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Ifnar2 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Ifnar2
Entrez Gene ID 15976
Full Name interferon (alpha and beta) receptor 2
Synonyms AI747302,Ifnar-2
General protein information
Preferred Names

interferon (alpha and beta) receptor 2

Names

interferon alpha/beta receptor 2
IFN-R-2
IFN-alpha/beta receptor 2
interferon receptor 2a'
interferon receptor 2c
type I interferon alpha/beta receptor 2a
type I interferon receptor 2
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

16

16 C3.3|16 52.82 cM

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001347258.1 NP_001334187.1 interferon alpha/beta receptor 2 isoform c precursor
XM_011246100.2 XP_011244402.1 interferon alpha/beta receptor 2 isoform X1
XM_011246100.3 XP_011244402.1 interferon alpha/beta receptor 2 isoform X1
NM_010509.2 NP_034639.2 interferon alpha/beta receptor 2 isoform a precursor
XM_017316882.1 XP_017172371.1 interferon alpha/beta receptor 2 isoform X2
NM_001110498.1 NP_001103968.1 interferon alpha/beta receptor 2 isoform b precursor

Pathways from BioSystems


Homologies


Mus musculus (house mouse) Ifnar2 NP_034639.2
IFNAR2 XP_001092342.1
Bos taurus (cattle) IFNAR2 NP_776978.1
Gallus gallus (chicken) IFNAR2 NP_990189.1
Rattus norvegicus (Norway rat) Ifnar2 XP_006248170.1
Canis lupus familiaris (dog) IFNAR2 XP_005638921.1
Homo sapiens (human) IFNAR2 NP_001276054.1
Pan troglodytes (chimpanzee) IFNAR2 XP_001164897.1
Canis lupus familiaris (dog) LOC100856468 XP_005638896.1

Gene Ontology


Bibliography

Related articles in PubMed

Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1?.
Zhu Q, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950)198(11)4210-4215(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We found that STAT-1(-/-) MRL lpr m, but not IRF-9(-/-) or IFNAR-2(-/-) mice, developed interstitial nephritis characterized by infiltration with RORgammat-positive lymphocytes, macrophages, and eosinophils.
Title: Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1.

mTORC2 has a central role in IFNgamma signaling and type II IFN responses
Title: Interferon ? (IFN?) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses.

In this study, we elucidate the in vivo importance of the soluble type I IFNAR, soluble (s)IFNAR2a
Title: Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock.

ability of L. pneumophila to induce IFN-I expression was found to be dependent on IRF-3, but not NF-kappaB. Secreted IFN-Is then in turn suppress the intracellular replication of L. pneumophila
Title: Interferons direct an effective innate response to Legionella pneumophila infection.

Our studies provide a critical link between the IFN-I pathway and the regulation of TLR-specific B-cell responses in a murine model of Systemic lupus erythematosus
Title: Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus.

The following Ifnar2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ifnar2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu22218 NM_001110498.1
Latest version!		 Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
OMu52677 NM_001347258.1
Latest version!		 Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OMu79270 XM_017316882.1
Latest version!		 Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OMu67987 XM_011246100.3
Latest version!		 Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00
OMu22267 NM_010509.2
Latest version!		 Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $300.30
$429.00
View Old Accession Versions >>
OMu67987 XM_011246100.2 Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu22218
Clone ID Related Accession (Same CDS sequence) NM_001110498.1
Accession Version NM_001110498.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 747bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-26
Organism Mus musculus(house mouse)
Product interferon alpha/beta receptor 2 isoform b precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX515017.1, AK003185.1 and BE993108.1. Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 1, that results in a frameshift. It encodes isoform b, which has a shorter and distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK003185.1, AF013486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCGTTCAC GGTGCACCGT CTCTGCCGTC GGTCTCCTCA GCTTGTGTCT TGTGGTGTCT 
GCGAGCCTAG AGACTATCAC ACCGTCTGCT TTTGATGGGT ATCCAGATGA ACCTTGCACT 
ATAAACATAA CAATACGAAA TTCCCGGCTA ATTTTATCCT GGGAATTAGA GAACAAGTCT 
GGCCCACCCG CTAACTACAC CCTCTGGTAC ACAGTCATGA GCAAAGACGA AAATCTGACG 
AAGGTTAAGA ACTGTTCAGA TACCACGAAG TCATCATGTG ACGTGACAGA TAAGTGGTTG 
GAGGGCATGG AGAGCTACGT CGTCGCCATC GTCATAGTGC ACAGAGGGGA CTTGACCGTG 
TGCCGCTGCT CAGACTACAT CGTGCCTGCA AACGCTCCTC TTGAGCCGCC AGAATTTGAG 
ATCGTTGGCT TTACAGACCA CATAAACGTG ACGATGGAAT TTCCACCTGT CACTTCCAAA 
ATAATCCAGG AAAAGATGAA GACTACACCC TTTGTCATCA AAGAACAGAT AGGGGACAGC 
GTTAGGAAGA AGCACGAGCC CAAAGTGAAT AATGTCACTG GGAACTTCAC ATTTGTCCTT 
AGAGACTTAC TTCCAAAGAC AAACTACTGT GTATCTCTTT ATTTTGATGA TGACCCCGCA 
ATAAAATCTC CCTTAAAATG CATCGTCCTT CAGCCTGGCC AGGAATCAGG TATGGCTAGG 
TTTTTAAAAT TTGCACTATT GTTTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001103968.1
CDS331..1077
Translation

