ORF cDNA Clones and Custom Clones » Species Summary » Danio rerio » fscn2b cDNA ORF clone

fscn2b cDNA ORF clone, Danio rerio(zebrafish)

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Summary

Gene Symbol	fscn2b
Entrez Gene ID	393743
Full Name	fascin actin-bundling protein 2b, retinal
Synonyms	fscn1l,fscn2,zgc:73272
General protein information	Preferred Names fascin actin-bundling protein 2b, retinal Names fascin-2 fascin 2B fascin homolog 1-like, actin-bundling protein fascin homolog 2, actin-bundling protein, retinal b
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200770.2	NP_957064.2	fascin-2

Homologies

Canis lupus familiaris (dog)	FSCN2	XP_003435223.1
Rattus norvegicus (Norway rat)	Fscn2	NP_001100542.1
Drosophila melanogaster (fruit fly)	sn	NP_001162696.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012991	XP_003437121.1
Pan troglodytes (chimpanzee)	FSCN2	XP_003953273.1
Gallus gallus (chicken)	FSCN2	NP_001171209.1
Danio rerio (zebrafish)	fscn2a	NP_001116988.1
Homo sapiens (human)	FSCN2	NP_001070650.1
	FSCN2	XP_001110926.2
Mus musculus (house mouse)	Fscn2	NP_766390.2
Danio rerio (zebrafish)	fscn2b	NP_957064.2
Xenopus tropicalis (tropical clawed frog)	fscn2	NP_001093724.1
Bos taurus (cattle)	FSCN2	NP_788806.1

Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells.
Pollock LM, Gupta N, Chen X, Luna EJ, McDermott BM Jr
PloS one11(7)e0158349(2016)

The Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In?Vivo.
Hwang P, Chou SW, Chen Z, McDermott BM Jr
Cell reports13(7)1287-1294(2015 Nov)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein.
Gopal SR, Chen DH, Chou SW, Zang J, Neuhauss SC, Stepanyan R, McDermott BM Jr, Alagramam KN
The Journal of neuroscience : the official journal of the Society for Neuroscience35(28)10188-201(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

fascin 2b plays a key role in shaping stereocilia
Title: Fascin 2b is a component of stereocilia that lengthens actin-based protrusions.

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The following fscn2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fscn2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03883	NM_200770.2 Latest version!	Danio rerio fascin actin-bundling protein 2b, retinal (fscn2b), mRNA.	pcDNA3.1⁺/C-(K)DYK or customized vector	9-11	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

fscn2b ( NM_200770.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_957064.2 Danio rerio fascin actin-bundling protein 2b, retinal (fscn2b), mRNA.

Price & Availability↑

CloneID	ODa03883
Clone ID Related Accession (Same CDS sequence)	NM_200770.2
Accession Version	NM_200770.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1⁺/C-(K)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	fascin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU580143.1. On Apr 21, 2008 this sequence version replaced NM_200770.1. ##Evidence-Data-START## Transcript exon combination :: EU580143.1, EE203503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505384, SAMEA4476741 [ECO:0000348] ##Evidence-Data-END##

