Gene Symbol | Bbox1 |
Entrez Gene ID | 64564 |
Full Name | gamma-butyrobetaine hydroxylase 1 |
Synonyms | Bbh,Bbox |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Bbox1 cDNA ORF clone
Gene Symbol | Bbox1 |
Entrez Gene ID | 64564 |
Full Name | gamma-butyrobetaine hydroxylase 1 |
Synonyms | Bbh,Bbox |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_022629.1 | NP_072151.1 | gamma-butyrobetaine dioxygenase |
XM_017592026.1 | XP_017447515.1 | gamma-butyrobetaine dioxygenase isoform X1 |
Canis lupus familiaris (dog) | BBOX1 | XP_534096.2 |
Rattus norvegicus (Norway rat) | Bbox1 | NP_072151.1 |
Bos taurus (cattle) | BBOX1 | NP_001095351.2 |
Mus musculus (house mouse) | Bbox1 | NP_569719.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008246 | XP_317222.4 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012477 | XP_307672.4 |
Homo sapiens (human) | BBOX1 | NP_003977.1 |
Neurospora crassa | NCU06891 | XP_959238.1 |
Xenopus tropicalis (tropical clawed frog) | bbox1 | NP_001120574.1 |
Pan troglodytes (chimpanzee) | BBOX1 | XP_001135704.1 |
Gallus gallus (chicken) | BBOX1 | XP_424543.2 |
Danio rerio (zebrafish) | bbox1 | NP_001017717.1 |
Drosophila melanogaster (fruit fly) | CG5321 | NP_572967.2 |
Drosophila melanogaster (fruit fly) | CG10814 | NP_610868.1 |
Caenorhabditis elegans (roundworm) | gbh-1 | NP_496305.1 |
A high-fat diet increases L-carnitine synthesis through a differential maturation of the Bbox1 mRNAs.
Rigault C, Le Borgne F, Tazir B, Benani A, Demarquoy J
Biochimica et biophysica acta1831(2)370-7(2013 Feb)
The effects of exercise training on ?-butyrobetaine hydroxylase and novel organic cation transporter-2 gene expression in the rat.
Broderick TL, El Midaoui A, Chiasson JL, Wang D, Jankowski M, Gutkowska J
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme36(6)781-9(2011 Dec)
Crystal structure of human gamma-butyrobetaine hydroxylase.
Tars K, Rumnieks J, Zeltins A, Kazaks A, Kotelovica S, Leonciks A, Sharipo J, Viksna A, Kuka J, Liepinsh E, Dambrova M
Biochemical and biophysical research communications398(4)634-9(2010 Aug)
Ontogeny of Na(+)/L-carnitine transporter and of gamma-trimethylaminobutyraldehyde dehydrogenase and gamma-butyrobetaine hydroxylase genes expression in rat kidney.
Garc?a-Delgado M, Peral MJ, Dur?n JM, Garc?a-Miranda P, Calonge ML, Ilund?in AA
Mechanisms of ageing and development130(4)227-33(2009 Apr)
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that expression of BBH mRNA and protein is up-regulated in liver with training in physical activity; in kidney, only BBH mRNA expression is up-regulated.
Title: The effects of exercise training on ?-butyrobetaine hydroxylase and novel organic cation transporter-2 gene expression in the rat.
BBH mRNA, however, was detected during the suckling period onwards and its abundance was not changed significantly by maturation
Title: Ontogeny of Na(+)/L-carnitine transporter and of gamma-trimethylaminobutyraldehyde dehydrogenase and gamma-butyrobetaine hydroxylase genes expression in rat kidney.
Alterations in enzyme activities in the pivalate-treated rats are not regulated at the transcriptional level, and are apparently related to post-transcriptional effects on the enzymes themselves.
Title: Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats.
Thyroid hormone controls carnitine status through modifications of gamma-butyrobetaine hydroxylase activity and gene expression
Title: Thyroid hormone controls carnitine status through modifications of gamma-butyrobetaine hydroxylase activity and gene expression.
The following Bbox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bbox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa06176 | |
Clone ID Related Accession (Same CDS sequence) | NM_022629.1 | |
Accession Version | NM_022629.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | gamma-butyrobetaine dioxygenase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF160958.1. ##Evidence-Data-START## Transcript exon combination :: AF160958.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMEA2689595 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCACTGTG CCATCCTAAA GGCGGAAGCA GTGGATGGGG CTCGCTTGAT GCAGATCTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_072151.1 |
CDS | 1..1164 |
Translation |
Target ORF information:
Target ORF information:
|
NM_022629.1 |
1 | ATGCACTGTG CCATCCTAAA GGCGGAAGCA GTGGATGGGG CTCGCTTGAT GCAGATCTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa60537 | |
Clone ID Related Accession (Same CDS sequence) | XM_017592026.1 | |
Accession Version | XM_017592026.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | gamma-butyrobetaine dioxygenase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) and transcript sequence (NM_022629.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 9 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## |
1 | ATGCACTGTG CCATCTTAAA GGCGGAAGCA GTGGATGGGG CTCGCCTGAT GCAGATCTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017447515.1 |
CDS | 322..1485 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017592026.1 |
1 | ATGCACTGTG CCATCTTAAA GGCGGAAGCA GTGGATGGGG CTCGCCTGAT GCAGATCTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A high-fat diet increases L-carnitine synthesis through a differential maturation of the Bbox1 mRNAs. |
The effects of exercise training on ?-butyrobetaine hydroxylase and novel organic cation transporter-2 gene expression in the rat. |
Crystal structure of human gamma-butyrobetaine hydroxylase. |
Ontogeny of Na(+)/L-carnitine transporter and of gamma-trimethylaminobutyraldehyde dehydrogenase and gamma-butyrobetaine hydroxylase genes expression in rat kidney. |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |