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LOR cDNA ORF clone, Homo sapiens (human)

Gene Symbol LOR
Entrez Gene ID 4014
Full Name loricrin
General protein information
Preferred Names
loricrin
Names
loricrin
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q21

Summary This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

152445

Disorder Html: Vohwinkel syndrome with ichthyosis, 604117 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011509541 XP_011507843 loricrin isoform X1
NM_000427 NP_000418 loricrin


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LOR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu58761 XM_011509541 PREDICTED: Homo sapiens loricrin (LOR), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu19272 NM_000427 Homo sapiens loricrin (LOR), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu58761
Clone ID Related Accession (Same CDS sequence) XM_011509541
Accession Version XM_011509541.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 561bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product loricrin isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_004487.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGTCTTATC AGAAAAAGCA GCCCACCCCT CAGCCCCCAG TGGACTGCGT GAAGACCTCT 
GGCGGCGGTG GCGGTGGCGG CGGCAGCGGC GGTGGTGGCT GCGGCTTCTT CGGCGGCGGC
GGCTCAGGGG GCGGTAGCAG CGGTTCTGGC TGCGGCTACT CCGGCGGCGG TGGCTACTCT
GGCGGCGGCT CTGGCGGCGG CTCTGGCTGC GGCGGAGGCT CCTCTGGCGG CAGCGGCTCC
GGCTACGTCT CCTCGCAGCA GGTCACTCAG ACCTCGTGCG CGCCCCAGCC GAGTTACGGA
GGGGGGTCGT CCGGCGGCGG CGGCAGCGGC GGAAGCGGCT GCTTCTCCAG CGGCGGGGGC
GGCGGGAGCT CCGGCTGCGG CGGCGGCTCC TCCGGGATTG GCAGCGGCTG CATCATCAGT
GGCGGGGGCT CCGTCTGCGG AGGTGGTTCC TCTGGAGGCG GCGGCGGCGG CTCCTCCGTG
GGTGGCTCCG GGAGTGGCAA GGGCGTCCCG ATCTGCCACC AGACCCAGCA GAAGCAGGCG
CCTACCTGGC CGTCCAAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011507843.1
CDS123..683
Translation

Target ORF information:

RefSeq Version XM_011509541
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens loricrin (LOR), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011509541

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGTCTTATC AGAAAAAGCA GCCCACCCCT CAGCCCCCAG TGGACTGCGT GAAGACCTCT 
GGCGGCGGTG GCGGTGGCGG CGGCAGCGGC GGTGGTGGCT GCGGCTTCTT CGGCGGCGGC
GGCTCAGGGG GCGGTAGCAG CGGTTCTGGC TGCGGCTACT CCGGCGGCGG TGGCTACTCT
GGCGGCGGCT CTGGCGGCGG CTCTGGCTGC GGCGGAGGCT CCTCTGGCGG CAGCGGCTCC
GGCTACGTCT CCTCGCAGCA GGTCACTCAG ACCTCGTGCG CGCCCCAGCC GAGTTACGGA
GGGGGGTCGT CCGGCGGCGG CGGCAGCGGC GGAAGCGGCT GCTTCTCCAG CGGCGGGGGC
GGCGGGAGCT CCGGCTGCGG CGGCGGCTCC TCCGGGATTG GCAGCGGCTG CATCATCAGT
GGCGGGGGCT CCGTCTGCGG AGGTGGTTCC TCTGGAGGCG GCGGCGGCGG CTCCTCCGTG
GGTGGCTCCG GGAGTGGCAA GGGCGTCCCG ATCTGCCACC AGACCCAGCA GAAGCAGGCG
CCTACCTGGC CGTCCAAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19272
Clone ID Related Accession (Same CDS sequence) NM_000427
Accession Version NM_000427.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 939bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product loricrin
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC108290.1 and AL161636.21. This sequence is a reference standard in the RefSeqGene project. On Jun 19, 2006 this sequence version replaced gi:4557724. Sequence Note: Two alleles are present in unaffected individuals. The RefSeq record represents the allele present in the reference genome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC108290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGTCTTATC AGAAAAAGCA GCCCACCCCT CAGCCCCCAG TGGACTGCGT GAAGACCTCT 
GGCGGCGGTG GCGGTGGCGG CGGCAGCGGC GGTGGTGGCT GCGGCTTCTT CGGCGGCGGC
GGCTCAGGGG GCGGTAGCAG CGGTTCTGGC TGCGGCTACT CCGGCGGCGG TGGCTACTCT
GGCGGCGGCT GCGGCGGGGG CTCCTCCGGC GGCGGGGGCG GGGGCGGCAT TGGAGGCTGC
GGAGGGGGCT CCGGTGGGAG CGTCAAGTAC TCCGGAGGCG GCGGCTCCTC CGGCGGGGGC
TCTGGCTGTT TCTCCAGCGG TGGGGGCGGC TCCGGCTGCT TCTCCTCCGG TGGCGGCGGC
TCCTCCGGGG GCGGCTCCGG CTGCTTCTCC AGCGGTGGGG GCGGCTCCTC CGGGGGCGGC
TCCGGCTGCT TCTCCTCCGG CGGCGGCGGC TTCTCGGGCC AGGCGGTCCA GTGCCAGAGC
TACGGAGGCG TCTCTAGCGG CGGCTCCTCC GGGGGCGGCT CCGGCTGCTT CTCCAGCGGC
GGGGGCGGCG GCTCTGTCTG CGGCTACTCT GGCGGCGGCT CTGGCTGCGG CGGAGGCTCC
TCTGGCGGCA GCGGCTCCGG CTACGTCTCC TCGCAGCAGG TCACTCAGAC CTCGTGCGCG
CCCCAGCCGA GTTACGGAGG GGGGTCGTCC GGCGGCGGCG GCAGCGGCGG AAGCGGCTGC
TTCTCCAGCG GCGGGGGCGG CGGGAGCTCC GGCTGCGGCG GCGGCTCCTC CGGGATTGGC
AGCGGCTGCA TCATCAGTGG CGGGGGCTCC GTCTGCGGAG GTGGTTCCTC TGGAGGCGGC
GGCGGCGGCT CCTCCGTGGG TGGCTCCGGG AGTGGCAAGG GCGTCCCGAT CTGCCACCAG
ACCCAGCAGA AGCAGGCGCC TACCTGGCCG TCCAAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000418.2
CDS55..993
Misc Feature(1)639..639(+)
Exon (1)1..31
Gene:LOR
Gene Synonym:
Exon (2)32..1229
Gene:LOR
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000427
Organism Homo sapiens (human)
Definition Homo sapiens loricrin (LOR), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000427

