Rgs9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rgs9
Entrez Gene ID	29481
Full Name	regulator of G-protein signaling 9
General protein information	Preferred Names regulator of G-protein signaling 9 Names regulator of G-protein signaling 9
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1
Summary	splice variant Rgs9l may act as a GTPase activating protein; inhibits dopamine D2 receptor induced G protein-coupled inward rectifier K+ channel current [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019224.2	NP_062097.1	regulator of G-protein signaling 9

Pathways from BioSystems

Homologies

Homo sapiens (human)	RGS9	NP_003826.2
Gallus gallus (chicken)	RGS9	XP_415685.4
	RGS9	XP_002800619.1
Canis lupus familiaris (dog)	RGS9	XP_005624331.1
Mus musculus (house mouse)	Rgs9	NP_035398.2
Rattus norvegicus (Norway rat)	Rgs9	NP_062097.1
Pan troglodytes (chimpanzee)	RGS9	XP_511633.2
Danio rerio (zebrafish)	rgs9b	NP_957124.2

Gene Ontology
Bibliography

Related articles in PubMed

The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration.
Sun H, Calipari ES, Beveridge TJ, Jones SR, Chen R
Neuroscience307253-61(2015 Oct)

Light-induced translocation of RGS9-1 and G?5L in mouse rod photoreceptors.
Tian M, Zallocchi M, Wang W, Chen CK, Palczewski K, Delimont D, Cosgrove D, Peng YW
PloS one8(3)e58832(2013)

Photoreceptor signaling: supporting vision across a wide range of light intensities.
Arshavsky VY, Burns ME
The Journal of biological chemistry287(3)1620-6(2012 Jan)

The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model.
Yin LL, Geng XC, Zhu XZ
Brain research bulletin86(5-6)367-72(2011 Nov)

Association between regulator of G protein signaling 9-2 and body weight.
Waugh JL, Celver J, Sharma M, Dufresne RL, Terzi D, Risch SC, Fairbrother WG, Neve RL, Kane JP, Malloy MJ, Pullinger CR, Gu HF, Tsatsanis C, Hamilton SP, Gold SJ, Zachariou V, Kovoor A
PloS one6(11)e27984(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RGS9 expression in striatum may involve in the abnormal involuntary movements induced by l-DOPA therapy
Title: The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model.

These studies with humans, rats and mice implicate RGS9-2 as a factor in regulating body weight.
Title: Association between regulator of G protein signaling 9-2 and body weight.

This study demonstrates that ontogenetic quinpirole treatment, which results in priming of the D(2) receptor, results in significant decreases in Rgs9, which has been shown to regulate G-protein coupling to D(2) receptors.
Title: Ontogenetic quinpirole treatment produces long-lasting decreases in the expression of Rgs9, but increases Rgs17 in the striatum, nucleus accumbens and frontal cortex.

Evidence for the involvement of ERbeta and RGS9-2 in 17-beta estradiol enhancement of amphetamine-induced place preference behavior.
Title: Evidence for the involvement of ERbeta and RGS9-2 in 17-beta estradiol enhancement of amphetamine-induced place preference behavior.

These data suggest that RGS9 is differentially expressed with age. Such differential expression may play an important role in neuronal differentiation and development as well as in neuronal function, such as dopamine and opioid signaling.
Title: Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats.

The following Rgs9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rgs9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04086	NM_019224.2 Latest version!	Rattus norvegicus regulator of G-protein signaling 9 (Rgs9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rgs9 ( NM_019224.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062097.1 Rattus norvegicus regulator of G-protein signaling 9 (Rgs9), mRNA.

