Synm cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Synm
Entrez Gene ID	308709
Full Name	synemin
Synonyms	Dmn
General protein information	Preferred Names synemin Names synemin desmuslin synemin, intermediate filament protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	human homolog is an intermediate filament protein; involved in connecting desmin the extracellular matrix [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001134858.3	NP_001128330.1	synemin
XM_006229337.2	XP_006229399.1	synemin isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SYNM	XP_003314921.1
	SYNM	XP_001108469.2
Homo sapiens (human)	SYNM	NP_663780.2
Bos taurus (cattle)	SYNM	NP_001178382.1
Danio rerio (zebrafish)	synm	XP_005159213.1
Rattus norvegicus (Norway rat)	Synm	NP_001128330.1
Xenopus tropicalis (tropical clawed frog)	synm	XP_002939315.2
Mus musculus (house mouse)	Synm	NP_964001.2
Gallus gallus (chicken)	SYNM	NP_990140.1

Gene Ontology
Bibliography

Related articles in PubMed

Myopathic changes in murine skeletal muscle lacking synemin.
Garc?a-Pelagio KP, Muriel J, O'Neill A, Desmond PF, Lovering RM, Lund L, Bond M, Bloch RJ
American journal of physiology. Cell physiology308(6)C448-62(2015 Mar)

Synemin isoforms differentially organize cell junctions and desmin filaments in neonatal cardiomyocytes.
Lund LM, Kerr JP, Lupinetti J, Zhang Y, Russell MA, Bloch RJ, Bond M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(1)137-48(2012 Jan)

Expression profiles of nestin and synemin in reactive astrocytes and M?ller cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentin.
Luna G, Lewis GP, Banna CD, Skalli O, Fisher SK
Molecular vision162511-23(2010 Nov)

Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin.
Sun N, Critchley DR, Paulin D, Li Z, Robson RM
Experimental cell research314(8)1839-49(2008 May)

Human alpha-synemin interacts directly with vinculin and metavinculin.
Sun N, Critchley DR, Paulin D, Li Z, Robson RM
The Biochemical journal409(3)657-67(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We conclude that beta-synemin mediates the association of desmin intermediate filaments with Z disks, whereas alpha-synemin stabilizes junctional complexes between cardiomyocytes.
Title: Synemin isoforms differentially organize cell junctions and desmin filaments in neonatal cardiomyocytes.

Retinal injury induces an upregulation of a complement of four intermediate filament proteins, including synemin and nestin, in Muller cells.
Title: Expression profiles of nestin and synemin in reactive astrocytes and M?ller cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentin.

The following Synm gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Synm cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03683	NM_001134858.3 Latest version!	Rattus norvegicus synemin (Synm), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$811.30 $1159.00
ORa22880	XM_006229337.2 Latest version!	Rattus norvegicus synemin (Synm), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Synm ( NM_001134858.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128330.1 Rattus norvegicus synemin (Synm), mRNA.

