Gene Symbol | Gja10 |
Entrez Gene ID | 14610 |
Full Name | gap junction protein, alpha 10 |
Synonyms | Cx-57,Cx59,cx57 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gja10 cDNA ORF clone
gRNAs
Gene Symbol | Gja10 |
Entrez Gene ID | 14610 |
Full Name | gap junction protein, alpha 10 |
Synonyms | Cx-57,Cx59,cx57 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_010289.2 | NP_034419.2 | gap junction alpha-10 protein precursor |
Bos taurus (cattle) | GJA10 | XP_005210941.1 |
Homo sapiens (human) | GJA10 | NP_115991.1 |
Pan troglodytes (chimpanzee) | GJA10 | XP_527450.1 |
Rattus norvegicus (Norway rat) | Gja10 | NP_001166979.1 |
Mus musculus (house mouse) | Gja10 | NP_034419.2 |
GJA10 | XP_001092621.2 | |
Canis lupus familiaris (dog) | GJA10 | XP_003639446.2 |
Gallus gallus (chicken) | GJA10 | XP_001235097.1 |
Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells.
Str?h S, Puller C, Swirski S, H?lzel MB, van der Linde LIS, Segelken J, Schultz K, Block C, Monyer H, Willecke K, Weiler R, Greschner M, Janssen-Bienhold U, Dedek K
The Journal of neuroscience : the official journal of the Society for Neuroscience(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study showed that mouse horizontal cells establish a coupled dendritic network by Cx57 and two coupled axon terminal networks, one made of Cx50 and the other made of Cx57 channels
Title: Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions.
Cx57 positive cells are clustered into small groups to form different patterns in the olfactory epithelium; within the sensory epithelial layer, hybridization signal is visible in sublayers containing cell bodies of basal cells and olfactory neurons.
Title: Expression of connexin 57 in the olfactory epithelium and olfactory bulb.
The study confirmed the expression of Cx57 in the horizontal cells of the retinal outer plexiform layer, the cerebellum and pre-cerebellar.
Title: Expression of connexin57 in mouse development and in harmaline-tremor model.
connexin genes Gjd2 coding for mCx36, Gjc1 coding for mCx45 and Gja10 coding for mCx57 in the mouse, a subset of 4 connexin genes, including the unique GJA9 (Cx59) and GJA10 (Cx62), could be detected at least as transcript isoforms in the human retina.
Title: Expression of connexin genes in the human retina.
the open channel probability of Cx57 gap junctions can be modulated by pH(i) with very high efficiency in the physiologically relevant range and may explain pH-dependent regulation of cell-cell coupling in horizontal cell in the retina
Title: Gating, permselectivity and pH-dependent modulation of channels formed by connexin57, a major connexin of horizontal cells in the mouse retina.
The following Gja10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gja10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu18850 | |
Clone ID Related Accession (Same CDS sequence) | NM_010289.2 | |
Accession Version | NM_010289.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | gap junction alpha-10 protein precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL831746.5. On Nov 1, 2006 this sequence version replaced NM_010289.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. |
1 | ATGGGAGATT GGAATTTACT GGGTGGCATC CTAGAGGAAG TCCACTCCCA CTCCACTATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_034419.2 |
CDS | 1..1518 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGGAGATT GGAATTTACT GGGTGGCATC CTAGAGGAAG TCCACTCCCA CTCCACTATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells. |