Gene Symbol | Nps |
Entrez Gene ID | 100043254 |
Full Name | neuropeptide S |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Nps cDNA ORF clone
Gene Symbol | Nps |
Entrez Gene ID | 100043254 |
Full Name | neuropeptide S |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001163611.1 | NP_001157083.1 | neuropeptide S precursor |
Neuropeptide S (NPS) is a neuropeptide with cellular actions in arousal and anxiety-related nuclei: Functional implications for effects of NPS on wakefulness and mood.
Roncac? V, Polli FS, Zojicic M, Kohlmeier KA
Neuropharmacology126292-317(2017 Nov)
Neuropeptide S precursor knockout mice display memory and arousal deficits.
Liu X, Si W, Garau C, J?ngling K, Pape HC, Schulz S, Reinscheid RK
The European journal of neuroscience46(1)1689-1700(2017 Jul)
Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.
Shao YF, Wang C, Xie JF, Kong XP, Xin L, Dong CY, Li J, Ren WT, Hou YP
Brain structure & function221(6)3327-36(2016 07)
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.
Ruzza C, Asth L, Guerrini R, Trapella C, Gavioli EC
Neuropharmacology971-6(2015 Oct)
Neuropeptide S Increases locomotion activity through corticotropin-releasing factor receptor 1 in substantia nigra of mice.
Li MS, Peng YL, Jiang JH, Xue HX, Wang P, Zhang PJ, Han RW, Chang M, Wang R
Peptides71196-201(2015 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Findings demonstrate that neuropeptide S, via selective activation of the neurons bearing neuropeptide S receptor in the subiculum complex, ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 in mice.
Title: Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.
Study demonstrated that NPS produces anti-aggressive effects in mice through the selective activation of NPSR and that the endogenous NPS/NPSR system can exert a role in the control of aggressiveness levels under the present experimental conditions
Title: Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.
these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.
Title: Neuropeptide S Increases locomotion activity through corticotropin-releasing factor receptor 1 in substantia nigra of mice.
These data provide evidence for a direct interaction between the corticotropin-releasing factor and the NPS system and thereby extend previous observations of NPS-modulated stress responsiveness towards a mechanistic level.
Title: Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor.
These data demonstrate that the distribution pattern of the central neuropeptide S system is only partially conserved between mice and rats.
Title: Anatomical characterization of the neuropeptide S system in the mouse brain by in situ hybridization and immunohistochemistry.
The following Nps gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nps cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09242 | |
Clone ID Related Accession (Same CDS sequence) | NM_001163611.1 | |
Accession Version | NM_001163611.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 270bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-22 | |
Organism | Mus musculus(house mouse) | |
Product | neuropeptide S precursor | |
Comment | Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AC136641.3 and AC131669.3. On or before Jul 26, 2009 this sequence version replaced XM_001479305.1, XM_001479833.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164136, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATTGGCT CGTTAAAACT CAGCTTCGTC TTAGCTCTGT CGCTGTCTGT AATGCACGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001157083.1 |
CDS | 21..290 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001163611.1 |
1 | ATGATTGGCT CGTTAAAACT CAGCTTCGTC TTAGCTCTGT CGCTGTCTGT AATGCACGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Neuropeptide S (NPS) is a neuropeptide with cellular actions in arousal and anxiety-related nuclei: Functional implications for effects of NPS on wakefulness and mood. |
Neuropeptide S precursor knockout mice display memory and arousal deficits. |
Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex. |
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor. |
Neuropeptide S Increases locomotion activity through corticotropin-releasing factor receptor 1 in substantia nigra of mice. |