Price & Availability↑

CloneID	ORa03683
Clone ID Related Accession (Same CDS sequence)	NM_001134858.3
Accession Version	NM_001134858.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Rattus norvegicus(Norway rat)
Product	synemin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07004173.1 and AC127946.3. On Sep 4, 2014 this sequence version replaced NM_001134858.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CB616732.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCTGTCCT GGCGGCTGCA GACCAGCTCC GAAAAGGCCG AGCTCCAGGA GCTCAATGCC 
CGGCTTTATG AGTACGTGTG CCGGGTGCGA GAGCTGGAGC GCGAGAACCT GCTGCTGGAG 
GAGGAGCTGC GCAGCCGGCT GAGCCGGGAG GACCGCTGGG CCGAAGATCA AGCGCTCTAC 
GCCGAGGAGG CGCGCAGCTT GCGACAGCAG CTCGACGAAC TGAGCTGGTC CACGGCGCTG 
GCCGAGGGCG AGCGCGACGC GCTGCGGAGG GAACTGCTGG ACCTGCAGCG GGAAGGTTTG 
GAAGCCAGCA CTGCCCGCGG CCGCCTGGAT GCCGAGCTAG AAGCGCAGCG GCGGGAGCTG 
GAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GGAGGCAGAG 
CGACGAGACC TGGATGCGGC CCACGAGCGC CAAGTGCGAG AGCTACGCGC CCGTGCCAGC 
AGCCTCACCA TGCACTTCCG AGCCCGCGCC ACCGGCCCCG CCGCGCCCCC GCCGCGCCTG 
CGGGACGTGC ACGACAGCTA CGCCCTGCTA GTGGCCGAGT CGTGGAGGGA GAGCATGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG CAGGCGCTGC GCCGCGGTCA AGAGAGCCGG 
CTCCAGGCGG AGGACGAGGC GCGGCTGTGC GCGCAGGAGG CGGACGCGCT GCGGAACCAG 
GCGCTGGAGT TGGAGCAGCT GCGTGCGAGG CTGGAGGATG AGCTGCTTCG GATGCGCGAG 
GAGTACGGGA TGCAGGCGGA GGAGCGGCAG AGAGTGATCG ACAGCCTGGA GGATGAGAAG 
GATGCCCTTA CCTTGGCCAT GGCTGACAGG CTGCGGGAGT ACCAGGAGCT CCTACAGGTG 
AAGACGGGCC TCAGCTTGGA GGTAGCTACC TACAGGGCCT TGTTGGAAGG AGAAAGCAAT 
CCGGAGATAT TGATCTGGAC CGAGAACATT GAAAACGTGC CACGAGAGTC CAGAAACACA 
TCCTATCGCT ATACCGACTC AGTATTACAG AGGAAGAATG AGAAGAATCT CTTTCCAAGG 
CGAAAAACAC CTTGGGCAGC TGTAAATCAC AGCTCGACTT TGTATTCCAA CGGGCCAGGG 
CACCTTGACT CACAGACAAC CACAGCTGTT GGAAATGCTG CCCGAAGGGG CTTCCTGACC 
TCCTGCTATT CTTCCTCAGC TACAACCTCA CAGCAGAAGC CCCTGGAGAA AACTGTCAGC 
AGTCAAGCCA GTTTAAGACC AGTCATACCA ACCCATGGCT TTCTAAGAAA CACTGATGCT 
CAAGTGAAAA CATTCTCCCA TGGACCCAAA GCTGAAGGCA TGGGGGACAC CCTCACACGG 
CGGGCCACAG AGTCCGTTAT TACCAGAGAG TCATACAGAG GTCACCAGGG CAACGTGGCG 
GCAGGTGCTG TGAACAGCAC TCAGTCAAAT GAGAGGACTG TCATTCTGGG AAAGAAATTA 
GAAACGCAGG CCACTAAGGA GCAAGAGAGG GACAGGTCAG GGGTGGTCAA ATTAAAGCCA 
GAGGAGAAAA TGTTTGATTC TAAAGAGAAG GCTTCGGAGG AAAGAAACTT GAGGTGGGAA 
GAGCTGACCA AGTTAGATGC AAGAGAGAGG GAAAGCCAGC ATTTAAGGAA CGAGGCCAAA 
GGGAAGGAAA CACTGACGGG GAGAAGTAGA AAAGAAAGAG AAGTGCCCAT CAGTCTAGAA 
GTATCTCGGG GCAGCAAATC AGAGGTGTCC ACAATACACT TGCAGTCATC CGGAAGGAAG 
GATTCTGCCA ACAGTAGGGA AAGAGAGGTA AAGACCAAAG AGACAAAGTT CCACTTGGAC 
GGCAAGGACA CTGCTGGCTC TCTGCAGAGT GACTCTACGA CAGAGACCAT AGCAGAAAAC 
ATCGTCACCA CCATCCTTAA GCAGTTTACC CAGTCTCCAG GTGCTGAAGA GAATGTCAGT 
TCTTTGCCAG ACACAAAGGT CACCTACCTG GACCGGAAAG AGTTTCCTGG TGACAGGAAA 
ACCAAGACGG AAATCGTCAT GGAGTCGAAG CTGACAGAAG ACGTCGATGT TTCTGATGAA 
GCTGGCCTGG ACTACCTTCT AAGCAAGGAT GTCAAGGAAG TAGGACTGAA AGGGAAGTCA 
ACAGAGACAG TGATTGGAGA GATGATCAAC CTCGGTCTAA AAGGAAGGGA GGGGAGAGCC 
AAAGTCGTAA ATGTGGAGAT TGTGGAAGAG CCCATGAGCT ACGTAGGTGG TGGGAAAGTA 
GAGTTTTCTA CCCCCTTCCA GGTGGAAGAA GTCGATGATG TGTCTCCCAG CCCCAAGGGG 
TTCATTGAGG AAGAGGAGGG CGAAGGAGAA ACCCACATGG CATTCTCAAT GCATCAACGT 
CAGAGGACCA ACCAGCCCCA GGTGAACGTC CCTCATGTGG AAGAAGTGAC GGAGGCGGGC 
GACTCGGAGG GGGAGCAGAG TTATTTCGTG TCTACCCCAG ATGAGTACCC TGGGGGACAT 
GACAGAGAAG ATGATGGCTC TGTGTATGGG CAGATCCACA TTGAGGAAGA GTCCACCATC 
CGGTACTCAT GGCAAGACGA GATTGCACAG GGGACTTGGA GAAGGAAAGC GAGAGGTGAC 
ACGGGGGAAG AGAAGCACAT GAAGGTCCTG GAGGTTCCAT CGGCTTCCCT GGGTGGTGCC 
TTTGGATCTG CTCACGTGAA GGAAGAAGCT AGTGGTGAAC TCCACGCTGA ACCCACAATC 
ATTGAGAAAG AGATCAAAAT ACCGCATGAA TTCCACACCT CCATAAAGGG CGTCTTCTCC 
AGTGAGCCTC GGCATCAGTT GGTGGAGGTC ATTGGGCAGC TGGAGGAAAC GTTGCCTGAG 
CGCATGAAGG AAGAGCTGTC TGCCCTGACC AGACAGAGTC AAGGAGAGCC AGGGAGTGTC 
TCAGTGGATG TAAAGAAAGT CCAGAGCTCT GCTGGCGGTT CTGTGACCTT AATGGCTGAG 
GTCAACCTCT CGCAGACTGT AGATGCTGAT CAGTTAGACC TGGAGGAGTT GAGCAGGGAC 
GAAGCTGGGG AAATAGAGAA GGCTGTGGAG TCAGTGGTAA GAGAGAGCTT GACCAAGCGC 
TCCAGCCCAG TGCCTAGAAG CCCAGACAGG GAAGATGGAG AGGAGGCGCC TGCCGGTGGC 
TTTCTCTTCA AGCGCTGGGC CACCAGGGAG CTGTATAGCC CGTCTGGTGA GAAGGATGAT 
ACTGACCGGG TCTTTCACAG CTCGGATCAG CGTGTTACCC AGGGCCCAGT GTCAGCCACC 
GTGGAAGTGA CCAGCCCAAC GGGTTTTGTG CAGTCTCATG TGCTGGAGGA TGTAAGCCAG 
TCTGTAAGGC ACGTTAAACT AGGCCCCACT GAGATGTGGA GGACGGAACA GGTGTCCTAC 
GGAGGACCCA CCTCACCGGT GGTGGAGGTA AGTGAAGACT TCAGCGAGGC AGTCAGCTCC 
GAGGGAGCCA GCCGCTCCGT GAGGCACGTT ACACTGGGTC CCCGTCAAAA CCGAGTGTCC 
ACAGAAGTCA TTTTCCGAGG CTCTGTGCCT ACCGGGCAGG AGACAGGAGA CACAGGAGAG 
CCTGACCCTG CAGCACTGTC TGTGGAAGCT GACATCTCAG GGAGTGGCAG GATGCCCGGC 
TCTCAGCAGG CTCACAATGA AAAGGAAACT CCTTTTCCGG GTCCTATTTC TGGGGCAGCC 
CAGGTTGGTA GTAACTTTTC AACTGAAGGG TCAGTGGGTA CCCAGACTTT TGTTAGGCAT 
CTCCAGTTAG GCTCCAGAGA AGGGTTCAGA GAAGAAATCC AGTTCATAGC TCCCATCCCA 
GACAGGGCAG AGTGGGGAGA AGAGGATTCT GGGTACACCA GAGTGTCTCT AGGGAGGAGC 
ACCTCCATCC AGCACATTGA CATCGTGCCT CAGAGGTACC AGGCTTCCAA GCAGGTGGCC 
CCACAGACAT TGGGATTTAG GGACTCAGAA GGCGTAGTCC TGGTGGAGAG GTCAGCAGGT 
ATGACCCAGG CCACTCACAA TTTCACCTCA GATAGAGAAA TCCTCAAGAA GGAAGAGAAC 
ACATTCCAGA GGGTCATTTC TGGGTCCCCT CCAGACAGTG TGGGCGACAC AGGAGCAGAG 
GTGACAGAAA ACATCAGCAG ATCCTTCAGG CACATTCAAA TAGGTCCTAC AGAGGAGGAC 
CCCTCTGAAT ACATTGTCAC CAGTGGACCC TTGTCTAAAA CATTTGTTCT TGACAGTTCC 
GTGGCATCCC CTGGGCCGGG TGGGGGAGCA GACGGCAGTA GCACACCATG TCACATTGCA 
CTGGGGCCCA AAGAAACTTC ATTTACCTTT CAGATGGGTG TAAGTGACAC GAGAGCCATC 
CGCAGCTGGA CCCGAGACAC AGGGTCAGAA GTGGAAGCTC ACAGTGTGTC TCACCACGGT 
GGCTGGAGAG TTGCTCACAG TAGGGATGAG CAATCAGCCA GCACCAGCTC TCAGGCCTCT 
GCTGGGGATG CACACCAGGC CCGTGGAGAG AAAGGCACGG AGCAGGCTGG ATTTGACAAG 
ACGGTGCAGC TGCAAAGAAT GGTAGACCAA AGGTCTGTGG CTTCAGATGA GAAGAAAGTG 
GCCCTTCTCT ATCTAGACAA TGAGGAGGAA GAGGAGGGCG AGGGATGGTT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128330.1
CDS	228..4901
Translation	MLSWRLQTSSEKAELQELNARLYEYVCRVRELERENLLLEEELRSRLSREDRWAEDQALYAEEARSLRQQLDELSWSTALAEGERDALRRELLDLQREGLEASTARGRLDAELEAQRRELEEALGARAALEALLGRLEAERRDLDAAHERQVRELRARASSLTMHFRARATGPAAPPPRLRDVHDSYALLVAESWRESMQLYEDEVRELEQALRRGQESRLQAEDEARLCAQEADALRNQALELEQLRARLEDELLRMREEYGMQAEERQRVIDSLEDEKDALTLAMADRLREYQELLQVKTGLSLEVATYRALLEGESNPEILIWTENIENVPRESRNTSYRYTDSVLQRKNEKNLFPRRKTPWAAVNHSSTLYSNGPGHLDSQTTTAVGNAARRGFLTSCYSSSATTSQQKPLEKTVSSQASLRPVIPTHGFLRNTDAQVKTFSHGPKAEGMGDTLTRRATESVITRESYRGHQGNVAAGAVNSTQSNERTVILGKKLETQATKEQERDRSGVVKLKPEEKMFDSKEKASEERNLRWEELTKLDARERESQHLRNEAKGKETLTGRSRKEREVPISLEVSRGSKSEVSTIHLQSSGRKDSANSREREVKTKETKFHLDGKDTAGSLQSDSTTETIAENIVTTILKQFTQSPGAEENVSSLPDTKVTYLDRKEFPGDRKTKTEIVMESKLTEDVDVSDEAGLDYLLSKDVKEVGLKGKSTETVIGEMINLGLKGREGRAKVVNVEIVEEPMSYVGGGKVEFSTPFQVEEVDDVSPSPKGFIEEEEGEGETHMAFSMHQRQRTNQPQVNVPHVEEVTEAGDSEGEQSYFVSTPDEYPGGHDREDDGSVYGQIHIEEESTIRYSWQDEIAQGTWRRKARGDTGEEKHMKVLEVPSASLGGAFGSAHVKEEASGELHAEPTIIEKEIKIPHEFHTSIKGVFSSEPRHQLVEVIGQLEETLPERMKEELSALTRQSQGEPGSVSVDVKKVQSSAGGSVTLMAEVNLSQTVDADQLDLEELSRDEAGEIEKAVESVVRESLTKRSSPVPRSPDREDGEEAPAGGFLFKRWATRELYSPSGEKDDTDRVFHSSDQRVTQGPVSATVEVTSPTGFVQSHVLEDVSQSVRHVKLGPTEMWRTEQVSYGGPTSPVVEVSEDFSEAVSSEGASRSVRHVTLGPRQNRVSTEVIFRGSVPTGQETGDTGEPDPAALSVEADISGSGRMPGSQQAHNEKETPFPGPISGAAQVGSNFSTEGSVGTQTFVRHLQLGSREGFREEIQFIAPIPDRAEWGEEDSGYTRVSLGRSTSIQHIDIVPQRYQASKQVAPQTLGFRDSEGVVLVERSAGMTQATHNFTSDREILKKEENTFQRVISGSPPDSVGDTGAEVTENISRSFRHIQIGPTEEDPSEYIVTSGPLSKTFVLDSSVASPGPGGGADGSSTPCHIALGPKETSFTFQMGVSDTRAIRSWTRDTGSEVEAHSVSHHGGWRVAHSRDEQSASTSSQASAGDAHQARGEKGTEQAGFDKTVQLQRMVDQRSVASDEKKVALLYLDNEEEEEGEGWF

