Cdk5rap2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdk5rap2
Entrez Gene ID	214444
Full Name	CDK5 regulatory subunit associated protein 2
Synonyms	2900018K03Rik,an,mKIAA1633
General protein information	Preferred Names CDK5 regulatory subunit associated protein 2 Names CDK5 regulatory subunit-associated protein 2 CDK5 activator-binding protein C48
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 C2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001313762.1	NP_001300691.1	CDK5 regulatory subunit-associated protein 2 isoform 2
NM_145990.4	NP_666102.2	CDK5 regulatory subunit-associated protein 2 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CDK5RAP2	NP_001035901.1
Bos taurus (cattle)	CDK5RAP2	NP_001179098.1
Rattus norvegicus (Norway rat)	Cdk5rap2	NP_775157.2
Gallus gallus (chicken)	CDK5RAP2	XP_001234726.3
Homo sapiens (human)	CDK5RAP2	NP_060719.4
	LOC701442	XP_002800046.1
Canis lupus familiaris (dog)	CDK5RAP2	XP_005627061.1
Mus musculus (house mouse)	Cdk5rap2	NP_666102.2

Gene Ontology
Bibliography

Related articles in PubMed

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Gao FJ, Shi L, Hines T, Hebbar S, Neufeld KL, Smith DS
Molecular biology of the cell28(5)587-599(2017 Mar)

CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development.
Zaqout S, Bessa P, Kr?mer N, Stoltenburg-Didinger G, Kaindl AM
Stem cell reports8(2)198-204(2017 02)

Divergent regulation of functionally distinct ?-tubulin complexes during differentiation.
Muroyama A, Seldin L, Lechler T
The Journal of cell biology213(6)679-92(2016 Jun)

Species-Specific Expression of Full-Length and Alternatively Spliced Variant Forms of CDK5RAP2.
Park JS, Lee MK, Kang S, Jin Y, Fu S, Rosales JL, Lee KY
PloS one10(11)e0142577(2015)

Novel Alternative Splice Variants of Mouse Cdk5rap2.
Kraemer N, Issa-Jahns L, Neubert G, Ravindran E, Mani S, Ninnemann O, Kaindl AM
PloS one10(8)e0136684(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We highlight that infertility in Cdk5rap2 mutant mice is secondary to a lack of spermatogenic cells in adult mice as a result of an early developmental defect in the germ cells through mitotic delay, prolonged cell cycle, and apoptosis.
Title: CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development.

In Cdk5rap2-depleted neural embryonic stem cells there is an increase in cell death in differentiating cells.
Title: Loss of CDK5RAP2 affects neural but not non-neural mESC differentiation into cardiomyocytes.

mouse expresses only one form of CDK5RAP2 that is equivalent to the human and rat alternatively spliced variant forms
Title: Species-Specific Expression of Full-Length and Alternatively Spliced Variant Forms of CDK5RAP2.

this study revealed the presence of previously unknown splice variants of the Cdk5rap2 gene that are at least in part accountable for the lack of microcephaly in the mice.
Title: Novel Alternative Splice Variants of Mouse Cdk5rap2.

This study demonistrated that CDK5RAP2 is a key molecule that mediates functional interaction and is essential for centrosomal targeting of Aurora-A.
Title: Activation of Aurora-A is essential for neuronal migration via modulation of microtubule organization.