Price & Availability↑

CloneID	ORa04086
Clone ID Related Accession (Same CDS sequence)	NM_019224.2
Accession Version	NM_019224.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	regulator of G-protein signaling 9
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB019145.1. On Feb 21, 2013 this sequence version replaced NM_019224.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB019145.1, AF071475.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##

ATGACGATCC GACACCAAGG CCAGCAGTAC AGGCCGAGGA TGGCATTTCT TCAAAAGATT 
GAAGCACTCG TGAAGGACAT GCAGAACCCA GAGACGGGAG TCAGAATGCA GAACCAGAGA 
GTCTTGGTCA CCAGTGTCCC TCATGCCATG ACAGGAGGCG ATGTTCTGCA ATGGATCATC 
CAGCGCCTTT GGATCTCTAA CCTCGAGGCG CAGAACTTGG GTAACTTCAT CGTCAAGTAC 
GGCTACATCT ACCCTTTGCA AGACCCGAAG AATCTCGTCC TCAAACCTGA CAGCAGCCTC 
TATCGATTTC AGACGCCGTA CTTCTGGCCC ACTCAGCAGT GGCCAGCTGA GGACACCGAC 
TATGCCATCT ATCTAGCTAA GCGAAATATC AAGAAGAAGG GGATTTTAGA AGAATATGAA 
AAGGAAAACT ATGATTTCTT GAACAAGAAG ATTAATTACA AGTGGGATTT TGTCATCATG 
CAGGCCAAGG AGCAGTACCG GACTGGAAAG GAGAGGAACA AAGCTGACAG GTATGCGCTG 
GATTGCCAGG AGAAGGCGTA TTGGCTGGTG CACCGAAGCC CTCCTGGAAT GAACAATGTG 
TTAGACTACG GCCTGGACCG CGTGACCAAT CCAAACGAAG TTAAGAAACA AACAGTCACT 
GCTGTCAGAA AGGAGATTAT GTATTACCAG CAGGCCTTAA TGAGGTCCAC AGTGAAGTCT 
TCGGTGTCCC TTGGAGGAAT CGTCAAGTAT AGTGAGCAGT TCTCGTCCAA TGATGCCATC 
ATGTCTGGCT GCCTTCCAAG TAATCCTTGG ATCACAGACG ACACCCAGTT CTGGGATTTA 
AACGCCAAGT TGGTGGAGGT CCCAACCAAG ATGCGGGTGG AGAGATGGGC TTTCAACTTC 
AGCGAACTGA TTCGAGACCC CAAGGGCCGG CAGAGCTTCC AGTACTTTCT CAAGAAGGAA 
TTCAGTGGGG AGAACCTGGG ATTCTGGGAA GCCTGTGAGG ATCTGAAGTA TGGGGATCAG 
TCCAAGGTCA AGGAGAAGGC AGAGGAGATC TACAAGCTGT TCCTGGCACC GGGTGCAAGG 
CGATGGATCA ACATAGACGG CAAAACCATG GACATCACCG TGAAGGGGCT GAGACACCCC 
CACCGCTATG TGTTGGACGC GGCGCAGACC CACATTTACA TGCTCATGAA GAAGGATTCT 
TATGCTCGCT ATTTGAAATC TCCGATCTAT AAAGAAATGC TGGCCAAAGC TATCGAGCCA 
CAGGAAACCA CCAAGAGAAG CTCCACCCTC CCATTTATGA GACGCCACCT ACGCTCCAGC 
CCAAGCCCTG TCATTCTGCG GCAGCTGGAA GAAGAAGAGA GAGCTCGAGA AGCAGCCAAC 
ACCGTGGACA TCACCCAGCC AGGTCAGCAC TTGGCTCCCA GCCCTCACCT GGCCGTGTAC 
ACAGGGACCT GCGTGCCTCC CTCTCCCTCC AGCCCCTTCT CACCATCCTG CCGCTCGCCC 
AGGAAGCCCT TCCCTTCCCC AAGTCGCTTC ATCCGGCGGC CCAGCATTGC CATCTGCCCC 
TCGCCCATCC GAGTGGCCCT GGAGGGTTCT TCAGGGCTGG AGGGCAAGGG GGAAGCCAGC 
TGGTCTGGTG CCAACCCTGG GCCCCCAGTC ACTGAGAGCA TCGAGACCTC TGTAGACCGC 
TCACGACCAC ACAGCCAGCC CAGGGCCCCG CTCAAGGCCC GCGCTGCCCT GTCCCTTGGC 
AGGTTTCTGA GACGGGGCTG TTTGGCATCA CCAGTTTTTG CCAGGCTCTC ACCGAAGTGC 
CCTTCTGTGT CACACGGGAA GGTGCAGCCT CTGGGGGACA TGGGTCAACA GCTGCCCAGG 
CTGAAACCCA AGAAAGTAGC CAACTTTTTC CAGATCAAAA TGGAAATGCC TACGGACAGT 
GGGCCCTGCC TGATGGACTC GGATGACCCC GGAGCAGGAG AGTCTGGCGA CCAGACCACG 
GAAAAGGAAG TCATCTGCCC CTGGGAAAGC CTGGCGGAAG GGAAGGCGGG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062097.1
CDS	124..2157
Translation	MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMQNQRVLVTSVPHAMTGGDVLQWIIQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLVLKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEVPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEERAREAANTVDITQPGQHLAPSPHLAVYTGTCVPPSPSSPFSPSCRSPRKPFPSPSRFIRRPSIAICPSPIRVALEGSSGLEGKGEASWSGANPGPPVTESIETSVDRSRPHSQPRAPLKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMGQQLPRLKPKKVANFFQIKMEMPTDSGPCLMDSDDPGAGESGDQTTEKEVICPWESLAEGKAG

