Gene Symbol | Jagn1 |
Entrez Gene ID | 502872 |
Full Name | jagunal homolog 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Jagn1 cDNA ORF clone
Gene Symbol | Jagn1 |
Entrez Gene ID | 502872 |
Full Name | jagunal homolog 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006237053.3 | XP_006237115.1 | protein jagunal homolog 1 isoform X1 |
NM_001044272.1 | NP_001037737.1 | protein jagunal homolog 1 |
Homo sapiens (human) | JAGN1 | NP_115881.3 |
Pan troglodytes (chimpanzee) | JAGN1 | XP_516267.2 |
Danio rerio (zebrafish) | jagn1a | NP_001005774.1 |
Bos taurus (cattle) | JAGN1 | NP_001039915.1 |
Mus musculus (house mouse) | Jagn1 | NP_080641.1 |
Rattus norvegicus (Norway rat) | Jagn1 | NP_001037737.1 |
JAGN1 | XP_001093581.1 | |
Xenopus tropicalis (tropical clawed frog) | jagn1 | NP_001001898.1 |
Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis.
Nosak C, Silva PN, Sollazzo P, Moon KM, Odisho T, Foster LJ, Rocheleau JV, Volchuk A
PloS one11(2)e0149177(2016)
JAGN1 Deficient Severe Congenital Neutropenia: Two Cases from the Same Family.
Baris S, Karakoc-Aydiner E, Ozen A, Delil K, Kiykim A, Ogulur I, Baris I, Barlan IB
Journal of clinical immunology35(4)339-43(2015 May)
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.
Wirnsberger G, Zwolanek F, Stadlmann J, Tortola L, Liu SW, Perlot T, J?rvinen P, D?rnberger G, Kozieradzki I, Sarao R, De Martino A, Boztug K, Mechtler K, Kuchler K, Klein C, Elling U, Penninger JM
Nature genetics46(9)1028-33(2014 Sep)
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia.
Boztug K, J?rvinen PM, Salzer E, Racek T, M?nch S, Garncarz W, Gertz EM, Sch?ffer AA, Antonopoulos A, Haslam SM, Schieck L, Pucha?ka J, Diestelhorst J, Appaswamy G, Lescoeur B, Giambruno R, Bigenzahn JW, Elling U, Pfeifer D, Conde CD, Albert MH, Welte K, Brandes G, Sherkat R, van der Werff Ten Bosch J, Rezaei N, Etzioni A, Bellann?-Chantelot C, Superti-Furga G, Penninger JM, Bennett KL, von Blume J, Dell A, Donadieu J, Klein C
Nature genetics46(9)1021-7(2014 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results identify a novel role for Jagn1 in regulating proinsulin biosynthesis.
Title: Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis.
The following Jagn1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jagn1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa08324 | |
Clone ID Related Accession (Same CDS sequence) | NM_001044272.1 | |
Accession Version | NM_001044272.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein jagunal homolog 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098749.1. On or before Aug 24, 2006 this sequence version replaced XM_001054553.1, XM_001078768.1. ##Evidence-Data-START## Transcript exon combination :: BC098749.1, FQ225993.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGTCTC GGGCAGGCCC ACGAGCGGCC GGCACCGACG GCAGCGACTT TCAGCACCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001037737.1 |
CDS | 96..647 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001044272.1 |
1 | ATGGCGTCTC GGGCAGGCCC ACGAGCGGCC GGCACCGACG GCAGCGACTT TCAGCACCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa27580 | |
Clone ID Related Accession (Same CDS sequence) | XM_006237053.3 | |
Accession Version | XM_006237053.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 204bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein jagunal homolog 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237053.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGTCTC GGGCAGGCCC ACGAGCGGCC GGCACCGACG GCAGCGACTT TCAGCACCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006237115.1 |
CDS | 141..344 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006237053.3 |
1 | ATGGCGTCTC GGGCAGGCCC ACGAGCGGCC GGCACCGACG GCAGCGACTT TCAGCACCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. |
JAGN1 Deficient Severe Congenital Neutropenia: Two Cases from the Same Family. |
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense. |
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia. |