Target ORF information:

RefSeq Version NM_001110498.1
Organism Mus musculus(house mouse)
Definition Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001110498.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCGTTCAC GGTGCACCGT CTCTGCCGTC GGTCTCCTCA GCTTGTGTCT TGTGGTGTCT 
GCGAGCCTAG AGACTATCAC ACCGTCTGCT TTTGATGGGT ATCCAGATGA ACCTTGCACT 
ATAAACATAA CAATACGAAA TTCCCGGCTA ATTTTATCCT GGGAATTAGA GAACAAGTCT 
GGCCCACCCG CTAACTACAC CCTCTGGTAC ACAGTCATGA GCAAAGACGA AAATCTGACG 
AAGGTTAAGA ACTGTTCAGA TACCACGAAG TCATCATGTG ACGTGACAGA TAAGTGGTTG 
GAGGGCATGG AGAGCTACGT CGTCGCCATC GTCATAGTGC ACAGAGGGGA CTTGACCGTG 
TGCCGCTGCT CAGACTACAT CGTGCCTGCA AACGCTCCTC TTGAGCCGCC AGAATTTGAG 
ATCGTTGGCT TTACAGACCA CATAAACGTG ACGATGGAAT TTCCACCTGT CACTTCCAAA 
ATAATCCAGG AAAAGATGAA GACTACACCC TTTGTCATCA AAGAACAGAT AGGGGACAGC 
GTTAGGAAGA AGCACGAGCC CAAAGTGAAT AATGTCACTG GGAACTTCAC ATTTGTCCTT 
AGAGACTTAC TTCCAAAGAC AAACTACTGT GTATCTCTTT ATTTTGATGA TGACCCCGCA 
ATAAAATCTC CCTTAAAATG CATCGTCCTT CAGCCTGGCC AGGAATCAGG TATGGCTAGG 
TTTTTAAAAT TTGCACTATT GTTTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu67987
Clone ID Related Accession (Same CDS sequence) XM_011246100.2 , XM_011246100.3
Accession Version XM_011246100.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1236bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product interferon alpha/beta receptor 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246100.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAGAGCT ACGTCGTCGC CATCGTCATA GTGCACAGAG GGGACTTGAC CGTGTGCCGC 
TGCTCAGACT ACATCGTGCC TGCAAACGCT CCTCTTGAGC CGCCAGAATT TGAGATCGTT 
GGCTTTACAG ACCACATAAA CGTGACGATG GAATTTCCAC CTGTCACTTC CAAAATAATC 
CAGGAAAAGA TGAAGACTAC ACCCTTTGTC ATCAAAGAAC AGATAGGGGA CAGCGTTAGG 
AAGAAGCACG AGCCCAAAGT GAATAATGTC ACTGGGAACT TCACATTTGT CCTTAGAGAC 
TTACTTCCAA AGACAAACTA CTGTGTATCT CTTTATTTTG ATGATGACCC CGCAATAAAA 
TCTCCCTTAA AATGCATCGT CCTTCAGCCT GGCCAGGAAT CAGGATTATC AGAATCTGCT 
ATAGTAGGAA TAACTACTTC GTGTTTGGTA GTGATGGTTT TCGTGAGCAC TATCGTAATG 
CTGAAACGGA TTGGTTATAT ATGCCTAAAA GACAATTTGC CCAATGTCTT GAACTTCCGC 
CACTTTTTAA CCTGGATAAT CCCTGAACGG TCACCTTCAG AAGCCATCGA TCGGCTGGAA 
ATCATCCCCA CAAACAAGAA GAAGAGACTG TGGAATTACG ATTATGAGGA TGGCAGTGAC 
AGTGACGAAG AGGTCCCCAC AGCAAGTGTC ACTGGCTACA CCATGCATGG ACTGACGGGC 
AAGCCTCTGC AACAAACCTC TGACACCTCA GCCAGCCCCG AGGATCCCCT GCATGAAGAA 
GATTCAGGCG CTGAGGAATC TGATGAAGCT GGAGCAGGGG CTGGAGCTGA GCCAGAACTC 
CCCACAGAGG CGGGGGCGGG GCCTTCAGAA GACCCCACTG GCCCCTATGA GAGAAGAAAG 
AGTGTGCTCG AGGACTCATT CCCCAGGGAG GACAACAGCT CCATGGATGA GCCTGGGGAC 
AACATTATCT TCAACGTGAA CTTAAACTCT GTGTTTCTGA GGGTTCTCCA TGATGAAGAT 
GCCTCAGAGA CATTATCTCT CGAAGAAGAC ACCATCCTCC TAGACGAAGG TCCCCAGAGG 
ACAGAGTCAG ACCTTCGGAT AGCTGGTGGG GACAGGACAC AGCCGCCCCT CCCCAGCCTT 
CCTTCCCAGG ATCTATGGAC TGAAGATGGG TCATCTGAGA AATCAGACAC CTCAGATTCC 
GATGCTGATG TGGGGGACGG CTACATCATG AGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011244402.1
CDS509..1744
Translation

