slc16a2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	slc16a2
Entrez Gene ID	100884148
Full Name	solute carrier family 16, member 2 (thyroid hormone transporter)
Synonyms	mct8
General protein information	Preferred Names solute carrier family 16, member 2 (thyroid hormone transporter) Names solute carrier family 16, member 2 (thyroid hormone transporter) monocarboxylate transporter 8 solute carrier family 16 (monocarboxylic acid transporters), member 2 solute carrier family 16, member 2, protein
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001258230.1	NP_001245159.1	solute carrier family 16 member 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLC16A2	NP_006508.2
Canis lupus familiaris (dog)	SLC16A2	XP_005641562.1
Mus musculus (house mouse)	Slc16a2	NP_033223.2
	SLC16A2	XP_001096017.1
Danio rerio (zebrafish)	slc16a2	NP_001245159.1
Gallus gallus (chicken)	SLC16A2	XP_426274.2
Bos taurus (cattle)	SLC16A2	NP_001193868.1
Rattus norvegicus (Norway rat)	Slc16a2	NP_671749.1
Xenopus tropicalis (tropical clawed frog)	LOC100494635	XP_002931873.2

Gene Ontology
Bibliography

Related articles in PubMed

Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish.
Zada D, Tovin A, Lerer-Goldshtein T, Appelbaum L
Disease models & mechanisms9(11)1339-1348(2016 11)

Altered behavioral performance and live imaging of circuit-specific neural deficiencies in a zebrafish model for psychomotor retardation.
Zada D, Tovin A, Lerer-Goldshtein T, Vatine GD, Appelbaum L
PLoS genetics10(9)e1004615(2014 Sep)

Maternal thyroid hormones are essential for neural development in zebrafish.
Campinho MA, Saraiva J, Florindo C, Power DM
Molecular endocrinology (Baltimore, Md.)28(7)1136-49(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the cellular and molecular consequences of MCT8 knockdown during embryonic development in zebrafish provides new insight into the potential role of thyroid hormones in X-linked mental retardation in humans.
Title: Maternal thyroid hormones are essential for neural development in zebrafish.

MCT8 is a crucial regulator during embryonic development; zebrafish is a model for MCT8 deficiency that exhibits a neurological phenotype
Title: Zebrafish as a model for monocarboxyl transporter 8-deficiency.

The following slc16a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the slc16a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03728	NM_001258230.1 Latest version!	Danio rerio solute carrier family 16 member 2 (slc16a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	Quote Price

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

slc16a2 ( NM_001258230.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001245159.1 Danio rerio solute carrier family 16 member 2 (slc16a2), mRNA.

Price & Availability↑

CloneID	ODa03728
Clone ID Related Accession (Same CDS sequence)	NM_001258230.1
Accession Version	NM_001258230.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-10
Organism	Danio rerio(zebrafish)
Product	solute carrier family 16 member 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from FN687448.2. ##Evidence-Data-START## Transcript exon combination :: FN687448.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGCACTCGG AAAGCGATGA CAACACGGCT GGTGGGACGC CCGGCTCGGA GGACCCGCAG 
GCTGAGGAGT CCTCTTCCCC TGCGGAGGAG TTCGAGGAGC AGGAGCGCAA GCTGGCCCCG 
GAGGACAGCA CCGTGCAGCT CATACACACC GGCTGCACTG ACAAGCGTCC GGCCACGCCG 
CCTGGCGCTC ACCCTGGTCA AGGCTTCGTT CCCCCGGAGG GGGGCTTCGG TTGGGTCGTG 
GTGTTCGCTG CTACATGGTG CAACGGCTCG ATTTTCGGCA TCCAGAACTC ATTCGGGATT 
CTGCACATGA TGCTGGTGAA GCACCACGAG AAGCAGCCGG ACCAGGCGTC TCAGTTTAAA 
GTGGCCTGGG TCGGTGCGCT GGCGATGGGC ATGATCTTCT TCTGTTCTCC TGTGGTCAGT 
ATGTTCACCG ATCACTTCGG ATGTCGGAAA ACGGCTGTGT GTGGAGCGTT TGTGGCCTTC 
ATCGGTCTCC TCACCAGCTC CTTCGCCACG ACTCTGGGTC TCTGGTACTT CACGTATGGG 
ATTCTCTTCG GCTGCGGCTC TTCGTTTGCA TTCCAGCCAT CTCTGGTGAT CCTGGGTCAT 
TATTTCCGCC AGCGTCTGGG TTTGGCGAAT GGTGTGGTGA CGGCGGGCAG CAGTCTGTTC 
TCCATGGGGC TGCCGGTGCT GTTGAAGAAA GTGGTGGAGC CGCTGGGTTT GCCCAGAACC 
TTTCAGATCC TCAGTATCTT CATGCTGGTG CAGGCGCTGC TGGCCCTGGC CTTCAAACCG 
CTCCTGCCCA GCGGCATGTG CCCGATGCCT GGCATGGCGC TGGACGGAGG GCCCTCGACT 
CCAGAGTCAG CCAGCAGGTG GCAGAAGGGA CTGGCCAAAA TCAGGAGGTA CTTCAACGTG 
CGGGTGTTCA GCATTCTGAC GTACCGCATC TGGGCCTTTG GCGTCGCCAC TGCTGTGCTC 
GGATACTTCG TGCCCTACGT TCACCTGTTG AACTTCGTGA AGGAGCAGTT TGGAGACACT 
CAGAGGGAAT GGCTGCTGCT GGTGTGCATC GGAGCTTCGT CTGGAGTCGG GCGACTGCTG 
TTCGGGAAGA TCGGAGACCT CATACCTGGA GTCAAGAAGA TCTACATGCA GGTGGCCTCC 
TTCATATTGC TGGGCGTGAT GTCCATGATG ATTCCTCAGT GTGCCGTGTT TGAGGGTCTG 
GTGGTGGTTT TCGTGCTGAT GGGTCTTTGC GACGGCTGTT TCATCACGAT TATGGCCCCC 
ATTGCCTTCG AGCTGGTTGG ACCCATGCAG GCGTCACAGG CCATCGGGTA CCTGCTGGGA 
CTCATGGCCA TACCCATGAC TGCAGGACCA CCCATCGCAG GTCTCCTTCA TGATCACTTC 
GGGAACTACC ATGTGGCGTT TTACCTGGCT GGCGTCCCTC CGATCGTGGG GGGAATTGTG 
ATGTTTTTCG TGCCTCTGGT CCACCAGCGA ATGCAGAAAC GGAGGAAAGA GACCGACGAT 
CCCAGCATGG ACAAAATGCT GAAGAACTGC TCTAATGGAG ACATGCTGCC AGGATACACA 
GACATGGAGA CACACATATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245159.1
CDS	1..1581
Translation	MHSESDDNTAGGTPGSEDPQAEESSSPAEEFEEQERKLAPEDSTVQLIHTGCTDKRPATPPGAHPGQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCGSSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGMALDGGPSTPESASRWQKGLAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIYMQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNYHVAFYLAGVPPIVGGIVMFFVPLVHQRMQKRRKETDDPSMDKMLKNCSNGDMLPGYTDMETHI

