CSNK1A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	CSNK1A1
Entrez Gene ID	1452
Full Name	casein kinase 1 alpha 1
Synonyms	CK1,CK1a,CKIa,HEL-S-77p,HLCDGP1,PRO2975
General protein information	Preferred Names casein kinase 1 alpha 1 Names casein kinase I isoform alpha CKI-alpha clock regulator kinase down-regulated in lung cancer epididymis secretory sperm binding protein Li 77p
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q32
Disorder MIM:	600505

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271741.1	NP_001258670.1	casein kinase I isoform alpha isoform 3
NM_001271741.2	NP_001258670.1	casein kinase I isoform alpha isoform 3
NM_001892.6	NP_001883.4	casein kinase I isoform alpha isoform 2
NM_001025105.3	NP_001020276.1	casein kinase I isoform alpha isoform 1
NM_001892.5	NP_001883.4	casein kinase I isoform alpha isoform 2
NM_001025105.2	NP_001020276.1	casein kinase I isoform alpha isoform 1
NM_001271742.1	NP_001258671.1	casein kinase I isoform alpha isoform 4
NM_001271742.2	NP_001258671.1	casein kinase I isoform alpha isoform 4

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CSNK1A1	NP_777136.1
Gallus gallus (chicken)	CSNK1A1	NP_990384.1
Arabidopsis thaliana (thale cress)	ckl8	NP_199146.1
Arabidopsis thaliana (thale cress)	ADK1	NP_563695.2
Canis lupus familiaris (dog)	CSNK1A1	XP_005619366.1
Schizosaccharomyces pombe (fission yeast)	hhp2	NP_593184.1
Oryza sativa (rice)	Os02g0810400	NP_001048470.1
Oryza sativa (rice)	Os04g0514800	NP_001053309.1
Xenopus tropicalis (tropical clawed frog)	csnk1a1	NP_001001221.1
	CSNK1A1	XP_001106904.1
Rattus norvegicus (Norway rat)	Csnk1a1	NP_446067.1
Danio rerio (zebrafish)	LOC100334765	XP_002664490.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000627	XP_001238805.2
Arabidopsis thaliana (thale cress)	CKL13	NP_171939.1
Arabidopsis thaliana (thale cress)	CKI1	NP_193170.1
Arabidopsis thaliana (thale cress)	ckl7	NP_199223.1
Pan troglodytes (chimpanzee)	CSNK1A1	XP_001163959.1
Drosophila melanogaster (fruit fly)	CkIalpha	NP_001162737.1
Arabidopsis thaliana (thale cress)	ckl10	NP_188976.1
Oryza sativa (rice)	Os02g0622100	NP_001047465.1
Homo sapiens (human)	CSNK1A1	NP_001020276.1
Mus musculus (house mouse)	Csnk1a1	NP_666199.1
Arabidopsis thaliana (thale cress)	CKL6	NP_567812.1

Gene Ontology
Bibliography

Related articles in PubMed

Casein kinase 1? mediates degradation of receptors for type I and type II interferons caused by hemagglutinin of influenza A virus.
Xia C, Wolf JJ, Vijayan M, Studstill CJ, Ma W, Hahm B
Journal of virology(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Maintenance of the progenitors thus requires cooperation by PRMT1 and CSNK1a1 to sustain proliferation gene expression and suppress premature differentiation driven by GRHL3
Title: CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue.

Disruption of CK1alpha function in myeloma cells resulted in decreased Mdm2, increased p53 and p21 and reduced expression of beta-catenin and AKT.
Title: Inactivation of CK1? in multiple myeloma empowers drug cytotoxicity by affecting AKT and ?-catenin survival signaling pathways.

casein kinase 1 phosphorylates the SQSTM1 S349 residue when harmful proteins accumulate under HSF1 stress
Title: HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis.

CK1delta enhances EPO secretion from liver cancer cells under hypoxia by modifying HIF-2alpha and promoting its nuclear accumulation.
Title: HIF-2? phosphorylation by CK1? promotes erythropoietin secretion in liver cancer cells under hypoxia.

CKIalpha-mediated NS5A S235 phosphorylation is critical for HCV replication. CaMKII gamma and delta may have negative roles in the HCV life cycle.
Title: Phosphorylation of Serine 235 of the Hepatitis C Virus Non-Structural Protein NS5A by Multiple Kinases.

