Pa2g4 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Pa2g4 |
| Entrez Gene ID | 288778 |
| Full Name | proliferation-associated 2G4 |
| Synonyms | Ebp1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | human and mouse homologs may be involved in coordinating ribosome biosynthesis and cell proliferation [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001004206.1 | NP_001004206.1 | proliferation-associated protein 2G4 |
| Bos taurus (cattle) | PA2G4 | NP_001029871.1 |
| Drosophila melanogaster (fruit fly) | CG10576 | NP_647984.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005108 | XP_313985.4 |
| Caenorhabditis elegans (roundworm) | W08E12.7 | NP_500311.1 |
| Magnaporthe oryzae (rice blast fungus) | MGG_06316 | XP_003717269.1 |
| Danio rerio (zebrafish) | pa2g4b | NP_997806.1 |
| Arabidopsis thaliana (thale cress) | ATG2 | NP_001190060.1 |
| Pan troglodytes (chimpanzee) | PA2G4 | NP_001233412.1 |
| Canis lupus familiaris (dog) | PA2G4 | XP_531629.2 |
| Neurospora crassa | NCU00422 | XP_956686.1 |
| Oryza sativa (rice) | Os05g0350500 | NP_001055274.1 |
| Homo sapiens (human) | PA2G4 | NP_006182.2 |
| Mus musculus (house mouse) | Pa2g4 | NP_035249.1 |
| Rattus norvegicus (Norway rat) | Pa2g4 | NP_001004206.1 |
| Gallus gallus (chicken) | PA2G4 | XP_423059.4 |
| Danio rerio (zebrafish) | pa2g4a | NP_001002070.1 |
| Schizosaccharomyces pombe (fission yeast) | cdb4 | NP_593397.1 |
| Xenopus tropicalis (tropical clawed frog) | pa2g4 | NP_001008439.1 |
Related articles in PubMed
Upregulated expression of ebp1 contributes to schwann cell differentiation and migration after sciatic nerve crush.
Liu Y, Liu Y, Cao J, Zhu X, Nie X, Yao L, Chen M, Cheng X, Wang Y
Journal of molecular neuroscience : MN54(4)602-13(2014 Dec)
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.
Liu Z, Oh SM, Okada M, Liu X, Cheng D, Peng J, Brat DJ, Sun SY, Zhou W, Gu W, Ye K
Molecular biology of the cell20(3)757-68(2009 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Ebp1 was upregulated in Schwann cells following sciatic nerve crush.
Title: Upregulated expression of ebp1 contributes to schwann cell differentiation and migration after sciatic nerve crush.
B23 distinctively binds Ebp1 isoforms and regulates cell proliferation and survival through p42 and p48, respectively.
Title: Ebp1 association with nucleophosmin/B23 is essential for regulating cell proliferation and suppressing apoptosis.
PKC-delta antagonizes apoptosis through phosphorylating Ebp1 and protects it from apoptotic degradation.
Title: Protein kinase C-delta phosphorylates Ebp1 and prevents its proteolytic degradation, enhancing cell survival.
Ebp1 might regulate cell survival and differentiation through two distinctive p48 and p42 isoforms.
Title: Ebp1 isoforms distinctively regulate cell survival and differentiation.
Results suggest that Ebp1 contributes to inhibition of DNA fragmentation by caspase-activated DNase, and that nuclear Akt might contribute to suppressing apoptosis through interaction with Ebp1.
Title: Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase.
The following Pa2g4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pa2g4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa10071 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001004206.1 | |
| Accession Version | NM_001004206.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | proliferation-associated protein 2G4 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079095.1. On Sep 10, 2004 this sequence version replaced XM_213828.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCGGGCG AAGACGAGCA GCAGGAGCAA ACTATCGCCG AGGACCTGGT CGTGACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001004206.1 |
| CDS | 121..1305 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001004206.1 |
ORF Insert Sequence:
1 | ATGTCGGGCG AAGACGAGCA GCAGGAGCAA ACTATCGCCG AGGACCTGGT CGTGACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Upregulated expression of ebp1 contributes to schwann cell differentiation and migration after sciatic nerve crush. |
|
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. |
|
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. |
|
Defining the membrane proteome of NK cells. |
|
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. |