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MEIG1 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol MEIG1
Entrez Gene ID 644890
Full Name meiosis/spermiogenesis associated 1
Synonyms SPATA39,bA2K17.3
General protein information
Preferred Names

meiosis/spermiogenesis associated 1

Names

meiosis expressed gene 1 protein homolog
meiosis expressed gene 1 homolog
spermatogenesis associated 39
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

10

10p13
Disorder MIM:

614174


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_024448136.1 XP_024303904.1 meiosis expressed gene 1 protein homolog isoform X1
NM_001080836.3 NP_001074305.1 meiosis expressed gene 1 protein homolog
NM_001080836.2 NP_001074305.1 meiosis expressed gene 1 protein homolog

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Meig1 NP_001128354.1
Xenopus tropicalis (tropical clawed frog) meig1 NP_001016522.1
Pan troglodytes (chimpanzee) MEIG1 XP_001139696.1
Gallus gallus (chicken) MEIG1 XP_001231713.1
Bos taurus (cattle) MEIG1 NP_001107996.2
Mus musculus (house mouse) Meig1 NP_032605.1
Homo sapiens (human) MEIG1 NP_001074305.1
Canis lupus familiaris (dog) MEIG1 XP_005617165.1
MEIG1 XP_001088746.2
Danio rerio (zebrafish) meig1 NP_001013488.1

Gene Ontology


Bibliography

Related articles in PubMed

Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice.
Teves ME, Jha KN, Song J, Nagarkatti-Gude DR, Herr JC, Foster JA, Strauss JF 3rd, Zhang Z
Andrology1(1)37-46(2013 Jan)

MEIG1 is essential for spermiogenesis in mice.
Zhang Z, Shen X, Gude DR, Wilkinson BM, Justice MJ, Flickinger CJ, Herr JC, Eddy EM, Strauss JF 3rd
Proceedings of the National Academy of Sciences of the United States of America106(40)17055-60(2009 Oct)

Creation of genome-wide protein expression libraries using random activation of gene expression.
Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S, Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L, Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N, Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J, Ducar M
Nature biotechnology19(5)440-5(2001 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MEIG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MEIG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu05544 NM_001080836.3
Latest version!		 Homo sapiens meiosis/spermiogenesis associated 1 (MEIG1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu80572 XM_024448136.1
Latest version!		 Homo sapiens meiosis/spermiogenesis associated 1 (MEIG1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $69.30
$99.00
View Old Accession Versions >>
OHu05544 NM_001080836.2 Homo sapiens meiosis/spermiogenesis associated 1 (MEIG1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu05544
Clone ID Related Accession (Same CDS sequence) NM_001080836.3 , NM_001080836.2
Accession Version NM_001080836.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 267bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-30
Organism Homo sapiens(human)
Product meiosis expressed gene 1 protein homolog
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL360083.27, AI694434.1, AA971146.1 and BG189536.1. On Nov 22, 2018 this sequence version replaced NM_001080836.2. ##Evidence-Data-START## Transcript exon combination :: HY044233.1, HY038331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000407572.6/ ENSP00000384334.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
ATGGCTAGTT CTGACGTAAA ACCAAAATCA GTAAGTCATG CCAAAAAATG GTCAGAAGAG 
ATAGAAAATC TGTACAGATT TCAACAAGCA GGATATCGGG ATGAAACCGA ATATAGACAA 
GTGAAACAAG TTTCTATGGT AGATCGTTGG CCGGAGACAG GATATGTGAA GAAACTTCAG 
AGAAGGGACA ATACGTTCTA TTACTACAAC AAACAGAGGG AATGTGATGA CAAAGAAGTC 
CACAAAGTGA AAATTTATGC TTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001074305.1
CDS200..466
Translation

Target ORF information:

RefSeq Version NM_001080836.3
Organism Homo sapiens(human)
Definition Homo sapiens meiosis/spermiogenesis associated 1 (MEIG1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001080836.3

ORF Insert Sequence:

1
61
121
181
241
ATGGCTAGTT CTGACGTAAA ACCAAAATCA GTAAGTCATG CCAAAAAATG GTCAGAAGAG 
ATAGAAAATC TGTACAGATT TCAACAAGCA GGATATCGGG ATGAAACCGA ATATAGACAA 
GTGAAACAAG TTTCTATGGT AGATCGTTGG CCGGAGACAG GATATGTGAA GAAACTTCAG 
AGAAGGGACA ATACGTTCTA TTACTACAAC AAACAGAGGG AATGTGATGA CAAAGAAGTC 
CACAAAGTGA AAATTTATGC TTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu05544
Clone ID Related Accession (Same CDS sequence) NM_001080836.3 , NM_001080836.2
Accession Version NM_001080836.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 267bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product meiosis expressed gene 1 protein homolog
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI694434.1, AA971146.1 and BG189536.1. On Sep 13, 2007 this sequence version replaced NM_001080836.1. ##Evidence-Data-START## Transcript exon combination :: HY224073.1, HY230535.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
ATGGCTAGTT CTGACGTAAA ACCAAAATCA GTAAGTCATG CCAAAAAATG GTCAGAAGAG 
ATAGAAAATC TGTACAGATT TCAACAAGCA GGATATCGGG ATGAAACCGA ATATAGACAA 
GTGAAACAAG TTTCTATGGT AGATCGTTGG CCGGAGACAG GATATGTGAA GAAACTTCAG 
AGAAGGGACA ATACGTTCTA TTACTACAAC AAACAGAGGG AATGTGATGA CAAAGAAGTC 
CACAAAGTGA AAATTTATGC TTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001074305.1
CDS149..415
Translation

