Gene Symbol | Efna1 |
Entrez Gene ID | 13636 |
Full Name | ephrin A1 |
Synonyms | AI325262,B61,Efl1,Epl1,Eplg1,Lerk1 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Efna1 cDNA ORF clone
gRNAs
Gene Symbol | Efna1 |
Entrez Gene ID | 13636 |
Full Name | ephrin A1 |
Synonyms | AI325262,B61,Efl1,Epl1,Eplg1,Lerk1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001162425.1 | NP_001155897.1 | ephrin-A1 isoform 2 |
NM_010107.4 | NP_034237.3 | ephrin-A1 isoform 1 precursor |
Rattus norvegicus (Norway rat) | Efna1 | NP_446051.2 |
Homo sapiens (human) | EFNA1 | NP_004419.2 |
LOC717399 | XP_001115135.1 | |
Mus musculus (house mouse) | Efna1 | NP_034237.3 |
Danio rerio (zebrafish) | efna1b | NP_957077.2 |
Xenopus tropicalis (tropical clawed frog) | efna1 | NP_001011206.1 |
Pan troglodytes (chimpanzee) | EFNA1 | XP_001141980.2 |
Canis lupus familiaris (dog) | EFNA1 | XP_852071.1 |
Danio rerio (zebrafish) | efna1a | NP_956891.1 |
Bos taurus (cattle) | EFNA1 | NP_001029464.1 |
Anatomical-Molecular Distribution of EphrinA1 in Infarcted Mouse Heart Using MALDI Mass Spectrometry Imaging.
Lefcoski S, Kew K, Reece S, Torres MJ, Parks J, Reece S, de Castro Br?s LE, Virag JAI
Journal of the American Society for Mass Spectrometry(2018 Jan)
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstr?m E, Pachnis V, Marklund U
Gastroenterology(2017 Oct)
All-trans retinoic acid attenuates bleomycin-induced pulmonary fibrosis via downregulating EphA2-EphrinA1 signaling.
Leem AY, Shin MH, Douglas IS, Song JH, Chung KS, Kim EY, Jung JY, Kang YA, Chang J, Kim YS, Park MS
Biochemical and biophysical research communications491(3)721-726(2017 09)
Activation of EphA1-Epha receptor axis attenuates diabetic nephropathy in mice.
Li Y, Yan H, Wang F, Huang S, Zhang Y, Wang Z, Zhong M, Zhang W
Biochemical and biophysical research communications486(3)693-699(2017 05)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Collectively, these data suggest that ATRA attenuates bleomycin-induced pulmonary fibrosis by regulating EphA2-EphrinA1 and PI3K-Akt signaling.
Title: All-trans retinoic acid attenuates bleomycin-induced pulmonary fibrosis via downregulating EphA2-EphrinA1 signaling.
Activation of EphA1-Epha receptor axis attenuates diabetic nephropathy in mice.
Title: Activation of EphA1-Epha receptor axis attenuates diabetic nephropathy in mice.
Following ephrin-A1 stimulation, truncated EphA2 did not detectably interfere with the phosphorylation of endogenous EphA2, and it potentiated cell adhesion possibly through modulation of integrin avidity.
Title: Truncated EphA2 likely potentiates cell adhesion via integrins as well as infiltration and/or lodgment of a monocyte/macrophage cell line in the red pulp and marginal zone of the mouse spleen, where ephrin-A1 is prominently expressed in the vasculature.
Lipopolysaccharide exposure significantly up-regulated EphA2 and EphrinA1 expression.
Title: Inhibition of EphA2/EphrinA1 signal attenuates lipopolysaccharide-induced lung injury.
S100A8 and ephrin-A1 contribute to lung metastasis.
Title: Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 4.
The following Efna1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Efna1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu13395 | |
Clone ID Related Accession (Same CDS sequence) | NM_001162425.1 | |
Accession Version | NM_001162425.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-20 | |
Organism | Mus musculus(house mouse) | |
Product | ephrin-A1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK079266.1 and AC132327.3. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK079266.1, BB628121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGCGAT ACACACTGTA CATGGTGGAA CACCAGGAGT ATGTGGCATG CCAACCCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001155897.1 |
CDS | 257..685 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGAGCGAT ACACACTGTA CATGGTGGAA CACCAGGAGT ATGTGGCATG CCAACCCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13675 | |
Clone ID Related Accession (Same CDS sequence) | NM_010107.4 | |
Accession Version | NM_010107.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-20 | |
Organism | Mus musculus(house mouse) | |
Product | ephrin-A1 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN696019.1, AK009144.1 and AC132327.3. On Jul 2, 2009 this sequence version replaced NM_010107.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK009144.1, BC002046.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGTTCC TTTGGGCCCC TCTCTTGGGT CTGTGCTGCA GTCTGGCCGC TGCTGACCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_034237.3 |
CDS | 104..721 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGAGTTCC TTTGGGCCCC TCTCTTGGGT CTGTGCTGCA GTCTGGCCGC TGCTGACCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Anatomical-Molecular Distribution of EphrinA1 in Infarcted Mouse Heart Using MALDI Mass Spectrometry Imaging. |
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. |
All-trans retinoic acid attenuates bleomycin-induced pulmonary fibrosis via downregulating EphA2-EphrinA1 signaling. |
Activation of EphA1-Epha receptor axis attenuates diabetic nephropathy in mice. |