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGTCTTATC AGAAAAAGCA GCCCACCCCT CAGCCCCCAG TGGACTGCGT GAAGACCTCT 
GGCGGCGGTG GCGGTGGCGG CGGCAGCGGC GGTGGTGGCT GCGGCTTCTT CGGCGGCGGC
GGCTCAGGGG GCGGTAGCAG CGGTTCTGGC TGCGGCTACT CCGGCGGCGG TGGCTACTCT
GGCGGCGGCT GCGGCGGGGG CTCCTCCGGC GGCGGGGGCG GGGGCGGCAT TGGAGGCTGC
GGAGGGGGCT CCGGTGGGAG CGTCAAGTAC TCCGGAGGCG GCGGCTCCTC CGGCGGGGGC
TCTGGCTGTT TCTCCAGCGG TGGGGGCGGC TCCGGCTGCT TCTCCTCCGG TGGCGGCGGC
TCCTCCGGGG GCGGCTCCGG CTGCTTCTCC AGCGGTGGGG GCGGCTCCTC CGGGGGCGGC
TCCGGCTGCT TCTCCTCCGG CGGCGGCGGC TTCTCGGGCC AGGCGGTCCA GTGCCAGAGC
TACGGAGGCG TCTCTAGCGG CGGCTCCTCC GGGGGCGGCT CCGGCTGCTT CTCCAGCGGC
GGGGGCGGCG GCTCTGTCTG CGGCTACTCT GGCGGCGGCT CTGGCTGCGG CGGAGGCTCC
TCTGGCGGCA GCGGCTCCGG CTACGTCTCC TCGCAGCAGG TCACTCAGAC CTCGTGCGCG
CCCCAGCCGA GTTACGGAGG GGGGTCGTCC GGCGGCGGCG GCAGCGGCGG AAGCGGCTGC
TTCTCCAGCG GCGGGGGCGG CGGGAGCTCC GGCTGCGGCG GCGGCTCCTC CGGGATTGGC
AGCGGCTGCA TCATCAGTGG CGGGGGCTCC GTCTGCGGAG GTGGTTCCTC TGGAGGCGGC
GGCGGCGGCT CCTCCGTGGG TGGCTCCGGG AGTGGCAAGG GCGTCCCGAT CTGCCACCAG
ACCCAGCAGA AGCAGGCGCC TACCTGGCCG TCCAAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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