The following Cdk5rap2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdk5rap2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu13597	NM_145990.4 Latest version!	Mus musculus CDK5 regulatory subunit associated protein 2 (Cdk5rap2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1336.30 $1909.00
OMu32821	NM_001313762.1 Latest version!	Mus musculus CDK5 regulatory subunit associated protein 2 (Cdk5rap2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdk5rap2 ( NM_145990.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666102.2 Mus musculus CDK5 regulatory subunit associated protein 2 (Cdk5rap2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu13597
Clone ID Related Accession (Same CDS sequence)	NM_145990.4
Accession Version	NM_145990.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5469bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	CDK5 regulatory subunit-associated protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF738512.1, CN698992.1, BC086696.1 and AL929409.5. On Sep 1, 2015 this sequence version replaced NM_145990.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.95724.1, AK129411.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTCGG GGATGGAAGA GGAAGGCGCC CTGCCTGGGA CCCTCAGCGG TTGCAGTGGC 
CTTCACCCTG TTCTGCCAAG TGACCTGGAT GTCATCAGTG ACACTTCTGG CTTGGGAAAT 
GGAGTGCTCC CAAGCATGTC AGAAGAAAAG GTTTCTCCCA CCAGAGCCCG GAACATGAAG 
GACTTTGAAA ACCAAATCAC TGAGCTGAAG AAGGAGAACT TCAATCTAAA GCTCCGGATC 
TACTTCCTGG AGGAGAGAAT CCAGCAGGAG TTTGCTGGCC CCACCGAGCA CATCTACAAG 
ACGAACATTG AACTCAAGGT GGAAGTGGAA AGTCTGAAGC GCGAGCTCCA GGAGAAAGAT 
CAGTTGCTCG TCAAAGCCTC CAAAGCGGTG GAGAGCCTAG CAGAACGGGG TGGTTCTGAA 
GTCCAGCGGG TGAAAGAAGA TGCAAGGAAG AAGGTGCAGC AGGTGGAAGA CCTCCTAACG 
AAAAGGATAC ATCTTCTAGA AGAAGATGTG AAAGCCGCCC AGGCAGAACT GGAGAAGGCC 
TTTGCGGGGA CAGAAACAGA GAAGGCTCTT CGGCTCAGCT TAGAAAGCAA GCTCTCGGCG 
ATGAAGAAGA TGCAGGAGGG GGACCTGGAG ATGACTCTGG CTCTGGAAGA GAAGGACAGA 
CTGATTGAGG AGTTGAAGCT GTCTTTGAAG AGCAAAGAAG CTTTAATTCA GTGCCTTAAA 
GAGGAAAAAT CTCAGATGGC ATCTCCTGAC GAGAACGTGT CATCTGGAGA ACTCCGAGGA 
CTTTCTGCCA CTCTGAGGGA AGAAAAAGAG AGAGACGCTG AGGAATGGCA GAAGGAGAGA 
AACCACTTTG AAGAGAGGAT CCAGGCACTT CAGGAGGACC TGAGAGAGAA GGAAAGAGAA 
ATTGCTACAG AGAAGAAAAA TAACTTAAAG AGTTATAAAG CCATTCAGGG TCTAACCATG 
GCATTAAAAT CAAAGGAAAG AGAGGTTGAA GAACTTGATT CCAAAATCAA AGAGGTCACT 
ACGGACTCCA CCAAAGGCAG AGAGGATCCC TTAAAAACCC AGATCCCCAG ATTCCAGCTA 
AGAGAGGGGT CTGAGGACTG TGAAGCTGCG CTGGTAGAGA AGGAAGCCCT ATTGGCCAAG 
CTACACTCAG AAAATGTCAC AAAGAGCACT GAGAACCATA GGTTGCTCAG GAATGTTAAA 
AAGGTCACCC AGGAGTTGAA TGACTTGAAG AAGGAGAAGT TGAGACTAGA GCAGGCCCTG 
GAGGAAGCCC ACCAAGAGGG GAACAGAGGA GCCCGAACCA TTCACGACCT TAGAAATGAA 
GTTGAGAAAC TACGCAAGGA AGTGAGTGAG AGAGAGAAGG CTGTGGAAAA ACATTACAAG 
AGTCTTCCAG GTGAAAGCAA GACAAAGTTT CATACTCAAG AACAAGTGGT CAGAAGTCTG 
ACAGGCAGTG GCAGTCAGGA GGACCTGCTG CTTCAGAAAT CCAATGAAAA AGATTTGGAA 
GCAATACAGC AGAACTGCTA TTTAATGACT GCAGAGGAGC TCAAGTTTGG GAGCGATGGC 
TTAATAACAG AAAAGTGTTC TCAGCAGTCA CCAGACAGCA AACTCATCTT CTCCAAGGAA 
AAGCAACAAT CAGAGTATGA AGGGCTGACT GGGGACTTAA AAGCAGAACA GAACATCTAT 
GCCCATCTGG CAAAGACTCA GGACACAGAC AGTGTCAGCA ACCTGCAGGC TGAGCTGAAA 
GAGGTCCTTG CCCTTCGGAA GCAGCTGGAG CAGGATGTTC TTGCCTACCG GAACCTGCAG 
AAGGCCCTGC AGGAGCAGCT CAGTGAGATT CGGAGTCGAG AAGAAGAGCC GTTTTCATTT 
TATAGCGATC AAACATCGTA TCTGAGTATT TGCCTTGAAG AGCACAATCA GTTCCAATTG 
GAGCATTTTT CTCAAGAAGA ACTCAAGAAA AAGGTCAGTG ACCTCATACA GCTTGTGAAG 
GACCTGCACA CAGACAACCA GCACCTGAAG AAAACCATTT TTGATCTCTC TTCTGTGGGT 
TTCCAGGGAA GTGACAGACT TGAGTTAACA AAACAAGAAG AGCTTGTGGC TAGCAAGGAG 
GATGAGGACA CACTCAAATT TGAAGCGGAC GTTGAGACTC CTTTCCAGAG TGACCAGCAT 
TTGGAGCAAA GTCGTGAGAT CATGGAGGAC TATGCTGAGG GTGGCTGCAA AAGTGGATAT 
GGAAGGCACA TGGATTCCAA TATTTTAGGT CATGATGGGG CCCAAACTCC TGGTGCCTCT 
GAAGAGCACA CCCTAGAAGA TGAGCTCCTG GGCCTGCTTG CCACTCTCTT CAGTAAGAAG 
GCCACACCGT TGCTGGAATC CAGGCCAGAT CTTCTGAAAG CACTCGGTGC CCTACTTTTG 
GAACGCATAT GCTTGGCAGA GCAGGGTCGT CCTGGAGATC ACCTTGATAG TAAAACTGAG 
AAGGCACTTC AGCAAGTAGC TGTTCAGTTG AGAGATGAAC TTGGCCATTC CTTCCCTGCC 
AACTCGTTCT CCAAGTCATA CAATGAAGTC AAGTCAATGT GGGGAAATTG GCTGGTAAAG 
ACAGGAGACG AAGACACGGT GGAGCTGAAG AGTGTTTCAG TGCAGACCAT GGCCATAGAG 
GACACCCCGC ATGGATTCAA ACCTCAAAGC AAGAGAGATG CTTGGGCAGA GAAACAAGAA 
GAGGCCATTT TCAGCACTGA GCTTGAGTCA GAGGCGTTGG GTGAGATGCC AGGGCAACAG 
GCCACTCACC TCTCATTCCC CAGTGCCATC AACCCGGATG CCGAGAAGAC GGGCTTGTTG 
ATCCAATTAA AGACACCTGA GTTATTGGAA AATTTATATA ATCTTCCTGC TTCGCCAGAG 
GTGGTGGTGG CTCAACTCCA AGGCCAGGTT CTAGAGCTGC AGAGGGAGCT GAAAGAATTC 
AAAACCCGCA ACAAGCAACT CCATGAGAAG CTAATTCTGG CAGAGGCAAT GATGGAGGGG 
CTGCCGGTGC CCAACTCTGC GCTGGTGAAT GTGCCTGCAG CCCAGGCTGT TGTGAGAACA 
GCCTTCCAGG ACAACCCAGG CGAGCAAGAA GGACCTGAAA CCACACAGTC TGCTGGGAGA 
GACAAGGACA TGGACAGTGA CCAATATACA AGCTTTGAGA TCGATTCTGA AATCTGTCCA 
CCTGATGACC TTGCCTTATT ACCAGCATGC AAAGAGAATC TTGAAGACCT CCTAGGCCCA 
TCCTCCATAG CCACTTACCT GGATTCCAAG AGTCAGCTCT CTGTTAAAGT CAGCGTGAAT 
GGAACTGACC AGTCTGAGAA TATCAATATC CCTGATGACA CAGAAGACTT AAAACAGAAA 
ATCCACGACT TGCAAACCGA GCTGGAAGGC TACCGGAACA TCATTGTCCA GCTACTGAAG 
CACTCTCAGT GCAGTGAGGC TATTATCACA GTTTTGTGTG GGACAGAAGG GGCCCAAGAT 
GGCTTGAACA AGCCTAAGGG CCATATTGAT GAGGAAGAGA TGACATTTTC AAGTTTGCAC 
CAAGTACGAT ATGTGAAGCA TATGAAAATC CTCCGTCCAC TAACCCCGGA GATGATTGAT 
GGCAAGATGC TAGAGAGCCT CAAGCAGCAG CTGGTGGACC AGGAGCAGGA GCTACAGAAG 
GAGCAGGACT TGAACTTGGA ACTTTTCGGT GAAATCCATG ACCTGCAGAA CAAGTTCCAA 
GACCTCTCGC CATCAAGATA CGATTCATTG GTTCAGTCCC AAGCGAGGGA GCTCTCCCTT 
CAGCGACAGC AAATTAAGGA TAGCCATGGC ATCTGTGTCA TTTACCGTCA ACACATGAGC 
ACCATGATCA AGGCGTTTGA GGAGCTTCTG CAGGCCAGTG ATGTGGACAG TTGCGTGGCC 
GAGGGCTTCC GGGAGCAGCT GACACAGTGT GCTGGACTGC TAGAGCAACT GGAGAGGCTG 
TTTCTCCATG GAAAATCAGC CAGAGTGGAA CCACATCCCC AGAATGAACT GCTCAAGGGG 
TTAAGGACTG TGGAAGGCAA CTTACCCTAC CACCATCTCC TGCCTGAATC TCCTGAGCCT 
TCTGCCTCCC ATGCTCTGTC AGATGATGAA ATGTCTGAGA AGTCCTTCCT GTCTAGAGAC 
CCGAAGCCAG ACAGCGATAC TGAGAAGTAC CCAGCAATGG CGAGCCATTT TCCTCAAGAC 
TTACTAATGG AACACATACA GGAAATTCGA ACTTTGAGAA AGCATTTGGA AGAATCTATT 
AAAACAAATG AGAAGCTCCG GAAACAGCTG GAACGGCAGG GGTCTGAGAC TGACCAAGGC 
TCCAGAAATG TTTCTGCTTG TGGCTTAGCA CTGCACAGCT CTCTGACGTC AGAGATACAT 
TTCCTGAGGA AGCAGAACGA GGCCCTCAGT ATGATGCTCG AGAAGGGGTC CAAAGATAAA 
CAGAAAGAGA GTGAAAAATT ACGTGAGTCC CTGGCTAGGA AAGCTGAGAG TCTTGAGCAA 
CTTCAGCTAG AGTACACCAG TGTAAGGGAA GAAAATGAAA GGTTACAGAG AGACATCATT 
GAGAAGGAGA GACACAACCA GGAGCTGACT GAGGAGGTCT GCAGCAGCCG CCAGGAACTG 
AGCAGGGTGC AGGAAGAGGC GAAGTCAAGA CAGCAGCTGC TCTCACAGAA GGACAAGCTG 
CTTCAGTCCC TCCAAATGGA GCTCAAGGTG TATGAGAAAC TGGCCGAGGA ACATCCGAGG 
CTACAGCAAG ATGGCAGCAA ATGTCCTGAG GCCAGCGACA ATTCATTTGA TCTATTTGAA 
TCCACCCAGG CAATGGCACC TAAATCAGCT TCTGAGACTC CTCTGCTCTC AGGAACTGAT 
GTTGACTCGC TCTCCTGTGA CAGTACCAGT TCTGCCACCA GCCCTACTAG CATGCCCTGC 
CTGGTTGCTG GCCACCACAT GTGGGCCAGC AAGAGTGGCC ACCATATGCT GGGCCTGATT 
GAGGACTATG ATGCCCTCTA TAAGCAGATC AGCTGGGGCC AGACACTGCT TGCCAAGATG 
GATGTTCAAA CCCAAGAGGC TCTGAGCCCC ACAAGTCACA AGCTGGGACC AAAGGGTTCT 
TCATCCGTGC CTCTGAGCAA GTTTCTTTCC AGTATGAACA CAGCCAAGCT GGTCCTGGAA 
AAAGCATCCA GGTTGCTGAA GCTCTTCTGG AGGGTCTCAG TCCCCACCAA CGGCCAGTGT 
TCCCTTCACT GTGAGCAGAT TGGAGAAATG AAGGCAGAGA ACACGAAACT ACACAAAAAA 
TTGTTTGAAC AAGAAAAGAA GCTGCAGAAC ACAGCAAAAC TATTGCAGCA GAGCAAGCAC 
CAGGAGAAAG TCATCTTTGA TCAGTTGGTC ATCACCCACC AAGTCCTTCG GAAGGCCAGG 
GGAAACCTGG AGCTCAGGCC TGGGGCCACC CGTCCAGGAG CATCCAGTCC CAGCAGACCG 
GGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666102.2
CDS	169..5637
Translation	MDSGMEEEGALPGTLSGCSGLHPVLPSDLDVISDTSGLGNGVLPSMSEEKVSPTRARNMKDFENQITELKKENFNLKLRIYFLEERIQQEFAGPTEHIYKTNIELKVEVESLKRELQEKDQLLVKASKAVESLAERGGSEVQRVKEDARKKVQQVEDLLTKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEEWQKERNHFEERIQALQEDLREKEREIATEKKNNLKSYKAIQGLTMALKSKEREVEELDSKIKEVTTDSTKGREDPLKTQIPRFQLREGSEDCEAALVEKEALLAKLHSENVTKSTENHRLLRNVKKVTQELNDLKKEKLRLEQALEEAHQEGNRGARTIHDLRNEVEKLRKEVSEREKAVEKHYKSLPGESKTKFHTQEQVVRSLTGSGSQEDLLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGLITEKCSQQSPDSKLIFSKEKQQSEYEGLTGDLKAEQNIYAHLAKTQDTDSVSNLQAELKEVLALRKQLEQDVLAYRNLQKALQEQLSEIRSREEEPFSFYSDQTSYLSICLEEHNQFQLEHFSQEELKKKVSDLIQLVKDLHTDNQHLKKTIFDLSSVGFQGSDRLELTKQEELVASKEDEDTLKFEADVETPFQSDQHLEQSREIMEDYAEGGCKSGYGRHMDSNILGHDGAQTPGASEEHTLEDELLGLLATLFSKKATPLLESRPDLLKALGALLLERICLAEQGRPGDHLDSKTEKALQQVAVQLRDELGHSFPANSFSKSYNEVKSMWGNWLVKTGDEDTVELKSVSVQTMAIEDTPHGFKPQSKRDAWAEKQEEAIFSTELESEALGEMPGQQATHLSFPSAINPDAEKTGLLIQLKTPELLENLYNLPASPEVVVAQLQGQVLELQRELKEFKTRNKQLHEKLILAEAMMEGLPVPNSALVNVPAAQAVVRTAFQDNPGEQEGPETTQSAGRDKDMDSDQYTSFEIDSEICPPDDLALLPACKENLEDLLGPSSIATYLDSKSQLSVKVSVNGTDQSENINIPDDTEDLKQKIHDLQTELEGYRNIIVQLLKHSQCSEAIITVLCGTEGAQDGLNKPKGHIDEEEMTFSSLHQVRYVKHMKILRPLTPEMIDGKMLESLKQQLVDQEQELQKEQDLNLELFGEIHDLQNKFQDLSPSRYDSLVQSQARELSLQRQQIKDSHGICVIYRQHMSTMIKAFEELLQASDVDSCVAEGFREQLTQCAGLLEQLERLFLHGKSARVEPHPQNELLKGLRTVEGNLPYHHLLPESPEPSASHALSDDEMSEKSFLSRDPKPDSDTEKYPAMASHFPQDLLMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGSETDQGSRNVSACGLALHSSLTSEIHFLRKQNEALSMMLEKGSKDKQKESEKLRESLARKAESLEQLQLEYTSVREENERLQRDIIEKERHNQELTEEVCSSRQELSRVQEEAKSRQQLLSQKDKLLQSLQMELKVYEKLAEEHPRLQQDGSKCPEASDNSFDLFESTQAMAPKSASETPLLSGTDVDSLSCDSTSSATSPTSMPCLVAGHHMWASKSGHHMLGLIEDYDALYKQISWGQTLLAKMDVQTQEALSPTSHKLGPKGSSSVPLSKFLSSMNTAKLVLEKASRLLKLFWRVSVPTNGQCSLHCEQIGEMKAENTKLHKKLFEQEKKLQNTAKLLQQSKHQEKVIFDQLVITHQVLRKARGNLELRPGATRPGASSPSRPGS

