Gene Symbol | Opn1mw |
Entrez Gene ID | 14539 |
Full Name | opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) |
Synonyms | Gcp |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Opn1mw cDNA ORF clone
gRNAs
Gene Symbol | Opn1mw |
Entrez Gene ID | 14539 |
Full Name | opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) |
Synonyms | Gcp |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_008106.2 | NP_032132.1 | medium-wave-sensitive opsin 1 |
Bos taurus (cattle) | OPN1LW | NP_776991.1 |
Gallus gallus (chicken) | OPN1LW | NP_990771.1 |
Danio rerio (zebrafish) | opn1lw1 | NP_571250.1 |
Pan troglodytes (chimpanzee) | OPN1LW | XP_003317827.1 |
Rattus norvegicus (Norway rat) | Opn1mw | NP_446000.1 |
Mus musculus (house mouse) | Opn1mw | NP_032132.1 |
Danio rerio (zebrafish) | opn1lw2 | NP_001002443.1 |
Homo sapiens (human) | OPN1LW | NP_064445.2 |
Canis lupus familiaris (dog) | OPN1LW | NP_001184001.1 |
Xenopus tropicalis (tropical clawed frog) | opn1lw | NP_001096331.1 |
A thyroid hormone receptor that is required for the development of green cone photoreceptors.
Ng L, Hurley JB, Dierks B, Srinivas M, Salt? C, Vennstr?m B, Reh TA, Forrest D
Nature genetics27(1)94-8(2001 Jan)
The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.
Applebury ML, Antoch MP, Baxter LC, Chun LL, Falk JD, Farhangfar F, Kage K, Krzystolik MG, Lyass LA, Robbins JT
Neuron27(3)513-23(2000 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
quantitative FRET analysis in acutely isolated cone OS revealed that the cone degeneration-causing V268I mutation in peripherin-2 selectively reduced binding to M-opsin without affecting the peripherin-2 interaction to S-opsin or rhodopsin
Title: Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.
Here, the creation and validation of two lines of genetically engineered mice that can be used to study disease-causing variants of human L/M-opsins, in vivo, are described.
Title: S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.
ectopically expressed cTalpha 1) forms a heterotrimeric complex with rod Gbeta(1)gamma(1), and substitutes equally for rTalpha in generating photoresponses initiated by either rhodopsin or S-cone opsin
Title: Functional comparison of rod and cone G?(t) on the regulation of light sensitivity.
Luciferase expression driven by the midwavelength sensitive opsin intron 3-4 region was only slightly increased by THRB2, and rather enhanced by COUP-TFII.
Title: Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor ?2 and COUP-TFII.
alpha transducin and opsin have roles in mouse photoreceptor cell responses to light and dark
Title: Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.
The following Opn1mw gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Opn1mw cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu17541 | |
Clone ID Related Accession (Same CDS sequence) | NM_008106.2 | |
Accession Version | NM_008106.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | medium-wave-sensitive opsin 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK149287.1 and AF011389.1. On Feb 16, 2006 this sequence version replaced NM_008106.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014826.1, AF190672.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCAAA GGCTTACAGG TGAACAGACA CTGGACCACT ATGAGGATAG CACCCATGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032132.1 |
CDS | 42..1121 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCCCAAA GGCTTACAGG TGAACAGACA CTGGACCACT ATGAGGATAG CACCCATGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A thyroid hormone receptor that is required for the development of green cone photoreceptors. |
The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning. |