536
Misc Feature(11)570..632
Misc Feature(12)633..908
Misc Feature(13)909..977
Misc Feature(14)978..1394
Misc Feature(15)1395..1778
Exon (1)1..653
Exon (2)654..736
Exon (3)737..893
Exon (4)894..1055
Exon (5)1056..1181
Exon (6)1182..1399
Exon (7)1400..1774
Exon (8)1775..2140
Translation

Target ORF information:

RefSeq Version NM_000421.3
Organism Homo sapiens(Human)
Definition Homo sapiens keratin 10 (KRT10), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000421.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGTCTGTTC GATACAGCTC AAGCAAGCAC TACTCTTCCT CCCGCAGTGG AGGAGGAGGA 
GGAGGAGGAG GATGTGGAGG AGGAGGAGGA GTGTCATCCC TAAGAATTTC TAGCAGCAAA
GGCTCCCTTG GTGGAGGATT TAGCTCAGGG GGGTTCAGTG GTGGCTCTTT TAGCCGTGGG
AGCTCTGGTG GGGGCTGCTT TGGGGGCTCA TCAGGTGGCT ATGGAGGATT AGGAGGTTTT
GGTGGAGGTA GCTTTCGTGG AAGCTATGGA AGTAGCAGCT TTGGTGGGAG TTATGGAGGC
AGCTTTGGAG GGGGCAGTTT CGGAGGTGGC AGCTTTGGTG GGGGCAGCTT TGGTGGAGGC
GGCTTTGGTG GAGGCGGCTT TGGAGGAGGC TTTGGTGGTG GATTTGGAGG AGATGGTGGC
CTTCTCTCTG GAAATGAAAA AGTAACCATG CAGAATCTGA ATGACCGCCT GGCTTCCTAC
TTGGACAAAG TTCGGGCTCT GGAAGAATCA AACTATGAGC TGGAAGGCAA AATCAAGGAG
TGGTATGAAA AGCATGGCAA CTCACATCAG GGGGAGCCTC GTGACTACAG CAAATACTAC
AAAACCATCG ATGACCTTAA AAATCAGATT CTCAACCTAA CAACTGATAA TGCCAACATC
CTGCTTCAGA TCGACAATGC CAGGCTGGCA GCTGATGACT TCAGGCTGAA GTATGAGAAT
GAGGTAGCTC TGCGCCAGAG CGTGGAGGCT GACATCAACG GCCTGCGTAG GGTGCTGGAT
GAGCTGACCC TGACCAAGGC TGACCTGGAG ATGCAAATTG AGAGCCTGAC TGAAGAGCTG
GCCTATCTGA AGAAGAACCA CGAGGAGGAA ATGAAAGACC TTCGAAATGT GTCCACTGGT
GATGTGAATG TGGAAATGAA TGCTGCCCCG GGTGTTGATC TGACTCAACT TCTGAATAAC
ATGAGAAGCC AATATGAACA ACTTGCTGAA CAAAACCGCA AAGATGCTGA AGCCTGGTTC
AATGAAAAGA GCAAGGAACT GACTACAGAA ATTGATAATA ACATTGAACA GATATCCAGC
TATAAATCTG AGATTACTGA ATTGAGACGT AATGTACAAG CTCTGGAGAT AGAACTACAG
TCCCAACTGG CCTTGAAACA ATCCCTGGAA GCCTCCTTGG CAGAAACAGA AGGTCGCTAC
TGTGTGCAGC TCTCACAGAT TCAGGCCCAG ATATCCGCTC TGGAAGAACA GTTGCAACAG
ATTCGAGCTG AAACCGAGTG CCAGAATACT GAATACCAAC AACTCCTGGA TATTAAGATC
CGACTGGAGA ATGAAATTCA AACCTACCGC AGCCTGCTAG AAGGAGAGGG AAGTTCCGGA
GGCGGCGGAC GCGGCGGCGG AAGTTTCGGC GGCGGCTACG GCGGCGGAAG CTCCGGCGGC
GGAAGCTCCG GCGGCGGCCA CGGCGGCGGC CACGGCGGCA GTTCCGGCGG CGGCTACGGA
GGCGGAAGCT CCGGCGGCGG AAGCTCCGGC GGCGGCTACG GGGGCGGAAG CTCCAGCGGC
GGCCACGGCG GCAGTTCCAG CGGCGGCTAC GGTGGTGGCA GTTCCGGCGG CGGCGGCGGC
GGCTACGGGG GCGGCAGCTC CGGCGGCGGC AGCAGCTCCG GCGGCGGATA CGGCGGCGGC
AGCTCCAGCG GAGGCCACAA GTCCTCCTCT TCCGGGTCCG TGGGCGAGTC TTCATCTAAG
GGACCAAGAT ACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu50364