Target ORF information:

RefSeq Version	NM_001134858.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synemin (Synm), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134858.3

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACCAGCTCC GAAAAGGCCG AGCTCCAGGA GCTCAATGCC 
CGGCTTTATG AGTACGTGTG CCGGGTGCGA GAGCTGGAGC GCGAGAACCT GCTGCTGGAG 
GAGGAGCTGC GCAGCCGGCT GAGCCGGGAG GACCGCTGGG CCGAAGATCA AGCGCTCTAC 
GCCGAGGAGG CGCGCAGCTT GCGACAGCAG CTCGACGAAC TGAGCTGGTC CACGGCGCTG 
GCCGAGGGCG AGCGCGACGC GCTGCGGAGG GAACTGCTGG ACCTGCAGCG GGAAGGTTTG 
GAAGCCAGCA CTGCCCGCGG CCGCCTGGAT GCCGAGCTAG AAGCGCAGCG GCGGGAGCTG 
GAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GGAGGCAGAG 
CGACGAGACC TGGATGCGGC CCACGAGCGC CAAGTGCGAG AGCTACGCGC CCGTGCCAGC 
AGCCTCACCA TGCACTTCCG AGCCCGCGCC ACCGGCCCCG CCGCGCCCCC GCCGCGCCTG 
CGGGACGTGC ACGACAGCTA CGCCCTGCTA GTGGCCGAGT CGTGGAGGGA GAGCATGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG CAGGCGCTGC GCCGCGGTCA AGAGAGCCGG 
CTCCAGGCGG AGGACGAGGC GCGGCTGTGC GCGCAGGAGG CGGACGCGCT GCGGAACCAG 
GCGCTGGAGT TGGAGCAGCT GCGTGCGAGG CTGGAGGATG AGCTGCTTCG GATGCGCGAG 
GAGTACGGGA TGCAGGCGGA GGAGCGGCAG AGAGTGATCG ACAGCCTGGA GGATGAGAAG 
GATGCCCTTA CCTTGGCCAT GGCTGACAGG CTGCGGGAGT ACCAGGAGCT CCTACAGGTG 
AAGACGGGCC TCAGCTTGGA GGTAGCTACC TACAGGGCCT TGTTGGAAGG AGAAAGCAAT 
CCGGAGATAT TGATCTGGAC CGAGAACATT GAAAACGTGC CACGAGAGTC CAGAAACACA 
TCCTATCGCT ATACCGACTC AGTATTACAG AGGAAGAATG AGAAGAATCT CTTTCCAAGG 
CGAAAAACAC CTTGGGCAGC TGTAAATCAC AGCTCGACTT TGTATTCCAA CGGGCCAGGG 
CACCTTGACT CACAGACAAC CACAGCTGTT GGAAATGCTG CCCGAAGGGG CTTCCTGACC 
TCCTGCTATT CTTCCTCAGC TACAACCTCA CAGCAGAAGC CCCTGGAGAA AACTGTCAGC 
AGTCAAGCCA GTTTAAGACC AGTCATACCA ACCCATGGCT TTCTAAGAAA CACTGATGCT 
CAAGTGAAAA CATTCTCCCA TGGACCCAAA GCTGAAGGCA TGGGGGACAC CCTCACACGG 
CGGGCCACAG AGTCCGTTAT TACCAGAGAG TCATACAGAG GTCACCAGGG CAACGTGGCG 
GCAGGTGCTG TGAACAGCAC TCAGTCAAAT GAGAGGACTG TCATTCTGGG AAAGAAATTA 
GAAACGCAGG CCACTAAGGA GCAAGAGAGG GACAGGTCAG GGGTGGTCAA ATTAAAGCCA 
GAGGAGAAAA TGTTTGATTC TAAAGAGAAG GCTTCGGAGG AAAGAAACTT GAGGTGGGAA 
GAGCTGACCA AGTTAGATGC AAGAGAGAGG GAAAGCCAGC ATTTAAGGAA CGAGGCCAAA 
GGGAAGGAAA CACTGACGGG GAGAAGTAGA AAAGAAAGAG AAGTGCCCAT CAGTCTAGAA 
GTATCTCGGG GCAGCAAATC AGAGGTGTCC ACAATACACT TGCAGTCATC CGGAAGGAAG 
GATTCTGCCA ACAGTAGGGA AAGAGAGGTA AAGACCAAAG AGACAAAGTT CCACTTGGAC 
GGCAAGGACA CTGCTGGCTC TCTGCAGAGT GACTCTACGA CAGAGACCAT AGCAGAAAAC 
ATCGTCACCA CCATCCTTAA GCAGTTTACC CAGTCTCCAG GTGCTGAAGA GAATGTCAGT 
TCTTTGCCAG ACACAAAGGT CACCTACCTG GACCGGAAAG AGTTTCCTGG TGACAGGAAA 
ACCAAGACGG AAATCGTCAT GGAGTCGAAG CTGACAGAAG ACGTCGATGT TTCTGATGAA 
GCTGGCCTGG ACTACCTTCT AAGCAAGGAT GTCAAGGAAG TAGGACTGAA AGGGAAGTCA 
ACAGAGACAG TGATTGGAGA GATGATCAAC CTCGGTCTAA AAGGAAGGGA GGGGAGAGCC 
AAAGTCGTAA ATGTGGAGAT TGTGGAAGAG CCCATGAGCT ACGTAGGTGG TGGGAAAGTA 
GAGTTTTCTA CCCCCTTCCA GGTGGAAGAA GTCGATGATG TGTCTCCCAG CCCCAAGGGG 
TTCATTGAGG AAGAGGAGGG CGAAGGAGAA ACCCACATGG CATTCTCAAT GCATCAACGT 
CAGAGGACCA ACCAGCCCCA GGTGAACGTC CCTCATGTGG AAGAAGTGAC GGAGGCGGGC 
GACTCGGAGG GGGAGCAGAG TTATTTCGTG TCTACCCCAG ATGAGTACCC TGGGGGACAT 
GACAGAGAAG ATGATGGCTC TGTGTATGGG CAGATCCACA TTGAGGAAGA GTCCACCATC 
CGGTACTCAT GGCAAGACGA GATTGCACAG GGGACTTGGA GAAGGAAAGC GAGAGGTGAC 
ACGGGGGAAG AGAAGCACAT GAAGGTCCTG GAGGTTCCAT CGGCTTCCCT GGGTGGTGCC 
TTTGGATCTG CTCACGTGAA GGAAGAAGCT AGTGGTGAAC TCCACGCTGA ACCCACAATC 
ATTGAGAAAG AGATCAAAAT ACCGCATGAA TTCCACACCT CCATAAAGGG CGTCTTCTCC 
AGTGAGCCTC GGCATCAGTT GGTGGAGGTC ATTGGGCAGC TGGAGGAAAC GTTGCCTGAG 
CGCATGAAGG AAGAGCTGTC TGCCCTGACC AGACAGAGTC AAGGAGAGCC AGGGAGTGTC 
TCAGTGGATG TAAAGAAAGT CCAGAGCTCT GCTGGCGGTT CTGTGACCTT AATGGCTGAG 
GTCAACCTCT CGCAGACTGT AGATGCTGAT CAGTTAGACC TGGAGGAGTT GAGCAGGGAC 
GAAGCTGGGG AAATAGAGAA GGCTGTGGAG TCAGTGGTAA GAGAGAGCTT GACCAAGCGC 
TCCAGCCCAG TGCCTAGAAG CCCAGACAGG GAAGATGGAG AGGAGGCGCC TGCCGGTGGC 
TTTCTCTTCA AGCGCTGGGC CACCAGGGAG CTGTATAGCC CGTCTGGTGA GAAGGATGAT 
ACTGACCGGG TCTTTCACAG CTCGGATCAG CGTGTTACCC AGGGCCCAGT GTCAGCCACC 
GTGGAAGTGA CCAGCCCAAC GGGTTTTGTG CAGTCTCATG TGCTGGAGGA TGTAAGCCAG 
TCTGTAAGGC ACGTTAAACT AGGCCCCACT GAGATGTGGA GGACGGAACA GGTGTCCTAC 
GGAGGACCCA CCTCACCGGT GGTGGAGGTA AGTGAAGACT TCAGCGAGGC AGTCAGCTCC 
GAGGGAGCCA GCCGCTCCGT GAGGCACGTT ACACTGGGTC CCCGTCAAAA CCGAGTGTCC 
ACAGAAGTCA TTTTCCGAGG CTCTGTGCCT ACCGGGCAGG AGACAGGAGA CACAGGAGAG 
CCTGACCCTG CAGCACTGTC TGTGGAAGCT GACATCTCAG GGAGTGGCAG GATGCCCGGC 
TCTCAGCAGG CTCACAATGA AAAGGAAACT CCTTTTCCGG GTCCTATTTC TGGGGCAGCC 
CAGGTTGGTA GTAACTTTTC AACTGAAGGG TCAGTGGGTA CCCAGACTTT TGTTAGGCAT 
CTCCAGTTAG GCTCCAGAGA AGGGTTCAGA GAAGAAATCC AGTTCATAGC TCCCATCCCA 
GACAGGGCAG AGTGGGGAGA AGAGGATTCT GGGTACACCA GAGTGTCTCT AGGGAGGAGC 
ACCTCCATCC AGCACATTGA CATCGTGCCT CAGAGGTACC AGGCTTCCAA GCAGGTGGCC 
CCACAGACAT TGGGATTTAG GGACTCAGAA GGCGTAGTCC TGGTGGAGAG GTCAGCAGGT 
ATGACCCAGG CCACTCACAA TTTCACCTCA GATAGAGAAA TCCTCAAGAA GGAAGAGAAC 
ACATTCCAGA GGGTCATTTC TGGGTCCCCT CCAGACAGTG TGGGCGACAC AGGAGCAGAG 
GTGACAGAAA ACATCAGCAG ATCCTTCAGG CACATTCAAA TAGGTCCTAC AGAGGAGGAC 
CCCTCTGAAT ACATTGTCAC CAGTGGACCC TTGTCTAAAA CATTTGTTCT TGACAGTTCC 
GTGGCATCCC CTGGGCCGGG TGGGGGAGCA GACGGCAGTA GCACACCATG TCACATTGCA 
CTGGGGCCCA AAGAAACTTC ATTTACCTTT CAGATGGGTG TAAGTGACAC GAGAGCCATC 
CGCAGCTGGA CCCGAGACAC AGGGTCAGAA GTGGAAGCTC ACAGTGTGTC TCACCACGGT 
GGCTGGAGAG TTGCTCACAG TAGGGATGAG CAATCAGCCA GCACCAGCTC TCAGGCCTCT 
GCTGGGGATG CACACCAGGC CCGTGGAGAG AAAGGCACGG AGCAGGCTGG ATTTGACAAG 
ACGGTGCAGC TGCAAAGAAT GGTAGACCAA AGGTCTGTGG CTTCAGATGA GAAGAAAGTG 
GCCCTTCTCT ATCTAGACAA TGAGGAGGAA GAGGAGGGCG AGGGATGGTT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Synm ( XM_006229337.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229399.1 Rattus norvegicus synemin (Synm), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22880
Clone ID Related Accession (Same CDS sequence)	XM_006229337.2