Target ORF information:

RefSeq Version	NM_019224.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus regulator of G-protein signaling 9 (Rgs9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019224.2

ORF Insert Sequence:

ATGACGATCC GACACCAAGG CCAGCAGTAC AGGCCGAGGA TGGCATTTCT TCAAAAGATT 
GAAGCACTCG TGAAGGACAT GCAGAACCCA GAGACGGGAG TCAGAATGCA GAACCAGAGA 
GTCTTGGTCA CCAGTGTCCC TCATGCCATG ACAGGAGGCG ATGTTCTGCA ATGGATCATC 
CAGCGCCTTT GGATCTCTAA CCTCGAGGCG CAGAACTTGG GTAACTTCAT CGTCAAGTAC 
GGCTACATCT ACCCTTTGCA AGACCCGAAG AATCTCGTCC TCAAACCTGA CAGCAGCCTC 
TATCGATTTC AGACGCCGTA CTTCTGGCCC ACTCAGCAGT GGCCAGCTGA GGACACCGAC 
TATGCCATCT ATCTAGCTAA GCGAAATATC AAGAAGAAGG GGATTTTAGA AGAATATGAA 
AAGGAAAACT ATGATTTCTT GAACAAGAAG ATTAATTACA AGTGGGATTT TGTCATCATG 
CAGGCCAAGG AGCAGTACCG GACTGGAAAG GAGAGGAACA AAGCTGACAG GTATGCGCTG 
GATTGCCAGG AGAAGGCGTA TTGGCTGGTG CACCGAAGCC CTCCTGGAAT GAACAATGTG 
TTAGACTACG GCCTGGACCG CGTGACCAAT CCAAACGAAG TTAAGAAACA AACAGTCACT 
GCTGTCAGAA AGGAGATTAT GTATTACCAG CAGGCCTTAA TGAGGTCCAC AGTGAAGTCT 
TCGGTGTCCC TTGGAGGAAT CGTCAAGTAT AGTGAGCAGT TCTCGTCCAA TGATGCCATC 
ATGTCTGGCT GCCTTCCAAG TAATCCTTGG ATCACAGACG ACACCCAGTT CTGGGATTTA 
AACGCCAAGT TGGTGGAGGT CCCAACCAAG ATGCGGGTGG AGAGATGGGC TTTCAACTTC 
AGCGAACTGA TTCGAGACCC CAAGGGCCGG CAGAGCTTCC AGTACTTTCT CAAGAAGGAA 
TTCAGTGGGG AGAACCTGGG ATTCTGGGAA GCCTGTGAGG ATCTGAAGTA TGGGGATCAG 
TCCAAGGTCA AGGAGAAGGC AGAGGAGATC TACAAGCTGT TCCTGGCACC GGGTGCAAGG 
CGATGGATCA ACATAGACGG CAAAACCATG GACATCACCG TGAAGGGGCT GAGACACCCC 
CACCGCTATG TGTTGGACGC GGCGCAGACC CACATTTACA TGCTCATGAA GAAGGATTCT 
TATGCTCGCT ATTTGAAATC TCCGATCTAT AAAGAAATGC TGGCCAAAGC TATCGAGCCA 
CAGGAAACCA CCAAGAGAAG CTCCACCCTC CCATTTATGA GACGCCACCT ACGCTCCAGC 
CCAAGCCCTG TCATTCTGCG GCAGCTGGAA GAAGAAGAGA GAGCTCGAGA AGCAGCCAAC 
