hexim1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	hexim1
Entrez Gene ID	562319
Full Name	hexamethylene bis-acetamide inducible 1
Synonyms	fd44h02,hexim,wu:fd44h02,zgc:162976
General protein information	Preferred Names hexamethylene bis-acetamide inducible 1 Names protein HEXIM
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098389.1	NP_001091859.1	protein HEXIM

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	hexim1	NP_001091859.1
Xenopus tropicalis (tropical clawed frog)	LOC100497839	XP_002935563.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-Andr? V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI
Molecular cell62(1)34-46(2016 Apr)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish.
McGrail M, Hatler JM, Kuang X, Liao HK, Nannapaneni K, Watt KE, Uhl JD, Largaespada DA, Vollbrecht E, Scheetz TE, Dupuy AJ, Hostetter JM, Essner JJ
PloS one6(4)e18826(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following hexim1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hexim1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa38610	NM_001098389.1 Latest version!	Danio rerio HEXIM P-TEFb complex subunit 1 (hexim1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

hexim1 ( NM_001098389.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001091859.1 Danio rerio HEXIM P-TEFb complex subunit 1 (hexim1), mRNA.

Price & Availability↑

CloneID	ODa38610
Clone ID Related Accession (Same CDS sequence)	NM_001098389.1
Accession Version	NM_001098389.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-07
Organism	Danio rerio(zebrafish)
Product	protein HEXIM
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC141797.1. On May 30, 2007 this sequence version replaced XM_685708.2. ##Evidence-Data-START## Transcript exon combination :: BC141797.1, EH545596.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCTTA TTAAAGAAGA AACTGCACCG GAGGATGACA GCAGGGGGCG GCAGAGAGAT 
TGTCGGACGA GTGTTGTGTC CTCGAAACAA GTGCAAAGAA ATCAGTTGGA GATTTGTCCT 
GGTTTGGTGT CAGGAGATGT GCATCCAATG TGTCGGGATC GGAGTGATCC TGAGCCCAGG 
ACTGGCGATG CAGCAAGTGA CGACGGGTTT CCTGCAGACA AAACGAGTAG TAAGAGAGAC 
TCTGAATGCG CGGCAGTAAA CACCGATGGG GTGTCTGATG GCCGCCAGGG CAAAAAGAAA 
CACAGACGGC GACCCTCCAA GAAGAAGCGC CGCTGGAAGC CGTATTTTAA ACTGACATGG 
GAGGAGAAAA AAGAGCTGGA TGAACGCGAG ACCGCGCGGG CGTCGCGAGT GCGCGCCGAA 
ATGTTCGCTA AAGGTCTCCC CGTCGCACCG TACAACACCA CCCAGTTCCT AATGGAGGAG 
CACGACCGTG AAGAACCCGA TCTCAACACT GAGCTGGGAG GTCGAAAATC CGGGGCAATC 
CGCTCCGAGG ACACGGCCAG TGAGGACGAG AATTTCGAGG CTGAAGAGGA CGACGAGGAG 
GAAGGCGGCG GAGGTAGCGA CGGTATGGGA AGACCAGGGC AAGCAGGTGG GGAGTTTTTG 
CAGAAGGACT TTTCTGAGAC CTATGAGAAG TACCATGTAG AGGCGCTTCA GAATATGTCT 
AAACAAGAAC TAGTCCGGGA ATACCTGGAG CTGGAGAAGT GCATGTCGCG GTTAGAAGAG 
GAGAACAACT GGCTTCGCCA CGTCCGGAGA AACCCCGAGT CCCCTGCTGA CGGGACTGGC 
TCCCAGCGCG TGCGAGAACT GGAGGTTGAA GTGGAGAAAC TGAGGGCCGA GAATAACGAG 
TTATTACTAA AAACGCCCGC AAGTAATGAG CCAGGACTCA ATCAGTCTCA GCCGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091859.1
CDS	157..1116
Translation	MELIKEETAPEDDSRGRQRDCRTSVVSSKQVQRNQLEICPGLVSGDVHPMCRDRSDPEPRTGDAASDDGFPADKTSSKRDSECAAVNTDGVSDGRQGKKKHRRRPSKKKRRWKPYFKLTWEEKKELDERETARASRVRAEMFAKGLPVAPYNTTQFLMEEHDREEPDLNTELGGRKSGAIRSEDTASEDENFEAEEDDEEEGGGGSDGMGRPGQAGGEFLQKDFSETYEKYHVEALQNMSKQELVREYLELEKCMSRLEEENNWLRHVRRNPESPADGTGSQRVRELEVEVEKLRAENNELLLKTPASNEPGLNQSQPS