Clone ID Related Accession (Same CDS sequence) XM_005257343.3
Accession Version XM_005257343.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1875bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product keratin, type I cytoskeletal 10 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005257343.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGTCTGTTC GATACAGCTC AAGCAAGCAC TACTCTTCCT CCCGCAGTGG AGGAGGAGGA 
GGAGGAGGAG GATGTGGAGG AGGAGGAGGA GTGTCATCCC TAAGAATTTC TAGCAGCAAA
GGCTCCCTTG GTGGAGGATT TAGCTCAGGG GGGTTCAGTG GTGGCTCTTT TAGCCGTGGG
AGCTCTGGTG GGGGCTGCTT TGGGGGCTCA TCAGGTGGCT ATGGAGGATT AGGAGGTTTT
GGTGGAGGTA GCTTTCGTGG AAGCTATGGA AGTAGCAGCT TTGGTGGGAG TTATGGAGGC
ATCTTTGGAG GGGGCAGTTT CGGAGGTGGC AGCTTTGGTG GGGGCAGCTT TGGTGGAGGC
GGCTTTGGTG GAGGCGGCTT TGGAGGAGGC TTTGGTGGTG GATTTGGAGG AGATGGTGGC
CTTCTCTCTG GAAATGAAAA AGTAACCATG CAGAATCTGA ATGACCGCCT GGCTTCCTAC
TTGGACAAAG TTCGGGCTCT GGAAGAATCA AACTATGAGC TGGAAGGCAA AATCAAGGAG
TGGTATGAAA AGCATGGCAA CTCACATCAG GGGGAGCCTC GTGACTACAG CAAATACTAC
AAAACCATCG ATGACCTTAA AAATCAGATT CTCAACCTAA CAACTGATAA TGCCAACATC
CTGCTTCAGA TCGACAATGC CAGGCTGGCA GCTGATGACT TCAGGCTGAA GTATGAGAAT
GAGGTAGCTC TGCGCCAGAG CGTGGAGGCT GACATCAACG GCCTGCGTAG GGTGCTGGAT
GAGCTGACCC TGACCAAGGC TGACCTGGAG ATGCAAATTG AGAGCCTGAC TGAAGAGCTG
GCCTATCTGA AGAAGAACCA CGAGGAGGAA ATGAAAGACC TTCGAAATGT GTCCACTGGT
GATGTGAATG TGGAAATGAA TGCTGCCCCG GGTGTTGATC TGACTCAACT TCTGAATAAC
ATGAGAAGCC AATATGAACA ACTTGCTGAA CAAAACCGCA AAGATGCTGA AGCCTGGTTC
AATGAAAAGA GCAAGGAACT GACTACAGAA ATTGATAATA ACATTGAACA GATATCCAGC
TATAAATCTG AGATTACTGA ATTGAGACGT AATGTACAAG CTCTGGAGAT AGAACTACAG
TCCCAACTGG CCTTGAAACA ATCCCTGGAA GCCTCCTTGG CAGAAACAGA AGGTCGCTAC
TGTGTGCAGC TCTCACAGAT TCAGGCCCAG ATATCCGCTC TGGAAGAACA GTTGCAACAG
ATTCGAGCTG AAACCGAGTG CCAGAATACT GAATACCAAC AACTCCTGGA TATTAAGATC
CGACTGGAGA ATGAAATTCA AACCTACCGC AGCCTGCTAG AAGGAGAGGG AAGTTCCGGA
GGCGGCGGAC GCGGCGGCGG AAGTTTCGGC GGCGGCTACG GCGGCGGAAG CTCCGGCGGC
GGAAGCTCCG GCGGCGGCCA CGGCGGCGGC CACGGCGGCA GTTCCGGCGG CGGCTACGGA
GGCGGAAGCT CCGGCGGCGG AAGCTCCGGC GGCGGCTACG GGGGCGGAAG CTCCAGCGGC
GGCCACGGCG GCAGTTCCAG CGGCGGCTAC GGTGGTGGCA GTTCCGGCGG CGGCGGCGGC
GGCTACGGGG GCGGCAGCTC CGGCGGCGGC AGCAGCTCCG GCGGCGGATA CGGCGGCGGC
AGCTCCAGCG GAGGCCACAA GTCCTCCTCT TCCGGGTCCG TGGGCGAGTC TTCATCTAAG
GGACCAAGGT CAGCAGAAAC TAGCTGGGAT ACTAACAAAA CCAGAGTAAT CAAGACAATT
ATTGAAGAGG TGGCGCCCGA CGGTAGAGTT CTTTCATCTA TGGTTGAATC AGAAACCAAG
AAACACTACT ATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005257400.1
CDS37..1911
Misc Feature(1)469..1398
Translation

