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ABCC1 cDNA ORF clone, Mus musculus(House mouse)

Gene Symbol ABCC1
Entrez Gene ID 17250
Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Synonyms Abcc1a,Abcc1b,MRP,Mdrap,Mrp1
General protein information
Preferred Names

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Names

multidrug resistance-associated protein 1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1a
ATP-binding cassette, sub-family C (CFTR/MRP), member 1b
LTC4 transporter
leukotriene C(4) transporter
multiple drug resistance-associated protein

Gene Type protein-coding
Organism Mus musculus(House mouse)
Genome

16

16|16 A1

Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. The encoded protein may also play an essential role in steroid hormone homeostasis as a transporter for steroid hormones and their metabolites. [provided by RefSeq, Nov 2011].

mRNA and Protein(s)

mRNA Protein Name
NM_008576.3 NP_032602.1 multidrug resistance-associated protein 1
XM_017316888.1 XP_017172377.1 multidrug resistance-associated protein 1 isoform X2
XM_006521839.3 XP_006521902.2 multidrug resistance-associated protein 1 isoform X1



Danio rerio (zebrafish) abcc1 XP_001341895.3
Caenorhabditis elegans (roundworm) mrp-1 NP_001033553.1
Arabidopsis thaliana (thale cress) MRP5 NP_171908.1
Oryza sativa (rice) Os03g0142800 NP_001048934.1
Canis lupus familiaris (dog) ABCC1 NP_001002971.1
Bos taurus (cattle) ABCC1 NP_776648.1
Homo sapiens (human) ABCC1 NP_004987.2
Pan troglodytes (chimpanzee) ABCC1 XP_001145351.1
Rattus norvegicus (Norway rat) Abcc1 NP_071617.2
Gallus gallus (chicken) ABCC1 NP_001012540.1
Mus musculus (house mouse) Abcc1 NP_032602.1
Caenorhabditis elegans (roundworm) mrp-2 NP_508121.1


Related articles in PubMed

Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.
Steinmetz CC, Tatavarty V, Sugino K, Shima Y, Joseph A, Lin H, Rutlin M, Lambo M, Hempel CM, Okaty BW, Paradis S, Nelson SB, Turrigiano GG
Cell reports16(10)2711-22(2016 Sep)

Multidrug resistance associated protein-1 (MRP1) deficiency attenuates endothelial dysfunction in diabetes.
Neuser J, Fraccarollo D, Wick M, Bauersachs J, Widder JD
Journal of diabetes and its complications30(4)623-7(2016 May-Jun)

Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells.
Gordillo GM, Biswas A, Khanna S, Spieldenner JM, Pan X, Sen CK
The Journal of biological chemistry291(19)10089-103(2016 May)

Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier.
Chapy H, Saubaméa B, Tournier N, Bourasset F, Behar-Cohen F, Declèves X, Scherrmann JM, Cisternino S
British journal of pharmacology173(3)497-510(2016 Feb)

Maternal bile acid transporter deficiency promotes neonatal demise.
Zhang Y, Li F, Wang Y, Pitre A, Fang ZZ, Frank MW, Calabrese C, Krausz KW, Neale G, Frase S, Vogel P, Rock CO, Gonzalez FJ, Schuetz JD
Nature communications68186(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data, including data from studies in knockout mice, suggest that Mrp1 is involved in development of vascular endothelial dysfunction in diabetic angiopathy; Mrp1 appears to be required for oxidative stress in endothelial cells due to hyperglycemia.
Title: Multidrug resistance associated protein-1 (MRP1) deficiency attenuates endothelial dysfunction in diabetes.

Oxidant-enriched Tumorigenic Endothelial Cells (EOMA) cells survive a heavy oxidant burden by rapid efflux of GSSG, which is lethal if trapped within the cell. A hyperactive MRP-1 system for GSSG efflux acts as a critical survival factor for these cells, making it a potential target for EOMA therapeutics.
Title: Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells.

P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier
Title: Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier.

neprilysin x ABCC1 double-deficient mice present a new model for early effects of amyloid-beta-related mild cognitive impairment that allows investigations without artificial overexpression of inherited Alzheimer's disease genes
Title: Accumulation of murine amyloid-β mimics early Alzheimer's disease.

Lentivirus-based RNAi stably knocks down the expression of the Mrp1 gene in the established TM4 sertoli cell line.
Title: Establishment of stable MRP1 knockdown by lentivirus-delivered shRNA in the mouse testis Sertoli TM4 cell line.

