Snai1 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Snai1 |
| Entrez Gene ID | 116490 |
| Full Name | snail family transcriptional repressor 1 |
| Synonyms | Sna |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | mouse homolog regulates cell cycle progression and may play a role in epithelial-mesenchymal transitions [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_053805.1 | NP_446257.1 | zinc finger protein SNAI1 |
| SNAI1 | XP_001097698.1 | |
| Bos taurus (cattle) | SNAI1 | NP_001106179.1 |
| Pan troglodytes (chimpanzee) | SNAI1 | XP_001151765.1 |
| Mus musculus (house mouse) | Snai1 | NP_035557.1 |
| Rattus norvegicus (Norway rat) | Snai1 | NP_446257.1 |
| Homo sapiens (human) | SNAI1 | NP_005976.2 |
| Canis lupus familiaris (dog) | SNAI1 | XP_005635224.1 |
Related articles in PubMed
HIF-1? regulates EMT via the Snail and ?-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis.
Zhu Y, Tan J, Xie H, Wang J, Meng X, Wang R
Journal of cellular and molecular medicine20(4)688-97(2016 Apr)
Syntenin regulates TGF-?1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-? type I receptor internalization.
Hwangbo C, Tae N, Lee S, Kim O, Park OK, Kim J, Kwon SH, Lee JH
Oncogene35(3)389-401(2016 Jan)
MiR-30a regulates the atrial fibrillation-induced myocardial fibrosis by targeting snail 1.
Yuan CT, Li XX, Cheng QJ, Wang YH, Wang JH, Liu CL
International journal of clinical and experimental pathology8(12)15527-36(2015)
Transcription factor snail regulates tumor necrosis factor ?-mediated synovial fibroblast activation in the rheumatoid joint.
Chen SY, Shiau AL, Li YT, Lin CC, Jou IM, Liu MF, Wu CL, Wang CR
Arthritis & rheumatology (Hoboken, N.J.)67(1)39-50(2015 Jan)
Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine.
Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, Gonz?lez-Cuevas J, Hern?ndez-Ortega LD, Armend?riz-Borunda J
World journal of gastroenterology19(47)9020-33(2013 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
HIF-1A regulates epithelial-mesenchymal transition via the Snail and beta-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis.
Title: HIF-1? regulates EMT via the Snail and ?-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis.
Suggest that miR-30a target snail 1 protein may be related to atrial fibrillation-induced myocardial fibrosis.
Title: MiR-30a regulates the atrial fibrillation-induced myocardial fibrosis by targeting snail 1.
Transcription factor snail regulates tumor necrosis factor alpha-mediated synovial fibroblast activation in the rheumatoid joint.
Title: Transcription factor snail regulates tumor necrosis factor ?-mediated synovial fibroblast activation in the rheumatoid joint.
Caffeine inhibits the transcriptional factor Snail-1, down-regulating profibrogenic genes, and activates Nrf2 inducing antioxidant enzymes system, preventing inflammation and fibrosis.
Title: Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine.
miR-30a negatively regulates Snai1-mediated EMT during peritoneal fibrosis in vitro and in vivo.
Title: miR-30a negatively regulates TGF-?1-induced epithelial-mesenchymal transition and peritoneal fibrosis by targeting Snai1.
The following Snai1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snai1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa12351 | |
| Clone ID Related Accession (Same CDS sequence) | NM_053805.1 | |
| Accession Version | NM_053805.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2020-01-04 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | zinc finger protein SNAI1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079210.1. On Apr 19, 2005 this sequence version replaced XM_342587.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079210.1, EV777950.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCCGCGCT CCTTCCTGGT CAGGAAGCCG TCCGACCCCC GCCGGAAGCC CAACTATAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_446257.1 |
| CDS | 81..875 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_053805.1 |
ORF Insert Sequence:
1 | ATGCCGCGCT CCTTCCTGGT CAGGAAGCCG TCCGACCCCC GCCGGAAGCC CAACTATAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
HIF-1? regulates EMT via the Snail and ?-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis. |
|
Syntenin regulates TGF-?1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-? type I receptor internalization. |
|
MiR-30a regulates the atrial fibrillation-induced myocardial fibrosis by targeting snail 1. |
|
Transcription factor snail regulates tumor necrosis factor ?-mediated synovial fibroblast activation in the rheumatoid joint. |
|
Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine. |