Target ORF information:

RefSeq Version XM_011246100.2
Organism Mus musculus(house mouse)
Definition Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011246100.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAGAGCT ACGTCGTCGC CATCGTCATA GTGCACAGAG GGGACTTGAC CGTGTGCCGC 
TGCTCAGACT ACATCGTGCC TGCAAACGCT CCTCTTGAGC CGCCAGAATT TGAGATCGTT 
GGCTTTACAG ACCACATAAA CGTGACGATG GAATTTCCAC CTGTCACTTC CAAAATAATC 
CAGGAAAAGA TGAAGACTAC ACCCTTTGTC ATCAAAGAAC AGATAGGGGA CAGCGTTAGG 
AAGAAGCACG AGCCCAAAGT GAATAATGTC ACTGGGAACT TCACATTTGT CCTTAGAGAC 
TTACTTCCAA AGACAAACTA CTGTGTATCT CTTTATTTTG ATGATGACCC CGCAATAAAA 
TCTCCCTTAA AATGCATCGT CCTTCAGCCT GGCCAGGAAT CAGGATTATC AGAATCTGCT 
ATAGTAGGAA TAACTACTTC GTGTTTGGTA GTGATGGTTT TCGTGAGCAC TATCGTAATG 
CTGAAACGGA TTGGTTATAT ATGCCTAAAA GACAATTTGC CCAATGTCTT GAACTTCCGC 
CACTTTTTAA CCTGGATAAT CCCTGAACGG TCACCTTCAG AAGCCATCGA TCGGCTGGAA 
ATCATCCCCA CAAACAAGAA GAAGAGACTG TGGAATTACG ATTATGAGGA TGGCAGTGAC 
AGTGACGAAG AGGTCCCCAC AGCAAGTGTC ACTGGCTACA CCATGCATGG ACTGACGGGC 
AAGCCTCTGC AACAAACCTC TGACACCTCA GCCAGCCCCG AGGATCCCCT GCATGAAGAA 
GATTCAGGCG CTGAGGAATC TGATGAAGCT GGAGCAGGGG CTGGAGCTGA GCCAGAACTC 
CCCACAGAGG CGGGGGCGGG GCCTTCAGAA GACCCCACTG GCCCCTATGA GAGAAGAAAG 
AGTGTGCTCG AGGACTCATT CCCCAGGGAG GACAACAGCT CCATGGATGA GCCTGGGGAC 
AACATTATCT TCAACGTGAA CTTAAACTCT GTGTTTCTGA GGGTTCTCCA TGATGAAGAT 
GCCTCAGAGA CATTATCTCT CGAAGAAGAC ACCATCCTCC TAGACGAAGG TCCCCAGAGG 
ACAGAGTCAG ACCTTCGGAT AGCTGGTGGG GACAGGACAC AGCCGCCCCT CCCCAGCCTT 
CCTTCCCAGG ATCTATGGAC TGAAGATGGG TCATCTGAGA AATCAGACAC CTCAGATTCC 
GATGCTGATG TGGGGGACGG CTACATCATG AGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu52677
Clone ID Related Accession (Same CDS sequence) NM_001347258.1
Accession Version NM_001347258.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-07
Organism Mus musculus(house mouse)
Product interferon alpha/beta receptor 2 isoform c precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC152503.5. On Nov 19, 2016 this sequence version replaced XM_006522923.3. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (c) is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y09864.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCGTTCAC GGTGCACCGT CTCTGCCGTC GGTCTCCTCA GCTTGTGTCT TGTGGTGTCT 
GCGAGCCTAG AGACTATCAC ACCGTCTGCT TTTGATGGGT ATCCAGATGA ACCTTGCACT 
ATAAACATAA CAATACGAAA TTCCCGGCTA ATTTTATCCT GGGAATTAGA GAACAAGTCT 
GGCCCACCCG CTAACTACAC CCTCTGGTAC ACAGTCATGA GCAAAGACGA AAATCTGACG 
AAGGTTAAGA ACTGTTCAGA TACCACGAAG TCATCATGTG ACGTGACAGA TAAGTGGTTG 
GAGGGCATGG AGAGCTACGT CGTCGCCATC GTCATAGTGC ACAGAGGGGA CTTGACCGTG 
TGCCGCTGCT CAGACTACAT CGTGCCTGCA AACGCTCCTC TTGAGCCGCC AGAATTTGAG 
ATCGTTGGCT TTACAGACCA CATAAACGTG ACGATGGAAT TTCCACCTGT CACTTCCAAA 
ATAATCCAGG AAAAGATGAA GACTACACCC TTTGTCATCA AAGAACAGAT AGGGGACAGC 
GTTAGGAAGA AGCACGAGCC CAAAGTGAAT AATGTCACTG GGAACTTCAC ATTTGTCCTT 
AGAGACTTAC TTCCAAAGAC AAACTACTGT GTATCTCTTT ATTTTGATGA TGACCCCGCA 
ATAAAATCTC CCTTAAAATG CATCGTCCTT CAGCCTGGCC AGGAATCAGA ACTTCCGCCA 
CTTTTTAACC TGGATAATCC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001334187.1
CDS331..1074
Translation

