| Gene Symbol | Fam83b |
| Entrez Gene ID | 315829 |
| Full Name | family with sequence similarity 83, member B |
| Synonyms | RGD1311988 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Fam83b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fam83b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa06807 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001108169.1 | |
| Accession Version | NM_001108169.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3027bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protein FAM83B | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473954.2. On or before Oct 4, 2007 this sequence version replaced XM_236420.4, XM_001058463.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGAGACTT CATCAATGCT TTCCTCACTA AATGATGAGT GCAGGTCTGA CAACTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001101639.1 |
| CDS | 116..3142 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001108169.1 |
1 | ATGGAGACTT CATCAATGCT TTCCTCACTA AATGATGAGT GCAGGTCTGA CAACTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B. |
FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. |
FAM83B mediates EGFR- and RAS-driven oncogenic transformation. |