Target ORF information:

RefSeq Version	NM_001258230.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio solute carrier family 16 member 2 (slc16a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258230.1

ORF Insert Sequence:

ATGCACTCGG AAAGCGATGA CAACACGGCT GGTGGGACGC CCGGCTCGGA GGACCCGCAG 
GCTGAGGAGT CCTCTTCCCC TGCGGAGGAG TTCGAGGAGC AGGAGCGCAA GCTGGCCCCG 
GAGGACAGCA CCGTGCAGCT CATACACACC GGCTGCACTG ACAAGCGTCC GGCCACGCCG 
CCTGGCGCTC ACCCTGGTCA AGGCTTCGTT CCCCCGGAGG GGGGCTTCGG TTGGGTCGTG 
GTGTTCGCTG CTACATGGTG CAACGGCTCG ATTTTCGGCA TCCAGAACTC ATTCGGGATT 
CTGCACATGA TGCTGGTGAA GCACCACGAG AAGCAGCCGG ACCAGGCGTC TCAGTTTAAA 
GTGGCCTGGG TCGGTGCGCT GGCGATGGGC ATGATCTTCT TCTGTTCTCC TGTGGTCAGT 
ATGTTCACCG ATCACTTCGG ATGTCGGAAA ACGGCTGTGT GTGGAGCGTT TGTGGCCTTC 
ATCGGTCTCC TCACCAGCTC CTTCGCCACG ACTCTGGGTC TCTGGTACTT CACGTATGGG 
ATTCTCTTCG GCTGCGGCTC TTCGTTTGCA TTCCAGCCAT CTCTGGTGAT CCTGGGTCAT 
TATTTCCGCC AGCGTCTGGG TTTGGCGAAT GGTGTGGTGA CGGCGGGCAG CAGTCTGTTC 
TCCATGGGGC TGCCGGTGCT GTTGAAGAAA GTGGTGGAGC CGCTGGGTTT GCCCAGAACC 
TTTCAGATCC TCAGTATCTT CATGCTGGTG CAGGCGCTGC TGGCCCTGGC CTTCAAACCG 
CTCCTGCCCA GCGGCATGTG CCCGATGCCT GGCATGGCGC TGGACGGAGG GCCCTCGACT 
CCAGAGTCAG CCAGCAGGTG GCAGAAGGGA CTGGCCAAAA TCAGGAGGTA CTTCAACGTG 
CGGGTGTTCA GCATTCTGAC GTACCGCATC TGGGCCTTTG GCGTCGCCAC TGCTGTGCTC 
GGATACTTCG TGCCCTACGT TCACCTGTTG AACTTCGTGA AGGAGCAGTT TGGAGACACT 
CAGAGGGAAT GGCTGCTGCT GGTGTGCATC GGAGCTTCGT CTGGAGTCGG GCGACTGCTG 
TTCGGGAAGA TCGGAGACCT CATACCTGGA GTCAAGAAGA TCTACATGCA GGTGGCCTCC 
TTCATATTGC TGGGCGTGAT GTCCATGATG ATTCCTCAGT GTGCCGTGTT TGAGGGTCTG 
GTGGTGGTTT TCGTGCTGAT GGGTCTTTGC GACGGCTGTT TCATCACGAT TATGGCCCCC 
ATTGCCTTCG AGCTGGTTGG ACCCATGCAG GCGTCACAGG CCATCGGGTA CCTGCTGGGA 
CTCATGGCCA TACCCATGAC TGCAGGACCA CCCATCGCAG GTCTCCTTCA TGATCACTTC 
GGGAACTACC ATGTGGCGTT TTACCTGGCT GGCGTCCCTC CGATCGTGGG GGGAATTGTG 
ATGTTTTTCG TGCCTCTGGT CCACCAGCGA ATGCAGAAAC GGAGGAAAGA GACCGACGAT 
CCCAGCATGG ACAAAATGCT GAAGAACTGC TCTAATGGAG ACATGCTGCC AGGATACACA 
GACATGGAGA CACACATATG A