Target ORF information:

RefSeq Version XM_005257343.3
Organism Homo sapiens(Human)
Definition Homo sapiens keratin 10 (KRT10), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257343.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGTCTGTTC GATACAGCTC AAGCAAGCAC TACTCTTCCT CCCGCAGTGG AGGAGGAGGA 
GGAGGAGGAG GATGTGGAGG AGGAGGAGGA GTGTCATCCC TAAGAATTTC TAGCAGCAAA
GGCTCCCTTG GTGGAGGATT TAGCTCAGGG GGGTTCAGTG GTGGCTCTTT TAGCCGTGGG
AGCTCTGGTG GGGGCTGCTT TGGGGGCTCA TCAGGTGGCT ATGGAGGATT AGGAGGTTTT
GGTGGAGGTA GCTTTCGTGG AAGCTATGGA AGTAGCAGCT TTGGTGGGAG TTATGGAGGC
ATCTTTGGAG GGGGCAGTTT CGGAGGTGGC AGCTTTGGTG GGGGCAGCTT TGGTGGAGGC
GGCTTTGGTG GAGGCGGCTT TGGAGGAGGC TTTGGTGGTG GATTTGGAGG AGATGGTGGC
CTTCTCTCTG GAAATGAAAA AGTAACCATG CAGAATCTGA ATGACCGCCT GGCTTCCTAC
TTGGACAAAG TTCGGGCTCT GGAAGAATCA AACTATGAGC TGGAAGGCAA AATCAAGGAG
TGGTATGAAA AGCATGGCAA CTCACATCAG GGGGAGCCTC GTGACTACAG CAAATACTAC
AAAACCATCG ATGACCTTAA AAATCAGATT CTCAACCTAA CAACTGATAA TGCCAACATC
CTGCTTCAGA TCGACAATGC CAGGCTGGCA GCTGATGACT TCAGGCTGAA GTATGAGAAT
GAGGTAGCTC TGCGCCAGAG CGTGGAGGCT GACATCAACG GCCTGCGTAG GGTGCTGGAT
GAGCTGACCC TGACCAAGGC TGACCTGGAG ATGCAAATTG AGAGCCTGAC TGAAGAGCTG
GCCTATCTGA AGAAGAACCA CGAGGAGGAA ATGAAAGACC TTCGAAATGT GTCCACTGGT
GATGTGAATG TGGAAATGAA TGCTGCCCCG GGTGTTGATC TGACTCAACT TCTGAATAAC
ATGAGAAGCC AATATGAACA ACTTGCTGAA CAAAACCGCA AAGATGCTGA AGCCTGGTTC
AATGAAAAGA GCAAGGAACT GACTACAGAA ATTGATAATA ACATTGAACA GATATCCAGC
TATAAATCTG AGATTACTGA ATTGAGACGT AATGTACAAG CTCTGGAGAT AGAACTACAG
TCCCAACTGG CCTTGAAACA ATCCCTGGAA GCCTCCTTGG CAGAAACAGA AGGTCGCTAC
TGTGTGCAGC TCTCACAGAT TCAGGCCCAG ATATCCGCTC TGGAAGAACA GTTGCAACAG
ATTCGAGCTG AAACCGAGTG CCAGAATACT GAATACCAAC AACTCCTGGA TATTAAGATC
CGACTGGAGA ATGAAATTCA AACCTACCGC AGCCTGCTAG AAGGAGAGGG AAGTTCCGGA