Accession Version	XM_006229337.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	synemin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006229337.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCT GGCGGCTGCA GACCAGCTCC GAAAAGGCCG AGCTCCAGGA GCTCAATGCC 
CGGCTTTATG AGTACGTGTG CCGGGTGCGA GAGCTGGAGC GCGAGAACCT GCTGCTGGAG 
GAGGAGCTGC GCAGCCGGCT GAGCCGGGAG GACCGCTGGG CCGAAGATCA AGCGCTCTAC 
GCCGAGGAGG CGCGCAGCTT GCGACAGCAG CTCGACGAAC TGAGCTGGTC CACGGCGCTG 
GCCGAGGGCG AGCGCGACGC GCTGCGGAGG GAACTGCTGG ACCTGCAGCG GGAAGGTTTG 
GAAGCCAGCA CTGCCCGCGG CCGCCTGGAT GCCGAGCTAG AAGCGCAGCG GCGGGAGCTG 
GAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GGAGGCAGAG 
CGACGAGACC TGGATGCGGC CCACGAGCGC CAAGTGCGAG AGCTACGCGC CCGTGCCAGC 
AGCCTCACCA TGCACTTCCG AGCCCGCGCC ACCGGCCCCG CCGCGCCCCC GCCGCGCCTG 
CGGGACGTGC ACGACAGCTA CGCCCTGCTA GTGGCCGAGT CGTGGAGGGA GAGCATGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG CAGGCGCTGC GCCGCGGTCA AGAGAGCCGG 
CTCCAGGCGG AGGACGAGGC GCGGCTGTGC GCGCAGGAGG CGGACGCGCT GCGGAACCAG 
GCGCTGGAGT TGGAGCAGCT GCGTGCGAGG CTGGAGGATG AGCTGCTTCG GATGCGCGAG 
GAGTACGGGA TGCAGGCGGA GGAGCGGCAG AGAGTGATCG ACAGCCTGGA GGATGAGAAG 
GATGCCCTTA CCTTGGCCAT GGCTGACAGG CTGCGGGAGT ACCAGGAGCT CCTACAGGTG 
AAGACGGGCC TCAGCTTGGA GGTAGCTACC TACAGGGCCT TGTTGGAAGG AGAAAGCAAT 
CCGGAGATAT TGATCTGGAC CGAGAACATT GAAAACGTGC CACGAGAGTC CAGAAACACA 
TCCTATCGCT ATACCGACTC AGTATTACAG AGGAAGAATG AGAAGAATCT CTTTCCAAGG 
CGAAAAACAC CTTGGGCAGC TGTAAATCAC AGCTCGACTT TGTATTCCAA CGGGCCAGGG 
CACCTTGACT CACAGACAAC CACAGCTGTT GGAAATGCTG CCCGAAGGGG CTTCCTGACC 
TCCTGCTATT CTTCCTCAGC TACAACCTCA CAGCAGAAGC CCCTGGAGAA AACTGTCAGC 
AGTCAAGCCA GTTTAAGACC AGTCATACCA ACCCATGGCT TTCTAAGAAA CACTGATGCT 
CAAGTGAAAA CATTCTCCCA TGGACCCAAA GCTGAAGGCA TGGGGGACAC CCTCACACGG 
CGGGCCACAG AGTCCGTTAT TACCAGAGAG TCATACAGAG GTCACCAGGG CAACGTGGCG 
GCAGGTGCTG TGAACAGCAC TCAGTCAAAT GAGAGGACTG TCATTCTGGG AAAGAAATTA 
GAAACGCAGG CCACTAAGGA GCAAGAGAGG GACAGGTCAG GGGTGGTCAA ATTAAAGCCA 
GAGGAGAAAA TGTTTGATTC TAAAGAGAAG GCTTCGGAGG AAAGAAACTT GAGGTGGGAA 
GAGCTGACCA AGTTAGATGC AAGAGAGAGG GAAAGCCAGC ATTTAAGGAA CGAGGCCAAA 
GGGAAGGAAA CACTGACGGG GAGAAGTAGA AAAGAAAGAG AAGTGCCCAT CAGTCTAGAA 
GTATCTCGGG GCAGCAAATC AGAGGTGTCC ACAATACACT TGCAGTCATC CGGAAGGAAG 
GATTCTGCCA ACAGTAGGGA AAGAGAGGTA AAGACCAAAG AGACAAAGTT CCACTTGGAC 
GGCAAGGACA CTGCTGGCTC TCTGCAGAGT GACTCTACGA CAGAGACCAT AGCAGAAAAC 
ATCGTCACCA CCATCCTTAA GCAGTTTACC CAGTCTCCAG GTGCTGAAGA GAATGTCAGT 
TCTTTGCCAG ACACAAAGGT CACCTACCTG GACCGGAAAG AGTTTCCTGG TGACAGGAAA 
ACCAAGACGG AAATCGTCAT GGAGTCGAAG CTGACAGAAG ACGTCGATGT TTCTGATGAA 
GCTGGCCTGG ACTACCTTCT AAGCAAGGAT GTCAAGGAAG TAGGACTGAA AGGGAAGTCA 
ACAGAGACAG TGATTGGAGA GATGATCAAC CTCGGTCTAA AAGGAAGGGA GGGGAGAGCC 
AAAGTCGTAA ATGTGGAGAT TGTGGAAGAG CCCATGAGCT ACGTAGGTGG TGGGAAAGTA 
GAGTTTTCTA CCCCCTTCCA GGTGGAAGAA GTCGATGATG TGTCTCCCAG CCCCAAGGGG 
TTCATTGAGG AAGAGGAGGG CGAAGGAGAA ACCCACATGG CATTCTCAAT GCATCAACGT 
