Pa2g4 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Pa2g4 |
| Entrez Gene ID | 18813 |
| Full Name | proliferation-associated 2G4 |
| Synonyms | 38kDa,AA672939,Ebp1,Plfap |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_011119.3 | NP_035249.1 | proliferation-associated protein 2G4 |
| Bos taurus (cattle) | PA2G4 | NP_001029871.1 |
| Drosophila melanogaster (fruit fly) | CG10576 | NP_647984.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005108 | XP_313985.4 |
| Caenorhabditis elegans (roundworm) | W08E12.7 | NP_500311.1 |
| Magnaporthe oryzae (rice blast fungus) | MGG_06316 | XP_003717269.1 |
| Danio rerio (zebrafish) | pa2g4b | NP_997806.1 |
| Arabidopsis thaliana (thale cress) | ATG2 | NP_001190060.1 |
| Pan troglodytes (chimpanzee) | PA2G4 | NP_001233412.1 |
| Canis lupus familiaris (dog) | PA2G4 | XP_531629.2 |
| Neurospora crassa | NCU00422 | XP_956686.1 |
| Oryza sativa (rice) | Os05g0350500 | NP_001055274.1 |
| Homo sapiens (human) | PA2G4 | NP_006182.2 |
| Mus musculus (house mouse) | Pa2g4 | NP_035249.1 |
| Rattus norvegicus (Norway rat) | Pa2g4 | NP_001004206.1 |
| Gallus gallus (chicken) | PA2G4 | XP_423059.4 |
| Danio rerio (zebrafish) | pa2g4a | NP_001002070.1 |
| Schizosaccharomyces pombe (fission yeast) | cdb4 | NP_593397.1 |
| Xenopus tropicalis (tropical clawed frog) | pa2g4 | NP_001008439.1 |
Related articles in PubMed
ERBB3-Binding Protein (EBP1) is a novel DPPA4 cofactor in human pluripotent cells.
Somanath P, Bush KM, Knoepfler PS
Stem cells (Dayton, Ohio)(2018 Jan)
A polybasic motif in ErbB3-binding protein 1 (EBP1) has key functions in nucleolar localization and polyphosphoinositide interaction.
Karlsson T, Altankhuyag A, Dobrovolska O, Turcu DC, Lewis AE
The Biochemical journal473(14)2033-47(2016 07)
P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.
Ko HR, Kim CK, Lee SB, Song J, Lee KH, Kim KK, Park KW, Cho SW, Ahn JY
Cell death & disease5e1131(2014 Mar)
ErbB3 binding protein-1 (Ebp1) controls proliferation and myogenic differentiation of muscle stem cells.
Figeac N, Serralbo O, Marcelle C, Zammit PS
Developmental biology386(1)135-51(2014 Feb)
EBP1, a novel host factor involved in primer binding site-dependent restriction of moloney murine leukemia virus in embryonic cells.
Wang GZ, Wolf D, Goff SP
Journal of virology88(3)1825-9(2014 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results show that EBP1 interacts directly with PPIns and associate with PtdIns(3,4,5)P3 in the nucleolus.
Title: A polybasic motif in ErbB3-binding protein 1 (EBP1) has key functions in nucleolar localization and polyphosphoinositide interaction.
Ebp1 p42 isoform regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.
Title: P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.
Ebp1 has a role in the regulation of embryonic muscle progenitors and adult muscle stem cells, which likely operates independently of ErbB3 signaling
Title: ErbB3 binding protein-1 (Ebp1) controls proliferation and myogenic differentiation of muscle stem cells.
EBP1 is a novel component of the ZFP809-TRIM28 silencing complex to restrict the moloney murine leukemia virus replication in embryonic cells.
Title: EBP1, a novel host factor involved in primer binding site-dependent restriction of moloney murine leukemia virus in embryonic cells.
IGF-1 production and IGBP-3 and 4 protein levels were reduced in both embryo fibroblasts and adult knock-out mice. The proliferation of fibroblasts derived from Day 12.5 knock out embryos was also decreased as compared to that of wild type cells.
Title: Alterations in cell growth and signaling in ErbB3 binding protein-1 (Ebp1) deficient mice.
The following Pa2g4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pa2g4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu18186 | |
| Clone ID Related Accession (Same CDS sequence) | NM_011119.3 | |
| Accession Version | NM_011119.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Mus musculus(house mouse) | |
| Product | proliferation-associated protein 2G4 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK168582.1. On Apr 6, 2007 this sequence version replaced NM_011119.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK168582.1, AK144645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCGGGCG AAGACGAGCA GCAGGAGCAA ACTATCGCCG AGGACCTGGT CGTGACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_035249.1 |
| CDS | 108..1292 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_011119.3 |
ORF Insert Sequence:
1 | ATGTCGGGCG AAGACGAGCA GCAGGAGCAA ACTATCGCCG AGGACCTGGT CGTGACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
ERBB3-Binding Protein (EBP1) is a novel DPPA4 cofactor in human pluripotent cells. |
|
A polybasic motif in ErbB3-binding protein 1 (EBP1) has key functions in nucleolar localization and polyphosphoinositide interaction. |
|
P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP. |
|
ErbB3 binding protein-1 (Ebp1) controls proliferation and myogenic differentiation of muscle stem cells. |
|
EBP1, a novel host factor involved in primer binding site-dependent restriction of moloney murine leukemia virus in embryonic cells. |