GGCGGCGGAC GCGGCGGCGG AAGTTTCGGC GGCGGCTACG GCGGCGGAAG CTCCGGCGGC
GGAAGCTCCG GCGGCGGCCA CGGCGGCGGC CACGGCGGCA GTTCCGGCGG CGGCTACGGA
GGCGGAAGCT CCGGCGGCGG AAGCTCCGGC GGCGGCTACG GGGGCGGAAG CTCCAGCGGC
GGCCACGGCG GCAGTTCCAG CGGCGGCTAC GGTGGTGGCA GTTCCGGCGG CGGCGGCGGC
GGCTACGGGG GCGGCAGCTC CGGCGGCGGC AGCAGCTCCG GCGGCGGATA CGGCGGCGGC
AGCTCCAGCG GAGGCCACAA GTCCTCCTCT TCCGGGTCCG TGGGCGAGTC TTCATCTAAG
GGACCAAGGT CAGCAGAAAC TAGCTGGGAT ACTAACAAAA CCAGAGTAAT CAAGACAATT
ATTGAAGAGG TGGCGCCCGA CGGTAGAGTT CTTTCATCTA TGGTTGAATC AGAAACCAAG
AAACACTACT ATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Extensive Post-zygotic Mosaicism of KRT1 or KRT10 Mutation Mimicking Classical Epider-molytic Ichthyosis.
Acta dermato-venereologica97(3)387-388(2017 03)
Severino-Freire M,Jonca N,Pichery M,Tournier E,Chassaing N,Mazereeuw-Hautier J


book

S159P mutation of keratin 10 gene causes severe form of epidermolytic hyperkeratosis.
Journal of the European Academy of Dermatology and Venereology : JEADV30(10)e102-e104(2016 Oct)
Chen PJ,Li CX,Wen J,Peng YS,Zeng K,Zhang SQ,Tian X,Zhang XB


book

Expanding the Clinical and Genetic Spectrum of KRT1, KRT2 and KRT10 Mutations in Keratinopathic Ichthyosis.
Acta dermato-venereologica96(4)473-8(2016 May)
Hotz A,Oji V,Bourrat E,Jonca N,Mazereeuw-Hautier J,Betz RC,Blume-Peytavi U,Stieler K,Morice-Picard F,Schönbuchner I,Markus S,Schlipf N,Fischer J


book

Intrafamilial phenotypic heterogeneity of epidermolytic ichthyosis associated with a new missense mutation in keratin 10.
Clinical and experimental dermatology41(3)290-3(2016 Apr)
Abdul-Wahab A,Takeichi T,Liu L,Stephens C,Akiyama M,McGrath JA


book

Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly.
PloS one10(7)e0132706(2015)
Bray DJ,Walsh TR,Noro MG,Notman R


 
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