Target ORF information:

RefSeq Version NM_001347258.1
Organism Mus musculus(house mouse)
Definition Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001347258.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCGTTCAC GGTGCACCGT CTCTGCCGTC GGTCTCCTCA GCTTGTGTCT TGTGGTGTCT 
GCGAGCCTAG AGACTATCAC ACCGTCTGCT TTTGATGGGT ATCCAGATGA ACCTTGCACT 
ATAAACATAA CAATACGAAA TTCCCGGCTA ATTTTATCCT GGGAATTAGA GAACAAGTCT 
GGCCCACCCG CTAACTACAC CCTCTGGTAC ACAGTCATGA GCAAAGACGA AAATCTGACG 
AAGGTTAAGA ACTGTTCAGA TACCACGAAG TCATCATGTG ACGTGACAGA TAAGTGGTTG 
GAGGGCATGG AGAGCTACGT CGTCGCCATC GTCATAGTGC ACAGAGGGGA CTTGACCGTG 
TGCCGCTGCT CAGACTACAT CGTGCCTGCA AACGCTCCTC TTGAGCCGCC AGAATTTGAG 
ATCGTTGGCT TTACAGACCA CATAAACGTG ACGATGGAAT TTCCACCTGT CACTTCCAAA 
ATAATCCAGG AAAAGATGAA GACTACACCC TTTGTCATCA AAGAACAGAT AGGGGACAGC 
GTTAGGAAGA AGCACGAGCC CAAAGTGAAT AATGTCACTG GGAACTTCAC ATTTGTCCTT 
AGAGACTTAC TTCCAAAGAC AAACTACTGT GTATCTCTTT ATTTTGATGA TGACCCCGCA 
ATAAAATCTC CCTTAAAATG CATCGTCCTT CAGCCTGGCC AGGAATCAGA ACTTCCGCCA 
CTTTTTAACC TGGATAATCC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu79270
Clone ID Related Accession (Same CDS sequence) XM_017316882.1
Accession Version XM_017316882.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 783bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product interferon alpha/beta receptor 2 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGTTTTCG TGAGCACTAT CGTAATGCTG AAACGGATTG GTTATATATG CCTAAAAGAC 
AATTTGCCCA ATGTCTTGAA CTTCCGCCAC TTTTTAACCT GGATAATCCC TGAACGGTCA 
CCTTCAGAAG CCATCGATCG GCTGGAAATC ATCCCCACAA ACAAGAAGAA GAGACTGTGG 
AATTACGATT ATGAGGATGG CAGTGACAGT GACGAAGAGG TCCCCACAGC AAGTGTCACT 
GGCTACACCA TGCATGGACT GACGGGCAAG CCTCTGCAAC AAACCTCTGA CACCTCAGCC 
AGCCCCGAGG ATCCCCTGCA TGAAGAAGAT TCAGGCGCTG AGGAATCTGA TGAAGCTGGA 
GCAGGGGCTG GAGCTGAGCC AGAACTCCCC ACAGAGGCGG GGGCGGGGCC TTCAGAAGAC 
CCCACTGGCC CCTATGAGAG AAGAAAGAGT GTGCTCGAGG ACTCATTCCC CAGGGAGGAC 
AACAGCTCCA TGGATGAGCC TGGGGACAAC ATTATCTTCA ACGTGAACTT AAACTCTGTG 
TTTCTGAGGG TTCTCCATGA TGAAGATGCC TCAGAGACAT TATCTCTCGA AGAAGACACC 
ATCCTCCTAG ACGAAGGTCC CCAGAGGACA GAGTCAGACC TTCGGATAGC TGGTGGGGAC 
AGGACACAGC CGCCCCTCCC CAGCCTTCCT TCCCAGGATC TATGGACTGA AGATGGGTCA 
TCTGAGAAAT CAGACACCTC AGATTCCGAT GCTGATGTGG GGGACGGCTA CATCATGAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017172371.1
CDS1157..1939
Translation

