Ocrl cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Ocrl
Entrez Gene ID	320634
Full Name	OCRL, inositol polyphosphate-5-phosphatase
Synonyms	9530014D17Rik,BB143339,OCRL1
General protein information	Preferred Names OCRL, inositol polyphosphate-5-phosphatase Names inositol polyphosphate 5-phosphatase OCRL-1 oculocerebrorenal syndrome of Lowe
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X A5

mRNA and Protein(s)

mRNA	Protein	Name
XM_011251008.2	XP_011249310.1	inositol polyphosphate 5-phosphatase OCRL-1 isoform X1
NM_177215.3	NP_796189.2	inositol polyphosphate 5-phosphatase OCRL
XM_017318524.2	XP_017174013.1	inositol polyphosphate 5-phosphatase OCRL-1 isoform X2
XM_017318524.1	XP_017174013.1	inositol polyphosphate 5-phosphatase OCRL-1 isoform X2
XM_011251008.3	XP_011249310.1	inositol polyphosphate 5-phosphatase OCRL-1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	OCRL	NP_000267.2
Pan troglodytes (chimpanzee)	OCRL	XP_003317719.2
Rattus norvegicus (Norway rat)	Ocrl	NP_001101726.2
Canis lupus familiaris (dog)	OCRL	XP_852376.2
Mus musculus (house mouse)	Ocrl	NP_796189.2
Xenopus tropicalis (tropical clawed frog)	ocrl	XP_004919252.1
Gallus gallus (chicken)	OCRL	XP_004940632.1
Danio rerio (zebrafish)	LOC100329312	XP_003199958.1
	OCRL	XP_002806438.1
Danio rerio (zebrafish)	ocrl	NP_001071232.1
Drosophila melanogaster (fruit fly)	Ocrl	NP_569962.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010556	XP_558090.3
Bos taurus (cattle)	OCRL	NP_001095661.1

Gene Ontology
Bibliography

Related articles in PubMed

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.
Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ
Developmental cell43(3)318-331.e5(2017 11)

Kidney Tubular Ablation of
Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, De Camilli P, Ishibe S
Journal of the American Society of Nephrology : JASN28(5)1399-1407(2017 May)

Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development.
Zhu S, Dai J, Liu H, Cong X, Chen Y, Wu Y, Hu H, Heng BC, Ouyang HW, Zhou Y
Arthritis & rheumatology (Hoboken, N.J.)67(8)2154-63(2015 May)

Primary cilia signaling mediates intraocular pressure sensation.
Luo N, Conwell MD, Chen X, Kettenhofen CI, Westlake CJ, Cantor LB, Wells CD, Weinreb RN, Corson TW, Spandau DF, Joos KM, Iomini C, Obukhov AG, Sun Y
Proceedings of the National Academy of Sciences of the United States of America111(35)12871-6(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that the functions of OCRL/INPP5B and proton-chloride exchange transporter 5 converge on shared mechanisms, the impairment of which has a dramatic effect on proximal tubule endocytosis
Title: Kidney Tubular Ablation of

OCRL mRNA and protein were downregulated in osteoarthritis knee cartilage. OCRL inhibits Rac1 activation in OA.
Title: Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development.

Implications of OCRL and TRPV4 in primary cilia function may also shed light on mechanosensation in other organ systems.
Title: Primary cilia signaling mediates intraocular pressure sensation.

Bcl10 was required to locally deliver the vesicular OCRL phosphatase that regulates PI(4,5)P(2) and F-actin turnover, both crucial for the completion of phagosome closure.
Title: The NF-?B signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles.

These results indicate a functional overlap of Ocrl and Inpp5b in most cell lineages, especially in extraembryonic tissues.
Title: X-inactivation analysis of embryonic lethality in Ocrl wt/-; Inpp5b-/- mice.

The following Ocrl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ocrl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06080	NM_177215.3 Latest version!	Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
OMu74679	XM_011251008.3 Latest version!	Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu83139	XM_017318524.2 Latest version!	Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OMu83139	XM_017318524.1	Mus musculus oculocerebrorenal syndrome of Lowe (Ocrl), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu74679	XM_011251008.2	Mus musculus oculocerebrorenal syndrome of Lowe (Ocrl), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ocrl ( XM_011251008.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011249310.1 Mus musculus oculocerebrorenal syndrome of Lowe (Ocrl), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu74679
Clone ID Related Accession (Same CDS sequence)	XM_011251008.2 , XM_011251008.3
Accession Version	XM_011251008.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2700bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate 5-phosphatase OCRL-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011251008.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGC AGAAGAAACT CTTTTGATTG ATATTGCTTC AAACAGTGGC 
TGCAAAATTC GGGTACAGGG AGACTGGACC AGAGAGCGCC ACTTTGAAAT TCCTGATGAA 
GAACGCTGTT TGAAGTTCCT CTCAGAGGTC CTCGAAGCTC AGGAAGCTCA GTCACAGCTT 
CTTGTTCCAG AACAAAAAGA CTCATCTAGC TGGTACCAGA AATTAGACAC TATGGATAAA 
CCTGCTTATT CAGGGCTGCT TGGATTTGAG GATAATTTTT CATCTCTGGA TTTAGATAAG 
AAAATGAATA CACAAAATCC CCGATCAGGG AGTCATCGGG AACCACCCCC TCCACCTTCT 
TCATCGACTA GAATGCTTTC GCGTGAAAAG GAAGCTTCAA ACAAAGAACA GCCCAAAGTG 
ACCAATACCA TGCGGAAGCT ATTTGTCCCG AACACCCAAA CCGGGCAGCG AGAGGGTCTC 
ATTAAACATA TCCTCACAAA GCGAGAGAAA GAATATGTCA ACATCCAGTC TTTCAGGTTT 
TTTGTTGGAA CTTGGAATGT GAACGGCCAG TCTCCAGACA GCAGCTTAGA ACCTTGGCTC 
GACTGTGATC CAAATCCTCC TGATATTTAC TGCATTGGAT TCCAAGAGCT GGACTTGAGC 
ACCGAAGCCT TTTTCTACTT CGAGTCTGTG AAAGAGCAAG AGTGGTCCTT GGCTGTGGAA 
AGGGGGCTGC CTTCGAAGGC CAAGTATAGA AAAGTTCAAC TGGTCCGCCT TGTGGGGATG 
ATGCTTCTTA TATTTGCCAG AAAAGATCAG TGTCAATACA TCCGAGATGT TGCTACAGAA 
ACAACTGGAA CTGGAATCAT GGGGAAAATG GGAAACAAAG GTGGGGTAGC TGTAAGATTT 
GTATTCCACA ACACCACTTT CTGCATTGTC AATTCGCACC TGGCCGCCCA CGTGGAAGAG 
TTCGAACGAA GGAATCAGGA TTATAAAGAC ATCTGTGCAA GAATGACTTT TTCAGTCCCC 
AATCAGACTG TCCCGCAAGT GAACATCATG AAGCATGATG TTGTCATTTG GCTGGGAGAC 
TTGAACTACA GACTTTGCAT GCCTGATGCC AGTGAGGTGA AAAGTCTTAT TAATAAAAAT 
GAGCTTCATA AGCTGTTGAA ATTTGACCAG TTAAACATTC AGCGCACACA GAAAAAAGCT 
TTTGCGGATT TCAATGAAGG GGAAATTAAT TTCGTTCCCA CGTACAAATA TGATTCGAAA 
ACTGACAGAT GGGATTCCAG TGGGAAATGC CGAGTTCCCG CCTGGTGTGA CCGAATTCTT 
TGGAGAGGAA TAAATGTTAA TCAACTTCAT TACCGGAGTC ACATGGAACT CAAAACTAGT 
GACCACAAAC CTGTTAGCGC CCTGTTCCAT ATTGGGGTGA AGGTTGTGGA TGAGCGGAGG 
TATCGGAAGG TCTTTGAAGA TATCGTCCGC ATTATGGACA GAATGGAAAA CGACTTCCTT 
CCTTCATTAG AACTTAGCAG GAGAGAGTTT TTTTTTGAGA ATGTGAAGTT TCGGCAGCTG 
CAAAAGGAGA AGTTCCAGAT CAGCAACAAT GGACAGGTTC CCTGCCATTT TTCTTTCATC 
CCTAAGCTTA ATGACAGCCA ATACTGCAAG CCATGGCTTC GAGCTGAACC TTTTGAGGGC 
TACTTGGAGC CAAACGAGAC CTTAGACATC TCCCTTGATG TATACGTCAG CAAAGACTCT 
GTAACCATCC TGAACTCCGG TGAAGATAAG ATTGAAGATA TTCTTGTCCT CCATTTGGAT 
CGAGGCAAAG ATTACTTCTT GACCATCGGT GGGAATTACC TCCCAAGTTG CTTTGGAACC 
TCATTGGAGG CTTTGTGCCG AATGAAAAGA CCAATTCGAG AAGTTCCTGT CACCAAACTC 
ATAGACCTGG AAGAAGACAG CTACCTAGAA AAGGAGAAAT CCCTTCTGCA GATGGTACCC 
TTGGATGAAG GTACCAGTGA GCGACCCCTT CAAGTCCCCA AAGAGATCTG GCTTCTAGTA 
GATCACTTGT TCAAATATGC ATGTCACCAG GAGGACTTGT TCCAAACCCC TGGAATGCAG 
GAGGAGTTAC AGCAGATCAT TGATTGCCTG GATACCAGCA TTCCTGAGAC AATTCCTGGC 
AATAACCATT CTGTGGCTGA AGCACTGCTC ATTTTCCTGG AAGCTCTGCC AGAGCCAGTC 
ATCTGTTATG AGCTGTATCA GCGATGTCTT GACTCTGCTC ATGATCCTCG GATCTGCAAA 
CAGGTCATTT CCCAGCTTCC AAGGTGCCAT AGAAATGTTT TCCGCTACTT GATGGCATTC 
CTTCGTGAAC TCTTAAAATT CTCTGACTAC AACAATATCA ACACCAACAT GATTGCTACC 
CTGTTCAGTA GCCTTCTCCT AAGACCTCCA CCAAACCTCA TGACAAGACA GACTCCAAAT 
GACCGCCAGC ATGCCATCCA GTTCCTCTTG GTCTTCCTGC TTGGGAACGA GGAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011249310.1
CDS	253..2952
Translation	MEPRLPIGAQPLAMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKDSSSWYQKLDTMDKPAYSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSYLEKEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED

Target ORF information:

RefSeq Version	XM_011251008.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus oculocerebrorenal syndrome of Lowe (Ocrl), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011251008.2

ORF Insert Sequence:

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGC AGAAGAAACT CTTTTGATTG ATATTGCTTC AAACAGTGGC 
TGCAAAATTC GGGTACAGGG AGACTGGACC AGAGAGCGCC ACTTTGAAAT TCCTGATGAA 
GAACGCTGTT TGAAGTTCCT CTCAGAGGTC CTCGAAGCTC AGGAAGCTCA GTCACAGCTT 
CTTGTTCCAG AACAAAAAGA CTCATCTAGC TGGTACCAGA AATTAGACAC TATGGATAAA 
CCTGCTTATT CAGGGCTGCT TGGATTTGAG GATAATTTTT CATCTCTGGA TTTAGATAAG 
AAAATGAATA CACAAAATCC CCGATCAGGG AGTCATCGGG AACCACCCCC TCCACCTTCT 
TCATCGACTA GAATGCTTTC GCGTGAAAAG GAAGCTTCAA ACAAAGAACA GCCCAAAGTG 
ACCAATACCA TGCGGAAGCT ATTTGTCCCG AACACCCAAA CCGGGCAGCG AGAGGGTCTC 
ATTAAACATA TCCTCACAAA GCGAGAGAAA GAATATGTCA ACATCCAGTC TTTCAGGTTT 
TTTGTTGGAA CTTGGAATGT GAACGGCCAG TCTCCAGACA GCAGCTTAGA ACCTTGGCTC 
GACTGTGATC CAAATCCTCC TGATATTTAC TGCATTGGAT TCCAAGAGCT GGACTTGAGC 
ACCGAAGCCT TTTTCTACTT CGAGTCTGTG AAAGAGCAAG AGTGGTCCTT GGCTGTGGAA 
AGGGGGCTGC CTTCGAAGGC CAAGTATAGA AAAGTTCAAC TGGTCCGCCT TGTGGGGATG 
ATGCTTCTTA TATTTGCCAG AAAAGATCAG TGTCAATACA TCCGAGATGT TGCTACAGAA 
ACAACTGGAA CTGGAATCAT GGGGAAAATG GGAAACAAAG GTGGGGTAGC TGTAAGATTT 
GTATTCCACA ACACCACTTT CTGCATTGTC AATTCGCACC TGGCCGCCCA CGTGGAAGAG 
TTCGAACGAA GGAATCAGGA TTATAAAGAC ATCTGTGCAA GAATGACTTT TTCAGTCCCC 
AATCAGACTG TCCCGCAAGT GAACATCATG AAGCATGATG TTGTCATTTG GCTGGGAGAC 
TTGAACTACA GACTTTGCAT GCCTGATGCC AGTGAGGTGA AAAGTCTTAT TAATAAAAAT 
GAGCTTCATA AGCTGTTGAA ATTTGACCAG TTAAACATTC AGCGCACACA GAAAAAAGCT 
TTTGCGGATT TCAATGAAGG GGAAATTAAT TTCGTTCCCA CGTACAAATA TGATTCGAAA 
ACTGACAGAT GGGATTCCAG TGGGAAATGC CGAGTTCCCG CCTGGTGTGA CCGAATTCTT 
TGGAGAGGAA TAAATGTTAA TCAACTTCAT TACCGGAGTC ACATGGAACT CAAAACTAGT 
GACCACAAAC CTGTTAGCGC CCTGTTCCAT ATTGGGGTGA AGGTTGTGGA TGAGCGGAGG 
TATCGGAAGG TCTTTGAAGA TATCGTCCGC ATTATGGACA GAATGGAAAA CGACTTCCTT 
CCTTCATTAG AACTTAGCAG GAGAGAGTTT TTTTTTGAGA ATGTGAAGTT TCGGCAGCTG 
CAAAAGGAGA AGTTCCAGAT CAGCAACAAT GGACAGGTTC CCTGCCATTT TTCTTTCATC 
CCTAAGCTTA ATGACAGCCA ATACTGCAAG CCATGGCTTC GAGCTGAACC TTTTGAGGGC 
TACTTGGAGC CAAACGAGAC CTTAGACATC TCCCTTGATG TATACGTCAG CAAAGACTCT 
GTAACCATCC TGAACTCCGG TGAAGATAAG ATTGAAGATA TTCTTGTCCT CCATTTGGAT 
CGAGGCAAAG ATTACTTCTT GACCATCGGT GGGAATTACC TCCCAAGTTG CTTTGGAACC 
TCATTGGAGG CTTTGTGCCG AATGAAAAGA CCAATTCGAG AAGTTCCTGT CACCAAACTC 
ATAGACCTGG AAGAAGACAG CTACCTAGAA AAGGAGAAAT CCCTTCTGCA GATGGTACCC 
TTGGATGAAG GTACCAGTGA GCGACCCCTT CAAGTCCCCA AAGAGATCTG GCTTCTAGTA 
GATCACTTGT TCAAATATGC ATGTCACCAG GAGGACTTGT TCCAAACCCC TGGAATGCAG 
GAGGAGTTAC AGCAGATCAT TGATTGCCTG GATACCAGCA TTCCTGAGAC AATTCCTGGC 
AATAACCATT CTGTGGCTGA AGCACTGCTC ATTTTCCTGG AAGCTCTGCC AGAGCCAGTC 
ATCTGTTATG AGCTGTATCA GCGATGTCTT GACTCTGCTC ATGATCCTCG GATCTGCAAA 
CAGGTCATTT CCCAGCTTCC AAGGTGCCAT AGAAATGTTT TCCGCTACTT GATGGCATTC 
CTTCGTGAAC TCTTAAAATT CTCTGACTAC AACAATATCA ACACCAACAT GATTGCTACC 
CTGTTCAGTA GCCTTCTCCT AAGACCTCCA CCAAACCTCA TGACAAGACA GACTCCAAAT 
GACCGCCAGC ATGCCATCCA GTTCCTCTTG GTCTTCCTGC TTGGGAACGA GGAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ocrl ( NM_177215.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_796189.2 Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), mRNA.