Target ORF information:

RefSeq Version	NM_145990.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus CDK5 regulatory subunit associated protein 2 (Cdk5rap2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145990.4

ORF Insert Sequence:

ATGGACTCGG GGATGGAAGA GGAAGGCGCC CTGCCTGGGA CCCTCAGCGG TTGCAGTGGC 
CTTCACCCTG TTCTGCCAAG TGACCTGGAT GTCATCAGTG ACACTTCTGG CTTGGGAAAT 
GGAGTGCTCC CAAGCATGTC AGAAGAAAAG GTTTCTCCCA CCAGAGCCCG GAACATGAAG 
GACTTTGAAA ACCAAATCAC TGAGCTGAAG AAGGAGAACT TCAATCTAAA GCTCCGGATC 
TACTTCCTGG AGGAGAGAAT CCAGCAGGAG TTTGCTGGCC CCACCGAGCA CATCTACAAG 
ACGAACATTG AACTCAAGGT GGAAGTGGAA AGTCTGAAGC GCGAGCTCCA GGAGAAAGAT 
CAGTTGCTCG TCAAAGCCTC CAAAGCGGTG GAGAGCCTAG CAGAACGGGG TGGTTCTGAA 
GTCCAGCGGG TGAAAGAAGA TGCAAGGAAG AAGGTGCAGC AGGTGGAAGA CCTCCTAACG 
AAAAGGATAC ATCTTCTAGA AGAAGATGTG AAAGCCGCCC AGGCAGAACT GGAGAAGGCC 
TTTGCGGGGA CAGAAACAGA GAAGGCTCTT CGGCTCAGCT TAGAAAGCAA GCTCTCGGCG 
ATGAAGAAGA TGCAGGAGGG GGACCTGGAG ATGACTCTGG CTCTGGAAGA GAAGGACAGA 
CTGATTGAGG AGTTGAAGCT GTCTTTGAAG AGCAAAGAAG CTTTAATTCA GTGCCTTAAA 
GAGGAAAAAT CTCAGATGGC ATCTCCTGAC GAGAACGTGT CATCTGGAGA ACTCCGAGGA 
CTTTCTGCCA CTCTGAGGGA AGAAAAAGAG AGAGACGCTG AGGAATGGCA GAAGGAGAGA 
AACCACTTTG AAGAGAGGAT CCAGGCACTT CAGGAGGACC TGAGAGAGAA GGAAAGAGAA 
ATTGCTACAG AGAAGAAAAA TAACTTAAAG AGTTATAAAG CCATTCAGGG TCTAACCATG 
GCATTAAAAT CAAAGGAAAG AGAGGTTGAA GAACTTGATT CCAAAATCAA AGAGGTCACT 
ACGGACTCCA CCAAAGGCAG AGAGGATCCC TTAAAAACCC AGATCCCCAG ATTCCAGCTA 
AGAGAGGGGT CTGAGGACTG TGAAGCTGCG CTGGTAGAGA AGGAAGCCCT ATTGGCCAAG 
CTACACTCAG AAAATGTCAC AAAGAGCACT GAGAACCATA GGTTGCTCAG GAATGTTAAA 
AAGGTCACCC AGGAGTTGAA TGACTTGAAG AAGGAGAAGT TGAGACTAGA GCAGGCCCTG 
GAGGAAGCCC ACCAAGAGGG GAACAGAGGA GCCCGAACCA TTCACGACCT TAGAAATGAA 
GTTGAGAAAC TACGCAAGGA AGTGAGTGAG AGAGAGAAGG CTGTGGAAAA ACATTACAAG 
AGTCTTCCAG GTGAAAGCAA GACAAAGTTT CATACTCAAG AACAAGTGGT CAGAAGTCTG 
ACAGGCAGTG GCAGTCAGGA GGACCTGCTG CTTCAGAAAT CCAATGAAAA AGATTTGGAA 
GCAATACAGC AGAACTGCTA TTTAATGACT GCAGAGGAGC TCAAGTTTGG GAGCGATGGC 
TTAATAACAG AAAAGTGTTC TCAGCAGTCA CCAGACAGCA AACTCATCTT CTCCAAGGAA 
AAGCAACAAT CAGAGTATGA AGGGCTGACT GGGGACTTAA AAGCAGAACA GAACATCTAT 
GCCCATCTGG CAAAGACTCA GGACACAGAC AGTGTCAGCA ACCTGCAGGC TGAGCTGAAA 
GAGGTCCTTG CCCTTCGGAA GCAGCTGGAG CAGGATGTTC TTGCCTACCG GAACCTGCAG 
AAGGCCCTGC AGGAGCAGCT CAGTGAGATT CGGAGTCGAG AAGAAGAGCC GTTTTCATTT 
TATAGCGATC AAACATCGTA TCTGAGTATT TGCCTTGAAG AGCACAATCA GTTCCAATTG 
GAGCATTTTT CTCAAGAAGA ACTCAAGAAA AAGGTCAGTG ACCTCATACA GCTTGTGAAG 
GACCTGCACA CAGACAACCA GCACCTGAAG AAAACCATTT TTGATCTCTC TTCTGTGGGT 
TTCCAGGGAA GTGACAGACT TGAGTTAACA AAACAAGAAG AGCTTGTGGC TAGCAAGGAG 
GATGAGGACA CACTCAAATT TGAAGCGGAC GTTGAGACTC CTTTCCAGAG TGACCAGCAT 
TTGGAGCAAA GTCGTGAGAT CATGGAGGAC TATGCTGAGG GTGGCTGCAA AAGTGGATAT 
GGAAGGCACA TGGATTCCAA TATTTTAGGT CATGATGGGG CCCAAACTCC TGGTGCCTCT 
GAAGAGCACA CCCTAGAAGA TGAGCTCCTG GGCCTGCTTG CCACTCTCTT CAGTAAGAAG 
GCCACACCGT TGCTGGAATC CAGGCCAGAT CTTCTGAAAG CACTCGGTGC CCTACTTTTG 
GAACGCATAT GCTTGGCAGA GCAGGGTCGT CCTGGAGATC ACCTTGATAG TAAAACTGAG 
AAGGCACTTC AGCAAGTAGC TGTTCAGTTG AGAGATGAAC TTGGCCATTC CTTCCCTGCC 
AACTCGTTCT CCAAGTCATA CAATGAAGTC AAGTCAATGT GGGGAAATTG GCTGGTAAAG 
ACAGGAGACG AAGACACGGT GGAGCTGAAG AGTGTTTCAG TGCAGACCAT GGCCATAGAG 
GACACCCCGC ATGGATTCAA ACCTCAAAGC AAGAGAGATG CTTGGGCAGA GAAACAAGAA 