Target ORF information:

RefSeq Version	NM_001098389.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio HEXIM P-TEFb complex subunit 1 (hexim1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098389.1

ORF Insert Sequence:

ATGGAGCTTA TTAAAGAAGA AACTGCACCG GAGGATGACA GCAGGGGGCG GCAGAGAGAT 
TGTCGGACGA GTGTTGTGTC CTCGAAACAA GTGCAAAGAA ATCAGTTGGA GATTTGTCCT 
GGTTTGGTGT CAGGAGATGT GCATCCAATG TGTCGGGATC GGAGTGATCC TGAGCCCAGG 
ACTGGCGATG CAGCAAGTGA CGACGGGTTT CCTGCAGACA AAACGAGTAG TAAGAGAGAC 
TCTGAATGCG CGGCAGTAAA CACCGATGGG GTGTCTGATG GCCGCCAGGG CAAAAAGAAA 
CACAGACGGC GACCCTCCAA GAAGAAGCGC CGCTGGAAGC CGTATTTTAA ACTGACATGG 
GAGGAGAAAA AAGAGCTGGA TGAACGCGAG ACCGCGCGGG CGTCGCGAGT GCGCGCCGAA 
ATGTTCGCTA AAGGTCTCCC CGTCGCACCG TACAACACCA CCCAGTTCCT AATGGAGGAG 
CACGACCGTG AAGAACCCGA TCTCAACACT GAGCTGGGAG GTCGAAAATC CGGGGCAATC 
CGCTCCGAGG ACACGGCCAG TGAGGACGAG AATTTCGAGG CTGAAGAGGA CGACGAGGAG 
GAAGGCGGCG GAGGTAGCGA CGGTATGGGA AGACCAGGGC AAGCAGGTGG GGAGTTTTTG 
CAGAAGGACT TTTCTGAGAC CTATGAGAAG TACCATGTAG AGGCGCTTCA GAATATGTCT 
AAACAAGAAC TAGTCCGGGA ATACCTGGAG CTGGAGAAGT GCATGTCGCG GTTAGAAGAG 
GAGAACAACT GGCTTCGCCA CGTCCGGAGA AACCCCGAGT CCCCTGCTGA CGGGACTGGC 
TCCCAGCGCG TGCGAGAACT GGAGGTTGAA GTGGAGAAAC TGAGGGCCGA GAATAACGAG 
TTATTACTAA AAACGCCCGC AAGTAATGAG CCAGGACTCA ATCAGTCTCA GCCGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Molecular cell62(1)34-46(2016 Apr)
Tan JL,Fogley RD,Flynn RA,Ablain J,Yang S,Saint-Andr? V,Fan ZP,Do BT,Laga AC,Fujinaga K,Santoriello C,Greer CB,Kim YJ,Clohessy JG,Bothmer A,Pandell N,Avagyan S,Brogie JE,van Rooijen E,Hagedorn EJ,Shyh-Chang N,White RM,Price DH,Pandolfi PP,Peterlin BM,Zhou Y,Kim TH,Asara JM,Chang HY,Young RA,Zon LI

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish.
PloS one6(4)e18826(2011 Apr)
McGrail M,Hatler JM,Kuang X,Liao HK,Nannapaneni K,Watt KE,Uhl JD,Largaespada DA,Vollbrecht E,Scheetz TE,Dupuy AJ,Hostetter JM,Essner JJ

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hexim1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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