The following CSNK1A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSNK1A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03737	NM_001892.6 Latest version!	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu03879	NM_001271741.2 Latest version!	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03880	NM_001271742.2 Latest version!	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu10853	NM_001025105.3 Latest version!	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
View Old Accession Versions >>
OHu03879	NM_001271741.1	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03737	NM_001892.5	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10853	NM_001025105.2	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu03880	NM_001271742.1	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CSNK1A1 ( NM_001892.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_001883.4 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03737
Clone ID Related Accession (Same CDS sequence)	NM_001892.6 , NM_001892.5
Accession Version	NM_001892.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA144898.1, BC008717.2, L37042.1, BC009186.2, BU618830.1 and AC021078.5. On Jun 2, 2019 this sequence version replaced NM_001892.5. Transcript Variant: This variant (2) lacks an in-frame internal exon, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.1592500.1, SRR1803617.77686.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GCAAGCAAAC TGACAAAACC AAGAGTAACA TGAAAGGTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001883.4
CDS	476..1489
Translation	MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF

Target ORF information:

RefSeq Version	NM_001892.6
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001892.6

ORF Insert Sequence:

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GCAAGCAAAC TGACAAAACC AAGAGTAACA TGAAAGGTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001892.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001883.4 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03737
Clone ID Related Accession (Same CDS sequence)	NM_001892.6 , NM_001892.5
Accession Version	NM_001892.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA144898.1, BC008717.2, L37042.1, BC009186.2 and BU618830.1. On Nov 14, 2012 this sequence version replaced NM_001892.4. Transcript Variant: This variant (2) lacks an in-frame internal exon, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.255486.1, SRR1660805.96073.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GCAAGCAAAC TGACAAAACC AAGAGTAACA TGAAAGGTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001883.4
CDS	589..1602
Translation	MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF

Target ORF information:

RefSeq Version	NM_001892.5
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001892.5

ORF Insert Sequence:

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GCAAGCAAAC TGACAAAACC AAGAGTAACA TGAAAGGTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001271741.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258670.1 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03879
Clone ID Related Accession (Same CDS sequence)	NM_001271741.1 , NM_001271741.2
Accession Version	NM_001271741.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA144898.1, AF218004.1, BC009186.2, BC008717.2 and BU618830.1. Transcript Variant: This variant (3) lacks an in-frame internal exon and uses an alternate splice site, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.202858.1, SRR1803612.146050.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258670.1
CDS	589..1566
Translation	MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGF

Target ORF information:

RefSeq Version	NM_001271741.1
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271741.1

ORF Insert Sequence:

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001271741.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258670.1 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03879
Clone ID Related Accession (Same CDS sequence)	NM_001271741.1 , NM_001271741.2
Accession Version	NM_001271741.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA144898.1, AF218004.1, BC009186.2, BC008717.2, BU618830.1 and AC021078.5. On Jun 2, 2019 this sequence version replaced NM_001271741.1. Transcript Variant: This variant (3) lacks an in-frame internal exon and uses an alternate splice site, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.196450.1, SRR1803616.195679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258670.1
CDS	476..1453
Translation	MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGF

Target ORF information:

RefSeq Version	NM_001271741.2
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271741.2

ORF Insert Sequence:

