Slc3a1 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Slc3a1 |
| Entrez Gene ID | 20532 |
| Full Name | solute carrier family 3, member 1 |
| Synonyms | D2H,NBAT,NTAA,RBAT |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_009205.2 | NP_033231.2 | neutral and basic amino acid transport protein rBAT |
| Homo sapiens (human) | SLC3A1 | NP_000332.2 |
| Danio rerio (zebrafish) | slc3a1 | XP_685969.3 |
| Bos taurus (cattle) | SLC3A1 | NP_001029805.1 |
| Mus musculus (house mouse) | Slc3a1 | NP_033231.2 |
| Gallus gallus (chicken) | SLC3A1 | XP_426125.3 |
| Neurospora crassa | NCU06523 | XP_961795.1 |
| Canis lupus familiaris (dog) | SLC3A1 | NP_001003109.1 |
| Drosophila melanogaster (fruit fly) | Mal-B1 | NP_609522.1 |
| Drosophila melanogaster (fruit fly) | Mal-B2 | NP_609523.2 |
| Pan troglodytes (chimpanzee) | SLC3A1 | XP_515443.2 |
| SLC3A1 | XP_001112327.2 | |
| Magnaporthe oryzae (rice blast fungus) | MGG_07547 | XP_003711461.1 |
| Xenopus tropicalis (tropical clawed frog) | slc3a1 | NP_001072903.1 |
| Rattus norvegicus (Norway rat) | Slc3a1 | NP_058912.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008965 | XP_319713.4 |
Related articles in PubMed
?-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria.
Zee T, Bose N, Zee J, Beck JN, Yang S, Parihar J, Yang M, Damodar S, Hall D, O'Leary MN, Ramanathan A, Gerona RR, Killilea DW, Chi T, Tischfield J, Sahota A, Kahn A, Stoller ML, Kapahi P
Nature medicine23(3)288-290(2017 Mar)
Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.
Nagamori S, Wiriyasermkul P, Guarch ME, Okuyama H, Nakagomi S, Tadagaki K, Nishinaka Y, Bodoy S, Takafuji K, Okuda S, Kurokawa J, Ohgaki R, Nunes V, Palac?n M, Kanai Y
Proceedings of the National Academy of Sciences of the United States of America113(3)775-80(2016 Jan)
Novel cystine ester mimics for the treatment of cystinuria-induced urolithiasis in a knockout mouse model.
Sahota A, Parihar JS, Capaccione KM, Yang M, Noll K, Gordon D, Reimer D, Yang I, Buckley BT, Polunas M, Reuhl KR, Lewis MR, Ward MD, Goldfarb DS, Tischfield JA
Urology84(5)1249.e9-15(2014 Nov)
An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice.
Livrozet M, Vandermeersch S, Mesnard L, Thioulouse E, Jaubert J, Boffa JJ, Haymann JP, Baud L, Bazin D, Daudon M, Letavernier E
PloS one9(7)e102700(2014)
Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.
Templin JS, Bang SJ, Soiza-Reilly M, Berde CB, Commons KG
Brain research14571-12(2012 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a membrane protein AGT1/SLC7A13 is the second partner of rBAT.
Title: Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.
In 129S2/SvPasCrl mice, the heavy subunit RBAT of the tetrameric transporter of dibasic amino acids was absent in proximal tubules and identified was a single pathogenic mutation in a highly conserved region of the Slc3a1 gene.
Title: An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice.
This study demonistrated that slc3a1 gene expression in mouse dorsal raphe nucleus
Title: Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.
Slc3A1-deficient mice develop cystinuria type I
Title: A mouse model for cystinuria type I.
a decreasing expression gradient of heterodimeric rBAT-b(0,+)AT along the proximal tubule is responsible for virtually all apical cystine reabsorption
Title: rBAT-b(0,+)AT heterodimer is the main apical reabsorption system for cystine in the kidney.
The following Slc3a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc3a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu14723 | |
| Clone ID Related Accession (Same CDS sequence) | NM_009205.2 | |
| Accession Version | NM_009205.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-23 | |
| Organism | Mus musculus(house mouse) | |
| Product | neutral and basic amino acid transport protein rBAT | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA493293.1, AK132275.1 and AI326967.1. On Dec 8, 2006 this sequence version replaced NM_009205.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D88533.1, AK132275.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGATGAGG ACAAAGGCAA GAGAGACCCC ATCCAAATGA GTTTGAAGGG ATGCCGAACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_033231.2 |
| CDS | 86..2143 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_009205.2 |
ORF Insert Sequence:
1 | ATGGATGAGG ACAAAGGCAA GAGAGACCCC ATCCAAATGA GTTTGAAGGG ATGCCGAACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
?-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. |
|
Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1. |
|
Novel cystine ester mimics for the treatment of cystinuria-induced urolithiasis in a knockout mouse model. |
|
An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice. |
|
Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas. |