Gene Symbol | Pold4 |
Entrez Gene ID | 69745 |
Full Name | polymerase (DNA-directed), delta 4 |
Synonyms | 2410012M21Rik,AI463381,AW060307,Polds,p12 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Pold4 cDNA ORF clone
gRNAs
Gene Symbol | Pold4 |
Entrez Gene ID | 69745 |
Full Name | polymerase (DNA-directed), delta 4 |
Synonyms | 2410012M21Rik,AI463381,AW060307,Polds,p12 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_027196.4 | NP_081472.1 | DNA polymerase delta subunit 4 |
Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase ? for degradation in response to DNA damage.
Zhang S, Zhou Y, Sarkeshik A, Yates JR 3rd, Thomson TM, Zhang Z, Lee EY, Lee MY
The Journal of biological chemistry288(5)2941-50(2013 Feb)
FGF2-induced upregulation of DNA polymerase-delta p12 subunit in endothelial cells.
Dell'Era P, Nicoli S, Peri G, Nieddu M, Ennas MG, Presta M
Oncogene24(6)1117-21(2005 Feb)
Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.
VanBuren V, Piao Y, Dudekula DB, Qian Y, Carter MG, Martin PR, Stagg CA, Bassey UC, Aiba K, Hamatani T, Kargul GJ, Luo AG, Kelso J, Hide W, Ko MS
Genome research12(12)1999-2003(2002 Dec)
Gene expression profile in fibroblast growth factor 2-transformed endothelial cells.
Dell'Era P, Coco L, Ronca R, Sennino B, Presta M
Oncogene21(15)2433-40(2002 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The identification of RNF8 allows new insights into the integration of the control of p12 degradation by different DNA damage signaling pathways.
Title: Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase ? for degradation in response to DNA damage.
The following Pold4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pold4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu13535 | |
Clone ID Related Accession (Same CDS sequence) | NM_027196.4 | |
Accession Version | NM_027196.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 324bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-01-11 | |
Organism | Mus musculus(house mouse) | |
Product | DNA polymerase delta subunit 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC109138.10 and BC028520.1. On Jun 20, 2015 this sequence version replaced NM_027196.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. ##Evidence-Data-START## Transcript exon combination :: BY709901.1, CB194474.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGTCGGA AGCGGTTCAT CACTGACTCC TATCCTGTTG TGAAGAAGAG GGAGGGGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_081472.1 |
CDS | 200..523 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGGTCGGA AGCGGTTCAT CACTGACTCC TATCCTGTTG TGAAGAAGAG GGAGGGGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase ? for degradation in response to DNA damage. |
FGF2-induced upregulation of DNA polymerase-delta p12 subunit in endothelial cells. |
Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. |
Gene expression profile in fibroblast growth factor 2-transformed endothelial cells. |