GAGGCCATTT TCAGCACTGA GCTTGAGTCA GAGGCGTTGG GTGAGATGCC AGGGCAACAG 
GCCACTCACC TCTCATTCCC CAGTGCCATC AACCCGGATG CCGAGAAGAC GGGCTTGTTG 
ATCCAATTAA AGACACCTGA GTTATTGGAA AATTTATATA ATCTTCCTGC TTCGCCAGAG 
GTGGTGGTGG CTCAACTCCA AGGCCAGGTT CTAGAGCTGC AGAGGGAGCT GAAAGAATTC 
AAAACCCGCA ACAAGCAACT CCATGAGAAG CTAATTCTGG CAGAGGCAAT GATGGAGGGG 
CTGCCGGTGC CCAACTCTGC GCTGGTGAAT GTGCCTGCAG CCCAGGCTGT TGTGAGAACA 
GCCTTCCAGG ACAACCCAGG CGAGCAAGAA GGACCTGAAA CCACACAGTC TGCTGGGAGA 
GACAAGGACA TGGACAGTGA CCAATATACA AGCTTTGAGA TCGATTCTGA AATCTGTCCA 
CCTGATGACC TTGCCTTATT ACCAGCATGC AAAGAGAATC TTGAAGACCT CCTAGGCCCA 
TCCTCCATAG CCACTTACCT GGATTCCAAG AGTCAGCTCT CTGTTAAAGT CAGCGTGAAT 
GGAACTGACC AGTCTGAGAA TATCAATATC CCTGATGACA CAGAAGACTT AAAACAGAAA 
ATCCACGACT TGCAAACCGA GCTGGAAGGC TACCGGAACA TCATTGTCCA GCTACTGAAG 
CACTCTCAGT GCAGTGAGGC TATTATCACA GTTTTGTGTG GGACAGAAGG GGCCCAAGAT 
GGCTTGAACA AGCCTAAGGG CCATATTGAT GAGGAAGAGA TGACATTTTC AAGTTTGCAC 
CAAGTACGAT ATGTGAAGCA TATGAAAATC CTCCGTCCAC TAACCCCGGA GATGATTGAT 
GGCAAGATGC TAGAGAGCCT CAAGCAGCAG CTGGTGGACC AGGAGCAGGA GCTACAGAAG 
GAGCAGGACT TGAACTTGGA ACTTTTCGGT GAAATCCATG ACCTGCAGAA CAAGTTCCAA 
GACCTCTCGC CATCAAGATA CGATTCATTG GTTCAGTCCC AAGCGAGGGA GCTCTCCCTT 
CAGCGACAGC AAATTAAGGA TAGCCATGGC ATCTGTGTCA TTTACCGTCA ACACATGAGC 
ACCATGATCA AGGCGTTTGA GGAGCTTCTG CAGGCCAGTG ATGTGGACAG TTGCGTGGCC 
GAGGGCTTCC GGGAGCAGCT GACACAGTGT GCTGGACTGC TAGAGCAACT GGAGAGGCTG 
TTTCTCCATG GAAAATCAGC CAGAGTGGAA CCACATCCCC AGAATGAACT GCTCAAGGGG 
TTAAGGACTG TGGAAGGCAA CTTACCCTAC CACCATCTCC TGCCTGAATC TCCTGAGCCT 
TCTGCCTCCC ATGCTCTGTC AGATGATGAA ATGTCTGAGA AGTCCTTCCT GTCTAGAGAC 
CCGAAGCCAG ACAGCGATAC TGAGAAGTAC CCAGCAATGG CGAGCCATTT TCCTCAAGAC 
TTACTAATGG AACACATACA GGAAATTCGA ACTTTGAGAA AGCATTTGGA AGAATCTATT 
AAAACAAATG AGAAGCTCCG GAAACAGCTG GAACGGCAGG GGTCTGAGAC TGACCAAGGC 
TCCAGAAATG TTTCTGCTTG TGGCTTAGCA CTGCACAGCT CTCTGACGTC AGAGATACAT 
TTCCTGAGGA AGCAGAACGA GGCCCTCAGT ATGATGCTCG AGAAGGGGTC CAAAGATAAA 
CAGAAAGAGA GTGAAAAATT ACGTGAGTCC CTGGCTAGGA AAGCTGAGAG TCTTGAGCAA 
CTTCAGCTAG AGTACACCAG TGTAAGGGAA GAAAATGAAA GGTTACAGAG AGACATCATT 
GAGAAGGAGA GACACAACCA GGAGCTGACT GAGGAGGTCT GCAGCAGCCG CCAGGAACTG 
AGCAGGGTGC AGGAAGAGGC GAAGTCAAGA CAGCAGCTGC TCTCACAGAA GGACAAGCTG 
CTTCAGTCCC TCCAAATGGA GCTCAAGGTG TATGAGAAAC TGGCCGAGGA ACATCCGAGG 
CTACAGCAAG ATGGCAGCAA ATGTCCTGAG GCCAGCGACA ATTCATTTGA TCTATTTGAA 
TCCACCCAGG CAATGGCACC TAAATCAGCT TCTGAGACTC CTCTGCTCTC AGGAACTGAT 
GTTGACTCGC TCTCCTGTGA CAGTACCAGT TCTGCCACCA GCCCTACTAG CATGCCCTGC 
CTGGTTGCTG GCCACCACAT GTGGGCCAGC AAGAGTGGCC ACCATATGCT GGGCCTGATT 
GAGGACTATG ATGCCCTCTA TAAGCAGATC AGCTGGGGCC AGACACTGCT TGCCAAGATG 
GATGTTCAAA CCCAAGAGGC TCTGAGCCCC ACAAGTCACA AGCTGGGACC AAAGGGTTCT 
TCATCCGTGC CTCTGAGCAA GTTTCTTTCC AGTATGAACA CAGCCAAGCT GGTCCTGGAA 
AAAGCATCCA GGTTGCTGAA GCTCTTCTGG AGGGTCTCAG TCCCCACCAA CGGCCAGTGT 
TCCCTTCACT GTGAGCAGAT TGGAGAAATG AAGGCAGAGA ACACGAAACT ACACAAAAAA 
TTGTTTGAAC AAGAAAAGAA GCTGCAGAAC ACAGCAAAAC TATTGCAGCA GAGCAAGCAC 
CAGGAGAAAG TCATCTTTGA TCAGTTGGTC ATCACCCACC AAGTCCTTCG GAAGGCCAGG 
GGAAACCTGG AGCTCAGGCC TGGGGCCACC CGTCCAGGAG CATCCAGTCC CAGCAGACCG 
GGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdk5rap2 ( NM_001313762.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001300691.1 Mus musculus CDK5 regulatory subunit associated protein 2 (Cdk5rap2), transcript variant 2, mRNA.