The following ABCC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OMu15679 NM_008576.3
Latest version!
Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$639.50-$895.30
$1279.00
OMu79272 XM_017316888.1
Latest version!
Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 14-16 $391.30
$559.00
OMu68194 XM_006521839.3
Latest version!
Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 25 $811.30
$1159.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OMu15679
Clone ID Related Accession (Same CDS sequence) NM_008576.3
Accession Version NM_008576.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 4587bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Mus musculus(House mouse)
Product multidrug resistance-associated protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK029876.1, BC090617.1 and BP762240.1. On Nov 17, 2011 this sequence version replaced NM_008576.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK029876.1, BC090617.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
ATGGCGCTGC GCAGCTTCTG CAGCGCTGAT GGCTCCGATC CACTCTGGGA CTGGAATGTC 
ACATGGCACA CCAGCAACCC CGACTTTACC AAGTGCTTTC AGAACACGGT CCTCACATGG
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCTTCTATCT CTCTCGCCAT
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAACCA AAACTGCCTT AGGATTCTTT
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAGTG
CTCCGAGCCC CAGTGTTACT GGTCAGCCCA ACACTGCTGG GCATCACCAT GCTGCTCGCC
ACCTTTTTGA TACAGCTTGA ACGGAGGAAG GGAGTCCAAT CCTCGGGAAT TATGCTTACT
TTCTGGCTCG TAGCCCTACT CTGTGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC
TTAAAAAAGG ATGCTCATGT GGACGTGTTT CGAGATTCCA CGTTCTATCT GTACTTCACC
CTTGTGCTTG TTCAGCTCGT GCTGTCCTGC TTCTCAGACT GCTCACCCCT GTTCTCTGAA
ACTGTCCATG ACCGGAATCC ATGCCCAGAA TCCAGTGCCT CTTTCCTTTC CAGGATTACT
TTCTGGTGGA TTACAGGGAT GATGGTGCAC GGCTACCGCC AGCCCCTGGA GAGCAGTGAC
CTCTGGTCAT TGAATAAGGA GGACACATCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC
TGGAAGAAGG AATGTGATAA GTCAAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC
AAAGATCCCA GCAAGCCTAA GGGAAGTTCC CAGTTGGATG TGAATGAGGA GGTGGAGGCA
CTGATTGTCA AGTCACCCCA CAAGGATCGG GAGCCCTCTC TGTTCAAGGT GTTATACAAG
ACTTTTGGTC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG
TTTGCCGGCC CCAAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCTCCC
GACTGGCAGG GCTACTTTTA CACAGCACTG CTGTTTGTCA GCGCCTGTCT GCAGACACTG
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCAGTGGCA TGCGCATCAA GACTGCTGTG
GTGGGCGCTG TCTATCGTAA GGCTCTTTTG ATCACCAATG CAGCTAGAAA ATCTTCCACG
GTCGGAGAGA TTGTCAACCT CATGTCCGTG GATGCTCAGC GCTTCATGGA CTTGGCCACG
TACATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCATCC TAGCCCTCTA CTTCCTGTGG
CTGAGCCTGG GCCCTTCTGT GCTGGCTGGA GTGGCTGTGA TGATTCTCAT GGTACCCTTA
AATGCTGTGA TGGCCATGAA GACCAAGACC TACCAGGTGG CACACATGAA GAGCAAAGAC
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTCCTCAA GCTGTACGCC
TGGGAGCTGG CCTTCCAGGA CAAAGTCATG AGCATCAGGC AGGAGGAGCT CAAGGTGCTG
AAGAAATCTG CCTACTTGGC AGCTGTAGGC ACATTCACGT GGGTGTGCAC ACCTTTCCTG
GTGGCCCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGATG AGAGAAATAT CCTAGATGCA
AAGAAAGCCT TTGTGTCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTG
CCCATGGTTA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATTTTT
CTGTCTCATG AGGAGCTGGA GCCAGACAGC ATTGAGCGGA GGTCGATCAA GAGTGGCGAA
GGGAATAGCA TCACTGTGAA GAATGCAACC TTCACTTGGG CCAGGGGTGA ACCTCCCACA
CTGAATGGCA TCACCTTCTC CATTCCTGAA GGAGCCCTTG TGGCCGTGGT GGGCCAGGTA
GGCTGCGGGA AGTCATCTCT GCTGTCAGCC CTGCTGGCTG AGATGGACAA GGTGGAGGGA
CATGTGACTC TCAAGGGCTC CGTGGCCTAC GTGCCCCAGC AGGCCTGGAT TCAGAATGAC
TCTCTCCGAG AGAACATACT GTTTGGGCAC CCCCTGCAGG AAAATTACTA CAAGGCAGTT
ATGGAAGCCT GTGCCCTTCT TCCAGATTTG GAAATCCTGC CCAGTGGGGA CCGCACAGAG
ATCGGTGAGA AGGGTGTGAA CCTGTCAGGG GGCCAGAAGC AGCGTGTGAG CCTGGCCCGG
GCTGTGTACT CTAACTCTGA CATCTACCTC TTTGATGACC CCCTCTCGGC TGTGGATGCA
CATGTTGGGA AGCACATCTT TGAGAAGGTG GTTGGTCCCA TGGGCCTACT GAAGAACAAG
ACACGGATCC TGGTCACCCA TGGTATCAGC TACCTGCCCC AAGTGGATGT CATCATTGTC
