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CCL4L2 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol CCL4L2
Entrez Gene ID 9560
Full Name C-C motif chemokine ligand 4 like 2
Synonyms AT744.2,CCL4L,SCYA4L,SCYQ4L2
General protein information
Preferred Names

C-C motif chemokine ligand 4 like 2

Names

C-C motif chemokine 4-like
MIP-1-beta
chemokine (C-C motif) ligand 4-like 2
macrophage inflammatory protein 1-beta
macrophage inflammatory protein-1b2
monocyte adherence-induced protein 5-alpha
small inducible cytokine A4-like

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

17

17q12

Summary This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014].
Disorder MIM:

610757


mRNA and Protein(s)

mRNA Protein Name
NM_001291474.1 NP_001278403.1 C-C motif chemokine 4-like isoform 6 precursor
NM_001291472.1 NP_001278401.1 C-C motif chemokine 4-like isoform 4 precursor
NM_001291469.1 NP_001278398.1 C-C motif chemokine 4-like isoform 2 precursor
NM_001291471.1 NP_001278400.1 C-C motif chemokine 4-like isoform 3 precursor
NM_001291470.1 NP_001278399.1 C-C motif chemokine 4-like isoform 2 precursor
NM_001291475.1 NP_001278404.1 C-C motif chemokine 4-like isoform 7 precursor
NM_001291473.1 NP_001278402.1 C-C motif chemokine 4-like isoform 5 precursor
NM_001291468.1 NP_001278397.1 C-C motif chemokine 4-like isoform 1 precursor



Related articles in PubMed

Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection.
Suviolahti E, Ge S, Nast CC, Mirocha J, Karasyov A, White M, Jordan SC, Toyoda M
Transplant immunology32(1)9-17(2015 Jan)

Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes.
Bharuthram A, Paximadis M, Picton AC, Tiemessen CT
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2528-35(2014 Jul)

CCL4L polymorphisms and CCL4/CCL4L serum levels are associated with psoriasis severity.
Pedrosa E, Carretero-Iglesia L, Boada A, Colobran R, Faner R, Pujol-Autonell I, Palou E, Esteve A, Pujol-Borrell R, Ferrándiz C, Juan M, Carrascosa JM
The Journal of investigative dermatology131(9)1830-7(2011 Sep)

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.
Colobran R, Pedrosa E, Carretero-Iglesia L, Juan M
Clinical and experimental immunology162(1)41-52(2010 Oct)

Chemokine expression patterns in the systemic and genital tract compartments are associated with HIV-1 infection in women from Benin.
Lajoie J, Poudrier J, Massinga Loembe M, Guédou F, Leblond F, Labbé AC, Alary M, Roger M
Journal of clinical immunology30(1)90-8(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3, CCL4/CCL4L1/CCL4L2, CD160, IFNG, NR4A3 and XCL1/XCL2) were analyzed in 127 kidney biopsies
Title: Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection.

PCR results show that lower copy numbers of CCL4L2 are observed in the Caucasian population nd higher copy numbers are observed in the Black population of South Africa.
Title: Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes.

CCL4L1 allele frequency is higher in severe psoriasis, whereas CCL4L2 is more frequent in patients with a milder disease.
Title: CCL4L polymorphisms and CCL4/CCL4L serum levels are associated with psoriasis severity.

Studies indicate that complete phenotypic impact requires dissecting the combinatorial genomic complexity posed by various proportions of distinct CCL3L and CCL4L genes among individuals.
Title: Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.

higher level of expression at systemic level is associated with protection from HIV-1 infection in women from Benin
Title: Chemokine expression patterns in the systemic and genital tract compartments are associated with HIV-1 infection in women from Benin.

The following CCL4L2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL4L2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu16068 NM_001291468.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16099 NM_001291469.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2b1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16100 NM_001291470.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2b2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16101 NM_001291471.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2c, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16102 NM_001291472.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2d, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16103 NM_001291473.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2e, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16104 NM_001291474.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2bdelta2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16105 NM_001291475.1
Latest version!
Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2f, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16068
Clone ID Related Accession (Same CDS sequence) NM_001291468.1
Accession Version NM_001291468.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 264bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766450.1. Transcript Variant: This variant (CCL4L2) encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766450.1, CD559275.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGGCAAGCA AGTCTGCGCT GACCCCAGTG AGTCCTGGGT CCAGGAGTAC
GTGTATGACC TGGAACTGAA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278397.1
CDS80..343
Misc Feature(1)53..55
Misc Feature(2)170..331
Misc Feature(3)order(179..193,197..220,248..253,302..334)
Misc Feature(4)order(185..187,191..193,230..232,236..238,251..253,266..271,281..289,305..310,317..322,329..334)
Misc Feature(5)order(185..187,191..193,242..244,248..253,269..271,278..280,284..286)
Misc Feature(6)order(185..187,269..271,281..283)
Misc Feature(7)order(185..193,197..220)
Misc Feature(8)order(191..193,230..232,236..238,266..268,281..283,287..289,305..310,317..322,329..334)
Misc Feature(9)order(197..205,212..220,275..277)
Misc Feature(10)order(236..238,257..259,296..298,302..304,311..316,323..325)
Misc Feature(11)248..253
Exon (1)1..155
Exon (2)156..270
Exon (3)271..652
Translation

Target ORF information:

RefSeq Version NM_001291468.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291468.1

ORF Insert Sequence:

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGGCAAGCA AGTCTGCGCT GACCCCAGTG AGTCCTGGGT CCAGGAGTAC
GTGTATGACC TGGAACTGAA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16099
Clone ID Related Accession (Same CDS sequence) NM_001291469.1
Accession Version NM_001291469.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 195bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766451.1. Transcript Variant: This variant (CCL4L2b1) uses an alternate splice site in the 3' terminal exon, and it thus contains an early termination codon and differs in its 3' UTR, compared to variant CCL4L2. The encoded isoform (2) is shorter at the C-terminus, compared to isoform 1. Both variants CCL4L2b1 and CCL4L2b2 encode isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766451.1, BC092445.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278398.1
CDS80..274
Misc Feature(1)53..55
Misc Feature(2)170..>271
Misc Feature(3)order(185..193,206..220)
Misc Feature(4)order(239..241,257..259)
Exon (1)1..155
Exon (2)156..270
Exon (3)271..856
Translation

Target ORF information:

RefSeq Version NM_001291469.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2b1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291469.1

ORF Insert Sequence:

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16100
Clone ID Related Accession (Same CDS sequence) NM_001291470.1
Accession Version NM_001291470.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 195bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766452.1. Transcript Variant: This variant (CCL4L2b2) fails to splice out the 3'-most intron, and it thus contains an early termination codon and differs in its 3' UTR, compared to variant CCL4L2. The encoded isoform (2) is shorter at the C-terminus, compared to isoform 1. Both variants CCL4L2b1 and CCL4L2b2 encode isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766452.1, CD559248.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278399.1
CDS80..274
Misc Feature(1)53..55
Misc Feature(2)170..>271
Misc Feature(3)order(185..193,206..220)
Misc Feature(4)order(239..241,257..259)
Exon (1)1..155
Exon (2)156..1258
Translation

Target ORF information:

RefSeq Version NM_001291470.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2b2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291470.1

ORF Insert Sequence:

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16101
Clone ID Related Accession (Same CDS sequence) NM_001291471.1
Accession Version NM_001291471.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 312bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766453.1. Transcript Variant: This variant (CCL4L2c) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (3) has a distinct C-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766453.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT CCCATCCACC
AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA GGCAAGGGAT
AAAGCCAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278400.1
CDS80..391
Misc Feature(1)53..55
Misc Feature(2)170..>271
Misc Feature(3)order(185..193,206..220)
Misc Feature(4)order(239..241,257..259)
Exon (1)1..155
Exon (2)156..270
Exon (3)271..836
Translation

Target ORF information:

RefSeq Version NM_001291471.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2c, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291471.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT CCCATCCACC
AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA GGCAAGGGAT
AAAGCCAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16102
Clone ID Related Accession (Same CDS sequence) NM_001291472.1
Accession Version NM_001291472.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 291bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 4 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766454.1. Transcript Variant: This variant (CCL4L2d) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (4) has a distinct C-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGCTGCTCC GGGAAGGATC CCATCCACCA GAGCTGCCCC ACATGGACCA
TGGTCAGGCA GAGGAAGATG CCTACCACAG GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278401.1
CDS80..370
Misc Feature(1)53..55
Misc Feature(2)170..322
Misc Feature(3)order(185..193,206..220)
Misc Feature(4)order(239..241,257..259)
Exon (1)1..155
Exon (2)156..270
Exon (3)271..815
Translation

Target ORF information:

RefSeq Version NM_001291472.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2d, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291472.1