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CloneID	OMu32821
Clone ID Related Accession (Same CDS sequence)	NM_001313762.1
Accession Version	NM_001313762.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	CDK5 regulatory subunit-associated protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF738512.1, BC079888.1 and AL929409.5. On Sep 1, 2015 this sequence version replaced XM_006537749.2. Transcript Variant: This variant (2) lacks three exons in the 5' region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079888.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGA TGCAGGAGGG GGACCTGGAG ATGACTCTGG CTCTGGAAGA GAAGGACAGA 
CTGATTGAGG AGTTGAAGCT GTCTTTGAAG AGCAAAGAAG CTTTAATTCA GTGCCTTAAA 
GAGGAAAAAT CTCAGATGGC ATCTCCTGAC GAGAACGTGT CATCTGGAGA ACTCCGAGGA 
CTTTCTGCCA CTCTGAGGGA AGAAAAAGAG AGAGACGCTG AGGAATGGCA GAAGGAGAGA 
AACCACTTTG AAGAGAGGAT CCAGGCACTT CAGGAGGACC TGAGAGAGAA GGAAAGAGAA 
ATTGCTACAG AGAAGAAAAA TAACTTAAAG AGTTATAAAG CCATTCAGGG TCTAACCATG 
GCATTAAAAT CAAAGGAAAG AGAGGTTGAA GAACTTGATT CCAAAATCAA AGAGGTCACT 
ACGGACTCCA CCAAAGGCAG AGAGGATCCC TTAAAAACCC AGATCCCCAG ATTCCAGCTA 
AGAGAGGACC TTAGAAATGA AGTTGAGAAA CTACGCAAGG AAGTGAGTGA GAGAGAGAAG 
GCTGTGGAAA AACATTACAA GAGTCTTCCA GGTGAAAGCA AGACAAAGTT TCATACTCAA 
GAACAAGTGG TCAGAAGTCT GACAGGCAGT GGCAGTCAGG AGGACCTGCT GCTTCAGAAA 
TCCAATGAAA AAGATTTGGA AGCAATACAG CAGAACTGCT ATTTAATGAC TGCAGAGGAG 
CTCAAGTTTG GGAGCGATGG CTTAATAACA GAAAAGTGTT CTCAGCAGTC ACCAGACAGC 
AAACTCATCT TCTCCAAGGA AAAGCAACAA TCAGAGTATG AAGGGCTGAC TGGGGACTTA 
AAAGCAGAAC AGAACATCTA TGCCCATCTG GCAAAGACTC AGGACACAGA CAGTGTCAGC 
AACCTGCAGG CTGAGCTGAA AGAGGTCCTT GCCCTTCGGA AGCAGCTGGA GCAGGATGTT 
CTTGCCTACC GGAACCTGCA GAAGGCCCTG CAGGAGCAGC TCAGTGAGAT TCGGAGTCGA 
GAAGAAGAGC CGTTTTCATT TTATAGCGAT CAAACATCGT ATCTGAGTAT TTGCCTTGAA 
GAGCACAATC AGTTCCAATT GGAGCATTTT TCTCAAGAAG AACTCAAGAA AAAGGTCAGT 
GACCTCATAC AGCTTGTGAA GGACCTGCAC ACAGACAACC AGCACCTGAA GAAAACCATT 
TTTGATCTCT CTTCTGTGGG TTTCCAGGGA AGTGACAGAC TTGAGTTAAC AAAACAAGAA 
GAGCTTGTGG CTAGCAAGGA GGATGAGGAC ACACTCAAAT TTGAAGCGGA CGTTGAGACT 
CCTTTCCAGA GTGACCAGCA TTTGGAGCAA AGTCGTGAGA TCATGGAGGA CTATGCTGAG 
GGTGGCTGCA AAAGTGGATA TGGAAGGCAC ATGGATTCCA ATATTTTAGG TCATGATGGG 
GCCCAAACTC CTGGTGCCTC TGAAGAGCAC ACCCTAGAAG ATGAGCTCCT GGGCCTGCTT 
GCCACTCTCT TCAGTAAGAA GGCCACACCG TTGCTGGAAT CCAGGCCAGA TCTTCTGAAA 
GCACTCGGTG CCCTACTTTT GGAACGCATA TGCTTGGCAG AGCAGGGTCG TCCTGGAGAT 
CACCTTGATA GTAAAACTGA GAAGGCACTT CAGCAAGTAG CTGTTCAGTT GAGAGATGAA 
CTTGGCCATT CCTTCCCTGC CAACTCGTTC TCCAAGTCAT ACAATGAAGT CAAGTCAATG 
TGGGGAAATT GGCTGGTAAA GACAGGAGAC GAAGACACGG TGGAGCTGAA GAGTGTTTCA 
GTGCAGACCA TGGCCATAGA GGACACCCCG CATGGATTCA AACCTCAAAG CAAGAGAGAT 
GCTTGGGCAG AGAAACAAGA AGAGGCCATT TTCAGCACTG AGCTTGAGTC AGAGGCGTTG 
GGTGAGATGC CAGGGCAACA GGCCACTCAC CTCTCATTCC CCAGTGCCAT CAACCCGGAT 
GCCGAGAAGA CGGGCTTGTT GATCCAATTA AAGACACCTG AGTTATTGGA AAATTTATAT 
AATCTTCCTG CTTCGCCAGA GGTGGTGGTG GCTCAACTCC AAGGCCAGGT TCTAGAGCTG 
CAGAGGGAGC TGAAAGAATT CAAAACCCGC AACAAGCAAC TCCATGAGAA GCTAATTCTG 
GCAGAGGCAA TGATGGAGGG GCTGCCGGTG CCCAACTCTG CGCTGGTGAA TGTGCCTGCA 
GCCCAGGCTG TTGTGAGAAC AGCCTTCCAG GACAACCCAG GCGAGCAAGA AGGACCTGAA 
ACCACACAGT CTGCTGGGAG AGACAAGGAC ATGGACAGTG ACCAATATAC AAGCTTTGAG 
ATCGATTCTG AAATCTGTCC ACCTGATGAC CTTGCCTTAT TACCAGCATG CAAAGAGAAT 
CTTGAAGACC TCCTAGGCCC ATCCTCCATA GCCACTTACC TGGATTCCAA GAGTCAGCTC 
TCTGTTAAAG TCAGCGTGAA TGGAACTGAC CAGTCTGAGA ATATCAATAT CCCTGATGAC 
ACAGAAGACT TAAAACAGAA AATCCACGAC TTGCAAACCG AGCTGGAAGG CTACCGGAAC 
ATCATTGTCC AGCTACTGAA GCACTCTCAG TGCAGTGAGG CTATTATCAC AGTTTTGTGT 
GGGACAGAAG GGGCCCAAGA TGGCTTGAAC AAGCCTAAGG GCCATATTGA TGAGGAAGAG 
ATGACATTTT CAAGTTTGCA CCAAGTACGA TATGTGAAGC ATATGAAAAT CCTCCGTCCA 
CTAACCCCGG AGATGATTGA TGGCAAGATG CTAGAGAGCC TCAAGCAGCA GCTGGTGGAC 