ATGAGTGGCG GCAAGATCTC AGAGATGGGT TCTTATCAGG AGCTGCTAGA CCGGGATGGG
GCCTTCGCTG AGTTCCTGCG CACCTATGCC AACGCTGAGC AGGACCTGGC CTCGGAGGAT
GACAGTGTCA GTGGTTCAGG GAAGGAGTCA AAGCCGGTGG AAAATGGGAT GCTGGTGACA
GACACCGTAG GAAAGCACCT GCAGAGGCAT CTCAGCAACT CGTCTTCCCA CAGTGGGGAT
ACCAGCCAGC AACACAGCAG CATAGCCGAA CTGCAGAAGG CTGGAGCTAA GGAGGAGACG
TGGAAGCTAA TGGAAGCAGA CAAGGCCCAG ACAGGGCAGG TGCAGCTGTC AGTGTACTGG
AACTACATGA AGGCCATTGG CCTCTTCATC ACCTTCTTGA GTATCTTCCT TTTCCTGTGC
AACCATGTAT CTGCACTGGC CTCTAACTAT TGGCTGAGCC TCTGGACAGA TGACCCCCCT
GTTGTCAATG GGACTCAGGC GAACAGGAAT TTTCGGCTGA GTGTCTATGG GGCCTTGGGC
ATCTTGCAAG GTGCAGCAAT ATTTGGCTAC TCCATGGCTG TGTCCATCGG GGGCATCTTT
GCCTCCCGTC GCTTGCACCT GGACCTGCTA TACAATGTTC TGCGATCACC CATGAGTTTC
TTTGAGCGTA CACCCAGTGG GAACCTAGTG AACCGATTCT CCAAGGAGCT GGACACAGTG
GACTCCATGA TCCCGCAGGT CATCAAGATG TTCATGGGTT CACTCTTCAG TGTCATTGGA
GCTGTCATCA TCATCCTACT GGCCACGCCC ATTGCCGCAG TCATCATCCC ACCCTTGGGT
CTGGTTTACT TCTTTGTGCA GAGGTTCTAT GTGGCTTCCT CAAGACAACT GAAGCGCCTG
GAGTCTGTCA GCCGTTCCCC TGTGTACTCA CACTTCAATG AGACCTTGCT GGGAGTCAGT
GTCATCCGTG CTTTTGAGGA GCAGGAGCGC TTCATTCACC AGAGTGACCT GAAAGTAGAT
GAGAACCAGA AGGCCTACTA CCCCAGCATT GTGGCCAACA GGTGGCTTGC TGTGCGCCTT
GAGTGTGTGG GCAACTGCAT TGTGCTGTTT GCTGCCCTCT TTGCAGTCAT CTCCCGGCAC
AGCCTCAGTG CTGGCTTGGT GGGCCTCTCT GTGTCTTACT CACTGCAGAT AACTGCATAC
TTGAACTGGC TGGTTCGAAT GTCCTCGGAG ATGGAGACCA ACATTGTGGC AGTGGAGAGA
CTGAAGGAGT ATTCTGAAAC AGAGAAGGAG GCTCCTTGGC AAATCCAGGA AACAGCTCCA
CCCAGCACCT GGCCCCATTC AGGCCGTGTA GAGTTCCGGG ATTACTGCCT GAGGTATCGA
GAAGACTTGG ACTTGGTTCT CAAGCACATA AATGTCACCA TTGAGGGTGG AGAAAAGGTG
GGTATTGTAG GTCGTACGGG AGCTGGGAAA TCATCTCTCA CCCTGGGTTT GTTCCGGATC
AATGAGTCTG CAGAAGGGGA GATCATCATT GATGGGGTCA ACATCGCCAA GATCGGCCTG
CACAACCTGC GCTTCAAGAT CACCATCATT CCACAGGATC CTGTTTTGTT CTCGGGTTCC
CTCCGCATGA ACTTGGACCC TTTCAGTCAG TATTCTGATG AAGAAGTCTG GATGGCCCTG
GAGCTTGCTC ACCTAAAGGG CTTTGTGTCA GCTTTGCCTG ACAAGCTGAA CCATGAGTGT
GCAGAAGGTG GAGAGAACCT GAGTGTGGGG CAGCGACAGC TTGTGTGCCT GGCCCGGGCT
CTGCTGAGGA AGACAAAGAT TCTAGTGTTG GACGAGGCTA CCGCAGCTGT GGACCTAGAG
ACAGATAACC TTATCCAGTC CACCATCCGG ACACAGTTTG AAGACTGTAC TGTGCTCACG
ATTGCTCATC GGCTTAACAC CATAATGGAC TACACGCGGG TGATTGTCCT GGACAAAGGA
GAAGTTCGGG AGTGTGGTGC ACCCTCTGAG CTCCTGCAGC AAAGAGGCAT CTTCTACAGC
ATGGCCAAGG ATGCTGGCTT GGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_032602.1
CDS39..4625
Misc Feature(1)57..4619
Misc Feature(2)138..200
Misc Feature(3)261..323
Misc Feature(4)339..401
Misc Feature(5)438..500
Misc Feature(6)555..617
Misc Feature(7)867..869
Misc Feature(8)906..908
Misc Feature(9)990..1052
Misc Feature(10)1026..1829
Misc Feature(11)1131..1193
Misc Feature(12)1362..1424
Misc Feature(13)1434..1496
Misc Feature(14)1548..1550
Misc Feature(15)1683..1745
Misc Feature(16)1812..1874
Misc Feature(17)1968..2573
Misc Feature(18)2070..2093
Misc Feature(19)order(2079..2084,2088..2096,2175..2177,2412..2417,2517..2519)
Misc Feature(20)2166..2177
Misc Feature(21)2340..2369
Misc Feature(22)2400..2417
Misc Feature(23)2424..2435
Misc Feature(24)2505..2525
Misc Feature(25)2670..2672
Misc Feature(26)2682..2684
Misc Feature(27)2772..2774
Misc Feature(28)2817..2819
Misc Feature(29)2928..2990
Misc Feature(30)2961..3761
Misc Feature(31)3105..3167
Misc Feature(32)3297..3359
Misc Feature(33)3363..3425
Misc Feature(34)3639..3701
Misc Feature(35)3708..3770
Misc Feature(36)3900..4562
Exon (1)1..86
Exon (2)87..263
Exon (3)264..389
Exon (4)390..527
Exon (5)528..653
Exon (6)654..715
Exon (7)716..847
Exon (8)848..1081
Exon (9)1082..1259
Exon (10)1260..1421
Exon (11)1422..1514
Exon (12)1515..1718
Exon (13)1719..1865
Exon (14)1866..1953
Exon (15)1954..2026
Exon (16)2027..2153
Exon (17)2154..2330
Exon (18)2331..2498
Exon (19)2499..2682
Exon (20)2683..2764
Exon (21)2765..2897
Exon (22)2898..3108
Exon (23)3109..3419
Exon (24)3420..3619
Exon (25)3620..3746
Exon (26)3747..3848
Exon (27)3849..3995
Exon (28)3996..4154
Exon (29)4155..4321
Exon (30)4322..4516
Exon (31)4517..5935
Translation

