Gene Symbol | Naa50 |
Entrez Gene ID | 288108 |
Full Name | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
Synonyms | Mak3,Nat13 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Naa50 cDNA ORF clone
Gene Symbol | Naa50 |
Entrez Gene ID | 288108 |
Full Name | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
Synonyms | Mak3,Nat13 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001105881.2 | NP_001099351.1 | N-alpha-acetyltransferase 50 isoform 2 |
NM_001309804.1 | NP_001296733.1 | N-alpha-acetyltransferase 50 isoform 1 |
Canis lupus familiaris (dog) | NAA50 | XP_003640176.1 |
Gallus gallus (chicken) | NAA50 | NP_001025949.1 |
Xenopus tropicalis (tropical clawed frog) | naa50 | NP_001011131.1 |
Bos taurus (cattle) | NAA50 | NP_001069218.1 |
Homo sapiens (human) | NAA50 | NP_079422.1 |
Pan troglodytes (chimpanzee) | NAA50 | XP_526267.3 |
NAA50 | XP_002802699.1 | |
Rattus norvegicus (Norway rat) | Naa50 | NP_001099351.1 |
Mus musculus (house mouse) | Naa50 | NP_082384.1 |
Danio rerio (zebrafish) | naa50 | NP_001003623.1 |
Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY.
Reddi R, Saddanapu V, Chinthapalli DK, Sankoju P, Sripadi P, Addlagatta A
The Journal of biological chemistry291(39)20530-8(2016 09)
Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion.
Rong Z, Ouyang Z, Magin RS, Marmorstein R, Yu H
The Journal of biological chemistry291(36)19079-91(2016 09)
An organellar n?-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.
Aksnes H, Van Damme P, Goris M, Starheim KK, Marie M, St?ve SI, Hoel C, Kalvik TV, Hole K, Glomnes N, Furnes C, Ljostveit S, Ziegler M, Niere M, Gevaert K, Arnesen T
Cell reports10(8)1362-74(2015 Mar)
Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study.
Evjenth RH, Brenner AK, Thompson PR, Arnesen T, Fr?ystein N?, Lillehaug JR
The Journal of biological chemistry287(13)10081-8(2012 Mar)
Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation.
Liszczak G, Arnesen T, Marmorstein R
The Journal of biological chemistry286(42)37002-10(2011 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Naa50 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Naa50 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa04370 | |
Clone ID Related Accession (Same CDS sequence) | NM_001105881.2 | |
Accession Version | NM_001105881.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-31 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-alpha-acetyltransferase 50 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07034274.1. On Jun 12, 2015 this sequence version replaced NM_001105881.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region. The encoded isoform (2) is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AW525826.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAAGGCC GGATCGAGCT GGGAGATGTG ACACCCCACA ATATTAAACA GTTGAAGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099351.1 |
CDS | 292..798 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001105881.2 |
1 | ATGAAAGGCC GGATCGAGCT GGGAGATGTG ACACCCCACA ATATTAAACA GTTGAAGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa34265 | |
Clone ID Related Accession (Same CDS sequence) | NM_001309804.1 | |
Accession Version | NM_001309804.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 510bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-31 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-alpha-acetyltransferase 50 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC169000.1. On Jun 12, 2015 this sequence version replaced XM_006248326.2. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC169000.1, FQ216855.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAAGGTA GCCGGATCGA GCTGGGAGAT GTGACACCCC ACAATATTAA ACAGTTGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001296733.1 |
CDS | 292..801 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001309804.1 |
1 | ATGAAAGGTA GCCGGATCGA GCTGGGAGAT GTGACACCCC ACAATATTAA ACAGTTGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY. |
Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. |
An organellar n?-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity. |
Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study. |
Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation. |