Target ORF information:

RefSeq Version XM_017316882.1
Organism Mus musculus(house mouse)
Definition Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017316882.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGTTTTCG TGAGCACTAT CGTAATGCTG AAACGGATTG GTTATATATG CCTAAAAGAC 
AATTTGCCCA ATGTCTTGAA CTTCCGCCAC TTTTTAACCT GGATAATCCC TGAACGGTCA 
CCTTCAGAAG CCATCGATCG GCTGGAAATC ATCCCCACAA ACAAGAAGAA GAGACTGTGG 
AATTACGATT ATGAGGATGG CAGTGACAGT GACGAAGAGG TCCCCACAGC AAGTGTCACT 
GGCTACACCA TGCATGGACT GACGGGCAAG CCTCTGCAAC AAACCTCTGA CACCTCAGCC 
AGCCCCGAGG ATCCCCTGCA TGAAGAAGAT TCAGGCGCTG AGGAATCTGA TGAAGCTGGA 
GCAGGGGCTG GAGCTGAGCC AGAACTCCCC ACAGAGGCGG GGGCGGGGCC TTCAGAAGAC 
CCCACTGGCC CCTATGAGAG AAGAAAGAGT GTGCTCGAGG ACTCATTCCC CAGGGAGGAC 
AACAGCTCCA TGGATGAGCC TGGGGACAAC ATTATCTTCA ACGTGAACTT AAACTCTGTG 
TTTCTGAGGG TTCTCCATGA TGAAGATGCC TCAGAGACAT TATCTCTCGA AGAAGACACC 
ATCCTCCTAG ACGAAGGTCC CCAGAGGACA GAGTCAGACC TTCGGATAGC TGGTGGGGAC 
AGGACACAGC CGCCCCTCCC CAGCCTTCCT TCCCAGGATC TATGGACTGA AGATGGGTCA 
TCTGAGAAAT CAGACACCTC AGATTCCGAT GCTGATGTGG GGGACGGCTA CATCATGAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu67987
Clone ID Related Accession (Same CDS sequence) XM_011246100.2 , XM_011246100.3
Accession Version XM_011246100.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1236bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product interferon alpha/beta receptor 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011246100.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAGAGCT ACGTCGTCGC CATCGTCATA GTGCACAGAG GGGACTTGAC CGTGTGCCGC 
TGCTCAGACT ACATCGTGCC TGCAAACGCT CCTCTTGAGC CGCCAGAATT TGAGATCGTT 
GGCTTTACAG ACCACATAAA CGTGACGATG GAATTTCCAC CTGTCACTTC CAAAATAATC 
CAGGAAAAGA TGAAGACTAC ACCCTTTGTC ATCAAAGAAC AGATAGGGGA CAGCGTTAGG 
AAGAAGCACG AGCCCAAAGT GAATAATGTC ACTGGGAACT TCACATTTGT CCTTAGAGAC 
TTACTTCCAA AGACAAACTA CTGTGTATCT CTTTATTTTG ATGATGACCC CGCAATAAAA 
TCTCCCTTAA AATGCATCGT CCTTCAGCCT GGCCAGGAAT CAGGATTATC AGAATCTGCT 
ATAGTAGGAA TAACTACTTC GTGTTTGGTA GTGATGGTTT TCGTGAGCAC TATCGTAATG 
CTGAAACGGA TTGGTTATAT ATGCCTAAAA GACAATTTGC CCAATGTCTT GAACTTCCGC 
CACTTTTTAA CCTGGATAAT CCCTGAACGG TCACCTTCAG AAGCCATCGA TCGGCTGGAA 
ATCATCCCCA CAAACAAGAA GAAGAGACTG TGGAATTACG ATTATGAGGA TGGCAGTGAC 
AGTGACGAAG AGGTCCCCAC AGCAAGTGTC ACTGGCTACA CCATGCATGG ACTGACGGGC 
AAGCCTCTGC AACAAACCTC TGACACCTCA GCCAGCCCCG AGGATCCCCT GCATGAAGAA 
GATTCAGGCG CTGAGGAATC TGATGAAGCT GGAGCAGGGG CTGGAGCTGA GCCAGAACTC 
CCCACAGAGG CGGGGGCGGG GCCTTCAGAA GACCCCACTG GCCCCTATGA GAGAAGAAAG 
AGTGTGCTCG AGGACTCATT CCCCAGGGAG GACAACAGCT CCATGGATGA GCCTGGGGAC 
AACATTATCT TCAACGTGAA CTTAAACTCT GTGTTTCTGA GGGTTCTCCA TGATGAAGAT 
GCCTCAGAGA CATTATCTCT CGAAGAAGAC ACCATCCTCC TAGACGAAGG TCCCCAGAGG 
ACAGAGTCAG ACCTTCGGAT AGCTGGTGGG GACAGGACAC AGCCGCCCCT CCCCAGCCTT 
CCTTCCCAGG ATCTATGGAC TGAAGATGGG TCATCTGAGA AATCAGACAC CTCAGATTCC 
GATGCTGATG TGGGGGACGG CTACATCATG AGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011244402.1
CDS502..1737
Translation