Target ORF information:

RefSeq Version NM_008576.3
Organism Mus musculus(House mouse)
Definition Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_008576.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
ATGGCGCTGC GCAGCTTCTG CAGCGCTGAT GGCTCCGATC CACTCTGGGA CTGGAATGTC 
ACATGGCACA CCAGCAACCC CGACTTTACC AAGTGCTTTC AGAACACGGT CCTCACATGG
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCTTCTATCT CTCTCGCCAT
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAACCA AAACTGCCTT AGGATTCTTT
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAGTG
CTCCGAGCCC CAGTGTTACT GGTCAGCCCA ACACTGCTGG GCATCACCAT GCTGCTCGCC
ACCTTTTTGA TACAGCTTGA ACGGAGGAAG GGAGTCCAAT CCTCGGGAAT TATGCTTACT
TTCTGGCTCG TAGCCCTACT CTGTGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC
TTAAAAAAGG ATGCTCATGT GGACGTGTTT CGAGATTCCA CGTTCTATCT GTACTTCACC
CTTGTGCTTG TTCAGCTCGT GCTGTCCTGC TTCTCAGACT GCTCACCCCT GTTCTCTGAA
ACTGTCCATG ACCGGAATCC ATGCCCAGAA TCCAGTGCCT CTTTCCTTTC CAGGATTACT
TTCTGGTGGA TTACAGGGAT GATGGTGCAC GGCTACCGCC AGCCCCTGGA GAGCAGTGAC
CTCTGGTCAT TGAATAAGGA GGACACATCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC
TGGAAGAAGG AATGTGATAA GTCAAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC
AAAGATCCCA GCAAGCCTAA GGGAAGTTCC CAGTTGGATG TGAATGAGGA GGTGGAGGCA
CTGATTGTCA AGTCACCCCA CAAGGATCGG GAGCCCTCTC TGTTCAAGGT GTTATACAAG
ACTTTTGGTC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG
TTTGCCGGCC CCAAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCTCCC
GACTGGCAGG GCTACTTTTA CACAGCACTG CTGTTTGTCA GCGCCTGTCT GCAGACACTG
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCAGTGGCA TGCGCATCAA GACTGCTGTG
GTGGGCGCTG TCTATCGTAA GGCTCTTTTG ATCACCAATG CAGCTAGAAA ATCTTCCACG
GTCGGAGAGA TTGTCAACCT CATGTCCGTG GATGCTCAGC GCTTCATGGA CTTGGCCACG
TACATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCATCC TAGCCCTCTA CTTCCTGTGG
CTGAGCCTGG GCCCTTCTGT GCTGGCTGGA GTGGCTGTGA TGATTCTCAT GGTACCCTTA
AATGCTGTGA TGGCCATGAA GACCAAGACC TACCAGGTGG CACACATGAA GAGCAAAGAC
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTCCTCAA GCTGTACGCC
TGGGAGCTGG CCTTCCAGGA CAAAGTCATG AGCATCAGGC AGGAGGAGCT CAAGGTGCTG
AAGAAATCTG CCTACTTGGC AGCTGTAGGC ACATTCACGT GGGTGTGCAC ACCTTTCCTG
GTGGCCCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGATG AGAGAAATAT CCTAGATGCA
AAGAAAGCCT TTGTGTCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTG
CCCATGGTTA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATTTTT
CTGTCTCATG AGGAGCTGGA GCCAGACAGC ATTGAGCGGA GGTCGATCAA GAGTGGCGAA
GGGAATAGCA TCACTGTGAA GAATGCAACC TTCACTTGGG CCAGGGGTGA ACCTCCCACA
CTGAATGGCA TCACCTTCTC CATTCCTGAA GGAGCCCTTG TGGCCGTGGT GGGCCAGGTA
GGCTGCGGGA AGTCATCTCT GCTGTCAGCC CTGCTGGCTG AGATGGACAA GGTGGAGGGA
CATGTGACTC TCAAGGGCTC CGTGGCCTAC GTGCCCCAGC AGGCCTGGAT TCAGAATGAC
TCTCTCCGAG AGAACATACT GTTTGGGCAC CCCCTGCAGG AAAATTACTA CAAGGCAGTT
ATGGAAGCCT GTGCCCTTCT TCCAGATTTG GAAATCCTGC CCAGTGGGGA CCGCACAGAG
ATCGGTGAGA AGGGTGTGAA CCTGTCAGGG GGCCAGAAGC AGCGTGTGAG CCTGGCCCGG
GCTGTGTACT CTAACTCTGA CATCTACCTC TTTGATGACC CCCTCTCGGC TGTGGATGCA
CATGTTGGGA AGCACATCTT TGAGAAGGTG GTTGGTCCCA TGGGCCTACT GAAGAACAAG
ACACGGATCC TGGTCACCCA TGGTATCAGC TACCTGCCCC AAGTGGATGT CATCATTGTC
ATGAGTGGCG GCAAGATCTC AGAGATGGGT TCTTATCAGG AGCTGCTAGA CCGGGATGGG
GCCTTCGCTG AGTTCCTGCG CACCTATGCC AACGCTGAGC AGGACCTGGC CTCGGAGGAT
GACAGTGTCA GTGGTTCAGG GAAGGAGTCA AAGCCGGTGG AAAATGGGAT GCTGGTGACA
GACACCGTAG GAAAGCACCT GCAGAGGCAT CTCAGCAACT CGTCTTCCCA CAGTGGGGAT
ACCAGCCAGC AACACAGCAG CATAGCCGAA CTGCAGAAGG CTGGAGCTAA GGAGGAGACG
TGGAAGCTAA TGGAAGCAGA CAAGGCCCAG ACAGGGCAGG TGCAGCTGTC AGTGTACTGG
AACTACATGA AGGCCATTGG CCTCTTCATC ACCTTCTTGA GTATCTTCCT TTTCCTGTGC
AACCATGTAT CTGCACTGGC CTCTAACTAT TGGCTGAGCC TCTGGACAGA TGACCCCCCT
GTTGTCAATG GGACTCAGGC GAACAGGAAT TTTCGGCTGA GTGTCTATGG GGCCTTGGGC
ATCTTGCAAG GTGCAGCAAT ATTTGGCTAC TCCATGGCTG TGTCCATCGG GGGCATCTTT
GCCTCCCGTC GCTTGCACCT GGACCTGCTA TACAATGTTC TGCGATCACC CATGAGTTTC
TTTGAGCGTA CACCCAGTGG GAACCTAGTG AACCGATTCT CCAAGGAGCT GGACACAGTG
GACTCCATGA TCCCGCAGGT CATCAAGATG TTCATGGGTT CACTCTTCAG TGTCATTGGA
GCTGTCATCA TCATCCTACT GGCCACGCCC ATTGCCGCAG TCATCATCCC ACCCTTGGGT
CTGGTTTACT TCTTTGTGCA GAGGTTCTAT GTGGCTTCCT CAAGACAACT GAAGCGCCTG
GAGTCTGTCA GCCGTTCCCC TGTGTACTCA CACTTCAATG AGACCTTGCT GGGAGTCAGT
GTCATCCGTG CTTTTGAGGA GCAGGAGCGC TTCATTCACC AGAGTGACCT GAAAGTAGAT
GAGAACCAGA AGGCCTACTA CCCCAGCATT GTGGCCAACA GGTGGCTTGC TGTGCGCCTT
