Rgs9 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Rgs9 |
| Entrez Gene ID | 29481 |
| Full Name | regulator of G-protein signaling 9 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | splice variant Rgs9l may act as a GTPase activating protein; inhibits dopamine D2 receptor induced G protein-coupled inward rectifier K+ channel current [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_019224.2 | NP_062097.1 | regulator of G-protein signaling 9 |
| Homo sapiens (human) | RGS9 | NP_003826.2 |
| Gallus gallus (chicken) | RGS9 | XP_415685.4 |
| RGS9 | XP_002800619.1 | |
| Canis lupus familiaris (dog) | RGS9 | XP_005624331.1 |
| Mus musculus (house mouse) | Rgs9 | NP_035398.2 |
| Rattus norvegicus (Norway rat) | Rgs9 | NP_062097.1 |
| Pan troglodytes (chimpanzee) | RGS9 | XP_511633.2 |
| Danio rerio (zebrafish) | rgs9b | NP_957124.2 |
Related articles in PubMed
The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration.
Sun H, Calipari ES, Beveridge TJ, Jones SR, Chen R
Neuroscience307253-61(2015 Oct)
Light-induced translocation of RGS9-1 and G?5L in mouse rod photoreceptors.
Tian M, Zallocchi M, Wang W, Chen CK, Palczewski K, Delimont D, Cosgrove D, Peng YW
PloS one8(3)e58832(2013)
Photoreceptor signaling: supporting vision across a wide range of light intensities.
Arshavsky VY, Burns ME
The Journal of biological chemistry287(3)1620-6(2012 Jan)
The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model.
Yin LL, Geng XC, Zhu XZ
Brain research bulletin86(5-6)367-72(2011 Nov)
Association between regulator of G protein signaling 9-2 and body weight.
Waugh JL, Celver J, Sharma M, Dufresne RL, Terzi D, Risch SC, Fairbrother WG, Neve RL, Kane JP, Malloy MJ, Pullinger CR, Gu HF, Tsatsanis C, Hamilton SP, Gold SJ, Zachariou V, Kovoor A
PloS one6(11)e27984(2011)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
RGS9 expression in striatum may involve in the abnormal involuntary movements induced by l-DOPA therapy
Title: The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model.
These studies with humans, rats and mice implicate RGS9-2 as a factor in regulating body weight.
Title: Association between regulator of G protein signaling 9-2 and body weight.
This study demonstrates that ontogenetic quinpirole treatment, which results in priming of the D(2) receptor, results in significant decreases in Rgs9, which has been shown to regulate G-protein coupling to D(2) receptors.
Title: Ontogenetic quinpirole treatment produces long-lasting decreases in the expression of Rgs9, but increases Rgs17 in the striatum, nucleus accumbens and frontal cortex.
Evidence for the involvement of ERbeta and RGS9-2 in 17-beta estradiol enhancement of amphetamine-induced place preference behavior.
Title: Evidence for the involvement of ERbeta and RGS9-2 in 17-beta estradiol enhancement of amphetamine-induced place preference behavior.
These data suggest that RGS9 is differentially expressed with age. Such differential expression may play an important role in neuronal differentiation and development as well as in neuronal function, such as dopamine and opioid signaling.
Title: Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats.
The following Rgs9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rgs9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa04086 | |
| Clone ID Related Accession (Same CDS sequence) | NM_019224.2 | |
| Accession Version | NM_019224.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-21 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | regulator of G-protein signaling 9 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB019145.1. On Feb 21, 2013 this sequence version replaced NM_019224.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB019145.1, AF071475.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGACGATCC GACACCAAGG CCAGCAGTAC AGGCCGAGGA TGGCATTTCT TCAAAAGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_062097.1 |
| CDS | 124..2157 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_019224.2 |
ORF Insert Sequence:
1 | ATGACGATCC GACACCAAGG CCAGCAGTAC AGGCCGAGGA TGGCATTTCT TCAAAAGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration. |
|
Light-induced translocation of RGS9-1 and G?5L in mouse rod photoreceptors. |
|
Photoreceptor signaling: supporting vision across a wide range of light intensities. |
|
The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model. |
|
Association between regulator of G protein signaling 9-2 and body weight. |