ORF Insert Sequence:

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGCTGCTCC GGGAAGGATC CCATCCACCA GAGCTGCCCC ACATGGACCA
TGGTCAGGCA GAGGAAGATG CCTACCACAG GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16103
Clone ID Related Accession (Same CDS sequence) NM_001291473.1
Accession Version NM_001291473.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 261bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 5 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766455.1. Transcript Variant: This variant (CCL4L2e) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (5) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766455.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGCTGCCCC ACATGGACCA TGGTCAGGCA GAGGAAGATG CCTACCACAG
GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278402.1
CDS80..340
Misc Feature(1)53..55
Misc Feature(2)170..>274
Misc Feature(3)order(185..193,206..220)
Misc Feature(4)order(239..241,257..259)
Exon (1)1..155
Exon (2)156..270
Exon (3)271..785
Translation

Target ORF information:

RefSeq Version NM_001291473.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2e, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291473.1

ORF Insert Sequence:

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGCTGCCCC ACATGGACCA TGGTCAGGCA GAGGAAGATG CCTACCACAG
GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16104
Clone ID Related Accession (Same CDS sequence) NM_001291474.1
Accession Version NM_001291474.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 207bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 6 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766457.1. Transcript Variant: This variant (CCL4L2bdelta2) lacks an alternate internal exon and uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (6) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766457.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159764, SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAACTAA ATCCAGTGAG TGGAAGTTAC AGGGAGTCTG CTTCCAGTGC
TGCTCCGGGA AGGATCCCAT CCACCAGAGC TGCCCCACAT GGACCATGGT CAGGCAGAGG
AAGATGCCTA CCACAGGCAA GGGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278403.1
CDS80..286
Misc Feature(1)53..55
Exon (1)1..155
Exon (2)156..741
Translation

Target ORF information:

RefSeq Version NM_001291474.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2bdelta2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291474.1

ORF Insert Sequence:

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAACTAA ATCCAGTGAG TGGAAGTTAC AGGGAGTCTG CTTCCAGTGC
TGCTCCGGGA AGGATCCCAT CCACCAGAGC TGCCCCACAT GGACCATGGT CAGGCAGAGG
AAGATGCCTA CCACAGGCAA GGGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16105
Clone ID Related Accession (Same CDS sequence) NM_001291475.1
Accession Version NM_001291475.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 312bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-05-02
Organism Homo sapiens(Human)
Product C-C motif chemokine 4-like isoform 7 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766458.1. Transcript Variant: This variant (CCL4L2f) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (7) has a distinct C-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766458.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGAGTGGAA GTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT
CCCATCCACC AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA
GGCAAGGGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278404.1
CDS80..391
Misc Feature(1)53..55
Misc Feature(2)170..>295
Misc Feature(3)order(185..193,206..220)
Misc Feature(4)order(239..241,257..259)
Exon (1)1..155
Exon (2)156..270
Exon (3)271..846
Translation

Target ORF information:

RefSeq Version NM_001291475.1
Organism Homo sapiens(Human)
Definition Homo sapiens C-C motif chemokine ligand 4 like 2 (CCL4L2), transcript variant CCL4L2f, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291475.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGAGTGGAA GTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT
CCCATCCACC AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA
GGCAAGGGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection.
Transplant immunology32(1)9-17(2015 Jan)
Suviolahti E,Ge S,Nast CC,Mirocha J,Karasyov A,White M,Jordan SC,Toyoda M


book

Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2528-35(2014 Jul)
Bharuthram A,Paximadis M,Picton AC,Tiemessen CT


book

CCL4L polymorphisms and CCL4/CCL4L serum levels are associated with psoriasis severity.
The Journal of investigative dermatology131(9)1830-7(2011 Sep)
Pedrosa E,Carretero-Iglesia L,Boada A,Colobran R,Faner R,Pujol-Autonell I,Palou E,Esteve A,Pujol-Borrell R,Ferrándiz C,Juan M,Carrascosa JM


book

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.
Clinical and experimental immunology162(1)41-52(2010 Oct)
Colobran R,Pedrosa E,Carretero-Iglesia L,Juan M


book

Chemokine expression patterns in the systemic and genital tract compartments are associated with HIV-1 infection in women from Benin.
Journal of clinical immunology30(1)90-8(2010 Jan)
Lajoie J,Poudrier J,Massinga Loembe M,Guédou F,Leblond F,Labbé AC,Alary M,Roger M


 
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