GAGTGTGTGG GCAACTGCAT TGTGCTGTTT GCTGCCCTCT TTGCAGTCAT CTCCCGGCAC
AGCCTCAGTG CTGGCTTGGT GGGCCTCTCT GTGTCTTACT CACTGCAGAT AACTGCATAC
TTGAACTGGC TGGTTCGAAT GTCCTCGGAG ATGGAGACCA ACATTGTGGC AGTGGAGAGA
CTGAAGGAGT ATTCTGAAAC AGAGAAGGAG GCTCCTTGGC AAATCCAGGA AACAGCTCCA
CCCAGCACCT GGCCCCATTC AGGCCGTGTA GAGTTCCGGG ATTACTGCCT GAGGTATCGA
GAAGACTTGG ACTTGGTTCT CAAGCACATA AATGTCACCA TTGAGGGTGG AGAAAAGGTG
GGTATTGTAG GTCGTACGGG AGCTGGGAAA TCATCTCTCA CCCTGGGTTT GTTCCGGATC
AATGAGTCTG CAGAAGGGGA GATCATCATT GATGGGGTCA ACATCGCCAA GATCGGCCTG
CACAACCTGC GCTTCAAGAT CACCATCATT CCACAGGATC CTGTTTTGTT CTCGGGTTCC
CTCCGCATGA ACTTGGACCC TTTCAGTCAG TATTCTGATG AAGAAGTCTG GATGGCCCTG
GAGCTTGCTC ACCTAAAGGG CTTTGTGTCA GCTTTGCCTG ACAAGCTGAA CCATGAGTGT
GCAGAAGGTG GAGAGAACCT GAGTGTGGGG CAGCGACAGC TTGTGTGCCT GGCCCGGGCT
CTGCTGAGGA AGACAAAGAT TCTAGTGTTG GACGAGGCTA CCGCAGCTGT GGACCTAGAG
ACAGATAACC TTATCCAGTC CACCATCCGG ACACAGTTTG AAGACTGTAC TGTGCTCACG
ATTGCTCATC GGCTTAACAC CATAATGGAC TACACGCGGG TGATTGTCCT GGACAAAGGA
GAAGTTCGGG AGTGTGGTGC ACCCTCTGAG CTCCTGCAGC AAAGAGGCAT CTTCTACAGC
ATGGCCAAGG ATGCTGGCTT GGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu79272
Clone ID Related Accession (Same CDS sequence) XM_017316888.1
Accession Version XM_017316888.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2346bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-22
Organism Mus musculus(House mouse)
Product multidrug resistance-associated protein 1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCGCTGC GCAGCTTCTG CAGCGCTGAT GGCTCCGATC CACTCTGGGA CTGGAATGTC 
ACATGGCACA CCAGCAACCC CGACTTTACC AAGTGCTTTC AGAACACGGT CCTCACATGG
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCTTCTATCT CTCTCGCCAT
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAACCA AAACTGCCTT AGGATTCTTT
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAGTG
CTCCGAGCCC CAGTGTTACT GGTCAGCCCA ACACTGCTGG GCATCACCAT GCTGCTCGCC
ACCTTTTTGA TACAGCTTGA ACGGAGGAAG GGAGTCCAAT CCTCGGGAAT TATGCTTACT
TTCTGGCTCG TAGCCCTACT CTGTGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC
TTAAAAAAGG ATGCTCATGT GGACGTGTTT CGAGATTCCA CGTTCTATCT GTACTTCACC
CTTGTGCTTG TTCAGCTCGT GCTGTCCTGC TTCTCAGACT GCTCACCCCT GTTCTCTGAA
ACTGTCCATG ACCGGAATCC ATGCCCAGAA TCCAGTGCCT CTTTCCTTTC CAGGATTACT
TTCTGGTGGA TTACAGGGAT GATGGTGCAC GGCTACCGCC AGCCCCTGGA GAGCAGTGAC
CTCTGGTCAT TGAATAAGGA GGACACATCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC
TGGAAGAAGG AATGTGATAA GTCAAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC
AAAGATCCCA GCAAGCCTAA GGGAAGTTCC CAGTTGGATG TGAATGAGGA GGTGGAGGCA
CTGATTGTCA AGTCACCCCA CAAGGATCGG GAGCCCTCTC TGTTCAAGGT GTTATACAAG
ACTTTTGGTC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG
TTTGCCGGCC CCAAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCTCCC
GACTGGCAGG GCTACTTTTA CACAGCACTG CTGTTTGTCA GCGCCTGTCT GCAGACACTG
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCAGTGGCA TGCGCATCAA GACTGCTGTG
GTGGGCGCTG TCTATCGTAA GGCTCTTTTG ATCACCAATG CAGCTAGAAA ATCTTCCACG
GTCGGAGAGA TTGTCAACCT CATGTCCGTG GATGCTCAGC GCTTCATGGA CTTGGCCACG
TACATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCATCC TAGCCCTCTA CTTCCTGTGG
CTGAGCCTGG GCCCTTCTGT GCTGGCTGGA GTGGCTGTGA TGATTCTCAT GGTACCCTTA
AATGCTGTGA TGGCCATGAA GACCAAGACC TACCAGGTGG CACACATGAA GAGCAAAGAC
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTCCTCAA GCTGTACGCC
TGGGAGCTGG CCTTCCAGGA CAAAGTCATG AGCATCAGGC AGGAGGAGCT CAAGGTGCTG
AAGAAATCTG CCTACTTGGC AGCTGTAGGC ACATTCACGT GGGTGTGCAC ACCTTTCCTG
GTGGCCCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGATG AGAGAAATAT CCTAGATGCA
AAGAAAGCCT TTGTGTCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTG
CCCATGGTTA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATTTTT
CTGTCTCATG AGGAGCTGGA GCCAGACAGC ATTGAGCGGA GGTCGATCAA GAGTGGCGAA
GGGAATAGCA TCACTGTGAA GAATGCAACC TTCACTTGGG CCAGGGGTGA ACCTCCCACA
CTGAATGGCA TCACCTTCTC CATTCCTGAA GGAGCCCTTG TGGCCGTGGT GGGCCAGGTA
GGCTGCGGGA AGTCATCTCT GCTGTCAGCC CTGCTGGCTG AGATGGACAA GGTGGAGGGA
CATGTGACTC TCAAGGGCTC CGTGGCCTAC GTGCCCCAGC AGGCCTGGAT TCAGAATGAC
TCTCTCCGAG AGAACATACT GTTTGGGCAC CCCCTGCAGG AAAATTACTA CAAGGCAGTT
ATGGAAGCCT GTGCCCTTCT TCCAGATTTG GAAATCCTGC CCAGTGGGGA CCGCACAGAG
ATCGGTGAGA AGGTGTCAGT GGTTCAGGGA AGGAGTCAAA GCCGGTGGAA AATGGGATGC
TGGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017172377.1
CDS85..2430
Translation