Target ORF information:

RefSeq Version XM_011246100.3
Organism Mus musculus(house mouse)
Definition Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011246100.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAGAGCT ACGTCGTCGC CATCGTCATA GTGCACAGAG GGGACTTGAC CGTGTGCCGC 
TGCTCAGACT ACATCGTGCC TGCAAACGCT CCTCTTGAGC CGCCAGAATT TGAGATCGTT 
GGCTTTACAG ACCACATAAA CGTGACGATG GAATTTCCAC CTGTCACTTC CAAAATAATC 
CAGGAAAAGA TGAAGACTAC ACCCTTTGTC ATCAAAGAAC AGATAGGGGA CAGCGTTAGG 
AAGAAGCACG AGCCCAAAGT GAATAATGTC ACTGGGAACT TCACATTTGT CCTTAGAGAC 
TTACTTCCAA AGACAAACTA CTGTGTATCT CTTTATTTTG ATGATGACCC CGCAATAAAA 
TCTCCCTTAA AATGCATCGT CCTTCAGCCT GGCCAGGAAT CAGGATTATC AGAATCTGCT 
ATAGTAGGAA TAACTACTTC GTGTTTGGTA GTGATGGTTT TCGTGAGCAC TATCGTAATG 
CTGAAACGGA TTGGTTATAT ATGCCTAAAA GACAATTTGC CCAATGTCTT GAACTTCCGC 
CACTTTTTAA CCTGGATAAT CCCTGAACGG TCACCTTCAG AAGCCATCGA TCGGCTGGAA 
ATCATCCCCA CAAACAAGAA GAAGAGACTG TGGAATTACG ATTATGAGGA TGGCAGTGAC 
AGTGACGAAG AGGTCCCCAC AGCAAGTGTC ACTGGCTACA CCATGCATGG ACTGACGGGC 
AAGCCTCTGC AACAAACCTC TGACACCTCA GCCAGCCCCG AGGATCCCCT GCATGAAGAA 
GATTCAGGCG CTGAGGAATC TGATGAAGCT GGAGCAGGGG CTGGAGCTGA GCCAGAACTC 
CCCACAGAGG CGGGGGCGGG GCCTTCAGAA GACCCCACTG GCCCCTATGA GAGAAGAAAG 
AGTGTGCTCG AGGACTCATT CCCCAGGGAG GACAACAGCT CCATGGATGA GCCTGGGGAC 
AACATTATCT TCAACGTGAA CTTAAACTCT GTGTTTCTGA GGGTTCTCCA TGATGAAGAT 
GCCTCAGAGA CATTATCTCT CGAAGAAGAC ACCATCCTCC TAGACGAAGG TCCCCAGAGG 
ACAGAGTCAG ACCTTCGGAT AGCTGGTGGG GACAGGACAC AGCCGCCCCT CCCCAGCCTT 
CCTTCCCAGG ATCTATGGAC TGAAGATGGG TCATCTGAGA AATCAGACAC CTCAGATTCC 
GATGCTGATG TGGGGGACGG CTACATCATG AGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu22267
Clone ID Related Accession (Same CDS sequence) NM_010509.2
Accession Version NM_010509.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1542bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-26
Organism Mus musculus(house mouse)
