Gene Symbol | Dtx3l |
Entrez Gene ID | 209200 |
Full Name | deltex 3-like, E3 ubiquitin ligase |
Synonyms | AU042200,BC023741 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Dtx3l cDNA ORF clone
gRNAs
Gene Symbol | Dtx3l |
Entrez Gene ID | 209200 |
Full Name | deltex 3-like, E3 ubiquitin ligase |
Synonyms | AU042200,BC023741 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001013371.2 | NP_001013389.2 | E3 ubiquitin-protein ligase DTX3L |
Homo sapiens (human) | DTX3L | NP_612144.1 |
Pan troglodytes (chimpanzee) | DTX3L | XP_526285.1 |
Mus musculus (house mouse) | Dtx3l | NP_001013389.2 |
Canis lupus familiaris (dog) | DTX3L | XP_535762.2 |
Rattus norvegicus (Norway rat) | Dtx3l | NP_001102523.1 |
Bos taurus (cattle) | DTX3L | NP_001179325.1 |
DTX3L | XP_001112746.1 | |
Gallus gallus (chicken) | DTX3L | XP_422114.4 |
Laminar flow downregulates Notch activity to promote lymphatic sprouting.
Choi D, Park E, Jung E, Seong YJ, Yoo J, Lee E, Hong M, Lee S, Ishida H, Burford J, Peti-Peterdi J, Adams RH, Srikanth S, Gwack Y, Chen CS, Vogel HJ, Koh CJ, Wong AK, Hong YK
The Journal of clinical investigation127(4)1225-1240(2017 Apr)
PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ
Nature immunology16(12)1215-27(2015 Dec)
The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues.
Hakm? A, Huber A, Doll? P, Schreiber V
Developmental dynamics : an official publication of the American Association of Anatomists237(1)209-15(2008 Jan)
Transcriptome analysis of mouse stem cells and early embryos.
Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS
PLoS biology1(3)E74(2003 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate that PARP polymerase PARP9-E3 ligase DTX3L interacts with STAT1 transcription factor and enhances translocation of STAT1 to the nucleus.
Title: PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
The following Dtx3l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dtx3l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu11435 | |
Clone ID Related Accession (Same CDS sequence) | NM_001013371.2 | |
Accession Version | NM_001013371.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase DTX3L | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN668148.1, AK146802.1 and AC129574.8. On Mar 22, 2007 this sequence version replaced NM_001013371.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by mRNA and EST alignments. ##Evidence-Data-START## Transcript exon combination :: BC085093.1, AK146802.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTTCCA GTCCCGACCC GCCGTCCCCG CTACTCGTAC GGCTGCGGGA GTCCATCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001013389.2 |
CDS | 151..2397 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCTTCCA GTCCCGACCC GCCGTCCCCG CTACTCGTAC GGCTGCGGGA GTCCATCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Laminar flow downregulates Notch activity to promote lymphatic sprouting. |
PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection. |
The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues. |
Transcriptome analysis of mouse stem cells and early embryos. |