Gas2l1 cDNA ORF clone, Mus musculus(house mouse)
Gene Symbol | Gas2l1 |
Entrez Gene ID | 78926 |
Full Name | growth arrest-specific 2 like 1 |
Synonyms | 4930500E24Rik,D0Jmb1,Gar22,TU-71.1 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This gene encodes a member of the Gas2 family, actin-associated proteins expressed at high levels in growth-arrested cells. The gene expression is negatively regulated by serum and growth factors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]. |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
XM_030246437.1 | XP_030102297.1 | GAS2-like protein 1 isoform X1 |
XM_017314850.1 | XP_017170339.1 | GAS2-like protein 1 isoform X1 |
XM_017314850.2 | XP_017170339.1 | GAS2-like protein 1 isoform X1 |
NM_001190406.1 | NP_001177335.1 | GAS2-like protein 1 isoform gamma |
XM_017314849.1 | XP_017170338.1 | GAS2-like protein 1 isoform X1 |
NM_030228.3 | NP_084504.2 | GAS2-like protein 1 isoform alpha |
NM_001190408.1 | NP_001177337.1 | GAS2-like protein 1 isoform beta |
NM_144560.3 | NP_653146.1 | GAS2-like protein 1 isoform beta |

Homo sapiens (human) | GAS2L1 | NP_006469.2 |
LOC714530 | XP_002808011.1 | |
Mus musculus (house mouse) | Gas2l1 | NP_653146.1 |
Gallus gallus (chicken) | LOC100859584 | XP_003642278.1 |
Bos taurus (cattle) | GAS2L1 | NP_001077167.1 |
Canis lupus familiaris (dog) | GAS2L1 | XP_543468.2 |
Xenopus tropicalis (tropical clawed frog) | gas2l1 | XP_002934334.1 |

Related articles in PubMed
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
GAR22? regulates cell migration, sperm motility, and axoneme structure.
Gamper I, Fleck D, Barlin M, Spehr M, El Sayad S, Kleine H, Maxeiner S, Schalla C, Aydin G, Hoss M, Litchfield DW, L?scher B, Zenke M, Sechi A
Molecular biology of the cell27(2)277-94(2016 Jan)
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)
GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells.
Gamper I, Koh KR, Ruau D, Ullrich K, Bartunkova J, Piroth D, Hacker C, Bartunek P, Zenke M
Experimental hematology37(5)539-548.e4(2009 May)
Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules.
Goriounov D, Leung CL, Liem RK
Journal of cell science116(Pt 6)1045-58(2003 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Gas2l1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gas2l1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15709 | |
Clone ID Related Accession (Same CDS sequence) | NM_030228.3 | |
Accession Version | NM_030228.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform alpha | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK052229.1, AK019661.1 and BC098192.1. On Jun 19, 2010 this sequence version replaced NM_030228.2. Transcript Variant: This variant (alpha) represents the longest transcript and encodes isoform alpha. ##Evidence-Data-START## Transcript exon combination :: AK019661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849387, SAMN01164141 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_084504.2 |
CDS | 392..1426 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15728 | |
Clone ID Related Accession (Same CDS sequence) | XM_030246437.1 , XM_017314850.1 , XM_017314850.2 , NM_001190406.1 , XM_017314849.1 | |
Accession Version | NM_001190406.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform gamma | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK052229.1, AK082864.1, AK019661.1 and BC098192.1. Transcript Variant: This variant (gamma) differs in the 5' UTR, and lacks an exon that results in a frameshift in the 3' coding region, compared to variant alpha. The encoded isoform (gamma) has a distinct and shorter C-terminus, compared to isoform alpha. ##Evidence-Data-START## Transcript exon combination :: AK082864.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001177335.1 |
CDS | 134..997 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15728 | |
Clone ID Related Accession (Same CDS sequence) | XM_030246437.1 , XM_017314850.1 , XM_017314850.2 , NM_001190406.1 , XM_017314849.1 | |
Accession Version | XM_017314850.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170339.1 |
CDS | 156..1019 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15728 | |
Clone ID Related Accession (Same CDS sequence) | XM_030246437.1 , XM_017314850.1 , XM_017314850.2 , NM_001190406.1 , XM_017314849.1 | |
Accession Version | XM_017314849.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170338.1 |
CDS | 772..1635 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15728 | |
Clone ID Related Accession (Same CDS sequence) | XM_030246437.1 , XM_017314850.1 , XM_017314850.2 , NM_001190406.1 , XM_017314849.1 | |
Accession Version | XM_030246437.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030102297.1 |
CDS | 413..1276 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15728 | |
Clone ID Related Accession (Same CDS sequence) | XM_030246437.1 , XM_017314850.1 , XM_017314850.2 , NM_001190406.1 , XM_017314849.1 | |
Accession Version | XM_017314850.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017314850.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170339.1 |
CDS | 155..1018 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15697 | |
Clone ID Related Accession (Same CDS sequence) | NM_001190408.1 , NM_144560.3 | |
Accession Version | NM_001190408.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform beta | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645522.12 and AW061138.1. Transcript Variant: This variant (delta) differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant alpha, resulting in an isoform (beta) with a distinct and longer C-terminus, compared to isoform alpha. Both variants beta and delta encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC031785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849389 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001177337.1 |
CDS | 134..2170 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15697 | |
Clone ID Related Accession (Same CDS sequence) | NM_001190408.1 , NM_144560.3 | |
Accession Version | NM_144560.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | GAS2-like protein 1 isoform beta | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK052229.1, BY231632.1, AF508324.1 and AW061138.1. On Jun 19, 2010 this sequence version replaced NM_144560.2. Transcript Variant: This variant (beta) differs in the 3' coding region and 3' UTR, compared to variant alpha, resulting in an isoform (beta) with a distinct and longer C-terminus, compared to isoform alpha. Both variants beta and delta encode the same isoform. ##Evidence-Data-START## CDS exon combination :: BC031785.1, AF508324.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_653146.1 |
CDS | 392..2428 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGAACC CAGTGGCGGG CATCGCAGGC TCTGCCGCCA AGAGTGTGCG ACCCTTCCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
High-throughput discovery of novel developmental phenotypes. |
![]() |
GAR22? regulates cell migration, sperm motility, and axoneme structure. |
![]() |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
![]() |
GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells. |
![]() |
Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules. |