Product interferon alpha/beta receptor 2 isoform a precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX515017.1, AK139169.1, AK153317.1, AV351897.1, AC152503.5 and BE691178.1. On Nov 16, 2007 this sequence version replaced NM_010509.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK150386.1, AK153317.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCGTTCAC GGTGCACCGT CTCTGCCGTC GGTCTCCTCA GCTTGTGTCT TGTGGTGTCT 
GCGAGCCTAG AGACTATCAC ACCGTCTGCT TTTGATGGGT ATCCAGATGA ACCTTGCACT 
ATAAACATAA CAATACGAAA TTCCCGGCTA ATTTTATCCT GGGAATTAGA GAACAAGTCT 
GGCCCACCCG CTAACTACAC CCTCTGGTAC ACAGTCATGA GCAAAGACGA AAATCTGACG 
AAGGTTAAGA ACTGTTCAGA TACCACGAAG TCATCATGTG ACGTGACAGA TAAGTGGTTG 
GAGGGCATGG AGAGCTACGT CGTCGCCATC GTCATAGTGC ACAGAGGGGA CTTGACCGTG 
TGCCGCTGCT CAGACTACAT CGTGCCTGCA AACGCTCCTC TTGAGCCGCC AGAATTTGAG 
ATCGTTGGCT TTACAGACCA CATAAACGTG ACGATGGAAT TTCCACCTGT CACTTCCAAA 
ATAATCCAGG AAAAGATGAA GACTACACCC TTTGTCATCA AAGAACAGAT AGGGGACAGC 
GTTAGGAAGA AGCACGAGCC CAAAGTGAAT AATGTCACTG GGAACTTCAC ATTTGTCCTT 
AGAGACTTAC TTCCAAAGAC AAACTACTGT GTATCTCTTT ATTTTGATGA TGACCCCGCA 
ATAAAATCTC CCTTAAAATG CATCGTCCTT CAGCCTGGCC AGGAATCAGG ATTATCAGAA 
TCTGCTATAG TAGGAATAAC TACTTCGTGT TTGGTAGTGA TGGTTTTCGT GAGCACTATC 
GTAATGCTGA AACGGATTGG TTATATATGC CTAAAAGACA ATTTGCCCAA TGTCTTGAAC 
TTCCGCCACT TTTTAACCTG GATAATCCCT GAACGGTCAC CTTCAGAAGC CATCGATCGG 
CTGGAAATCA TCCCCACAAA CAAGAAGAAG AGACTGTGGA ATTACGATTA TGAGGATGGC 
AGTGACAGTG ACGAAGAGGT CCCCACAGCA AGTGTCACTG GCTACACCAT GCATGGACTG 
ACGGGCAAGC CTCTGCAACA AACCTCTGAC ACCTCAGCCA GCCCCGAGGA TCCCCTGCAT 
GAAGAAGATT CAGGCGCTGA GGAATCTGAT GAAGCTGGAG CAGGGGCTGG AGCTGAGCCA 
GAACTCCCCA CAGAGGCGGG GGCGGGGCCT TCAGAAGACC CCACTGGCCC CTATGAGAGA 
AGAAAGAGTG TGCTCGAGGA CTCATTCCCC AGGGAGGACA ACAGCTCCAT GGATGAGCCT 
GGGGACAACA TTATCTTCAA CGTGAACTTA AACTCTGTGT TTCTGAGGGT TCTCCATGAT 
GAAGATGCCT CAGAGACATT ATCTCTCGAA GAAGACACCA TCCTCCTAGA CGAAGGTCCC 
CAGAGGACAG AGTCAGACCT TCGGATAGCT GGTGGGGACA GGACACAGCC GCCCCTCCCC 
AGCCTTCCTT CCCAGGATCT ATGGACTGAA GATGGGTCAT CTGAGAAATC AGACACCTCA 
GATTCCGATG CTGATGTGGG GGACGGCTAC ATCATGAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_034639.2
CDS331..1872
Translation