Target ORF information:

RefSeq Version XM_017316888.1
Organism Mus musculus(House mouse)
Definition Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017316888.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCGCTGC GCAGCTTCTG CAGCGCTGAT GGCTCCGATC CACTCTGGGA CTGGAATGTC 
ACATGGCACA CCAGCAACCC CGACTTTACC AAGTGCTTTC AGAACACGGT CCTCACATGG
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCTTCTATCT CTCTCGCCAT
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAACCA AAACTGCCTT AGGATTCTTT
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAGTG
CTCCGAGCCC CAGTGTTACT GGTCAGCCCA ACACTGCTGG GCATCACCAT GCTGCTCGCC
ACCTTTTTGA TACAGCTTGA ACGGAGGAAG GGAGTCCAAT CCTCGGGAAT TATGCTTACT
TTCTGGCTCG TAGCCCTACT CTGTGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC
TTAAAAAAGG ATGCTCATGT GGACGTGTTT CGAGATTCCA CGTTCTATCT GTACTTCACC
CTTGTGCTTG TTCAGCTCGT GCTGTCCTGC TTCTCAGACT GCTCACCCCT GTTCTCTGAA
ACTGTCCATG ACCGGAATCC ATGCCCAGAA TCCAGTGCCT CTTTCCTTTC CAGGATTACT
TTCTGGTGGA TTACAGGGAT GATGGTGCAC GGCTACCGCC AGCCCCTGGA GAGCAGTGAC
CTCTGGTCAT TGAATAAGGA GGACACATCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC
TGGAAGAAGG AATGTGATAA GTCAAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC
AAAGATCCCA GCAAGCCTAA GGGAAGTTCC CAGTTGGATG TGAATGAGGA GGTGGAGGCA
CTGATTGTCA AGTCACCCCA CAAGGATCGG GAGCCCTCTC TGTTCAAGGT GTTATACAAG
ACTTTTGGTC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG
TTTGCCGGCC CCAAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCTCCC
GACTGGCAGG GCTACTTTTA CACAGCACTG CTGTTTGTCA GCGCCTGTCT GCAGACACTG
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCAGTGGCA TGCGCATCAA GACTGCTGTG
GTGGGCGCTG TCTATCGTAA GGCTCTTTTG ATCACCAATG CAGCTAGAAA ATCTTCCACG
GTCGGAGAGA TTGTCAACCT CATGTCCGTG GATGCTCAGC GCTTCATGGA CTTGGCCACG
TACATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCATCC TAGCCCTCTA CTTCCTGTGG
CTGAGCCTGG GCCCTTCTGT GCTGGCTGGA GTGGCTGTGA TGATTCTCAT GGTACCCTTA
AATGCTGTGA TGGCCATGAA GACCAAGACC TACCAGGTGG CACACATGAA GAGCAAAGAC
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTCCTCAA GCTGTACGCC
TGGGAGCTGG CCTTCCAGGA CAAAGTCATG AGCATCAGGC AGGAGGAGCT CAAGGTGCTG
AAGAAATCTG CCTACTTGGC AGCTGTAGGC ACATTCACGT GGGTGTGCAC ACCTTTCCTG
GTGGCCCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGATG AGAGAAATAT CCTAGATGCA
AAGAAAGCCT TTGTGTCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTG
CCCATGGTTA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATTTTT
CTGTCTCATG AGGAGCTGGA GCCAGACAGC ATTGAGCGGA GGTCGATCAA GAGTGGCGAA
GGGAATAGCA TCACTGTGAA GAATGCAACC TTCACTTGGG CCAGGGGTGA ACCTCCCACA
CTGAATGGCA TCACCTTCTC CATTCCTGAA GGAGCCCTTG TGGCCGTGGT GGGCCAGGTA
GGCTGCGGGA AGTCATCTCT GCTGTCAGCC CTGCTGGCTG AGATGGACAA GGTGGAGGGA
CATGTGACTC TCAAGGGCTC CGTGGCCTAC GTGCCCCAGC AGGCCTGGAT TCAGAATGAC
TCTCTCCGAG AGAACATACT GTTTGGGCAC CCCCTGCAGG AAAATTACTA CAAGGCAGTT
ATGGAAGCCT GTGCCCTTCT TCCAGATTTG GAAATCCTGC CCAGTGGGGA CCGCACAGAG
ATCGGTGAGA AGGTGTCAGT GGTTCAGGGA AGGAGTCAAA GCCGGTGGAA AATGGGATGC
TGGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu68194
Clone ID Related Accession (Same CDS sequence) XM_006521839.3
Accession Version XM_006521839.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 4560bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-22
Organism Mus musculus(House mouse)
Product multidrug resistance-associated protein 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521839.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
ATGGCGCTGC GCAGCTTCTG CAGCGCTGAT GGCTCCGATC CACTCTGGGA CTGGAATGTC 
ACATGGCACA CCAGCAACCC CGACTTTACC AAGTGCTTTC AGAACACGGT CCTCACATGG
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCTTCTATCT CTCTCGCCAT
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAACCA AAACTGCCTT AGGATTCTTT
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAGTG
CTCCGAGCCC CAGTGTTACT GGTCAGCCCA ACACTGCTGG GCATCACCAT GCTGCTCGCC
ACCTTTTTGA TACAGCTTGA ACGGAGGAAG GGAGTCCAAT CCTCGGGAAT TATGCTTACT
TTCTGGCTCG TAGCCCTACT CTGTGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC
TTAAAAAAGG ATGCTCATGT GGACGTGTTT CGAGATTCCA CGTTCTATCT GTACTTCACC
CTTGTGCTTG TTCAGCTCGT GCTGTCCTGC TTCTCAGACT GCTCACCCCT GTTCTCTGAA
ACTGTCCATG ACCGGAATCC ATGCCCAGAA TCCAGTGCCT CTTTCCTTTC CAGGATTACT
TTCTGGTGGA TTACAGGGAT GATGGTGCAC GGCTACCGCC AGCCCCTGGA GAGCAGTGAC
CTCTGGTCAT TGAATAAGGA GGACACATCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC
TGGAAGAAGG AATGTGATAA GTCAAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC
AAAGATCCCA GCAAGCCTAA GGGAAGTTCC CAGTTGGATG TGAATGAGGA GGTGGAGGCA
CTGATTGTCA AGTCACCCCA CAAGGATCGG GAGCCCTCTC TGTTCAAGGT GTTATACAAG
