A chimaeric immunoglobulin of human and non-human origin. In order to minimize the possibility of the chimaera being antigenic in humans, only the hypervariable regions of a non-human monoclonal antibody, which are responsible for its specificity, replace the homologous regions of a human immunoglobulin.
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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]