CAGAGGACCA ACCAGCCCCA GGTGAACGTC CCTCATGTGG AAGAAGTGAC GGAGGCGGGC 
GACTCGGAGG GGGAGCAGAG TTATTTCGTG TCTACCCCAG ATGAGTACCC TGGGGGACAT 
GACAGAGAAG ATGATGGCTC TGTGTATGGG CAGATCCACA TTGAGGAAGA GTCCACCATC 
CGGTACTCAT GGCAAGACGA GATTGCACAG GGGACTTGGA GAAGGAAAGC GAGAGGTGAC 
ACGGGGGAAG AGAAGCACAT GAAGGTCCTG GAGGTTCCAT CGGCTTCCCT GGGTGGTGCC 
TTTGGATCTG CTCACGTGAA GGAAGAAGCT AGTGGTGAAC TCCACGCTGA ACCCACAATC 
ATTGAGAAAG AGATCAAAAT ACCGCATGAA TTCCACACCT CCATAAAGGG CGTCTTCTCC 
AGTGAGCCTC GGCATCAGTT GGTGGAGGTC ATTGGGCAGC TGGAGGAAAC GTTGCCTGAG 
CGCATGAAGG AAGAGCTGTC TGCCCTGACC AGACAGAGTC AAGGAGAGCC AGGGAGTGTC 
TCAGTGGATG TAAAGAAAGT CCAGAGCTCT GCTGGCGGTT CTGTGACCTT AATGGCTGAG 
GTCAACCTCT CGCAGACTGT AGATGCTGAT CAGTTAGACC TGGAGGAGTT GAGCAGGGAC 
GAAGCTGGGG AAATAGAGAA GGCTGTGGAG TCAGTGGTAA GAGAGAGCTT GACCAAGCGC 
TCCAGCCCAG TGCCTAGAAG CCCAGACAGG GAAGATGGAG AGGAGGCGCC TGCCGGTGGC 
TTTCTCTTCA AGCGCTGGGC CACCAGGGAG CTGTATAGCC CGTCTGGTGA GAAGGATGAT 
ACTGACCGGG TCTTTCACAG CTCGGATCAG CGTGTTACCC AGGGCCCAGT GTCAGCCACC 
GTGGAAGTGA CCAGCCCAAC GGGTTTTGTG CAGTCTCATG TGCTGGAGGA TGTAAGCCAG 
TCTGTAAGGC ACGTTAAACT AGGCCCCACT GAGATGTGGA GGACGGAACA GGTGTCCTAC 
GGAGGACCCA CCTCACCGGT GGTGGAGATG GGTGTAAGTG ACACGAGAGC CATCCGCAGC 
TGGACCCGAG ACACAGGGTC AGAAGTGGAA GCTCACAGTG TGTCTCACCA CGGTGGCTGG 
AGAGTTGCTC ACAGTAGGGA TGAGCAATCA GCCAGCACCA GCTCTCAGGC CTCTGCTGGG 
GATGCACACC AGGCCCGTGG AGAGAAAGGC ACGGAGCAGG CTGGATTTGA CAAGACGGTG 
CAGCTGCAAA GAATGGTAGA CCAAAGGTCT GTGGCTTCAG ATGAGAAGAA AGTGGCCCTT 
CTCTATCTAG ACAATGAGGA GGAAGAGGAG GGCGAGGGAT GGTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229399.1
CDS	223..3990
Translation	MLSWRLQTSSEKAELQELNARLYEYVCRVRELERENLLLEEELRSRLSREDRWAEDQALYAEEARSLRQQLDELSWSTALAEGERDALRRELLDLQREGLEASTARGRLDAELEAQRRELEEALGARAALEALLGRLEAERRDLDAAHERQVRELRARASSLTMHFRARATGPAAPPPRLRDVHDSYALLVAESWRESMQLYEDEVRELEQALRRGQESRLQAEDEARLCAQEADALRNQALELEQLRARLEDELLRMREEYGMQAEERQRVIDSLEDEKDALTLAMADRLREYQELLQVKTGLSLEVATYRALLEGESNPEILIWTENIENVPRESRNTSYRYTDSVLQRKNEKNLFPRRKTPWAAVNHSSTLYSNGPGHLDSQTTTAVGNAARRGFLTSCYSSSATTSQQKPLEKTVSSQASLRPVIPTHGFLRNTDAQVKTFSHGPKAEGMGDTLTRRATESVITRESYRGHQGNVAAGAVNSTQSNERTVILGKKLETQATKEQERDRSGVVKLKPEEKMFDSKEKASEERNLRWEELTKLDARERESQHLRNEAKGKETLTGRSRKEREVPISLEVSRGSKSEVSTIHLQSSGRKDSANSREREVKTKETKFHLDGKDTAGSLQSDSTTETIAENIVTTILKQFTQSPGAEENVSSLPDTKVTYLDRKEFPGDRKTKTEIVMESKLTEDVDVSDEAGLDYLLSKDVKEVGLKGKSTETVIGEMINLGLKGREGRAKVVNVEIVEEPMSYVGGGKVEFSTPFQVEEVDDVSPSPKGFIEEEEGEGETHMAFSMHQRQRTNQPQVNVPHVEEVTEAGDSEGEQSYFVSTPDEYPGGHDREDDGSVYGQIHIEEESTIRYSWQDEIAQGTWRRKARGDTGEEKHMKVLEVPSASLGGAFGSAHVKEEASGELHAEPTIIEKEIKIPHEFHTSIKGVFSSEPRHQLVEVIGQLEETLPERMKEELSALTRQSQGEPGSVSVDVKKVQSSAGGSVTLMAEVNLSQTVDADQLDLEELSRDEAGEIEKAVESVVRESLTKRSSPVPRSPDREDGEEAPAGGFLFKRWATRELYSPSGEKDDTDRVFHSSDQRVTQGPVSATVEVTSPTGFVQSHVLEDVSQSVRHVKLGPTEMWRTEQVSYGGPTSPVVEMGVSDTRAIRSWTRDTGSEVEAHSVSHHGGWRVAHSRDEQSASTSSQASAGDAHQARGEKGTEQAGFDKTVQLQRMVDQRSVASDEKKVALLYLDNEEEEEGEGWF