ACTTTTGGTC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG
TTTGCCGGCC CCAAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCTCCC
GACTGGCAGG GCTACTTTTA CACAGCACTG CTGTTTGTCA GCGCCTGTCT GCAGACACTG
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCAGTGGCA TGCGCATCAA GACTGCTGTG
GTGGGCGCTG TCTATCGTAA GGCTCTTTTG ATCACCAATG CAGCTAGAAA ATCTTCCACG
GTCGGAGAGA TTGTCAACCT CATGTCCGTG GATGCTCAGC GCTTCATGGA CTTGGCCACG
TACATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCATCC TAGCCCTCTA CTTCCTGTGG
CTGAGCCTGG GCCCTTCTGT GCTGGCTGGA GTGGCTGTGA TGATTCTCAT GGTACCCTTA
AATGCTGTGA TGGCCATGAA GACCAAGACC TACCAGGTGG CACACATGAA GAGCAAAGAC
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTCCTCAA GCTGTACGCC
TGGGAGCTGG CCTTCCAGGA CAAAGTCATG AGCATCAGGC AGGAGGAGCT CAAGGTGCTG
AAGAAATCTG CCTACTTGGC AGCTGTAGGC ACATTCACGT GGGTGTGCAC ACCTTTCCTG
GTGGCCCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGATG AGAGAAATAT CCTAGATGCA
AAGAAAGCCT TTGTGTCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTG
CCCATGGTTA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATTTTT
CTGTCTCATG AGGAGCTGGA GCCAGACAGC ATTGAGCGGA GGTCGATCAA GAGTGGCGAA
GGGAATAGCA TCACTGTGAA GAATGCAACC TTCACTTGGG CCAGGGGTGA ACCTCCCACA
CTGAATGGCA TCACCTTCTC CATTCCTGAA GGAGCCCTTG TGGCCGTGGT GGGCCAGGTA
GGCTGCGGGA AGTCATCTCT GCTGTCAGCC CTGCTGGCTG AGATGGACAA GGTGGAGGGA
CATGTGACTC TCAAGGGCTC CGTGGCCTAC GTGCCCCAGC AGGCCTGGAT TCAGAATGAC
TCTCTCCGAG AGAACATACT GTTTGGGCAC CCCCTGCAGG AAAATTACTA CAAGGCAGTT
ATGGAAGCCT GTGCCCTTCT TCCAGATTTG GAAATCCTGC CCAGTGGGGA CCGCACAGAG
ATCGGTGAGA AGGGTGTGAA CCTGTCAGGG GGCCAGAAGC AGCGTGTGAG CCTGGCCCGG
GCTGTGTACT CTAACTCTGA CATCTACCTC TTTGATGACC CCCTCTCGGC TGTGGATGCA
CATGTTGGGA AGCACATCTT TGAGAAGGTG GTTGGTCCCA TGGGCCTACT GAAGAACAAG
ACACGGATCC TGGTCACCCA TGGTATCAGC TACCTGCCCC AAGTGGATGT CATCATTGTC
ATGAGTGGCG GCAAGATCTC AGAGATGGGT TCTTATCAGG AGCTGCTAGA CCGGGATGGG
GCCTTCGCTG AGTTCCTGCG CACCTATGCC AACGCTGAGC AGGACCTGGC CTCGGAGGAT
GACAGTGTCA GTGGTTCAGG GAAGGAGTCA AAGCCGGTGG AAAATGGGAT GCTGGTGACA
GACACCGTAG GAAAGCACCT GCAGAGTGGG GATACCAGCC AGCAACACAG CAGCATAGCC
GAACTGCAGA AGGCTGGAGC TAAGGAGGAG ACGTGGAAGC TAATGGAAGC AGACAAGGCC
CAGACAGGGC AGGTGCAGCT GTCAGTGTAC TGGAACTACA TGAAGGCCAT TGGCCTCTTC
ATCACCTTCT TGAGTATCTT CCTTTTCCTG TGCAACCATG TATCTGCACT GGCCTCTAAC
TATTGGCTGA GCCTCTGGAC AGATGACCCC CCTGTTGTCA ATGGGACTCA GGCGAACAGG
AATTTTCGGC TGAGTGTCTA TGGGGCCTTG GGCATCTTGC AAGGTGCAGC AATATTTGGC
TACTCCATGG CTGTGTCCAT CGGGGGCATC TTTGCCTCCC GTCGCTTGCA CCTGGACCTG
CTATACAATG TTCTGCGATC ACCCATGAGT TTCTTTGAGC GTACACCCAG TGGGAACCTA
GTGAACCGAT TCTCCAAGGA GCTGGACACA GTGGACTCCA TGATCCCGCA GGTCATCAAG
ATGTTCATGG GTTCACTCTT CAGTGTCATT GGAGCTGTCA TCATCATCCT ACTGGCCACG
CCCATTGCCG CAGTCATCAT CCCACCCTTG GGTCTGGTTT ACTTCTTTGT GCAGAGGTTC
TATGTGGCTT CCTCAAGACA ACTGAAGCGC CTGGAGTCTG TCAGCCGTTC CCCTGTGTAC
TCACACTTCA ATGAGACCTT GCTGGGAGTC AGTGTCATCC GTGCTTTTGA GGAGCAGGAG
CGCTTCATTC ACCAGAGTGA CCTGAAAGTA GATGAGAACC AGAAGGCCTA CTACCCCAGC
ATTGTGGCCA ACAGGTGGCT TGCTGTGCGC CTTGAGTGTG TGGGCAACTG CATTGTGCTG
TTTGCTGCCC TCTTTGCAGT CATCTCCCGG CACAGCCTCA GTGCTGGCTT GGTGGGCCTC
TCTGTGTCTT ACTCACTGCA GATAACTGCA TACTTGAACT GGCTGGTTCG AATGTCCTCG
GAGATGGAGA CCAACATTGT GGCAGTGGAG AGACTGAAGG AGTATTCTGA AACAGAGAAG
GAGGCTCCTT GGCAAATCCA GGAAACAGCT CCACCCAGCA CCTGGCCCCA TTCAGGCCGT
GTAGAGTTCC GGGATTACTG CCTGAGGTAT CGAGAAGACT TGGACTTGGT TCTCAAGCAC
ATAAATGTCA CCATTGAGGG TGGAGAAAAG GTGGGTATTG TAGGTCGTAC GGGAGCTGGG
AAATCATCTC TCACCCTGGG TTTGTTCCGG ATCAATGAGT CTGCAGAAGG GGAGATCATC
ATTGATGGGG TCAACATCGC CAAGATCGGC CTGCACAACC TGCGCTTCAA GATCACCATC
ATTCCACAGG ATCCTGTTTT GTTCTCGGGT TCCCTCCGCA TGAACTTGGA CCCTTTCAGT
CAGTATTCTG ATGAAGAAGT CTGGATGGCC CTGGAGCTTG CTCACCTAAA GGGCTTTGTG
TCAGCTTTGC CTGACAAGCT GAACCATGAG TGTGCAGAAG GTGGAGAGAA CCTGAGTGTG
GGGCAGCGAC AGCTTGTGTG CCTGGCCCGG GCTCTGCTGA GGAAGACAAA GATTCTAGTG
TTGGACGAGG CTACCGCAGC TGTGGACCTA GAGACAGATA ACCTTATCCA GTCCACCATC
CGGACACAGT TTGAAGACTG TACTGTGCTC ACGATTGCTC ATCGGCTTAA CACCATAATG
GACTACACGC GGGTGATTGT CCTGGACAAA GGAGAAGTTC GGGAGTGTGG TGCACCCTCT
GAGCTCCTGC AGCAAAGAGG CATCTTCTAC AGCATGGCCA AGGATGCTGG CTTGGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006521902.2
CDS84..4643
Misc Feature(1)102..4637
Misc Feature(2)1071..1874
Misc Feature(3)2013..2618
Misc Feature(4)2115..2138
Misc Feature(5)order(2124..2129,2133..2141,2220..2222,2457..2462,2562..2564)
Misc Feature(6)2211..2222
Misc Feature(7)2385..2414
Misc Feature(8)2445..2462
Misc Feature(9)2469..2480
Misc Feature(10)2550..2570
Misc Feature(11)2979..3779
Misc Feature(12)3918..4580
Translation