Price & Availability↑

CloneID	OMu06080
Clone ID Related Accession (Same CDS sequence)	NM_177215.3
Accession Version	NM_177215.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2703bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-10
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate 5-phosphatase OCRL
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC068146.1. On Apr 5, 2004 this sequence version replaced NM_177215.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068146.1, AK041963.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGA AGCAGAAGAA ACTCTTTTGA TTGATATTGC TTCAAACAGT 
GGCTGCAAAA TTCGGGTACA GGGAGACTGG ACCAGAGAGC GCCACTTTGA AATTCCTGAT 
GAAGAACGCT GTTTGAAGTT CCTCTCAGAG GTCCTCGAAG CTCAGGAAGC TCAGTCACAG 
CTTCTTGTTC CAGAACAAAA AGACTCATCT AGCTGGTACC AGAAATTAGA CACTATGGAT 
AAACCTGCTT ATTCAGGGCT GCTTGGATTT GAGGATAATT TTTCATCTCT GGATTTAGAT 
AAGAAAATGA ATACACAAAA TCCCCGATCA GGGAGTCATC GGGAACCACC CCCTCCACCT 
TCTTCATCGA CTAGAATGCT TTCGCGTGAA AAGGAAGCTT CAAACAAAGA ACAGCCCAAA 
GTGACCAATA CCATGCGGAA GCTATTTGTC CCGAACACCC AAACCGGGCA GCGAGAGGGT 
CTCATTAAAC ATATCCTCAC AAAGCGAGAG AAAGAATATG TCAACATCCA GTCTTTCAGG 
TTTTTTGTTG GAACTTGGAA TGTGAACGGC CAGTCTCCAG ACAGCAGCTT AGAACCTTGG 
CTCGACTGTG ATCCAAATCC TCCTGATATT TACTGCATTG GATTCCAAGA GCTGGACTTG 
AGCACCGAAG CCTTTTTCTA CTTCGAGTCT GTGAAAGAGC AAGAGTGGTC CTTGGCTGTG 
GAAAGGGGGC TGCCTTCGAA GGCCAAGTAT AGAAAAGTTC AACTGGTCCG CCTTGTGGGG 
ATGATGCTTC TTATATTTGC CAGAAAAGAT CAGTGTCAAT ACATCCGAGA TGTTGCTACA 
GAAACAACTG GAACTGGAAT CATGGGGAAA ATGGGAAACA AAGGTGGGGT AGCTGTAAGA 
TTTGTATTCC ACAACACCAC TTTCTGCATT GTCAATTCGC ACCTGGCCGC CCACGTGGAA 
GAGTTCGAAC GAAGGAATCA GGATTATAAA GACATCTGTG CAAGAATGAC TTTTTCAGTC 
CCCAATCAGA CTGTCCCGCA AGTGAACATC ATGAAGCATG ATGTTGTCAT TTGGCTGGGA 
GACTTGAACT ACAGACTTTG CATGCCTGAT GCCAGTGAGG TGAAAAGTCT TATTAATAAA 
AATGAGCTTC ATAAGCTGTT GAAATTTGAC CAGTTAAACA TTCAGCGCAC ACAGAAAAAA 
GCTTTTGCGG ATTTCAATGA AGGGGAAATT AATTTCGTTC CCACGTACAA ATATGATTCG 
AAAACTGACA GATGGGATTC CAGTGGGAAA TGCCGAGTTC CCGCCTGGTG TGACCGAATT 
CTTTGGAGAG GAATAAATGT TAATCAACTT CATTACCGGA GTCACATGGA ACTCAAAACT 
AGTGACCACA AACCTGTTAG CGCCCTGTTC CATATTGGGG TGAAGGTTGT GGATGAGCGG 
AGGTATCGGA AGGTCTTTGA AGATATCGTC CGCATTATGG ACAGAATGGA AAACGACTTC 
CTTCCTTCAT TAGAACTTAG CAGGAGAGAG TTTTTTTTTG AGAATGTGAA GTTTCGGCAG 
CTGCAAAAGG AGAAGTTCCA GATCAGCAAC AATGGACAGG TTCCCTGCCA TTTTTCTTTC 
ATCCCTAAGC TTAATGACAG CCAATACTGC AAGCCATGGC TTCGAGCTGA ACCTTTTGAG 
GGCTACTTGG AGCCAAACGA GACCTTAGAC ATCTCCCTTG ATGTATACGT CAGCAAAGAC 
TCTGTAACCA TCCTGAACTC CGGTGAAGAT AAGATTGAAG ATATTCTTGT CCTCCATTTG 
GATCGAGGCA AAGATTACTT CTTGACCATC GGTGGGAATT ACCTCCCAAG TTGCTTTGGA 
ACCTCATTGG AGGCTTTGTG CCGAATGAAA AGACCAATTC GAGAAGTTCC TGTCACCAAA 
CTCATAGACC TGGAAGAAGA CAGCTACCTA GAAAAGGAGA AATCCCTTCT GCAGATGGTA 
CCCTTGGATG AAGGTACCAG TGAGCGACCC CTTCAAGTCC CCAAAGAGAT CTGGCTTCTA 
GTAGATCACT TGTTCAAATA TGCATGTCAC CAGGAGGACT TGTTCCAAAC CCCTGGAATG 
CAGGAGGAGT TACAGCAGAT CATTGATTGC CTGGATACCA GCATTCCTGA GACAATTCCT 
GGCAATAACC ATTCTGTGGC TGAAGCACTG CTCATTTTCC TGGAAGCTCT GCCAGAGCCA 
GTCATCTGTT ATGAGCTGTA TCAGCGATGT CTTGACTCTG CTCATGATCC TCGGATCTGC 
AAACAGGTCA TTTCCCAGCT TCCAAGGTGC CATAGAAATG TTTTCCGCTA CTTGATGGCA 
TTCCTTCGTG AACTCTTAAA ATTCTCTGAC TACAACAATA TCAACACCAA CATGATTGCT 
ACCCTGTTCA GTAGCCTTCT CCTAAGACCT CCACCAAACC TCATGACAAG ACAGACTCCA 
AATGACCGCC AGCATGCCAT CCAGTTCCTC TTGGTCTTCC TGCTTGGGAA CGAGGAAGAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_796189.2
CDS	198..2900
Translation	MEPRLPIGAQPLAMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKDSSSWYQKLDTMDKPAYSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSYLEKEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED

Target ORF information:

RefSeq Version	NM_177215.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177215.3

ORF Insert Sequence:

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGA AGCAGAAGAA ACTCTTTTGA TTGATATTGC TTCAAACAGT 
GGCTGCAAAA TTCGGGTACA GGGAGACTGG ACCAGAGAGC GCCACTTTGA AATTCCTGAT 
GAAGAACGCT GTTTGAAGTT CCTCTCAGAG GTCCTCGAAG CTCAGGAAGC TCAGTCACAG 
CTTCTTGTTC CAGAACAAAA AGACTCATCT AGCTGGTACC AGAAATTAGA CACTATGGAT 
AAACCTGCTT ATTCAGGGCT GCTTGGATTT GAGGATAATT TTTCATCTCT GGATTTAGAT 
AAGAAAATGA ATACACAAAA TCCCCGATCA GGGAGTCATC GGGAACCACC CCCTCCACCT 
TCTTCATCGA CTAGAATGCT TTCGCGTGAA AAGGAAGCTT CAAACAAAGA ACAGCCCAAA 
GTGACCAATA CCATGCGGAA GCTATTTGTC CCGAACACCC AAACCGGGCA GCGAGAGGGT 
CTCATTAAAC ATATCCTCAC AAAGCGAGAG AAAGAATATG TCAACATCCA GTCTTTCAGG 
TTTTTTGTTG GAACTTGGAA TGTGAACGGC CAGTCTCCAG ACAGCAGCTT AGAACCTTGG 
CTCGACTGTG ATCCAAATCC TCCTGATATT TACTGCATTG GATTCCAAGA GCTGGACTTG 
AGCACCGAAG CCTTTTTCTA CTTCGAGTCT GTGAAAGAGC AAGAGTGGTC CTTGGCTGTG 
GAAAGGGGGC TGCCTTCGAA GGCCAAGTAT AGAAAAGTTC AACTGGTCCG CCTTGTGGGG 
ATGATGCTTC TTATATTTGC CAGAAAAGAT CAGTGTCAAT ACATCCGAGA TGTTGCTACA 
GAAACAACTG GAACTGGAAT CATGGGGAAA ATGGGAAACA AAGGTGGGGT AGCTGTAAGA 
TTTGTATTCC ACAACACCAC TTTCTGCATT GTCAATTCGC ACCTGGCCGC CCACGTGGAA 
GAGTTCGAAC GAAGGAATCA GGATTATAAA GACATCTGTG CAAGAATGAC TTTTTCAGTC 
CCCAATCAGA CTGTCCCGCA AGTGAACATC ATGAAGCATG ATGTTGTCAT TTGGCTGGGA 
GACTTGAACT ACAGACTTTG CATGCCTGAT GCCAGTGAGG TGAAAAGTCT TATTAATAAA 
AATGAGCTTC ATAAGCTGTT GAAATTTGAC CAGTTAAACA TTCAGCGCAC ACAGAAAAAA 
GCTTTTGCGG ATTTCAATGA AGGGGAAATT AATTTCGTTC CCACGTACAA ATATGATTCG 
AAAACTGACA GATGGGATTC CAGTGGGAAA TGCCGAGTTC CCGCCTGGTG TGACCGAATT 
CTTTGGAGAG GAATAAATGT TAATCAACTT CATTACCGGA GTCACATGGA ACTCAAAACT 
AGTGACCACA AACCTGTTAG CGCCCTGTTC CATATTGGGG TGAAGGTTGT GGATGAGCGG 
AGGTATCGGA AGGTCTTTGA AGATATCGTC CGCATTATGG ACAGAATGGA AAACGACTTC 
CTTCCTTCAT TAGAACTTAG CAGGAGAGAG TTTTTTTTTG AGAATGTGAA GTTTCGGCAG 
CTGCAAAAGG AGAAGTTCCA GATCAGCAAC AATGGACAGG TTCCCTGCCA TTTTTCTTTC 
ATCCCTAAGC TTAATGACAG CCAATACTGC AAGCCATGGC TTCGAGCTGA ACCTTTTGAG 
GGCTACTTGG AGCCAAACGA GACCTTAGAC ATCTCCCTTG ATGTATACGT CAGCAAAGAC 
TCTGTAACCA TCCTGAACTC CGGTGAAGAT AAGATTGAAG ATATTCTTGT CCTCCATTTG 
GATCGAGGCA AAGATTACTT CTTGACCATC GGTGGGAATT ACCTCCCAAG TTGCTTTGGA 
ACCTCATTGG AGGCTTTGTG CCGAATGAAA AGACCAATTC GAGAAGTTCC TGTCACCAAA 
CTCATAGACC TGGAAGAAGA CAGCTACCTA GAAAAGGAGA AATCCCTTCT GCAGATGGTA 
CCCTTGGATG AAGGTACCAG TGAGCGACCC CTTCAAGTCC CCAAAGAGAT CTGGCTTCTA 
GTAGATCACT TGTTCAAATA TGCATGTCAC CAGGAGGACT TGTTCCAAAC CCCTGGAATG 
CAGGAGGAGT TACAGCAGAT CATTGATTGC CTGGATACCA GCATTCCTGA GACAATTCCT 
GGCAATAACC ATTCTGTGGC TGAAGCACTG CTCATTTTCC TGGAAGCTCT GCCAGAGCCA 
GTCATCTGTT ATGAGCTGTA TCAGCGATGT CTTGACTCTG CTCATGATCC TCGGATCTGC 
AAACAGGTCA TTTCCCAGCT TCCAAGGTGC CATAGAAATG TTTTCCGCTA CTTGATGGCA 
TTCCTTCGTG AACTCTTAAA ATTCTCTGAC TACAACAATA TCAACACCAA CATGATTGCT 
ACCCTGTTCA GTAGCCTTCT CCTAAGACCT CCACCAAACC TCATGACAAG ACAGACTCCA 
AATGACCGCC AGCATGCCAT CCAGTTCCTC TTGGTCTTCC TGCTTGGGAA CGAGGAAGAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ocrl ( XM_011251008.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011249310.1 Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu74679
Clone ID Related Accession (Same CDS sequence)	XM_011251008.2 , XM_011251008.3
Accession Version	XM_011251008.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2700bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate 5-phosphatase OCRL-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011251008.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGC AGAAGAAACT CTTTTGATTG ATATTGCTTC AAACAGTGGC 
TGCAAAATTC GGGTACAGGG AGACTGGACC AGAGAGCGCC ACTTTGAAAT TCCTGATGAA 
GAACGCTGTT TGAAGTTCCT CTCAGAGGTC CTCGAAGCTC AGGAAGCTCA GTCACAGCTT 
CTTGTTCCAG AACAAAAAGA CTCATCTAGC TGGTACCAGA AATTAGACAC TATGGATAAA 
CCTGCTTATT CAGGGCTGCT TGGATTTGAG GATAATTTTT CATCTCTGGA TTTAGATAAG 
AAAATGAATA CACAAAATCC CCGATCAGGG AGTCATCGGG AACCACCCCC TCCACCTTCT 
TCATCGACTA GAATGCTTTC GCGTGAAAAG GAAGCTTCAA ACAAAGAACA GCCCAAAGTG 
ACCAATACCA TGCGGAAGCT ATTTGTCCCG AACACCCAAA CCGGGCAGCG AGAGGGTCTC 
ATTAAACATA TCCTCACAAA GCGAGAGAAA GAATATGTCA ACATCCAGTC TTTCAGGTTT 
TTTGTTGGAA CTTGGAATGT GAACGGCCAG TCTCCAGACA GCAGCTTAGA ACCTTGGCTC 
GACTGTGATC CAAATCCTCC TGATATTTAC TGCATTGGAT TCCAAGAGCT GGACTTGAGC 
ACCGAAGCCT TTTTCTACTT CGAGTCTGTG AAAGAGCAAG AGTGGTCCTT GGCTGTGGAA 
AGGGGGCTGC CTTCGAAGGC CAAGTATAGA AAAGTTCAAC TGGTCCGCCT TGTGGGGATG 
ATGCTTCTTA TATTTGCCAG AAAAGATCAG TGTCAATACA TCCGAGATGT TGCTACAGAA 
ACAACTGGAA CTGGAATCAT GGGGAAAATG GGAAACAAAG GTGGGGTAGC TGTAAGATTT 
GTATTCCACA ACACCACTTT CTGCATTGTC AATTCGCACC TGGCCGCCCA CGTGGAAGAG 
TTCGAACGAA GGAATCAGGA TTATAAAGAC ATCTGTGCAA GAATGACTTT TTCAGTCCCC 
AATCAGACTG TCCCGCAAGT GAACATCATG AAGCATGATG TTGTCATTTG GCTGGGAGAC 
TTGAACTACA GACTTTGCAT GCCTGATGCC AGTGAGGTGA AAAGTCTTAT TAATAAAAAT 
GAGCTTCATA AGCTGTTGAA ATTTGACCAG TTAAACATTC AGCGCACACA GAAAAAAGCT 
TTTGCGGATT TCAATGAAGG GGAAATTAAT TTCGTTCCCA CGTACAAATA TGATTCGAAA 
ACTGACAGAT GGGATTCCAG TGGGAAATGC CGAGTTCCCG CCTGGTGTGA CCGAATTCTT 
TGGAGAGGAA TAAATGTTAA TCAACTTCAT TACCGGAGTC ACATGGAACT CAAAACTAGT 
GACCACAAAC CTGTTAGCGC CCTGTTCCAT ATTGGGGTGA AGGTTGTGGA TGAGCGGAGG 
TATCGGAAGG TCTTTGAAGA TATCGTCCGC ATTATGGACA GAATGGAAAA CGACTTCCTT 
CCTTCATTAG AACTTAGCAG GAGAGAGTTT TTTTTTGAGA ATGTGAAGTT TCGGCAGCTG 
CAAAAGGAGA AGTTCCAGAT CAGCAACAAT GGACAGGTTC CCTGCCATTT TTCTTTCATC 
CCTAAGCTTA ATGACAGCCA ATACTGCAAG CCATGGCTTC GAGCTGAACC TTTTGAGGGC 
TACTTGGAGC CAAACGAGAC CTTAGACATC TCCCTTGATG TATACGTCAG CAAAGACTCT 
GTAACCATCC TGAACTCCGG TGAAGATAAG ATTGAAGATA TTCTTGTCCT CCATTTGGAT 
CGAGGCAAAG ATTACTTCTT GACCATCGGT GGGAATTACC TCCCAAGTTG CTTTGGAACC 
TCATTGGAGG CTTTGTGCCG AATGAAAAGA CCAATTCGAG AAGTTCCTGT CACCAAACTC 
ATAGACCTGG AAGAAGACAG CTACCTAGAA AAGGAGAAAT CCCTTCTGCA GATGGTACCC 
TTGGATGAAG GTACCAGTGA GCGACCCCTT CAAGTCCCCA AAGAGATCTG GCTTCTAGTA 
GATCACTTGT TCAAATATGC ATGTCACCAG GAGGACTTGT TCCAAACCCC TGGAATGCAG 
GAGGAGTTAC AGCAGATCAT TGATTGCCTG GATACCAGCA TTCCTGAGAC AATTCCTGGC 
AATAACCATT CTGTGGCTGA AGCACTGCTC ATTTTCCTGG AAGCTCTGCC AGAGCCAGTC 
ATCTGTTATG AGCTGTATCA GCGATGTCTT GACTCTGCTC ATGATCCTCG GATCTGCAAA 
CAGGTCATTT CCCAGCTTCC AAGGTGCCAT AGAAATGTTT TCCGCTACTT GATGGCATTC 
CTTCGTGAAC TCTTAAAATT CTCTGACTAC AACAATATCA ACACCAACAT GATTGCTACC 
CTGTTCAGTA GCCTTCTCCT AAGACCTCCA CCAAACCTCA TGACAAGACA GACTCCAAAT 
GACCGCCAGC ATGCCATCCA GTTCCTCTTG GTCTTCCTGC TTGGGAACGA GGAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011249310.1
CDS	236..2935
Translation	MEPRLPIGAQPLAMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKDSSSWYQKLDTMDKPAYSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSYLEKEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED

Target ORF information:

RefSeq Version	XM_011251008.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011251008.3

ORF Insert Sequence:

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGC AGAAGAAACT CTTTTGATTG ATATTGCTTC AAACAGTGGC 
TGCAAAATTC GGGTACAGGG AGACTGGACC AGAGAGCGCC ACTTTGAAAT TCCTGATGAA 
GAACGCTGTT TGAAGTTCCT CTCAGAGGTC CTCGAAGCTC AGGAAGCTCA GTCACAGCTT 
CTTGTTCCAG AACAAAAAGA CTCATCTAGC TGGTACCAGA AATTAGACAC TATGGATAAA 
CCTGCTTATT CAGGGCTGCT TGGATTTGAG GATAATTTTT CATCTCTGGA TTTAGATAAG 
AAAATGAATA CACAAAATCC CCGATCAGGG AGTCATCGGG AACCACCCCC TCCACCTTCT 
TCATCGACTA GAATGCTTTC GCGTGAAAAG GAAGCTTCAA ACAAAGAACA GCCCAAAGTG 
ACCAATACCA TGCGGAAGCT ATTTGTCCCG AACACCCAAA CCGGGCAGCG AGAGGGTCTC 
ATTAAACATA TCCTCACAAA GCGAGAGAAA GAATATGTCA ACATCCAGTC TTTCAGGTTT 
TTTGTTGGAA CTTGGAATGT GAACGGCCAG TCTCCAGACA GCAGCTTAGA ACCTTGGCTC 
GACTGTGATC CAAATCCTCC TGATATTTAC TGCATTGGAT TCCAAGAGCT GGACTTGAGC 
ACCGAAGCCT TTTTCTACTT CGAGTCTGTG AAAGAGCAAG AGTGGTCCTT GGCTGTGGAA 
AGGGGGCTGC CTTCGAAGGC CAAGTATAGA AAAGTTCAAC TGGTCCGCCT TGTGGGGATG 
ATGCTTCTTA TATTTGCCAG AAAAGATCAG TGTCAATACA TCCGAGATGT TGCTACAGAA 
ACAACTGGAA CTGGAATCAT GGGGAAAATG GGAAACAAAG GTGGGGTAGC TGTAAGATTT 
GTATTCCACA ACACCACTTT CTGCATTGTC AATTCGCACC TGGCCGCCCA CGTGGAAGAG 
TTCGAACGAA GGAATCAGGA TTATAAAGAC ATCTGTGCAA GAATGACTTT TTCAGTCCCC 
AATCAGACTG TCCCGCAAGT GAACATCATG AAGCATGATG TTGTCATTTG GCTGGGAGAC 
TTGAACTACA GACTTTGCAT GCCTGATGCC AGTGAGGTGA AAAGTCTTAT TAATAAAAAT 
GAGCTTCATA AGCTGTTGAA ATTTGACCAG TTAAACATTC AGCGCACACA GAAAAAAGCT 
TTTGCGGATT TCAATGAAGG GGAAATTAAT TTCGTTCCCA CGTACAAATA TGATTCGAAA 
ACTGACAGAT GGGATTCCAG TGGGAAATGC CGAGTTCCCG CCTGGTGTGA CCGAATTCTT 
TGGAGAGGAA TAAATGTTAA TCAACTTCAT TACCGGAGTC ACATGGAACT CAAAACTAGT 
GACCACAAAC CTGTTAGCGC CCTGTTCCAT ATTGGGGTGA AGGTTGTGGA TGAGCGGAGG 
TATCGGAAGG TCTTTGAAGA TATCGTCCGC ATTATGGACA GAATGGAAAA CGACTTCCTT 
CCTTCATTAG AACTTAGCAG GAGAGAGTTT TTTTTTGAGA ATGTGAAGTT TCGGCAGCTG 
CAAAAGGAGA AGTTCCAGAT CAGCAACAAT GGACAGGTTC CCTGCCATTT TTCTTTCATC 
CCTAAGCTTA ATGACAGCCA ATACTGCAAG CCATGGCTTC GAGCTGAACC TTTTGAGGGC 
TACTTGGAGC CAAACGAGAC CTTAGACATC TCCCTTGATG TATACGTCAG CAAAGACTCT 
GTAACCATCC TGAACTCCGG TGAAGATAAG ATTGAAGATA TTCTTGTCCT CCATTTGGAT 
CGAGGCAAAG ATTACTTCTT GACCATCGGT GGGAATTACC TCCCAAGTTG CTTTGGAACC 
TCATTGGAGG CTTTGTGCCG AATGAAAAGA CCAATTCGAG AAGTTCCTGT CACCAAACTC 
ATAGACCTGG AAGAAGACAG CTACCTAGAA AAGGAGAAAT CCCTTCTGCA GATGGTACCC 
TTGGATGAAG GTACCAGTGA GCGACCCCTT CAAGTCCCCA AAGAGATCTG GCTTCTAGTA 
GATCACTTGT TCAAATATGC ATGTCACCAG GAGGACTTGT TCCAAACCCC TGGAATGCAG 
GAGGAGTTAC AGCAGATCAT TGATTGCCTG GATACCAGCA TTCCTGAGAC AATTCCTGGC 
AATAACCATT CTGTGGCTGA AGCACTGCTC ATTTTCCTGG AAGCTCTGCC AGAGCCAGTC 
ATCTGTTATG AGCTGTATCA GCGATGTCTT GACTCTGCTC ATGATCCTCG GATCTGCAAA 
CAGGTCATTT CCCAGCTTCC AAGGTGCCAT AGAAATGTTT TCCGCTACTT GATGGCATTC 
CTTCGTGAAC TCTTAAAATT CTCTGACTAC AACAATATCA ACACCAACAT GATTGCTACC 
CTGTTCAGTA GCCTTCTCCT AAGACCTCCA CCAAACCTCA TGACAAGACA GACTCCAAAT 
GACCGCCAGC ATGCCATCCA GTTCCTCTTG GTCTTCCTGC TTGGGAACGA GGAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ocrl ( XM_017318524.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017174013.1 Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu83139
Clone ID Related Accession (Same CDS sequence)	XM_017318524.2 , XM_017318524.1
Accession Version	XM_017318524.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2679bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate 5-phosphatase OCRL-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017318524.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGA AGCAGAAGAA ACTCTTTTGA TTGATATTGC TTCAAACAGT 
GGCTGCAAAA TTCGGGTACA GGGAGACTGG ACCAGAGAGC GCCACTTTGA AATTCCTGAT 
GAAGAACGCT GTTTGAAGTT CCTCTCAGAG GTCCTCGAAG CTCAGGAAGC TCAGTCACAG 
CTTCTTGTTC CAGAACAAAA AGACTCATCT AGCTGGTACC AGAAATTAGA CACTATGGAT 
AAACCTGCTT ATTCAGGGCT GCTTGGATTT GAGGATAATT TTTCATCTCT GGATTTAGAT 
AAGAAAATGA ATACACAAAA TCCCCGATCA GGGAGTCATC GGGAACCACC CCCTCCACCT 
TCTTCATCGA CTAGAATGCT TTCGCGTGAA AAGGAAGCTT CAAACAAAGA ACAGCCCAAA 
GTGACCAATA CCATGCGGAA GCTATTTGTC CCGAACACCC AAACCGGGCA GCGAGAGGGT 
CTCATTAAAC ATATCCTCAC AAAGCGAGAG AAAGAATATG TCAACATCCA GTCTTTCAGG 
TTTTTTGTTG GAACTTGGAA TGTGAACGGC CAGTCTCCAG ACAGCAGCTT AGAACCTTGG 
CTCGACTGTG ATCCAAATCC TCCTGATATT TACTGCATTG GATTCCAAGA GCTGGACTTG 
AGCACCGAAG CCTTTTTCTA CTTCGAGTCT GTGAAAGAGC AAGAGTGGTC CTTGGCTGTG 
GAAAGGGGGC TGCCTTCGAA GGCCAAGTAT AGAAAAGTTC AACTGGTCCG CCTTGTGGGG 
ATGATGCTTC TTATATTTGC CAGAAAAGAT CAGTGTCAAT ACATCCGAGA TGTTGCTACA 
GAAACAACTG GAACTGGAAT CATGGGGAAA ATGGGAAACA AAGGTGGGGT AGCTGTAAGA 
TTTGTATTCC ACAACACCAC TTTCTGCATT GTCAATTCGC ACCTGGCCGC CCACGTGGAA 
GAGTTCGAAC GAAGGAATCA GGATTATAAA GACATCTGTG CAAGAATGAC TTTTTCAGTC 
CCCAATCAGA CTGTCCCGCA AGTGAACATC ATGAAGCATG ATGTTGTCAT TTGGCTGGGA 
GACTTGAACT ACAGACTTTG CATGCCTGAT GCCAGTGAGG TGAAAAGTCT TATTAATAAA 
AATGAGCTTC ATAAGCTGTT GAAATTTGAC CAGTTAAACA TTCAGCGCAC ACAGAAAAAA 
GCTTTTGCGG ATTTCAATGA AGGGGAAATT AATTTCGTTC CCACGTACAA ATATGATTCG 
AAAACTGACA GATGGGATTC CAGTGGGAAA TGCCGAGTTC CCGCCTGGTG TGACCGAATT 
CTTTGGAGAG GAATAAATGT TAATCAACTT CATTACCGGA GTCACATGGA ACTCAAAACT 
AGTGACCACA AACCTGTTAG CGCCCTGTTC CATATTGGGG TGAAGGTTGT GGATGAGCGG 
AGGTATCGGA AGGTCTTTGA AGATATCGTC CGCATTATGG ACAGAATGGA AAACGACTTC 
CTTCCTTCAT TAGAACTTAG CAGGAGAGAG TTTTTTTTTG AGAATGTGAA GTTTCGGCAG 
CTGCAAAAGG AGAAGTTCCA GATCAGCAAC AATGGACAGG TTCCCTGCCA TTTTTCTTTC 
ATCCCTAAGC TTAATGACAG CCAATACTGC AAGCCATGGC TTCGAGCTGA ACCTTTTGAG 
GGCTACTTGG AGCCAAACGA GACCTTAGAC ATCTCCCTTG ATGTATACGT CAGCAAAGAC 
TCTGTAACCA TCCTGAACTC CGGTGAAGAT AAGATTGAAG ATATTCTTGT CCTCCATTTG 
GATCGAGGCA AAGATTACTT CTTGACCATC GGTGGGAATT ACCTCCCAAG TTGCTTTGGA 
ACCTCATTGG AGGCTTTGTG CCGAATGAAA AGACCAATTC GAGAAGTTCC TGTCACCAAA 
CTCATAGACC TGGAGAAATC CCTTCTGCAG ATGGTACCCT TGGATGAAGG TACCAGTGAG 
CGACCCCTTC AAGTCCCCAA AGAGATCTGG CTTCTAGTAG ATCACTTGTT CAAATATGCA 
TGTCACCAGG AGGACTTGTT CCAAACCCCT GGAATGCAGG AGGAGTTACA GCAGATCATT 
GATTGCCTGG ATACCAGCAT TCCTGAGACA ATTCCTGGCA ATAACCATTC TGTGGCTGAA 
GCACTGCTCA TTTTCCTGGA AGCTCTGCCA GAGCCAGTCA TCTGTTATGA GCTGTATCAG 
CGATGTCTTG ACTCTGCTCA TGATCCTCGG ATCTGCAAAC AGGTCATTTC CCAGCTTCCA 
AGGTGCCATA GAAATGTTTT CCGCTACTTG ATGGCATTCC TTCGTGAACT CTTAAAATTC 
TCTGACTACA ACAATATCAA CACCAACATG ATTGCTACCC TGTTCAGTAG CCTTCTCCTA 
AGACCTCCAC CAAACCTCAT GACAAGACAG ACTCCAAATG ACCGCCAGCA TGCCATCCAG 
TTCCTCTTGG TCTTCCTGCT TGGGAACGAG GAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017174013.1
CDS	236..2914
Translation	MEPRLPIGAQPLAMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKDSSSWYQKLDTMDKPAYSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED

Target ORF information:

RefSeq Version	XM_017318524.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus OCRL, inositol polyphosphate-5-phosphatase (Ocrl), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318524.2

ORF Insert Sequence:

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGA AGCAGAAGAA ACTCTTTTGA TTGATATTGC TTCAAACAGT 
GGCTGCAAAA TTCGGGTACA GGGAGACTGG ACCAGAGAGC GCCACTTTGA AATTCCTGAT 
GAAGAACGCT GTTTGAAGTT CCTCTCAGAG GTCCTCGAAG CTCAGGAAGC TCAGTCACAG 
CTTCTTGTTC CAGAACAAAA AGACTCATCT AGCTGGTACC AGAAATTAGA CACTATGGAT 
AAACCTGCTT ATTCAGGGCT GCTTGGATTT GAGGATAATT TTTCATCTCT GGATTTAGAT 
AAGAAAATGA ATACACAAAA TCCCCGATCA GGGAGTCATC GGGAACCACC CCCTCCACCT 
TCTTCATCGA CTAGAATGCT TTCGCGTGAA AAGGAAGCTT CAAACAAAGA ACAGCCCAAA 
GTGACCAATA CCATGCGGAA GCTATTTGTC CCGAACACCC AAACCGGGCA GCGAGAGGGT 
CTCATTAAAC ATATCCTCAC AAAGCGAGAG AAAGAATATG TCAACATCCA GTCTTTCAGG 
TTTTTTGTTG GAACTTGGAA TGTGAACGGC CAGTCTCCAG ACAGCAGCTT AGAACCTTGG 
CTCGACTGTG ATCCAAATCC TCCTGATATT TACTGCATTG GATTCCAAGA GCTGGACTTG 
AGCACCGAAG CCTTTTTCTA CTTCGAGTCT GTGAAAGAGC AAGAGTGGTC CTTGGCTGTG 
GAAAGGGGGC TGCCTTCGAA GGCCAAGTAT AGAAAAGTTC AACTGGTCCG CCTTGTGGGG 
ATGATGCTTC TTATATTTGC CAGAAAAGAT CAGTGTCAAT ACATCCGAGA TGTTGCTACA 
GAAACAACTG GAACTGGAAT CATGGGGAAA ATGGGAAACA AAGGTGGGGT AGCTGTAAGA 
TTTGTATTCC ACAACACCAC TTTCTGCATT GTCAATTCGC ACCTGGCCGC CCACGTGGAA 
GAGTTCGAAC GAAGGAATCA GGATTATAAA GACATCTGTG CAAGAATGAC TTTTTCAGTC 
CCCAATCAGA CTGTCCCGCA AGTGAACATC ATGAAGCATG ATGTTGTCAT TTGGCTGGGA 
GACTTGAACT ACAGACTTTG CATGCCTGAT GCCAGTGAGG TGAAAAGTCT TATTAATAAA 
AATGAGCTTC ATAAGCTGTT GAAATTTGAC CAGTTAAACA TTCAGCGCAC ACAGAAAAAA 
GCTTTTGCGG ATTTCAATGA AGGGGAAATT AATTTCGTTC CCACGTACAA ATATGATTCG 
AAAACTGACA GATGGGATTC CAGTGGGAAA TGCCGAGTTC CCGCCTGGTG TGACCGAATT 
CTTTGGAGAG GAATAAATGT TAATCAACTT CATTACCGGA GTCACATGGA ACTCAAAACT 
AGTGACCACA AACCTGTTAG CGCCCTGTTC CATATTGGGG TGAAGGTTGT GGATGAGCGG 
AGGTATCGGA AGGTCTTTGA AGATATCGTC CGCATTATGG ACAGAATGGA AAACGACTTC 
CTTCCTTCAT TAGAACTTAG CAGGAGAGAG TTTTTTTTTG AGAATGTGAA GTTTCGGCAG 
CTGCAAAAGG AGAAGTTCCA GATCAGCAAC AATGGACAGG TTCCCTGCCA TTTTTCTTTC 
ATCCCTAAGC TTAATGACAG CCAATACTGC AAGCCATGGC TTCGAGCTGA ACCTTTTGAG 
GGCTACTTGG AGCCAAACGA GACCTTAGAC ATCTCCCTTG ATGTATACGT CAGCAAAGAC 
TCTGTAACCA TCCTGAACTC CGGTGAAGAT AAGATTGAAG ATATTCTTGT CCTCCATTTG 
GATCGAGGCA AAGATTACTT CTTGACCATC GGTGGGAATT ACCTCCCAAG TTGCTTTGGA 
ACCTCATTGG AGGCTTTGTG CCGAATGAAA AGACCAATTC GAGAAGTTCC TGTCACCAAA 
CTCATAGACC TGGAGAAATC CCTTCTGCAG ATGGTACCCT TGGATGAAGG TACCAGTGAG 
CGACCCCTTC AAGTCCCCAA AGAGATCTGG CTTCTAGTAG ATCACTTGTT CAAATATGCA 
TGTCACCAGG AGGACTTGTT CCAAACCCCT GGAATGCAGG AGGAGTTACA GCAGATCATT 
GATTGCCTGG ATACCAGCAT TCCTGAGACA ATTCCTGGCA ATAACCATTC TGTGGCTGAA 
GCACTGCTCA TTTTCCTGGA AGCTCTGCCA GAGCCAGTCA TCTGTTATGA GCTGTATCAG 
CGATGTCTTG ACTCTGCTCA TGATCCTCGG ATCTGCAAAC AGGTCATTTC CCAGCTTCCA 
AGGTGCCATA GAAATGTTTT CCGCTACTTG ATGGCATTCC TTCGTGAACT CTTAAAATTC 
TCTGACTACA ACAATATCAA CACCAACATG ATTGCTACCC TGTTCAGTAG CCTTCTCCTA 
AGACCTCCAC CAAACCTCAT GACAAGACAG ACTCCAAATG ACCGCCAGCA TGCCATCCAG 
TTCCTCTTGG TCTTCCTGCT TGGGAACGAG GAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ocrl ( XM_017318524.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017174013.1 Mus musculus oculocerebrorenal syndrome of Lowe (Ocrl), transcript variant X2, mRNA.