Target ORF information:

RefSeq Version NM_001080836.2
Organism Homo sapiens(human)
Definition Homo sapiens meiosis/spermiogenesis associated 1 (MEIG1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001080836.2

ORF Insert Sequence:

1
61
121
181
241
ATGGCTAGTT CTGACGTAAA ACCAAAATCA GTAAGTCATG CCAAAAAATG GTCAGAAGAG 
ATAGAAAATC TGTACAGATT TCAACAAGCA GGATATCGGG ATGAAACCGA ATATAGACAA 
GTGAAACAAG TTTCTATGGT AGATCGTTGG CCGGAGACAG GATATGTGAA GAAACTTCAG 
AGAAGGGACA ATACGTTCTA TTACTACAAC AAACAGAGGG AATGTGATGA CAAAGAAGTC 
CACAAAGTGA AAATTTATGC TTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu80572
Clone ID Related Accession (Same CDS sequence) XM_024448136.1
Accession Version XM_024448136.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 360bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product meiosis expressed gene 1 protein homolog isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGGGCCCTG AGCCCTGCCC AGTGCAAGGC TCATTCCCGC CCAACAAACA CAGGTGTTGC 
TCTGATATTA TTGATAATAA GGCCTCTGTA ACCATGGCTA GTTCTGACGT AAAACCAAAA 
TCAGTAAGTC ATGCCAAAAA ATGGTCAGAA GAGATAGAAA ATCTGTACAG ATTTCAACAA 
GCAGGATATC GGGATGAAAC CGAATATAGA CAAGTGAAAC AAGTTTCTAT GGTAGATCGT 
TGGCCGGAGA CAGGATATGT GAAGAAACTT CAGAGAAGGG ACAATACGTT CTATTACTAC 
AACAAACAGA GGGAATGTGA TGACAAAGAA GTCCACAAAG TGAAAATTTA TGCTTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_024303904.1
CDS14..373
Translation

Target ORF information:

RefSeq Version XM_024448136.1
Organism Homo sapiens(human)
Definition Homo sapiens meiosis/spermiogenesis associated 1 (MEIG1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_024448136.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGGGCCCTG AGCCCTGCCC AGTGCAAGGC TCATTCCCGC CCAACAAACA CAGGTGTTGC 
TCTGATATTA TTGATAATAA GGCCTCTGTA ACCATGGCTA GTTCTGACGT AAAACCAAAA 
TCAGTAAGTC ATGCCAAAAA ATGGTCAGAA GAGATAGAAA ATCTGTACAG ATTTCAACAA 
GCAGGATATC GGGATGAAAC CGAATATAGA CAAGTGAAAC AAGTTTCTAT GGTAGATCGT 
TGGCCGGAGA CAGGATATGT GAAGAAACTT CAGAGAAGGG ACAATACGTT CTATTACTAC 
AACAAACAGA GGGAATGTGA TGACAAAGAA GTCCACAAAG TGAAAATTTA TGCTTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice.
Andrology1(1)37-46(2013 Jan)
Teves ME,Jha KN,Song J,Nagarkatti-Gude DR,Herr JC,Foster JA,Strauss JF 3rd,Zhang Z


book

MEIG1 is essential for spermiogenesis in mice.
Proceedings of the National Academy of Sciences of the United States of America106(40)17055-60(2009 Oct)
Zhang Z,Shen X,Gude DR,Wilkinson BM,Justice MJ,Flickinger CJ,Herr JC,Eddy EM,Strauss JF 3rd


book

Creation of genome-wide protein expression libraries using random activation of gene expression.
Nature biotechnology19(5)440-5(2001 May)
Harrington JJ,Sherf B,Rundlett S,Jackson PD,Perry R,Cain S,Leventhal C,Thornton M,Ramachandran R,Whittington J,Lerner L,Costanzo D,McElligott K,Boozer S,Mays R,Smith E,Veloso N,Klika A,Hess J,Cothren K,Lo K,Offenbacher J,Danzig J,Ducar M