Target ORF information:

RefSeq Version XM_006521839.3
Organism Mus musculus(House mouse)
Definition Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006521839.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
ATGGCGCTGC GCAGCTTCTG CAGCGCTGAT GGCTCCGATC CACTCTGGGA CTGGAATGTC 
ACATGGCACA CCAGCAACCC CGACTTTACC AAGTGCTTTC AGAACACGGT CCTCACATGG
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCTTCTATCT CTCTCGCCAT
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAACCA AAACTGCCTT AGGATTCTTT
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAGTG
CTCCGAGCCC CAGTGTTACT GGTCAGCCCA ACACTGCTGG GCATCACCAT GCTGCTCGCC
ACCTTTTTGA TACAGCTTGA ACGGAGGAAG GGAGTCCAAT CCTCGGGAAT TATGCTTACT
TTCTGGCTCG TAGCCCTACT CTGTGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC
TTAAAAAAGG ATGCTCATGT GGACGTGTTT CGAGATTCCA CGTTCTATCT GTACTTCACC
CTTGTGCTTG TTCAGCTCGT GCTGTCCTGC TTCTCAGACT GCTCACCCCT GTTCTCTGAA
ACTGTCCATG ACCGGAATCC ATGCCCAGAA TCCAGTGCCT CTTTCCTTTC CAGGATTACT
TTCTGGTGGA TTACAGGGAT GATGGTGCAC GGCTACCGCC AGCCCCTGGA GAGCAGTGAC
CTCTGGTCAT TGAATAAGGA GGACACATCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC
TGGAAGAAGG AATGTGATAA GTCAAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC
AAAGATCCCA GCAAGCCTAA GGGAAGTTCC CAGTTGGATG TGAATGAGGA GGTGGAGGCA
CTGATTGTCA AGTCACCCCA CAAGGATCGG GAGCCCTCTC TGTTCAAGGT GTTATACAAG
ACTTTTGGTC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG
TTTGCCGGCC CCAAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCTCCC
GACTGGCAGG GCTACTTTTA CACAGCACTG CTGTTTGTCA GCGCCTGTCT GCAGACACTG
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCAGTGGCA TGCGCATCAA GACTGCTGTG
GTGGGCGCTG TCTATCGTAA GGCTCTTTTG ATCACCAATG CAGCTAGAAA ATCTTCCACG
GTCGGAGAGA TTGTCAACCT CATGTCCGTG GATGCTCAGC GCTTCATGGA CTTGGCCACG
TACATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCATCC TAGCCCTCTA CTTCCTGTGG
CTGAGCCTGG GCCCTTCTGT GCTGGCTGGA GTGGCTGTGA TGATTCTCAT GGTACCCTTA
AATGCTGTGA TGGCCATGAA GACCAAGACC TACCAGGTGG CACACATGAA GAGCAAAGAC
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTCCTCAA GCTGTACGCC
TGGGAGCTGG CCTTCCAGGA CAAAGTCATG AGCATCAGGC AGGAGGAGCT CAAGGTGCTG
AAGAAATCTG CCTACTTGGC AGCTGTAGGC ACATTCACGT GGGTGTGCAC ACCTTTCCTG
GTGGCCCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGATG AGAGAAATAT CCTAGATGCA
AAGAAAGCCT TTGTGTCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTG
CCCATGGTTA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATTTTT
CTGTCTCATG AGGAGCTGGA GCCAGACAGC ATTGAGCGGA GGTCGATCAA GAGTGGCGAA
GGGAATAGCA TCACTGTGAA GAATGCAACC TTCACTTGGG CCAGGGGTGA ACCTCCCACA
CTGAATGGCA TCACCTTCTC CATTCCTGAA GGAGCCCTTG TGGCCGTGGT GGGCCAGGTA
GGCTGCGGGA AGTCATCTCT GCTGTCAGCC CTGCTGGCTG AGATGGACAA GGTGGAGGGA
CATGTGACTC TCAAGGGCTC CGTGGCCTAC GTGCCCCAGC AGGCCTGGAT TCAGAATGAC
TCTCTCCGAG AGAACATACT GTTTGGGCAC CCCCTGCAGG AAAATTACTA CAAGGCAGTT
ATGGAAGCCT GTGCCCTTCT TCCAGATTTG GAAATCCTGC CCAGTGGGGA CCGCACAGAG
ATCGGTGAGA AGGGTGTGAA CCTGTCAGGG GGCCAGAAGC AGCGTGTGAG CCTGGCCCGG
GCTGTGTACT CTAACTCTGA CATCTACCTC TTTGATGACC CCCTCTCGGC TGTGGATGCA
CATGTTGGGA AGCACATCTT TGAGAAGGTG GTTGGTCCCA TGGGCCTACT GAAGAACAAG
ACACGGATCC TGGTCACCCA TGGTATCAGC TACCTGCCCC AAGTGGATGT CATCATTGTC
ATGAGTGGCG GCAAGATCTC AGAGATGGGT TCTTATCAGG AGCTGCTAGA CCGGGATGGG
GCCTTCGCTG AGTTCCTGCG CACCTATGCC AACGCTGAGC AGGACCTGGC CTCGGAGGAT
GACAGTGTCA GTGGTTCAGG GAAGGAGTCA AAGCCGGTGG AAAATGGGAT GCTGGTGACA
GACACCGTAG GAAAGCACCT GCAGAGTGGG GATACCAGCC AGCAACACAG CAGCATAGCC
GAACTGCAGA AGGCTGGAGC TAAGGAGGAG ACGTGGAAGC TAATGGAAGC AGACAAGGCC
CAGACAGGGC AGGTGCAGCT GTCAGTGTAC TGGAACTACA TGAAGGCCAT TGGCCTCTTC
ATCACCTTCT TGAGTATCTT CCTTTTCCTG TGCAACCATG TATCTGCACT GGCCTCTAAC
TATTGGCTGA GCCTCTGGAC AGATGACCCC CCTGTTGTCA ATGGGACTCA GGCGAACAGG
AATTTTCGGC TGAGTGTCTA TGGGGCCTTG GGCATCTTGC AAGGTGCAGC AATATTTGGC
TACTCCATGG CTGTGTCCAT CGGGGGCATC TTTGCCTCCC GTCGCTTGCA CCTGGACCTG
CTATACAATG TTCTGCGATC ACCCATGAGT TTCTTTGAGC GTACACCCAG TGGGAACCTA
GTGAACCGAT TCTCCAAGGA GCTGGACACA GTGGACTCCA TGATCCCGCA GGTCATCAAG
ATGTTCATGG GTTCACTCTT CAGTGTCATT GGAGCTGTCA TCATCATCCT ACTGGCCACG
CCCATTGCCG CAGTCATCAT CCCACCCTTG GGTCTGGTTT ACTTCTTTGT GCAGAGGTTC
TATGTGGCTT CCTCAAGACA ACTGAAGCGC CTGGAGTCTG TCAGCCGTTC CCCTGTGTAC
TCACACTTCA ATGAGACCTT GCTGGGAGTC AGTGTCATCC GTGCTTTTGA GGAGCAGGAG
CGCTTCATTC ACCAGAGTGA CCTGAAAGTA GATGAGAACC AGAAGGCCTA CTACCCCAGC
ATTGTGGCCA ACAGGTGGCT TGCTGTGCGC CTTGAGTGTG TGGGCAACTG CATTGTGCTG
TTTGCTGCCC TCTTTGCAGT CATCTCCCGG CACAGCCTCA GTGCTGGCTT GGTGGGCCTC
TCTGTGTCTT ACTCACTGCA GATAACTGCA TACTTGAACT GGCTGGTTCG AATGTCCTCG
GAGATGGAGA CCAACATTGT GGCAGTGGAG AGACTGAAGG AGTATTCTGA AACAGAGAAG
GAGGCTCCTT GGCAAATCCA GGAAACAGCT CCACCCAGCA CCTGGCCCCA TTCAGGCCGT
GTAGAGTTCC GGGATTACTG CCTGAGGTAT CGAGAAGACT TGGACTTGGT TCTCAAGCAC
ATAAATGTCA CCATTGAGGG TGGAGAAAAG GTGGGTATTG TAGGTCGTAC GGGAGCTGGG
AAATCATCTC TCACCCTGGG TTTGTTCCGG ATCAATGAGT CTGCAGAAGG GGAGATCATC
ATTGATGGGG TCAACATCGC CAAGATCGGC CTGCACAACC TGCGCTTCAA GATCACCATC
ATTCCACAGG ATCCTGTTTT GTTCTCGGGT TCCCTCCGCA TGAACTTGGA CCCTTTCAGT
CAGTATTCTG ATGAAGAAGT CTGGATGGCC CTGGAGCTTG CTCACCTAAA GGGCTTTGTG
TCAGCTTTGC CTGACAAGCT GAACCATGAG TGTGCAGAAG GTGGAGAGAA CCTGAGTGTG
GGGCAGCGAC AGCTTGTGTG CCTGGCCCGG GCTCTGCTGA GGAAGACAAA GATTCTAGTG
TTGGACGAGG CTACCGCAGC TGTGGACCTA GAGACAGATA ACCTTATCCA GTCCACCATC
CGGACACAGT TTGAAGACTG TACTGTGCTC ACGATTGCTC ATCGGCTTAA CACCATAATG
GACTACACGC GGGTGATTGT CCTGGACAAA GGAGAAGTTC GGGAGTGTGG TGCACCCTCT
GAGCTCCTGC AGCAAAGAGG CATCTTCTAC AGCATGGCCA AGGATGCTGG CTTGGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.
Cell reports16(10)2711-22(2016 Sep)
Steinmetz CC,Tatavarty V,Sugino K,Shima Y,Joseph A,Lin H,Rutlin M,Lambo M,Hempel CM,Okaty BW,Paradis S,Nelson SB,Turrigiano GG


book

Multidrug resistance associated protein-1 (MRP1) deficiency attenuates endothelial dysfunction in diabetes.
Journal of diabetes and its complications30(4)623-7(2016 May-Jun)
Neuser J,Fraccarollo D,Wick M,Bauersachs J,Widder JD


book

Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells.
The Journal of biological chemistry291(19)10089-103(2016 May)
Gordillo GM,Biswas A,Khanna S,Spieldenner JM,Pan X,Sen CK


book

Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier.
British journal of pharmacology173(3)497-510(2016 Feb)
Chapy H,Saubaméa B,Tournier N,Bourasset F,Behar-Cohen F,Declèves X,Scherrmann JM,Cisternino S


book

Maternal bile acid transporter deficiency promotes neonatal demise.
Nature communications68186(2015 Sep)
Zhang Y,Li F,Wang Y,Pitre A,Fang ZZ,Frank MW,Calabrese C,Krausz KW,Neale G,Frase S,Vogel P,Rock CO,Gonzalez FJ,Schuetz JD


 
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