ACCGTGGACA TCACCCAGCC AGGTCAGCAC TTGGCTCCCA GCCCTCACCT GGCCGTGTAC 
ACAGGGACCT GCGTGCCTCC CTCTCCCTCC AGCCCCTTCT CACCATCCTG CCGCTCGCCC 
AGGAAGCCCT TCCCTTCCCC AAGTCGCTTC ATCCGGCGGC CCAGCATTGC CATCTGCCCC 
TCGCCCATCC GAGTGGCCCT GGAGGGTTCT TCAGGGCTGG AGGGCAAGGG GGAAGCCAGC 
TGGTCTGGTG CCAACCCTGG GCCCCCAGTC ACTGAGAGCA TCGAGACCTC TGTAGACCGC 
TCACGACCAC ACAGCCAGCC CAGGGCCCCG CTCAAGGCCC GCGCTGCCCT GTCCCTTGGC 
AGGTTTCTGA GACGGGGCTG TTTGGCATCA CCAGTTTTTG CCAGGCTCTC ACCGAAGTGC 
CCTTCTGTGT CACACGGGAA GGTGCAGCCT CTGGGGGACA TGGGTCAACA GCTGCCCAGG 
CTGAAACCCA AGAAAGTAGC CAACTTTTTC CAGATCAAAA TGGAAATGCC TACGGACAGT 
GGGCCCTGCC TGATGGACTC GGATGACCCC GGAGCAGGAG AGTCTGGCGA CCAGACCACG 
GAAAAGGAAG TCATCTGCCC CTGGGAAAGC CTGGCGGAAG GGAAGGCGGG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration.
Neuroscience307253-61(2015 Oct)
Sun H,Calipari ES,Beveridge TJ,Jones SR,Chen R

Light-induced translocation of RGS9-1 and G?5L in mouse rod photoreceptors.
PloS one8(3)e58832(2013)
Tian M,Zallocchi M,Wang W,Chen CK,Palczewski K,Delimont D,Cosgrove D,Peng YW

Photoreceptor signaling: supporting vision across a wide range of light intensities.
The Journal of biological chemistry287(3)1620-6(2012 Jan)
Arshavsky VY,Burns ME

The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model.
Brain research bulletin86(5-6)367-72(2011 Nov)
Yin LL,Geng XC,Zhu XZ

Association between regulator of G protein signaling 9-2 and body weight.
PloS one6(11)e27984(2011)
Waugh JL,Celver J,Sharma M,Dufresne RL,Terzi D,Risch SC,Fairbrother WG,Neve RL,Kane JP,Malloy MJ,Pullinger CR,Gu HF,Tsatsanis C,Hamilton SP,Gold SJ,Zachariou V,Kovoor A

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Rgs9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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