| Gene Symbol | Pkp1 |
| Entrez Gene ID | 304822 |
| Full Name | plakophilin 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Pkp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pkp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa05220 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107181.1 | |
| Accession Version | NM_001107181.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1818bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-27 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | plakophilin-1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473958.2. On or before Oct 4, 2007 this sequence version replaced XM_222666.4, XM_001063502.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGAACCACT CGCCGCTCAA GACCGCGCTG GCCTACGAAT GCTTCCAGGA CCAGGACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001100651.1 |
| CDS | 189..2006 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107181.1 |
1 | ATGAACCACT CGCCGCTCAA GACCGCGCTG GCCTACGAAT GCTTCCAGGA CCAGGACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa35379 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006249884.3 | |
| Accession Version | XM_006249884.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | plakophilin-1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249884.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAACCACT CGCCGCTCAA GACCGCGCTG GCCTACGAAT GCTTCCAGGA CCAGGACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006249946.1 |
| CDS | 281..2467 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006249884.3 |
1 | ATGAACCACT CGCCGCTCAA GACCGCGCTG GCCTACGAAT GCTTCCAGGA CCAGGACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins. |
Plakoglobin is required for effective intermediate filament anchorage to desmosomes. |
Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis. |
Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome. |
