Gene Symbol | Slc9a4 |
Entrez Gene ID | 24785 |
Full Name | solute carrier family 9 member A4 |
Synonyms | Nhe4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Slc9a4 cDNA ORF clone
Gene Symbol | Slc9a4 |
Entrez Gene ID | 24785 |
Full Name | solute carrier family 9 member A4 |
Synonyms | Nhe4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006244738.3 | XP_006244800.1 | sodium/hydrogen exchanger 4 isoform X1 |
XM_008766991.2 | XP_008765213.1 | sodium/hydrogen exchanger 4 isoform X2 |
NM_173098.1 | NP_775121.1 | sodium/hydrogen exchanger 4 precursor |
Pan troglodytes (chimpanzee) | SLC9A4 | XP_001163482.1 |
Bos taurus (cattle) | SLC9A4 | XP_002691230.1 |
Xenopus tropicalis (tropical clawed frog) | slc9a4 | XP_002934548.2 |
SLC9A4 | XP_001108212.1 | |
Rattus norvegicus (Norway rat) | Slc9a4 | NP_775121.1 |
Gallus gallus (chicken) | SLC9A4 | NP_001244184.1 |
Homo sapiens (human) | SLC9A4 | NP_001011552.2 |
Canis lupus familiaris (dog) | SLC9A4 | XP_003431565.1 |
Mus musculus (house mouse) | Slc9a4 | NP_796058.1 |
Enhanced Expression of Sodium Hydrogen Exchanger (NHE)-1, 2 and 4 in the Cervix of Ovariectomised Rats by Phytoestrogen Genistein.
Ismail N, Giribabu N, Muniandy S, Salleh N
International journal of medical sciences12(6)468-77(2015)
Differential expression of Na+/H+-exchanger (NHE-1, 2, and 4) proteins and mRNA in rodent's uterus under sex steroid effect and at different phases of the oestrous cycle.
Gholami K, Muniandy S, Salleh N
BioMed research international2013840121(2013)
Functional role of NHE4 as a pH regulator in rat and human colonic crypts.
Arena EA, Longo WE, Roberts KE, Geibel P, Nateqi J, Brandstetter M, Geibel JP
American journal of physiology. Cell physiology302(2)C412-8(2012 Jan)
Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger.
Gawenis LR, Greeb JM, Prasad V, Grisham C, Sanford LP, Doetschman T, Andringa A, Miller ML, Shull GE
The Journal of biological chemistry280(13)12781-9(2005 Apr)
Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins.
Orlowski J, Kandasamy RA, Shull GE
The Journal of biological chemistry267(13)9331-9(1992 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Enhanced expression of NHE-1, 2 and 4 proteins and mRNAs expression in cervix under genistein influence could help to restore the cervicovaginal fluid pH that might help to prevent cervicovaginal complications related to menopause
Title: Enhanced Expression of Sodium Hydrogen Exchanger (NHE)-1, 2 and 4 in the Cervix of Ovariectomised Rats by Phytoestrogen Genistein.
Differential expressions of uterine NHE isoforms 1, 2, and 4 could explain the observed changes in the uterine fluid pH under sex steroid effect and at different phases of the oestrous cycle
Title: Differential expression of Na+/H+-exchanger (NHE-1, 2, and 4) proteins and mRNA in rodent's uterus under sex steroid effect and at different phases of the oestrous cycle.
Data demonstrate functional NHE4 activity in the rat and human colon and suggest that this exchanger is capable of modulating intracellular pH over a wide pH spectrum and may play an important role in maintaining cellular pH homeostasis.
Title: Functional role of NHE4 as a pH regulator in rat and human colonic crypts.
The following Slc9a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc9a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa03359 | |
Clone ID Related Accession (Same CDS sequence) | NM_173098.1 | |
Accession Version | NM_173098.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sodium/hydrogen exchanger 4 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M85301.1. ##Evidence-Data-START## Transcript exon combination :: M85301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGTCCTG CAATGTTGAG AGCTTTTAGT TCGTGGAAAT GGTTGCTATT GCTGATGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_775121.1 |
CDS | 467..2620 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173098.1 |
1 | ATGGGTCCTG CAATGTTGAG AGCTTTTAGT TCGTGGAAAT GGTTGCTATT GCTGATGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa32109 | |
Clone ID Related Accession (Same CDS sequence) | XM_006244738.3 | |
Accession Version | XM_006244738.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2394bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sodium/hydrogen exchanger 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006244738.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGTCCTG CAATGTTGAG AGCTTTTAGT TCGTGGAAAT GGTTGCTATT GCTGATGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006244800.1 |
CDS | 606..2999 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006244738.3 |
1 | ATGGGTCCTG CAATGTTGAG AGCTTTTAGT TCGTGGAAAT GGTTGCTATT GCTGATGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa42957 | |
Clone ID Related Accession (Same CDS sequence) | XM_008766991.2 | |
Accession Version | XM_008766991.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2106bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sodium/hydrogen exchanger 4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008766991.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAGAGA GCTGCCTCCT CATCATCGTG GGAGCCTTGG TGGGCAGCAT CATTTTTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008765213.1 |
CDS | 52..2157 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008766991.2 |
1 | ATGCCAGAGA GCTGCCTCCT CATCATCGTG GGAGCCTTGG TGGGCAGCAT CATTTTTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Enhanced Expression of Sodium Hydrogen Exchanger (NHE)-1, 2 and 4 in the Cervix of Ovariectomised Rats by Phytoestrogen Genistein. |
Differential expression of Na+/H+-exchanger (NHE-1, 2, and 4) proteins and mRNA in rodent's uterus under sex steroid effect and at different phases of the oestrous cycle. |
Functional role of NHE4 as a pH regulator in rat and human colonic crypts. |
Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. |
Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. |