Gene Symbol | Eif3k |
Entrez Gene ID | 73830 |
Full Name | eukaryotic translation initiation factor 3, subunit K |
Synonyms | 1200009C21Rik,Eif3s12 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Eif3k cDNA ORF clone
gRNAs
Gene Symbol | Eif3k |
Entrez Gene ID | 73830 |
Full Name | eukaryotic translation initiation factor 3, subunit K |
Synonyms | 1200009C21Rik,Eif3s12 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001285943.1 | NP_001272872.1 | eukaryotic translation initiation factor 3 subunit K isoform 3 |
NM_028659.3 | NP_082935.1 | eukaryotic translation initiation factor 3 subunit K isoform 1 |
XM_006540392.3 | XP_006540455.1 | eukaryotic translation initiation factor 3 subunit K isoform X1 |
NM_001285942.1 | NP_001272871.1 | eukaryotic translation initiation factor 3 subunit K isoform 2 |
XM_006540392.4 | XP_006540455.1 | eukaryotic translation initiation factor 3 subunit K isoform X1 |
Rattus norvegicus (Norway rat) | Eif3k | NP_001099712.1 |
Arabidopsis thaliana (thale cress) | EIF3K | NP_195051.1 |
Xenopus tropicalis (tropical clawed frog) | eif3k | NP_001165760.1 |
Homo sapiens (human) | EIF3K | NP_037366.1 |
Danio rerio (zebrafish) | eif3k | NP_001017583.1 |
Drosophila melanogaster (fruit fly) | CG10306 | NP_611604.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03855 | XP_003720036.1 |
Oryza sativa (rice) | Os03g0182700 | NP_001049175.2 |
Anopheles gambiae (African malaria mosquito) | EIF3K_ANOGA | XP_309930.2 |
Caenorhabditis elegans (roundworm) | eif-3.K | NP_506241.1 |
Bos taurus (cattle) | EIF3K | NP_001029661.1 |
Mus musculus (house mouse) | Eif3k | NP_082935.1 |
Gallus gallus (chicken) | LOC101750374 | XP_004950279.1 |
Neurospora crassa | NCU09707 | XP_958946.1 |
Pan troglodytes (chimpanzee) | EIF3K | XP_512639.2 |
EIF3K | XP_001082764.1 | |
Canis lupus familiaris (dog) | EIF3K | XP_533679.1 |
eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions.
Lin YM, Chen YR, Lin JR, Wang WJ, Inoko A, Inagaki M, Wu YC, Chen RH
Journal of cell science121(Pt 14)2382-93(2008 Jul)
Reconstitution reveals the functional core of mammalian eIF3.
Masutani M, Sonenberg N, Yokoyama S, Imataka H
The EMBO journal26(14)3373-83(2007 Jul)
Crystal structure of human eIF3k, the first structure of eIF3 subunits.
Wei Z, Zhang P, Zhou Z, Cheng Z, Wan M, Gong W
The Journal of biological chemistry279(33)34983-90(2004 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Eif3k gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif3k cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu38519 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540392.3 , XM_006540392.4 | |
Accession Version | XM_006540392.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic translation initiation factor 3 subunit K isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540392.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATCGACC AGGCACATCA AGAAGAGCGG CCCATCCGGC AGATCTTGTA CCTCGGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540455.1 |
CDS | 543..938 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATCGACC AGGCACATCA AGAAGAGCGG CCCATCCGGC AGATCTTGTA CCTCGGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05924 | |
Clone ID Related Accession (Same CDS sequence) | NM_028659.3 | |
Accession Version | NM_028659.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic translation initiation factor 3 subunit K isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166357.3, AK004664.1 and CD802664.1. On Oct 25, 2013 this sequence version replaced NM_028659.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC091749.1, CA468633.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGATGT TTGAGCAGAT GAGAGCGAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_082935.1 |
CDS | 157..813 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGATGT TTGAGCAGAT GAGAGCGAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09034 | |
Clone ID Related Accession (Same CDS sequence) | NM_001285943.1 | |
Accession Version | NM_001285943.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic translation initiation factor 3 subunit K isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166357.3 and AK158875.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) lacks an alternate internal segment and has a longer and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK158875.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGATGT TTGAGCAGAT GAGAGCGAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001272872.1 |
CDS | 157..735 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGATGT TTGAGCAGAT GAGAGCGAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09031 | |
Clone ID Related Accession (Same CDS sequence) | NM_001285942.1 | |
Accession Version | NM_001285942.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic translation initiation factor 3 subunit K isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC166357.3, BC027638.1 and CD802664.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC027638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGATGT TTGAGCAGAT GAGAGCGAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001272871.1 |
CDS | 157..714 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGATGT TTGAGCAGAT GAGAGCGAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu38519 | |
Clone ID Related Accession (Same CDS sequence) | XM_006540392.3 , XM_006540392.4 | |
Accession Version | XM_006540392.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | eukaryotic translation initiation factor 3 subunit K isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006540392.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATCGACC AGGCACATCA AGAAGAGCGG CCCATCCGGC AGATCTTGTA CCTCGGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006540455.1 |
CDS | 545..940 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGATCGACC AGGCACATCA AGAAGAGCGG CCCATCCGGC AGATCTTGTA CCTCGGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions. |
Reconstitution reveals the functional core of mammalian eIF3. |
Crystal structure of human eIF3k, the first structure of eIF3 subunits. |