Target ORF information:

RefSeq Version	XM_006229337.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synemin (Synm), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229337.2

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACCAGCTCC GAAAAGGCCG AGCTCCAGGA GCTCAATGCC 
CGGCTTTATG AGTACGTGTG CCGGGTGCGA GAGCTGGAGC GCGAGAACCT GCTGCTGGAG 
GAGGAGCTGC GCAGCCGGCT GAGCCGGGAG GACCGCTGGG CCGAAGATCA AGCGCTCTAC 
GCCGAGGAGG CGCGCAGCTT GCGACAGCAG CTCGACGAAC TGAGCTGGTC CACGGCGCTG 
GCCGAGGGCG AGCGCGACGC GCTGCGGAGG GAACTGCTGG ACCTGCAGCG GGAAGGTTTG 
GAAGCCAGCA CTGCCCGCGG CCGCCTGGAT GCCGAGCTAG AAGCGCAGCG GCGGGAGCTG 
GAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GGAGGCAGAG 
CGACGAGACC TGGATGCGGC CCACGAGCGC CAAGTGCGAG AGCTACGCGC CCGTGCCAGC 
AGCCTCACCA TGCACTTCCG AGCCCGCGCC ACCGGCCCCG CCGCGCCCCC GCCGCGCCTG 
CGGGACGTGC ACGACAGCTA CGCCCTGCTA GTGGCCGAGT CGTGGAGGGA GAGCATGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG CAGGCGCTGC GCCGCGGTCA AGAGAGCCGG 
CTCCAGGCGG AGGACGAGGC GCGGCTGTGC GCGCAGGAGG CGGACGCGCT GCGGAACCAG 
GCGCTGGAGT TGGAGCAGCT GCGTGCGAGG CTGGAGGATG AGCTGCTTCG GATGCGCGAG 
GAGTACGGGA TGCAGGCGGA GGAGCGGCAG AGAGTGATCG ACAGCCTGGA GGATGAGAAG 
GATGCCCTTA CCTTGGCCAT GGCTGACAGG CTGCGGGAGT ACCAGGAGCT CCTACAGGTG 
AAGACGGGCC TCAGCTTGGA GGTAGCTACC TACAGGGCCT TGTTGGAAGG AGAAAGCAAT 
CCGGAGATAT TGATCTGGAC CGAGAACATT GAAAACGTGC CACGAGAGTC CAGAAACACA 
TCCTATCGCT ATACCGACTC AGTATTACAG AGGAAGAATG AGAAGAATCT CTTTCCAAGG 
CGAAAAACAC CTTGGGCAGC TGTAAATCAC AGCTCGACTT TGTATTCCAA CGGGCCAGGG 
CACCTTGACT CACAGACAAC CACAGCTGTT GGAAATGCTG CCCGAAGGGG CTTCCTGACC 
TCCTGCTATT CTTCCTCAGC TACAACCTCA CAGCAGAAGC CCCTGGAGAA AACTGTCAGC 
AGTCAAGCCA GTTTAAGACC AGTCATACCA ACCCATGGCT TTCTAAGAAA CACTGATGCT 
CAAGTGAAAA CATTCTCCCA TGGACCCAAA GCTGAAGGCA TGGGGGACAC CCTCACACGG 
CGGGCCACAG AGTCCGTTAT TACCAGAGAG TCATACAGAG GTCACCAGGG CAACGTGGCG 
GCAGGTGCTG TGAACAGCAC TCAGTCAAAT GAGAGGACTG TCATTCTGGG AAAGAAATTA 
GAAACGCAGG CCACTAAGGA GCAAGAGAGG GACAGGTCAG GGGTGGTCAA ATTAAAGCCA 
GAGGAGAAAA TGTTTGATTC TAAAGAGAAG GCTTCGGAGG AAAGAAACTT GAGGTGGGAA 
GAGCTGACCA AGTTAGATGC AAGAGAGAGG GAAAGCCAGC ATTTAAGGAA CGAGGCCAAA 
GGGAAGGAAA CACTGACGGG GAGAAGTAGA AAAGAAAGAG AAGTGCCCAT CAGTCTAGAA 
GTATCTCGGG GCAGCAAATC AGAGGTGTCC ACAATACACT TGCAGTCATC CGGAAGGAAG 
GATTCTGCCA ACAGTAGGGA AAGAGAGGTA AAGACCAAAG AGACAAAGTT CCACTTGGAC 
GGCAAGGACA CTGCTGGCTC TCTGCAGAGT GACTCTACGA CAGAGACCAT AGCAGAAAAC 
ATCGTCACCA CCATCCTTAA GCAGTTTACC CAGTCTCCAG GTGCTGAAGA GAATGTCAGT 
TCTTTGCCAG ACACAAAGGT CACCTACCTG GACCGGAAAG AGTTTCCTGG TGACAGGAAA 
ACCAAGACGG AAATCGTCAT GGAGTCGAAG CTGACAGAAG ACGTCGATGT TTCTGATGAA 
GCTGGCCTGG ACTACCTTCT AAGCAAGGAT GTCAAGGAAG TAGGACTGAA AGGGAAGTCA 
ACAGAGACAG TGATTGGAGA GATGATCAAC CTCGGTCTAA AAGGAAGGGA GGGGAGAGCC 
AAAGTCGTAA ATGTGGAGAT TGTGGAAGAG CCCATGAGCT ACGTAGGTGG TGGGAAAGTA 
GAGTTTTCTA CCCCCTTCCA GGTGGAAGAA GTCGATGATG TGTCTCCCAG CCCCAAGGGG 
TTCATTGAGG AAGAGGAGGG CGAAGGAGAA ACCCACATGG CATTCTCAAT GCATCAACGT 
CAGAGGACCA ACCAGCCCCA GGTGAACGTC CCTCATGTGG AAGAAGTGAC GGAGGCGGGC 
GACTCGGAGG GGGAGCAGAG TTATTTCGTG TCTACCCCAG ATGAGTACCC TGGGGGACAT 
GACAGAGAAG ATGATGGCTC TGTGTATGGG CAGATCCACA TTGAGGAAGA GTCCACCATC 
CGGTACTCAT GGCAAGACGA GATTGCACAG GGGACTTGGA GAAGGAAAGC GAGAGGTGAC 
ACGGGGGAAG AGAAGCACAT GAAGGTCCTG GAGGTTCCAT CGGCTTCCCT GGGTGGTGCC 
TTTGGATCTG CTCACGTGAA GGAAGAAGCT AGTGGTGAAC TCCACGCTGA ACCCACAATC 
ATTGAGAAAG AGATCAAAAT ACCGCATGAA TTCCACACCT CCATAAAGGG CGTCTTCTCC 
AGTGAGCCTC GGCATCAGTT GGTGGAGGTC ATTGGGCAGC TGGAGGAAAC GTTGCCTGAG 
CGCATGAAGG AAGAGCTGTC TGCCCTGACC AGACAGAGTC AAGGAGAGCC AGGGAGTGTC 
TCAGTGGATG TAAAGAAAGT CCAGAGCTCT GCTGGCGGTT CTGTGACCTT AATGGCTGAG 
GTCAACCTCT CGCAGACTGT AGATGCTGAT CAGTTAGACC TGGAGGAGTT GAGCAGGGAC 
GAAGCTGGGG AAATAGAGAA GGCTGTGGAG TCAGTGGTAA GAGAGAGCTT GACCAAGCGC 
TCCAGCCCAG TGCCTAGAAG CCCAGACAGG GAAGATGGAG AGGAGGCGCC TGCCGGTGGC 
TTTCTCTTCA AGCGCTGGGC CACCAGGGAG CTGTATAGCC CGTCTGGTGA GAAGGATGAT 
ACTGACCGGG TCTTTCACAG CTCGGATCAG CGTGTTACCC AGGGCCCAGT GTCAGCCACC 
GTGGAAGTGA CCAGCCCAAC GGGTTTTGTG CAGTCTCATG TGCTGGAGGA TGTAAGCCAG 
TCTGTAAGGC ACGTTAAACT AGGCCCCACT GAGATGTGGA GGACGGAACA GGTGTCCTAC 
GGAGGACCCA CCTCACCGGT GGTGGAGATG GGTGTAAGTG ACACGAGAGC CATCCGCAGC 
TGGACCCGAG ACACAGGGTC AGAAGTGGAA GCTCACAGTG TGTCTCACCA CGGTGGCTGG 
AGAGTTGCTC ACAGTAGGGA TGAGCAATCA GCCAGCACCA GCTCTCAGGC CTCTGCTGGG 
GATGCACACC AGGCCCGTGG AGAGAAAGGC ACGGAGCAGG CTGGATTTGA CAAGACGGTG 
CAGCTGCAAA GAATGGTAGA CCAAAGGTCT GTGGCTTCAG ATGAGAAGAA AGTGGCCCTT 
CTCTATCTAG ACAATGAGGA GGAAGAGGAG GGCGAGGGAT GGTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Myopathic changes in murine skeletal muscle lacking synemin.
American journal of physiology. Cell physiology308(6)C448-62(2015 Mar)
Garc?a-Pelagio KP,Muriel J,O'Neill A,Desmond PF,Lovering RM,Lund L,Bond M,Bloch RJ

Synemin isoforms differentially organize cell junctions and desmin filaments in neonatal cardiomyocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(1)137-48(2012 Jan)
Lund LM,Kerr JP,Lupinetti J,Zhang Y,Russell MA,Bloch RJ,Bond M

Expression profiles of nestin and synemin in reactive astrocytes and M?ller cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentin.
Molecular vision162511-23(2010 Nov)
Luna G,Lewis GP,Banna CD,Skalli O,Fisher SK

Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin.
Experimental cell research314(8)1839-49(2008 May)
Sun N,Critchley DR,Paulin D,Li Z,Robson RM

Human alpha-synemin interacts directly with vinculin and metavinculin.
The Biochemical journal409(3)657-67(2008 Feb)
Sun N,Critchley DR,Paulin D,Li Z,Robson RM