Target ORF information:

RefSeq Version NM_010509.2
Organism Mus musculus(house mouse)
Definition Mus musculus interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_010509.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCGTTCAC GGTGCACCGT CTCTGCCGTC GGTCTCCTCA GCTTGTGTCT TGTGGTGTCT 
GCGAGCCTAG AGACTATCAC ACCGTCTGCT TTTGATGGGT ATCCAGATGA ACCTTGCACT 
ATAAACATAA CAATACGAAA TTCCCGGCTA ATTTTATCCT GGGAATTAGA GAACAAGTCT 
GGCCCACCCG CTAACTACAC CCTCTGGTAC ACAGTCATGA GCAAAGACGA AAATCTGACG 
AAGGTTAAGA ACTGTTCAGA TACCACGAAG TCATCATGTG ACGTGACAGA TAAGTGGTTG 
GAGGGCATGG AGAGCTACGT CGTCGCCATC GTCATAGTGC ACAGAGGGGA CTTGACCGTG 
TGCCGCTGCT CAGACTACAT CGTGCCTGCA AACGCTCCTC TTGAGCCGCC AGAATTTGAG 
ATCGTTGGCT TTACAGACCA CATAAACGTG ACGATGGAAT TTCCACCTGT CACTTCCAAA 
ATAATCCAGG AAAAGATGAA GACTACACCC TTTGTCATCA AAGAACAGAT AGGGGACAGC 
GTTAGGAAGA AGCACGAGCC CAAAGTGAAT AATGTCACTG GGAACTTCAC ATTTGTCCTT 
AGAGACTTAC TTCCAAAGAC AAACTACTGT GTATCTCTTT ATTTTGATGA TGACCCCGCA 
ATAAAATCTC CCTTAAAATG CATCGTCCTT CAGCCTGGCC AGGAATCAGG ATTATCAGAA 
TCTGCTATAG TAGGAATAAC TACTTCGTGT TTGGTAGTGA TGGTTTTCGT GAGCACTATC 
GTAATGCTGA AACGGATTGG TTATATATGC CTAAAAGACA ATTTGCCCAA TGTCTTGAAC 
TTCCGCCACT TTTTAACCTG GATAATCCCT GAACGGTCAC CTTCAGAAGC CATCGATCGG 
CTGGAAATCA TCCCCACAAA CAAGAAGAAG AGACTGTGGA ATTACGATTA TGAGGATGGC 
AGTGACAGTG ACGAAGAGGT CCCCACAGCA AGTGTCACTG GCTACACCAT GCATGGACTG 
ACGGGCAAGC CTCTGCAACA AACCTCTGAC ACCTCAGCCA GCCCCGAGGA TCCCCTGCAT 
GAAGAAGATT CAGGCGCTGA GGAATCTGAT GAAGCTGGAG CAGGGGCTGG AGCTGAGCCA 
GAACTCCCCA CAGAGGCGGG GGCGGGGCCT TCAGAAGACC CCACTGGCCC CTATGAGAGA 
AGAAAGAGTG TGCTCGAGGA CTCATTCCCC AGGGAGGACA ACAGCTCCAT GGATGAGCCT 
GGGGACAACA TTATCTTCAA CGTGAACTTA AACTCTGTGT TTCTGAGGGT TCTCCATGAT 
GAAGATGCCT CAGAGACATT ATCTCTCGAA GAAGACACCA TCCTCCTAGA CGAAGGTCCC 
CAGAGGACAG AGTCAGACCT TCGGATAGCT GGTGGGGACA GGACACAGCC GCCCCTCCCC 
AGCCTTCCTT CCCAGGATCT ATGGACTGAA GATGGGTCAT CTGAGAAATC AGACACCTCA 
GATTCCGATG CTGATGTGGG GGACGGCTAC ATCATGAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1?.
Journal of immunology (Baltimore, Md. : 1950)198(11)4210-4215(2017 Jun)
Zhu Q,Kanneganti TD