ATGCCCTCCA ATGGCACCAA AGCCCTTAAG CTTCAATTCG GGCTTATTAA TCATGAGAAT 
CGCTACCTAA CGGCGGAGGC CTTCGGCTTC AAGGTGAACG CTTCAGCTCC AAGCCTCAAG 
AAGAAGCAGA TCTGGACTCT AGAGCAAGAC GATCAGGATG GTCAGGTGGT TTACCTTCGT 
AGTCACCTAG GGCGCTACCT GGCCTCTGAC AAAGATGGCA AGGTAAGCTG TGAGGCTGAG 
ACTAAAGAGA ATGACTGTCG CTTTTTGATT GTGGCACAGT CAGATGGCCG CTGGGCCCTG 
CAGTCTGAGA CATATTTGCG CTTTTTCGGA GGTTCAGAAG ACTACTTGTC GTGCTTTGCT 
CAGACAATAG GTGAGGCAGA ACTATGGGCC ATGCATCTAG CCCTACACCC ACAAGCTAAT 
CTGCTTAGTG TGGCCCGCAA ACGATATGCC CACTTGGCAT CGCCAGAGGG AGAGATTGCT 
GTAGACTGCA ACATCCCATG GGGTGTTGAT GCACTTCTAA CTCTTGTGTA CATGGACGGC 
AAATATTGTC TTAAGACCAG TGACAGCCGC TTCCTTAGCA ATGATGGGAA ACTGTCCTCT 
GAAAATGGAC GTGGCACAGG CTACACCTTG GAACTGAAAT CAGGCAAATT GGCCTTCAAG 
GACTGTGAGG GGAAGTACTT GACCCCCATG GGGCCCACTG GAACTCTGCG CTCTGGACGA 
TGCTCCAAAC CTGGCAAAGA TGAGCTGTTT GATCTTGAGG AAAGCCATCC GCAAGTGGTG 
TTTCAGGCCG CCAACAACAG ATTTGTCTCC ATTCGACAGG GTGTGAGCGT CTCAGCCAAT 
CAGGACGATG AGACAGACAT GGAGACGTTT CAAATGGAAA TTGATAAAGA TACGAGAAAG 
TGCAAATTCA GAACCAATGA AGGAAATTAT TGGACGCTCG TCGCTCATGG GGGCATCCAG 
TCAACAGCCA CAGAAGCCGG TGCCAACACC ATGTTTGACA TCGTGTGGCT CGGTCGACGG 
GTGGCACTGC GGGCCAGCAA TGGAAAATAT GTATGTACTA AGAAAAACGG CCAGCTTTCT 
GCAGTCAGCG ACTCTGTGGG CGAGGACGAG CAGCTGATTC TGAAGCTGAT CAACAGGCCC 
ATTCTGATCC TGAGGGGAGA AAACGGCTAT GTTTGCCACC ACAAAAACTC AAACACGCTG 
GACGCCAGTC GCTCGGTTTA TGACATTTTC ACACTGCAGT TCAGTGATGG TGCATACCAT 
ATTAAAGGTG CTGGCGGGAA ATTCTGGTAT GTGTCCAGCA GTGGTTWGGT GTGTTCAGAC 
GGAGACACGC CTGAGGATTT CAGCTTTGAG TTCTTAGAGC ACGGACGAAT AGCGATTAGA 
GGCAAAAACG GCAAATACCT GCGGGGAGAT CAGGGCGGGA ATCTGAAAGG AGACGGAGAG 
ACGGCGGACA GCTCTTCCCT CTGGGAATAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_957064.2
CDS	1..1473
Translation	MPSNGTKALKLQFGLINHENRYLTAEAFGFKVNASAPSLKKKQIWTLEQDDQDGQVVYLRSHLGRYLASDKDGKVSCEAETKENDCRFLIVAQSDGRWALQSETYLRFFGGSEDYLSCFAQTIGEAELWAMHLALHPQANLLSVARKRYAHLASPEGEIAVDCNIPWGVDALLTLVYMDGKYCLKTSDSRFLSNDGKLSSENGRGTGYTLELKSGKLAFKDCEGKYLTPMGPTGTLRSGRCSKPGKDELFDLEESHPQVVFQAANNRFVSIRQGVSVSANQDDETDMETFQMEIDKDTRKCKFRTNEGNYWTLVAHGGIQSTATEAGANTMFDIVWLGRRVALRASNGKYVCTKKNGQLSAVSDSVGEDEQLILKLINRPILILRGENGYVCHHKNSNTLDASRSVYDIFTLQFSDGAYHIKGAGGKFWYVSSSGnullVCSDGDTPEDFSFEFLEHGRIAIRGKNGKYLRGDQGGNLKGDGETADSSSLWEY

Target ORF information:

RefSeq Version	NM_200770.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio fascin actin-bundling protein 2b, retinal (fscn2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200770.2

ORF Insert Sequence:

ATGCCCTCCA ATGGCACCAA AGCCCTTAAG CTTCAATTCG GGCTTATTAA TCATGAGAAT 
CGCTACCTAA CGGCGGAGGC CTTCGGCTTC AAGGTGAACG CTTCAGCTCC AAGCCTCAAG 
AAGAAGCAGA TCTGGACTCT AGAGCAAGAC GATCAGGATG GTCAGGTGGT TTACCTTCGT 
AGTCACCTAG GGCGCTACCT GGCCTCTGAC AAAGATGGCA AGGTAAGCTG TGAGGCTGAG 
ACTAAAGAGA ATGACTGTCG CTTTTTGATT GTGGCACAGT CAGATGGCCG CTGGGCCCTG 
CAGTCTGAGA CATATTTGCG CTTTTTCGGA GGTTCAGAAG ACTACTTGTC GTGCTTTGCT 
CAGACAATAG GTGAGGCAGA ACTATGGGCC ATGCATCTAG CCCTACACCC ACAAGCTAAT 
CTGCTTAGTG TGGCCCGCAA ACGATATGCC CACTTGGCAT CGCCAGAGGG AGAGATTGCT 
GTAGACTGCA ACATCCCATG GGGTGTTGAT GCACTTCTAA CTCTTGTGTA CATGGACGGC 
AAATATTGTC TTAAGACCAG TGACAGCCGC TTCCTTAGCA ATGATGGGAA ACTGTCCTCT 
GAAAATGGAC GTGGCACAGG CTACACCTTG GAACTGAAAT CAGGCAAATT GGCCTTCAAG 
GACTGTGAGG GGAAGTACTT GACCCCCATG GGGCCCACTG GAACTCTGCG CTCTGGACGA 
TGCTCCAAAC CTGGCAAAGA TGAGCTGTTT GATCTTGAGG AAAGCCATCC GCAAGTGGTG 
TTTCAGGCCG CCAACAACAG ATTTGTCTCC ATTCGACAGG GTGTGAGCGT CTCAGCCAAT 
CAGGACGATG AGACAGACAT GGAGACGTTT CAAATGGAAA TTGATAAAGA TACGAGAAAG 
TGCAAATTCA GAACCAATGA AGGAAATTAT TGGACGCTCG TCGCTCATGG GGGCATCCAG 
TCAACAGCCA CAGAAGCCGG TGCCAACACC ATGTTTGACA TCGTGTGGCT CGGTCGACGG 
GTGGCACTGC GGGCCAGCAA TGGAAAATAT GTATGTACTA AGAAAAACGG CCAGCTTTCT 
GCAGTCAGCG ACTCTGTGGG CGAGGACGAG CAGCTGATTC TGAAGCTGAT CAACAGGCCC 
ATTCTGATCC TGAGGGGAGA AAACGGCTAT GTTTGCCACC ACAAAAACTC AAACACGCTG 
GACGCCAGTC GCTCGGTTTA TGACATTTTC ACACTGCAGT TCAGTGATGG TGCATACCAT 
ATTAAAGGTG CTGGCGGGAA ATTCTGGTAT GTGTCCAGCA GTGGTTWGGT GTGTTCAGAC 
GGAGACACGC CTGAGGATTT CAGCTTTGAG TTCTTAGAGC ACGGACGAAT AGCGATTAGA 
GGCAAAAACG GCAAATACCT GCGGGGAGAT CAGGGCGGGA ATCTGAAAGG AGACGGAGAG 
ACGGCGGACA GCTCTTCCCT CTGGGAATAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells.
PloS one11(7)e0158349(2016)
Pollock LM,Gupta N,Chen X,Luna EJ,McDermott BM Jr

The Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In?Vivo.
Cell reports13(7)1287-1294(2015 Nov)
Hwang P,Chou SW,Chen Z,McDermott BM Jr

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(28)10188-201(2015 Jul)
Gopal SR,Chen DH,Chou SW,Zang J,Neuhauss SC,Stepanyan R,McDermott BM Jr,Alagramam KN

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fscn2b cDNA ORF clone, Danio rerio(zebrafish)

Summary

Reference Sequences (RefSeq)

Pathways from BioSystems

Homologies

Gene Ontology

Bibliography

Reference Sequences (Refseq)

Target ORF information:

Target ORF information:

ORF Insert Sequence:

PubMed

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