CAGGAGCAGG AGCTACAGAA GGAGCAGGAC TTGAACTTGG AACTTTTCGG TGAAATCCAT 
GACCTGCAGA ACAAGTTCCA AGACCTCTCG CCATCAAGAT ACGATTCATT GGTTCAGTCC 
CAAGCGAGGG AGCTCTCCCT TCAGCGACAG CAAATTAAGG ATAGCCATGG CATCTGTGTC 
ATTTACCGTC AACACATGAG CACCATGATC AAGGCGTTTG AGGAGCTTCT GCAGGCCAGT 
GATGTGGACA GTTGCGTGGC CGAGGGCTTC CGGGAGCAGC TGACACAGTG TGCTGGACTG 
CTAGAGCAAC TGGAGAGGCT GTTTCTCCAT GGAAAATCAG CCAGAGTGGA ACCACATCCC 
CAGAATGAAC TGCTCAAGGG GTTAAGGACT GTGGAAGGCA ACTTACCCTA CCACCATCTC 
CTGCCTGAAT CTCCTGAGCC TTCTGCCTCC CATGCTCTGT CAGATGATGA AATGTCTGAG 
AAGTCCTTCC TGTCTAGAGA CCCGAAGCCA GACAGCGATA CTGAGAAGTA CCCAGCAATG 
GCGAGCCATT TTCCTCAAGA CTTACTAATG GAACACATAC AGGAAATTCG AACTTTGAGA 
AAGCATTTGG AAGAATCTAT TAAAACAAAT GAGAAGCTCC GGAAACAGCT GGAACGGCAG 
GGGTCTGAGA CTGACCAAGG CTCCAGAAAT GTTTCTGCTT GTGGCTTAGC ACTGCACAGC 
TCTCTGACGT CAGAGATACA TTTCCTGAGG AAGCAGAACG AGGCCCTCAG TATGATGCTC 
GAGAAGGGGT CCAAAGATAA ACAGAAAGAG AGTGAAAAAT TACGTGAGTC CCTGGCTAGG 
AAAGCTGAGA GTCTTGAGCA ACTTCAGCTA GAGTACACCA GTGTAAGGGA AGAAAATGAA 
AGGTTACAGA GAGACATCAT TGAGAAGGAG AGACACAACC AGGAGCTGAC TGAGGAGGTC 
TGCAGCAGCC GCCAGGAACT GAGCAGGGTG CAGGAAGAGG CGAAGTCAAG ACAGCAGCTG 
CTCTCACAGA AGGACAAGCT GCTTCAGTCC CTCCAAATGG AGCTCAAGGT GTATGAGAAA 
CTGGCCGAGG AACATCCGAG GCTACAGCAA GATGGCAGCA AATGTCCTGA GGCCAGCGAC 
AATTCATTTG ATCTATTTGA ATCCACCCAG GCAATGGCAC CTAAATCAGC TTCTGAGACT 
CCTCTGCTCT CAGGAACTGA TGTTGACTCG CTCTCCTGTG ACAGTACCAG TTCTGCCACC 
AGCCCTACTA GCATGCCCTG CCTGGTTGCT GGCCACCACA TGTGGGCCAG CAAGAGTGGC 
CACCATATGC TGGGCCTGAT TGAGGACTAT GATGCCCTCT ATAAGCAGAT CAGCTGGGGC 
CAGACACTGC TTGCCAAGAT GGATGTTCAA ACCCAAGAGG CTCTGAGCCC CACAAGTCAC 
AAGCTGGGAC CAAAGGGTTC TTCATCCGTG CCTCTGAGCA AGTTTCTTTC CAGTATGAAC 
ACAGCCAAGC TGGTCCTGGA AAAAGCATCC AGGTTGCTGA AGCTCTTCTG GAGGGTCTCA 
GTCCCCACCA ACGGCCAGTG TTCCCTTCAC TGTGAGCAGA TTGGAGAAAT GAAGGCAGAG 
AACACGAAAC TACACAAAAA ATTGTTTGAA CAAGAAAAGA AGCTGCAGAA CACAGCAAAA 
CTATTGCAGC AGAGCAAGCA CCAGGAGAAA GTCATCTTTG ATCAGTTGGT CATCACCCAC 
CAAGTCCTTC GGAAGGCCAG GGGAAACCTG GAGCTCAGGC CTGGGGCCAC CCGTCCAGGA 
GCATCCAGTC CCAGCAGACC GGGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001300691.1
CDS	581..5230
Translation	MKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEEWQKERNHFEERIQALQEDLREKEREIATEKKNNLKSYKAIQGLTMALKSKEREVEELDSKIKEVTTDSTKGREDPLKTQIPRFQLREDLRNEVEKLRKEVSEREKAVEKHYKSLPGESKTKFHTQEQVVRSLTGSGSQEDLLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGLITEKCSQQSPDSKLIFSKEKQQSEYEGLTGDLKAEQNIYAHLAKTQDTDSVSNLQAELKEVLALRKQLEQDVLAYRNLQKALQEQLSEIRSREEEPFSFYSDQTSYLSICLEEHNQFQLEHFSQEELKKKVSDLIQLVKDLHTDNQHLKKTIFDLSSVGFQGSDRLELTKQEELVASKEDEDTLKFEADVETPFQSDQHLEQSREIMEDYAEGGCKSGYGRHMDSNILGHDGAQTPGASEEHTLEDELLGLLATLFSKKATPLLESRPDLLKALGALLLERICLAEQGRPGDHLDSKTEKALQQVAVQLRDELGHSFPANSFSKSYNEVKSMWGNWLVKTGDEDTVELKSVSVQTMAIEDTPHGFKPQSKRDAWAEKQEEAIFSTELESEALGEMPGQQATHLSFPSAINPDAEKTGLLIQLKTPELLENLYNLPASPEVVVAQLQGQVLELQRELKEFKTRNKQLHEKLILAEAMMEGLPVPNSALVNVPAAQAVVRTAFQDNPGEQEGPETTQSAGRDKDMDSDQYTSFEIDSEICPPDDLALLPACKENLEDLLGPSSIATYLDSKSQLSVKVSVNGTDQSENINIPDDTEDLKQKIHDLQTELEGYRNIIVQLLKHSQCSEAIITVLCGTEGAQDGLNKPKGHIDEEEMTFSSLHQVRYVKHMKILRPLTPEMIDGKMLESLKQQLVDQEQELQKEQDLNLELFGEIHDLQNKFQDLSPSRYDSLVQSQARELSLQRQQIKDSHGICVIYRQHMSTMIKAFEELLQASDVDSCVAEGFREQLTQCAGLLEQLERLFLHGKSARVEPHPQNELLKGLRTVEGNLPYHHLLPESPEPSASHALSDDEMSEKSFLSRDPKPDSDTEKYPAMASHFPQDLLMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGSETDQGSRNVSACGLALHSSLTSEIHFLRKQNEALSMMLEKGSKDKQKESEKLRESLARKAESLEQLQLEYTSVREENERLQRDIIEKERHNQELTEEVCSSRQELSRVQEEAKSRQQLLSQKDKLLQSLQMELKVYEKLAEEHPRLQQDGSKCPEASDNSFDLFESTQAMAPKSASETPLLSGTDVDSLSCDSTSSATSPTSMPCLVAGHHMWASKSGHHMLGLIEDYDALYKQISWGQTLLAKMDVQTQEALSPTSHKLGPKGSSSVPLSKFLSSMNTAKLVLEKASRLLKLFWRVSVPTNGQCSLHCEQIGEMKAENTKLHKKLFEQEKKLQNTAKLLQQSKHQEKVIFDQLVITHQVLRKARGNLELRPGATRPGASSPSRPGS

