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Synthetic gRNA

Synthetic gRNA (guide RNA) refers to artificially engineered RNA molecules used in CRISPR-Cas gene editing systems. These molecules are designed to guide the CRISPR-Cas enzyme to a specific target DNA sequence within a genome. The guide RNA contains a customizable "targeting sequence" that complements the DNA sequence of interest, allowing the CRISPR-Cas enzyme to bind to the target site and induce a modification in the DNA.

In the CRISPR-Cas system, gRNA is a critical component that determines the specificity of the gene-editing process. By changing the targeting sequence of the synthetic gRNA, researchers can precisely direct the CRISPR-Cas enzyme to edit specific genes, enabling them to add, delete, or modify DNA sequences with high precision. Synthetic gRNA offers great flexibility and efficiency, making it a valuable tool in various genetic engineering applications and biomedical research.


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