Zc4h2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zc4h2
Entrez Gene ID	367838
Full Name	zinc finger C4H2-type containing
Synonyms	RGD1561708
General protein information	Preferred Names zinc finger C4H2-type containing Names zinc finger C4H2 domain-containing protein zinc finger, C4H2 domain containing
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001126374.1	NP_001119846.1	zinc finger C4H2 domain-containing protein

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Zc4h2	NP_001119846.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010728	XP_311442.3
Xenopus tropicalis (tropical clawed frog)	zc4h2	NP_001016675.1
	ZC4H2	XP_001098245.1
Bos taurus (cattle)	ZC4H2	NP_001071579.1
Homo sapiens (human)	ZC4H2	NP_061154.1
Canis lupus familiaris (dog)	ZC4H2	XP_549040.3
Mus musculus (house mouse)	Zc4h2	NP_001003916.1
Gallus gallus (chicken)	ZC4H2	XP_420173.3
Danio rerio (zebrafish)	zc4h2	NP_955936.1
Pan troglodytes (chimpanzee)	ZC4H2	XP_521094.1
Drosophila melanogaster (fruit fly)	CG13001	NP_573181.1

Gene Ontology
Bibliography

Related articles in PubMed

ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons.
May M, Hwang KS, Miles J, Williams C, Niranjan T, Kahler SG, Chiurazzi P, Steindl K, Van Der Spek PJ, Swagemakers S, Mueller J, Stefl S, Alexov E, Ryu JI, Choi JH, Kim HT, Tarpey P, Neri G, Holloway L, Skinner C, Stevenson RE, Dorsky RI, Wang T, Schwartz CE, Kim CH
Human molecular genetics24(17)4848-61(2015 Sep)

ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.
Hirata H, Nanda I, van Riesen A, McMichael G, Hu H, Hambrock M, Papon MA, Fischer U, Marouillat S, Ding C, Alirol S, Bienek M, Preisler-Adams S, Grimme A, Seelow D, Webster R, Haan E, MacLennan A, Stenzel W, Yap TY, Gardner A, Nguyen LS, Shaw M, Lebrun N, Haas SA, Kress W, Haaf T, Schellenberger E, Chelly J, Viot G, Shaffer LG, Rosenfeld JA, Kramer N, Falk R, El-Khechen D, Escobar LF, Hennekam R, Wieacker P, H?bner C, Ropers HH, Gecz J, Schuelke M, Laumonnier F, Kalscheuer VM
American journal of human genetics92(5)681-95(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Zc4h2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zc4h2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01502	NM_001126374.1 Latest version!	Rattus norvegicus zinc finger C4H2-type containing (Zc4h2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zc4h2 ( NM_001126374.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001119846.1 Rattus norvegicus zinc finger C4H2-type containing (Zc4h2), mRNA.

Price & Availability↑

CloneID	ORa01502
Clone ID Related Accession (Same CDS sequence)	NM_001126374.1
Accession Version	NM_001126374.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-02-04
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger C4H2 domain-containing protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC162002.1. On or before May 8, 2008 this sequence version replaced XM_001067100.1, XM_346320.3. ##Evidence-Data-START## Transcript exon combination :: BC162002.1, EV771242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTAAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCTCATGTGG AGGAACTCCG ACTGATCCAT GCTGATATCA ATGTGATGGA AAACACCATT 
AAACAGTCTG AAAATGACTT AAACAAGCTG CTAGAGTCAA CCCGGAGGCT TCATGATGAG 
TATAAACCAC TGAAAGAACA TGTGGATGCC CTGCGCATGA CGTTGGGCCT GCAAAGGCTT 
CCTGACTTAT GTGAAGAGGA AGAGAAACTC TCCTTGGATT ACTTCGAGAA GCAGAAAGCA 
GAATGGCAGA CAGAACCTCA AGAACCCCCC ATACCCGAAT CCCTTGCCGC TGCAGCTGCT 
GCTGCTCAAC AACTCCAAGT GGCCAGGAAG CAGGACACGA GGCAGACAGC CACCTTCAGG 
CAGCAGCCTC CGCCTATGAA GGCCTGTTTG TCATGCCACC AACAGATTCA TCGAAATGCG 
CCTATATGTC CTCTTTGCAA AGCCAAGAGT CGGTCACGGA ACCCCAAAAA GCCAAAACGG 
AAGCAAGATG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001119846.1
CDS	120..794
Translation	MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Target ORF information:

RefSeq Version	NM_001126374.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger C4H2-type containing (Zc4h2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001126374.1

ORF Insert Sequence:

ATGGCAGATG AACAAGAAAT CATGTGCAAA TTGGAAAGCA TTAAAGAGAT CAGGAACAAG 
ACTCTGCAGA TGGAAAAGAT CAAGGCCCGT TTGAAGGCTG AGTTCGAGGC TCTGGAGTCT 
GAAGAGAGGC ACCTAAAAGA ATACAAACAG GAGATGGATC TCCTGCTACA GGAGAAGATG 
GCTCATGTGG AGGAACTCCG ACTGATCCAT GCTGATATCA ATGTGATGGA AAACACCATT 
AAACAGTCTG AAAATGACTT AAACAAGCTG CTAGAGTCAA CCCGGAGGCT TCATGATGAG 
TATAAACCAC TGAAAGAACA TGTGGATGCC CTGCGCATGA CGTTGGGCCT GCAAAGGCTT 
CCTGACTTAT GTGAAGAGGA AGAGAAACTC TCCTTGGATT ACTTCGAGAA GCAGAAAGCA 
GAATGGCAGA CAGAACCTCA AGAACCCCCC ATACCCGAAT CCCTTGCCGC TGCAGCTGCT 
GCTGCTCAAC AACTCCAAGT GGCCAGGAAG CAGGACACGA GGCAGACAGC CACCTTCAGG 
CAGCAGCCTC CGCCTATGAA GGCCTGTTTG TCATGCCACC AACAGATTCA TCGAAATGCG 
CCTATATGTC CTCTTTGCAA AGCCAAGAGT CGGTCACGGA ACCCCAAAAA GCCAAAACGG 
AAGCAAGATG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons.
Human molecular genetics24(17)4848-61(2015 Sep)
May M,Hwang KS,Miles J,Williams C,Niranjan T,Kahler SG,Chiurazzi P,Steindl K,Van Der Spek PJ,Swagemakers S,Mueller J,Stefl S,Alexov E,Ryu JI,Choi JH,Kim HT,Tarpey P,Neri G,Holloway L,Skinner C,Stevenson RE,Dorsky RI,Wang T,Schwartz CE,Kim CH

ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.
American journal of human genetics92(5)681-95(2013 May)
Hirata H,Nanda I,van Riesen A,McMichael G,Hu H,Hambrock M,Papon MA,Fischer U,Marouillat S,Ding C,Alirol S,Bienek M,Preisler-Adams S,Grimme A,Seelow D,Webster R,Haan E,MacLennan A,Stenzel W,Yap TY,Gardner A,Nguyen LS,Shaw M,Lebrun N,Haas SA,Kress W,Haaf T,Schellenberger E,Chelly J,Viot G,Shaffer LG,Rosenfeld JA,Kramer N,Falk R,El-Khechen D,Escobar LF,Hennekam R,Wieacker P,H?bner C,Ropers HH,Gecz J,Schuelke M,Laumonnier F,Kalscheuer VM

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Zc4h2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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