Target ORF information:

RefSeq Version	NM_001313762.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus CDK5 regulatory subunit associated protein 2 (Cdk5rap2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001313762.1

ORF Insert Sequence:

ATGAAGAAGA TGCAGGAGGG GGACCTGGAG ATGACTCTGG CTCTGGAAGA GAAGGACAGA 
CTGATTGAGG AGTTGAAGCT GTCTTTGAAG AGCAAAGAAG CTTTAATTCA GTGCCTTAAA 
GAGGAAAAAT CTCAGATGGC ATCTCCTGAC GAGAACGTGT CATCTGGAGA ACTCCGAGGA 
CTTTCTGCCA CTCTGAGGGA AGAAAAAGAG AGAGACGCTG AGGAATGGCA GAAGGAGAGA 
AACCACTTTG AAGAGAGGAT CCAGGCACTT CAGGAGGACC TGAGAGAGAA GGAAAGAGAA 
ATTGCTACAG AGAAGAAAAA TAACTTAAAG AGTTATAAAG CCATTCAGGG TCTAACCATG 
GCATTAAAAT CAAAGGAAAG AGAGGTTGAA GAACTTGATT CCAAAATCAA AGAGGTCACT 
ACGGACTCCA CCAAAGGCAG AGAGGATCCC TTAAAAACCC AGATCCCCAG ATTCCAGCTA 
AGAGAGGACC TTAGAAATGA AGTTGAGAAA CTACGCAAGG AAGTGAGTGA GAGAGAGAAG 
GCTGTGGAAA AACATTACAA GAGTCTTCCA GGTGAAAGCA AGACAAAGTT TCATACTCAA 
GAACAAGTGG TCAGAAGTCT GACAGGCAGT GGCAGTCAGG AGGACCTGCT GCTTCAGAAA 
TCCAATGAAA AAGATTTGGA AGCAATACAG CAGAACTGCT ATTTAATGAC TGCAGAGGAG 
CTCAAGTTTG GGAGCGATGG CTTAATAACA GAAAAGTGTT CTCAGCAGTC ACCAGACAGC 
AAACTCATCT TCTCCAAGGA AAAGCAACAA TCAGAGTATG AAGGGCTGAC TGGGGACTTA 
AAAGCAGAAC AGAACATCTA TGCCCATCTG GCAAAGACTC AGGACACAGA CAGTGTCAGC 
AACCTGCAGG CTGAGCTGAA AGAGGTCCTT GCCCTTCGGA AGCAGCTGGA GCAGGATGTT 
CTTGCCTACC GGAACCTGCA GAAGGCCCTG CAGGAGCAGC TCAGTGAGAT TCGGAGTCGA 
GAAGAAGAGC CGTTTTCATT TTATAGCGAT CAAACATCGT ATCTGAGTAT TTGCCTTGAA 
GAGCACAATC AGTTCCAATT GGAGCATTTT TCTCAAGAAG AACTCAAGAA AAAGGTCAGT 
GACCTCATAC AGCTTGTGAA GGACCTGCAC ACAGACAACC AGCACCTGAA GAAAACCATT 
TTTGATCTCT CTTCTGTGGG TTTCCAGGGA AGTGACAGAC TTGAGTTAAC AAAACAAGAA 
GAGCTTGTGG CTAGCAAGGA GGATGAGGAC ACACTCAAAT TTGAAGCGGA CGTTGAGACT 
CCTTTCCAGA GTGACCAGCA TTTGGAGCAA AGTCGTGAGA TCATGGAGGA CTATGCTGAG 
GGTGGCTGCA AAAGTGGATA TGGAAGGCAC ATGGATTCCA ATATTTTAGG TCATGATGGG 
GCCCAAACTC CTGGTGCCTC TGAAGAGCAC ACCCTAGAAG ATGAGCTCCT GGGCCTGCTT 
GCCACTCTCT TCAGTAAGAA GGCCACACCG TTGCTGGAAT CCAGGCCAGA TCTTCTGAAA 
GCACTCGGTG CCCTACTTTT GGAACGCATA TGCTTGGCAG AGCAGGGTCG TCCTGGAGAT 
CACCTTGATA GTAAAACTGA GAAGGCACTT CAGCAAGTAG CTGTTCAGTT GAGAGATGAA 
CTTGGCCATT CCTTCCCTGC CAACTCGTTC TCCAAGTCAT ACAATGAAGT CAAGTCAATG 
TGGGGAAATT GGCTGGTAAA GACAGGAGAC GAAGACACGG TGGAGCTGAA GAGTGTTTCA 
GTGCAGACCA TGGCCATAGA GGACACCCCG CATGGATTCA AACCTCAAAG CAAGAGAGAT 
GCTTGGGCAG AGAAACAAGA AGAGGCCATT TTCAGCACTG AGCTTGAGTC AGAGGCGTTG 
GGTGAGATGC CAGGGCAACA GGCCACTCAC CTCTCATTCC CCAGTGCCAT CAACCCGGAT 
GCCGAGAAGA CGGGCTTGTT GATCCAATTA AAGACACCTG AGTTATTGGA AAATTTATAT 
AATCTTCCTG CTTCGCCAGA GGTGGTGGTG GCTCAACTCC AAGGCCAGGT TCTAGAGCTG 
CAGAGGGAGC TGAAAGAATT CAAAACCCGC AACAAGCAAC TCCATGAGAA GCTAATTCTG 
GCAGAGGCAA TGATGGAGGG GCTGCCGGTG CCCAACTCTG CGCTGGTGAA TGTGCCTGCA 
GCCCAGGCTG TTGTGAGAAC AGCCTTCCAG GACAACCCAG GCGAGCAAGA AGGACCTGAA 
ACCACACAGT CTGCTGGGAG AGACAAGGAC ATGGACAGTG ACCAATATAC AAGCTTTGAG 
ATCGATTCTG AAATCTGTCC ACCTGATGAC CTTGCCTTAT TACCAGCATG CAAAGAGAAT 
CTTGAAGACC TCCTAGGCCC ATCCTCCATA GCCACTTACC TGGATTCCAA GAGTCAGCTC 
TCTGTTAAAG TCAGCGTGAA TGGAACTGAC CAGTCTGAGA ATATCAATAT CCCTGATGAC 
ACAGAAGACT TAAAACAGAA AATCCACGAC TTGCAAACCG AGCTGGAAGG CTACCGGAAC 
ATCATTGTCC AGCTACTGAA GCACTCTCAG TGCAGTGAGG CTATTATCAC AGTTTTGTGT 
GGGACAGAAG GGGCCCAAGA TGGCTTGAAC AAGCCTAAGG GCCATATTGA TGAGGAAGAG 
ATGACATTTT CAAGTTTGCA CCAAGTACGA TATGTGAAGC ATATGAAAAT CCTCCGTCCA 
CTAACCCCGG AGATGATTGA TGGCAAGATG CTAGAGAGCC TCAAGCAGCA GCTGGTGGAC 
CAGGAGCAGG AGCTACAGAA GGAGCAGGAC TTGAACTTGG AACTTTTCGG TGAAATCCAT 
GACCTGCAGA ACAAGTTCCA AGACCTCTCG CCATCAAGAT ACGATTCATT GGTTCAGTCC 
CAAGCGAGGG AGCTCTCCCT TCAGCGACAG CAAATTAAGG ATAGCCATGG CATCTGTGTC 
ATTTACCGTC AACACATGAG CACCATGATC AAGGCGTTTG AGGAGCTTCT GCAGGCCAGT 
GATGTGGACA GTTGCGTGGC CGAGGGCTTC CGGGAGCAGC TGACACAGTG TGCTGGACTG 
CTAGAGCAAC TGGAGAGGCT GTTTCTCCAT GGAAAATCAG CCAGAGTGGA ACCACATCCC 
CAGAATGAAC TGCTCAAGGG GTTAAGGACT GTGGAAGGCA ACTTACCCTA CCACCATCTC 
CTGCCTGAAT CTCCTGAGCC TTCTGCCTCC CATGCTCTGT CAGATGATGA AATGTCTGAG 
AAGTCCTTCC TGTCTAGAGA CCCGAAGCCA GACAGCGATA CTGAGAAGTA CCCAGCAATG 
GCGAGCCATT TTCCTCAAGA CTTACTAATG GAACACATAC AGGAAATTCG AACTTTGAGA 
AAGCATTTGG AAGAATCTAT TAAAACAAAT GAGAAGCTCC GGAAACAGCT GGAACGGCAG 
GGGTCTGAGA CTGACCAAGG CTCCAGAAAT GTTTCTGCTT GTGGCTTAGC ACTGCACAGC 
TCTCTGACGT CAGAGATACA TTTCCTGAGG AAGCAGAACG AGGCCCTCAG TATGATGCTC 
GAGAAGGGGT CCAAAGATAA ACAGAAAGAG AGTGAAAAAT TACGTGAGTC CCTGGCTAGG 
AAAGCTGAGA GTCTTGAGCA ACTTCAGCTA GAGTACACCA GTGTAAGGGA AGAAAATGAA 
AGGTTACAGA GAGACATCAT TGAGAAGGAG AGACACAACC AGGAGCTGAC TGAGGAGGTC 
TGCAGCAGCC GCCAGGAACT GAGCAGGGTG CAGGAAGAGG CGAAGTCAAG ACAGCAGCTG 
CTCTCACAGA AGGACAAGCT GCTTCAGTCC CTCCAAATGG AGCTCAAGGT GTATGAGAAA 
CTGGCCGAGG AACATCCGAG GCTACAGCAA GATGGCAGCA AATGTCCTGA GGCCAGCGAC 
AATTCATTTG ATCTATTTGA ATCCACCCAG GCAATGGCAC CTAAATCAGC TTCTGAGACT 
CCTCTGCTCT CAGGAACTGA TGTTGACTCG CTCTCCTGTG ACAGTACCAG TTCTGCCACC 
AGCCCTACTA GCATGCCCTG CCTGGTTGCT GGCCACCACA TGTGGGCCAG CAAGAGTGGC 
CACCATATGC TGGGCCTGAT TGAGGACTAT GATGCCCTCT ATAAGCAGAT CAGCTGGGGC 
CAGACACTGC TTGCCAAGAT GGATGTTCAA ACCCAAGAGG CTCTGAGCCC CACAAGTCAC 
AAGCTGGGAC CAAAGGGTTC TTCATCCGTG CCTCTGAGCA AGTTTCTTTC CAGTATGAAC 
ACAGCCAAGC TGGTCCTGGA AAAAGCATCC AGGTTGCTGA AGCTCTTCTG GAGGGTCTCA 
GTCCCCACCA ACGGCCAGTG TTCCCTTCAC TGTGAGCAGA TTGGAGAAAT GAAGGCAGAG 
AACACGAAAC TACACAAAAA ATTGTTTGAA CAAGAAAAGA AGCTGCAGAA CACAGCAAAA 
CTATTGCAGC AGAGCAAGCA CCAGGAGAAA GTCATCTTTG ATCAGTTGGT CATCACCCAC 
CAAGTCCTTC GGAAGGCCAG GGGAAACCTG GAGCTCAGGC CTGGGGCCAC CCGTCCAGGA 
GCATCCAGTC CCAGCAGACC GGGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Molecular biology of the cell28(5)587-599(2017 Mar)
Gao FJ,Shi L,Hines T,Hebbar S,Neufeld KL,Smith DS

CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development.
Stem cell reports8(2)198-204(2017 02)
Zaqout S,Bessa P,Kr?mer N,Stoltenburg-Didinger G,Kaindl AM

Divergent regulation of functionally distinct ?-tubulin complexes during differentiation.
The Journal of cell biology213(6)679-92(2016 Jun)
Muroyama A,Seldin L,Lechler T

Species-Specific Expression of Full-Length and Alternatively Spliced Variant Forms of CDK5RAP2.
PloS one10(11)e0142577(2015)
Park JS,Lee MK,Kang S,Jin Y,Fu S,Rosales JL,Lee KY

Novel Alternative Splice Variants of Mouse Cdk5rap2.
PloS one10(8)e0136684(2015)
Kraemer N,Issa-Jahns L,Neubert G,Ravindran E,Mani S,Ninnemann O,Kaindl AM

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Cdk5rap2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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