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CloneID	OMu83139
Clone ID Related Accession (Same CDS sequence)	XM_017318524.2 , XM_017318524.1
Accession Version	XM_017318524.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2679bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate 5-phosphatase OCRL-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGA AGCAGAAGAA ACTCTTTTGA TTGATATTGC TTCAAACAGT 
GGCTGCAAAA TTCGGGTACA GGGAGACTGG ACCAGAGAGC GCCACTTTGA AATTCCTGAT 
GAAGAACGCT GTTTGAAGTT CCTCTCAGAG GTCCTCGAAG CTCAGGAAGC TCAGTCACAG 
CTTCTTGTTC CAGAACAAAA AGACTCATCT AGCTGGTACC AGAAATTAGA CACTATGGAT 
AAACCTGCTT ATTCAGGGCT GCTTGGATTT GAGGATAATT TTTCATCTCT GGATTTAGAT 
AAGAAAATGA ATACACAAAA TCCCCGATCA GGGAGTCATC GGGAACCACC CCCTCCACCT 
TCTTCATCGA CTAGAATGCT TTCGCGTGAA AAGGAAGCTT CAAACAAAGA ACAGCCCAAA 
GTGACCAATA CCATGCGGAA GCTATTTGTC CCGAACACCC AAACCGGGCA GCGAGAGGGT 
CTCATTAAAC ATATCCTCAC AAAGCGAGAG AAAGAATATG TCAACATCCA GTCTTTCAGG 
TTTTTTGTTG GAACTTGGAA TGTGAACGGC CAGTCTCCAG ACAGCAGCTT AGAACCTTGG 
CTCGACTGTG ATCCAAATCC TCCTGATATT TACTGCATTG GATTCCAAGA GCTGGACTTG 
AGCACCGAAG CCTTTTTCTA CTTCGAGTCT GTGAAAGAGC AAGAGTGGTC CTTGGCTGTG 
GAAAGGGGGC TGCCTTCGAA GGCCAAGTAT AGAAAAGTTC AACTGGTCCG CCTTGTGGGG 
ATGATGCTTC TTATATTTGC CAGAAAAGAT CAGTGTCAAT ACATCCGAGA TGTTGCTACA 
GAAACAACTG GAACTGGAAT CATGGGGAAA ATGGGAAACA AAGGTGGGGT AGCTGTAAGA 
TTTGTATTCC ACAACACCAC TTTCTGCATT GTCAATTCGC ACCTGGCCGC CCACGTGGAA 
GAGTTCGAAC GAAGGAATCA GGATTATAAA GACATCTGTG CAAGAATGAC TTTTTCAGTC 
CCCAATCAGA CTGTCCCGCA AGTGAACATC ATGAAGCATG ATGTTGTCAT TTGGCTGGGA 
GACTTGAACT ACAGACTTTG CATGCCTGAT GCCAGTGAGG TGAAAAGTCT TATTAATAAA 
AATGAGCTTC ATAAGCTGTT GAAATTTGAC CAGTTAAACA TTCAGCGCAC ACAGAAAAAA 
GCTTTTGCGG ATTTCAATGA AGGGGAAATT AATTTCGTTC CCACGTACAA ATATGATTCG 
AAAACTGACA GATGGGATTC CAGTGGGAAA TGCCGAGTTC CCGCCTGGTG TGACCGAATT 
CTTTGGAGAG GAATAAATGT TAATCAACTT CATTACCGGA GTCACATGGA ACTCAAAACT 
AGTGACCACA AACCTGTTAG CGCCCTGTTC CATATTGGGG TGAAGGTTGT GGATGAGCGG 
AGGTATCGGA AGGTCTTTGA AGATATCGTC CGCATTATGG ACAGAATGGA AAACGACTTC 
CTTCCTTCAT TAGAACTTAG CAGGAGAGAG TTTTTTTTTG AGAATGTGAA GTTTCGGCAG 
CTGCAAAAGG AGAAGTTCCA GATCAGCAAC AATGGACAGG TTCCCTGCCA TTTTTCTTTC 
ATCCCTAAGC TTAATGACAG CCAATACTGC AAGCCATGGC TTCGAGCTGA ACCTTTTGAG 
GGCTACTTGG AGCCAAACGA GACCTTAGAC ATCTCCCTTG ATGTATACGT CAGCAAAGAC 
TCTGTAACCA TCCTGAACTC CGGTGAAGAT AAGATTGAAG ATATTCTTGT CCTCCATTTG 
GATCGAGGCA AAGATTACTT CTTGACCATC GGTGGGAATT ACCTCCCAAG TTGCTTTGGA 
ACCTCATTGG AGGCTTTGTG CCGAATGAAA AGACCAATTC GAGAAGTTCC TGTCACCAAA 
CTCATAGACC TGGAGAAATC CCTTCTGCAG ATGGTACCCT TGGATGAAGG TACCAGTGAG 
CGACCCCTTC AAGTCCCCAA AGAGATCTGG CTTCTAGTAG ATCACTTGTT CAAATATGCA 
TGTCACCAGG AGGACTTGTT CCAAACCCCT GGAATGCAGG AGGAGTTACA GCAGATCATT 
GATTGCCTGG ATACCAGCAT TCCTGAGACA ATTCCTGGCA ATAACCATTC TGTGGCTGAA 
GCACTGCTCA TTTTCCTGGA AGCTCTGCCA GAGCCAGTCA TCTGTTATGA GCTGTATCAG 
CGATGTCTTG ACTCTGCTCA TGATCCTCGG ATCTGCAAAC AGGTCATTTC CCAGCTTCCA 
AGGTGCCATA GAAATGTTTT CCGCTACTTG ATGGCATTCC TTCGTGAACT CTTAAAATTC 
TCTGACTACA ACAATATCAA CACCAACATG ATTGCTACCC TGTTCAGTAG CCTTCTCCTA 
AGACCTCCAC CAAACCTCAT GACAAGACAG ACTCCAAATG ACCGCCAGCA TGCCATCCAG 
TTCCTCTTGG TCTTCCTGCT TGGGAACGAG GAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017174013.1
CDS	253..2931
Translation	MEPRLPIGAQPLAMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKDSSSWYQKLDTMDKPAYSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED

Target ORF information:

RefSeq Version	XM_017318524.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus oculocerebrorenal syndrome of Lowe (Ocrl), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318524.1

ORF Insert Sequence:

ATGGAGCCGC GGCTCCCGAT TGGAGCTCAG CCCCTGGCAA TGGTGGCGGG TTTGGAGATG 
AAGGGTCCCC TCCGGGAACC CTGCGTCCTG ACCCTAGCCC GGAGGAATGG GCAGTATGAG 
TTAATAATCC AGTTGCATGG AAAGGAACAA CATGTTCAAG ATATCATTCC TATAAATAGC 
CACTTCAGAT GTGTTCAAGA AGCAGAAGAA ACTCTTTTGA TTGATATTGC TTCAAACAGT 
GGCTGCAAAA TTCGGGTACA GGGAGACTGG ACCAGAGAGC GCCACTTTGA AATTCCTGAT 
GAAGAACGCT GTTTGAAGTT CCTCTCAGAG GTCCTCGAAG CTCAGGAAGC TCAGTCACAG 
CTTCTTGTTC CAGAACAAAA AGACTCATCT AGCTGGTACC AGAAATTAGA CACTATGGAT 
AAACCTGCTT ATTCAGGGCT GCTTGGATTT GAGGATAATT TTTCATCTCT GGATTTAGAT 
AAGAAAATGA ATACACAAAA TCCCCGATCA GGGAGTCATC GGGAACCACC CCCTCCACCT 
TCTTCATCGA CTAGAATGCT TTCGCGTGAA AAGGAAGCTT CAAACAAAGA ACAGCCCAAA 
GTGACCAATA CCATGCGGAA GCTATTTGTC CCGAACACCC AAACCGGGCA GCGAGAGGGT 
CTCATTAAAC ATATCCTCAC AAAGCGAGAG AAAGAATATG TCAACATCCA GTCTTTCAGG 
TTTTTTGTTG GAACTTGGAA TGTGAACGGC CAGTCTCCAG ACAGCAGCTT AGAACCTTGG 
CTCGACTGTG ATCCAAATCC TCCTGATATT TACTGCATTG GATTCCAAGA GCTGGACTTG 
AGCACCGAAG CCTTTTTCTA CTTCGAGTCT GTGAAAGAGC AAGAGTGGTC CTTGGCTGTG 
GAAAGGGGGC TGCCTTCGAA GGCCAAGTAT AGAAAAGTTC AACTGGTCCG CCTTGTGGGG 
ATGATGCTTC TTATATTTGC CAGAAAAGAT CAGTGTCAAT ACATCCGAGA TGTTGCTACA 
GAAACAACTG GAACTGGAAT CATGGGGAAA ATGGGAAACA AAGGTGGGGT AGCTGTAAGA 
TTTGTATTCC ACAACACCAC TTTCTGCATT GTCAATTCGC ACCTGGCCGC CCACGTGGAA 
GAGTTCGAAC GAAGGAATCA GGATTATAAA GACATCTGTG CAAGAATGAC TTTTTCAGTC 
CCCAATCAGA CTGTCCCGCA AGTGAACATC ATGAAGCATG ATGTTGTCAT TTGGCTGGGA 
GACTTGAACT ACAGACTTTG CATGCCTGAT GCCAGTGAGG TGAAAAGTCT TATTAATAAA 
AATGAGCTTC ATAAGCTGTT GAAATTTGAC CAGTTAAACA TTCAGCGCAC ACAGAAAAAA 
GCTTTTGCGG ATTTCAATGA AGGGGAAATT AATTTCGTTC CCACGTACAA ATATGATTCG 
AAAACTGACA GATGGGATTC CAGTGGGAAA TGCCGAGTTC CCGCCTGGTG TGACCGAATT 
CTTTGGAGAG GAATAAATGT TAATCAACTT CATTACCGGA GTCACATGGA ACTCAAAACT 
AGTGACCACA AACCTGTTAG CGCCCTGTTC CATATTGGGG TGAAGGTTGT GGATGAGCGG 
AGGTATCGGA AGGTCTTTGA AGATATCGTC CGCATTATGG ACAGAATGGA AAACGACTTC 
CTTCCTTCAT TAGAACTTAG CAGGAGAGAG TTTTTTTTTG AGAATGTGAA GTTTCGGCAG 
CTGCAAAAGG AGAAGTTCCA GATCAGCAAC AATGGACAGG TTCCCTGCCA TTTTTCTTTC 
ATCCCTAAGC TTAATGACAG CCAATACTGC AAGCCATGGC TTCGAGCTGA ACCTTTTGAG 
GGCTACTTGG AGCCAAACGA GACCTTAGAC ATCTCCCTTG ATGTATACGT CAGCAAAGAC 
TCTGTAACCA TCCTGAACTC CGGTGAAGAT AAGATTGAAG ATATTCTTGT CCTCCATTTG 
GATCGAGGCA AAGATTACTT CTTGACCATC GGTGGGAATT ACCTCCCAAG TTGCTTTGGA 
ACCTCATTGG AGGCTTTGTG CCGAATGAAA AGACCAATTC GAGAAGTTCC TGTCACCAAA 
CTCATAGACC TGGAGAAATC CCTTCTGCAG ATGGTACCCT TGGATGAAGG TACCAGTGAG 
CGACCCCTTC AAGTCCCCAA AGAGATCTGG CTTCTAGTAG ATCACTTGTT CAAATATGCA 
TGTCACCAGG AGGACTTGTT CCAAACCCCT GGAATGCAGG AGGAGTTACA GCAGATCATT 
GATTGCCTGG ATACCAGCAT TCCTGAGACA ATTCCTGGCA ATAACCATTC TGTGGCTGAA 
GCACTGCTCA TTTTCCTGGA AGCTCTGCCA GAGCCAGTCA TCTGTTATGA GCTGTATCAG 
CGATGTCTTG ACTCTGCTCA TGATCCTCGG ATCTGCAAAC AGGTCATTTC CCAGCTTCCA 
AGGTGCCATA GAAATGTTTT CCGCTACTTG ATGGCATTCC TTCGTGAACT CTTAAAATTC 
TCTGACTACA ACAATATCAA CACCAACATG ATTGCTACCC TGTTCAGTAG CCTTCTCCTA 
AGACCTCCAC CAAACCTCAT GACAAGACAG ACTCCAAATG ACCGCCAGCA TGCCATCCAG 
TTCCTCTTGG TCTTCCTGCT TGGGAACGAG GAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.
Developmental cell43(3)318-331.e5(2017 11)
Rohacek AM,Bebee TW,Tilton RK,Radens CM,McDermott-Roe C,Peart N,Kaur M,Zaykaner M,Cieply B,Musunuru K,Barash Y,Germiller JA,Krantz ID,Carstens RP,Epstein DJ

Kidney Tubular Ablation of
Journal of the American Society of Nephrology : JASN28(5)1399-1407(2017 May)
Inoue K,Balkin DM,Liu L,Nandez R,Wu Y,Tian X,Wang T,Nussbaum R,De Camilli P,Ishibe S

Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development.
Arthritis & rheumatology (Hoboken, N.J.)67(8)2154-63(2015 May)
Zhu S,Dai J,Liu H,Cong X,Chen Y,Wu Y,Hu H,Heng BC,Ouyang HW,Zhou Y

Primary cilia signaling mediates intraocular pressure sensation.
Proceedings of the National Academy of Sciences of the United States of America111(35)12871-6(2014 Sep)
Luo N,Conwell MD,Chen X,Kettenhofen CI,Westlake CJ,Cantor LB,Wells CD,Weinreb RN,Corson TW,Spandau DF,Joos KM,Iomini C,Obukhov AG,Sun Y

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Ocrl cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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