Gene Symbol | Prkd2 |
Entrez Gene ID | 292658 |
Full Name | protein kinase D2 |
Synonyms | RGD1308054 |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Prkd2 cDNA ORF clone
gRNAs
Gene Symbol | Prkd2 |
Entrez Gene ID | 292658 |
Full Name | protein kinase D2 |
Synonyms | RGD1308054 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001013895.1 | NP_001013917.1 | serine/threonine-protein kinase D2 |
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.
Cobbaut M, Derua R, D?ppler H, Lou HJ, Vandoninck S, Storz P, Turk BE, Seufferlein T, Waelkens E, Janssens V, Van Lint J
Scientific reports7(1)887(2017 Apr)
Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).
Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E
The Journal of biological chemistry291(34)17988-8005(2016 08)
Protein kinase D regulates RhoA activity via rhotekin phosphorylation.
Pusapati GV, Eiseler T, Rykx A, Vandoninck S, Derua R, Waelkens E, Van Lint J, von Wichert G, Seufferlein T
The Journal of biological chemistry287(12)9473-83(2012 Mar)
Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells.
Matthews SA, Navarro MN, Sinclair LV, Emslie E, Feijoo-Carnero C, Cantrell DA
The Biochemical journal432(1)153-63(2010 Nov)
Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.
Evans IM, Bagherzadeh A, Charles M, Raynham T, Ireson C, Boakes A, Kelland L, Zachary IC
The Biochemical journal429(3)565-72(2010 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
siRNA-mediated knockdown of PKD1, PKD2, and PKD3 markedly attenuated YAP nuclear-cytoplasmic shuttling, phosphorylation at Ser(127), and induction of Ctgf and Areg expression in response to GPCR activation.
Title: Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).
The following Prkd2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prkd2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa04114 | |
Clone ID Related Accession (Same CDS sequence) | NM_001013895.1 | |
Accession Version | NM_001013895.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | serine/threonine-protein kinase D2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083592.1. On Apr 20, 2005 this sequence version replaced XM_214834.3. Sequence Note: This sequence has been modified as follows: removed 36 bp suspected to be vector contamination from the 3' end. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083592.1, FQ218070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGCCG CCCCCTCCCA TCCCGCCGGA CTCCCCTGCT CTCCGGGGCC CGGGTCTCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001013917.1 |
CDS | 157..2784 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCCGCCG CCCCCTCCCA TCCCGCCGGA CTCCCCTGCT CTCCGGGGCC CGGGTCTCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop. |
Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). |
Protein kinase D regulates RhoA activity via rhotekin phosphorylation. |
Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells. |
Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells. |