About the MAPK signaling pathway pathway
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
424 gene Click for more »
| Gene Symbol | Full Name |
|---|---|
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| FAS | Fas cell surface death receptor |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| ARRB1 | arrestin, beta 1 |
| ARRB2 | arrestin, beta 2 |
| ATF4 | activating transcription factor 4 |
| BDNF | brain-derived neurotrophic factor |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CACNA1B | calcium channel, voltage-dependent, N type, alpha 1B subunit |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CACNA1E | calcium channel, voltage-dependent, R type, alpha 1E subunit |
| CACNA1F | calcium channel, voltage-dependent, L type, alpha 1F subunit |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CD14 | CD14 molecule |
| CDC25B | cell division cycle 25B |
| CDC42 | cell division cycle 42 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| ATF2 | activating transcription factor 2 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| MAPK14 | mitogen-activated protein kinase 14 |
| DAXX | death-domain associated protein |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP3 | dual specificity phosphatase 3 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| DUSP7 | dual specificity phosphatase 7 |
| DUSP8 | dual specificity phosphatase 8 |
| DUSP9 | dual specificity phosphatase 9 |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| ELK1 | ELK1, member of ETS oncogene family |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| MECOM | MDS1 and EVI1 complex locus |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGF3 | fibroblast growth factor 3 |
| FGF4 | fibroblast growth factor 4 |
| FGF5 | fibroblast growth factor 5 |
| FGF6 | fibroblast growth factor 6 |
| FGF7 | fibroblast growth factor 7 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FGF9 | fibroblast growth factor 9 |
| FGF10 | fibroblast growth factor 10 |
| FGF11 | fibroblast growth factor 11 |
| FGF12 | fibroblast growth factor 12 |
| FGF13 | fibroblast growth factor 13 |
| FGF14 | fibroblast growth factor 14 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FLNA | filamin A, alpha |
| FLNB | filamin B, beta |
| FLNC | filamin C, gamma |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| GRB2 | growth factor receptor-bound protein 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1B | heat shock 70kDa protein 1B |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL1A | interleukin 1, alpha |
| IL1B | interleukin 1, beta |
| IL1R1 | interleukin 1 receptor, type I |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| STMN1 | stathmin 1 |
| MAPT | microtubule-associated protein tau |
| MAX | MYC associated factor X |
| MEF2C | myocyte enhancer factor 2C |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 |
| MOS | v-mos Moloney murine sarcoma viral oncogene homolog |