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTTAT TCCTTATTGA TTTTGGTTTG 
GCCAAAAAGT ACAGAGACAA CAGGACAAGG CAACACATAC CATACAGAGA AGATAAAAAC 
CTCACTGGCA CTGCCCGATA TGCTAGCATC AATGCACATC TTGGTATTGA GCAGAGTCGC 
CGAGATGACA TGGAATCATT AGGATATGTT TTGATGTATT TTAATAGAAC CAGCCTGCCA 
TGGCAAGGGC TAAAGGCTGC AACAAAGAAA CAAAAATATG AAAAGATTAG TGAAAAGAAG 
ATGTCCACGC CTGTTGAAGT TTTATGTAAG GGGTTTCCTG CAGAATTTGC GATGTACTTA 
AACTATTGTC GTGGGCTACG CTTTGAGGAA GCCCCAGATT ACATGTATCT GAGGCAGCTA 
TTCCGCATTC TTTTCAGGAC CCTGAACCAT CAATATGACT ACACATTTGA TTGGACAATG 
TTAAAGCAGA AAGCAGCACA GCAGGCAGCC TCTTCCAGTG GGCAGGGTCA GCAGGCCCAA 
ACCCCCACAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001271742.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258671.1 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu03880
Clone ID Related Accession (Same CDS sequence)	NM_001271742.1 , NM_001271742.2
Accession Version	NM_001271742.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY119498.1, AK293761.1, BC008717.2 and BU618830.1. Transcript Variant: This variant (4) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (4) with a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293761.1, SRR1660809.157032.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCTTC TGGGACCTAG CCTCGAAGAC CTCTTCAATT TCTGTTCAAG AAGGTTCACA 
ATGAAAACTG TACTTATGTT AGCTGACCAG ATGATCAGTA GAATTGAATA TGTGCATACA 
AAGAATTTTA TACACAGAGA CATTAAACCA GATAACTTCC TAATGGGTAT TGGGCGTCAC 
TGTAATAAGT GTTTAGAATC TCCAGTGGGG AAGAGGAAAA GAAGCATGAC TGTTAGTACT 
TCTCAGGACC CATCTTTCTC AGGATTAAAC CAGTTATTCC TTATTGATTT TGGTTTGGCC 
AAAAAGTACA GAGACAACAG GACAAGGCAA CACATACCAT ACAGAGAAGA TAAAAACCTC 
ACTGGCACTG CCCGATATGC TAGCATCAAT GCACATCTTG GTATTGAGCA GAGTCGCCGA 
GATGACATGG AATCATTAGG ATATGTTTTG ATGTATTTTA ATAGAACCAG CCTGCCATGG 
CAAGGGCTAA AGGCTGCAAC AAAGAAACAA AAATATGAAA AGATTAGTGA AAAGAAGATG 
TCCACGCCTG TTGAAGTTTT ATGTAAGGGG TTTCCTGCAG AATTTGCGAT GTACTTAAAC 
TATTGTCGTG GGCTACGCTT TGAGGAAGCC CCAGATTACA TGTATCTGAG GCAGCTATTC 
CGCATTCTTT TCAGGACCCT GAACCATCAA TATGACTACA CATTTGATTG GACAATGTTA 
AAGCAGAAAG CAGCACAGCA GGCAGCCTCT TCCAGTGGGC AGGGTCAGCA GGCCCAAACC 
CCCACAGGCA AGCAAACTGA CAAAACCAAG AGTAACATGA AAGGTTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258671.1
CDS	295..1125
Translation	MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF

Target ORF information:

RefSeq Version	NM_001271742.1
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271742.1

ORF Insert Sequence:

ATGGATCTTC TGGGACCTAG CCTCGAAGAC CTCTTCAATT TCTGTTCAAG AAGGTTCACA 
ATGAAAACTG TACTTATGTT AGCTGACCAG ATGATCAGTA GAATTGAATA TGTGCATACA 
AAGAATTTTA TACACAGAGA CATTAAACCA GATAACTTCC TAATGGGTAT TGGGCGTCAC 
TGTAATAAGT GTTTAGAATC TCCAGTGGGG AAGAGGAAAA GAAGCATGAC TGTTAGTACT 
TCTCAGGACC CATCTTTCTC AGGATTAAAC CAGTTATTCC TTATTGATTT TGGTTTGGCC 
AAAAAGTACA GAGACAACAG GACAAGGCAA CACATACCAT ACAGAGAAGA TAAAAACCTC 
ACTGGCACTG CCCGATATGC TAGCATCAAT GCACATCTTG GTATTGAGCA GAGTCGCCGA 
GATGACATGG AATCATTAGG ATATGTTTTG ATGTATTTTA ATAGAACCAG CCTGCCATGG 
CAAGGGCTAA AGGCTGCAAC AAAGAAACAA AAATATGAAA AGATTAGTGA AAAGAAGATG 
TCCACGCCTG TTGAAGTTTT ATGTAAGGGG TTTCCTGCAG AATTTGCGAT GTACTTAAAC 
TATTGTCGTG GGCTACGCTT TGAGGAAGCC CCAGATTACA TGTATCTGAG GCAGCTATTC 
CGCATTCTTT TCAGGACCCT GAACCATCAA TATGACTACA CATTTGATTG GACAATGTTA 
AAGCAGAAAG CAGCACAGCA GGCAGCCTCT TCCAGTGGGC AGGGTCAGCA GGCCCAAACC 
CCCACAGGCA AGCAAACTGA CAAAACCAAG AGTAACATGA AAGGTTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001271742.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258671.1 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu03880
Clone ID Related Accession (Same CDS sequence)	NM_001271742.1 , NM_001271742.2
Accession Version	NM_001271742.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021078.5, HY119498.1, AK293761.1, BC008717.2 and BU618830.1. On Jun 2, 2019 this sequence version replaced NM_001271742.1. Transcript Variant: This variant (4) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (4) with a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293761.1, SRR1660809.157032.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCTTC TGGGACCTAG CCTCGAAGAC CTCTTCAATT TCTGTTCAAG AAGGTTCACA 
ATGAAAACTG TACTTATGTT AGCTGACCAG ATGATCAGTA GAATTGAATA TGTGCATACA 
AAGAATTTTA TACACAGAGA CATTAAACCA GATAACTTCC TAATGGGTAT TGGGCGTCAC 
TGTAATAAGT GTTTAGAATC TCCAGTGGGG AAGAGGAAAA GAAGCATGAC TGTTAGTACT 
TCTCAGGACC CATCTTTCTC AGGATTAAAC CAGTTATTCC TTATTGATTT TGGTTTGGCC 
AAAAAGTACA GAGACAACAG GACAAGGCAA CACATACCAT ACAGAGAAGA TAAAAACCTC 
ACTGGCACTG CCCGATATGC TAGCATCAAT GCACATCTTG GTATTGAGCA GAGTCGCCGA 
GATGACATGG AATCATTAGG ATATGTTTTG ATGTATTTTA ATAGAACCAG CCTGCCATGG 
CAAGGGCTAA AGGCTGCAAC AAAGAAACAA AAATATGAAA AGATTAGTGA AAAGAAGATG 
TCCACGCCTG TTGAAGTTTT ATGTAAGGGG TTTCCTGCAG AATTTGCGAT GTACTTAAAC 
TATTGTCGTG GGCTACGCTT TGAGGAAGCC CCAGATTACA TGTATCTGAG GCAGCTATTC 
CGCATTCTTT TCAGGACCCT GAACCATCAA TATGACTACA CATTTGATTG GACAATGTTA 
AAGCAGAAAG CAGCACAGCA GGCAGCCTCT TCCAGTGGGC AGGGTCAGCA GGCCCAAACC 
CCCACAGGCA AGCAAACTGA CAAAACCAAG AGTAACATGA AAGGTTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258671.1
CDS	329..1159
Translation	MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF

Target ORF information:

RefSeq Version	NM_001271742.2
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271742.2

ORF Insert Sequence:

ATGGATCTTC TGGGACCTAG CCTCGAAGAC CTCTTCAATT TCTGTTCAAG AAGGTTCACA 
ATGAAAACTG TACTTATGTT AGCTGACCAG ATGATCAGTA GAATTGAATA TGTGCATACA 
AAGAATTTTA TACACAGAGA CATTAAACCA GATAACTTCC TAATGGGTAT TGGGCGTCAC 
TGTAATAAGT GTTTAGAATC TCCAGTGGGG AAGAGGAAAA GAAGCATGAC TGTTAGTACT 
TCTCAGGACC CATCTTTCTC AGGATTAAAC CAGTTATTCC TTATTGATTT TGGTTTGGCC 
AAAAAGTACA GAGACAACAG GACAAGGCAA CACATACCAT ACAGAGAAGA TAAAAACCTC 
ACTGGCACTG CCCGATATGC TAGCATCAAT GCACATCTTG GTATTGAGCA GAGTCGCCGA 
GATGACATGG AATCATTAGG ATATGTTTTG ATGTATTTTA ATAGAACCAG CCTGCCATGG 
CAAGGGCTAA AGGCTGCAAC AAAGAAACAA AAATATGAAA AGATTAGTGA AAAGAAGATG 
TCCACGCCTG TTGAAGTTTT ATGTAAGGGG TTTCCTGCAG AATTTGCGAT GTACTTAAAC 
TATTGTCGTG GGCTACGCTT TGAGGAAGCC CCAGATTACA TGTATCTGAG GCAGCTATTC 
CGCATTCTTT TCAGGACCCT GAACCATCAA TATGACTACA CATTTGATTG GACAATGTTA 
AAGCAGAAAG CAGCACAGCA GGCAGCCTCT TCCAGTGGGC AGGGTCAGCA GGCCCAAACC 
CCCACAGGCA AGCAAACTGA CAAAACCAAG AGTAACATGA AAGGTTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001025105.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020276.1 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10853
Clone ID Related Accession (Same CDS sequence)	NM_001025105.3 , NM_001025105.2
Accession Version	NM_001025105.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA144898.1, BC021971.2, DQ082865.1, AC021078.5, BC008717.2 and BU618830.1. On Jun 2, 2019 this sequence version replaced NM_001025105.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.209589.1, SRR1660805.257343.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTGTT TAGAATCTCC AGTGGGGAAG 
AGGAAAAGAA GCATGACTGT TAGTACTTCT CAGGACCCAT CTTTCTCAGG ATTAAACCAG 
TTATTCCTTA TTGATTTTGG TTTGGCCAAA AAGTACAGAG ACAACAGGAC AAGGCAACAC 
ATACCATACA GAGAAGATAA AAACCTCACT GGCACTGCCC GATATGCTAG CATCAATGCA 
CATCTTGGTA TTGAGCAGAG TCGCCGAGAT GACATGGAAT CATTAGGATA TGTTTTGATG 
TATTTTAATA GAACCAGCCT GCCATGGCAA GGGCTAAAGG CTGCAACAAA GAAACAAAAA 
TATGAAAAGA TTAGTGAAAA GAAGATGTCC ACGCCTGTTG AAGTTTTATG TAAGGGGTTT 
CCTGCAGAAT TTGCGATGTA CTTAAACTAT TGTCGTGGGC TACGCTTTGA GGAAGCCCCA 
GATTACATGT ATCTGAGGCA GCTATTCCGC ATTCTTTTCA GGACCCTGAA CCATCAATAT 
GACTACACAT TTGATTGGAC AATGTTAAAG CAGAAAGCAG CACAGCAGGC AGCCTCTTCC 
AGTGGGCAGG GTCAGCAGGC CCAAACCCCC ACAGGCAAGC AAACTGACAA AACCAAGAGT 
AACATGAAAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020276.1
CDS	476..1573
Translation	MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF

Target ORF information:

RefSeq Version	NM_001025105.3
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025105.3

ORF Insert Sequence:

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTGTT TAGAATCTCC AGTGGGGAAG 
AGGAAAAGAA GCATGACTGT TAGTACTTCT CAGGACCCAT CTTTCTCAGG ATTAAACCAG 
TTATTCCTTA TTGATTTTGG TTTGGCCAAA AAGTACAGAG ACAACAGGAC AAGGCAACAC 
ATACCATACA GAGAAGATAA AAACCTCACT GGCACTGCCC GATATGCTAG CATCAATGCA 
CATCTTGGTA TTGAGCAGAG TCGCCGAGAT GACATGGAAT CATTAGGATA TGTTTTGATG 
TATTTTAATA GAACCAGCCT GCCATGGCAA GGGCTAAAGG CTGCAACAAA GAAACAAAAA 
TATGAAAAGA TTAGTGAAAA GAAGATGTCC ACGCCTGTTG AAGTTTTATG TAAGGGGTTT 
CCTGCAGAAT TTGCGATGTA CTTAAACTAT TGTCGTGGGC TACGCTTTGA GGAAGCCCCA 
GATTACATGT ATCTGAGGCA GCTATTCCGC ATTCTTTTCA GGACCCTGAA CCATCAATAT 
GACTACACAT TTGATTGGAC AATGTTAAAG CAGAAAGCAG CACAGCAGGC AGCCTCTTCC 
AGTGGGCAGG GTCAGCAGGC CCAAACCCCC ACAGGCAAGC AAACTGACAA AACCAAGAGT 
AACATGAAAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSNK1A1 ( NM_001025105.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020276.1 Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10853
Clone ID Related Accession (Same CDS sequence)	NM_001025105.3 , NM_001025105.2
Accession Version	NM_001025105.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	casein kinase I isoform alpha isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA144898.1, BC021971.2, DQ082865.1, AC021078.5, BC008717.2 and BU618830.1. On Nov 14, 2012 this sequence version replaced NM_001025105.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.44960.1, SRR1660807.237050.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTGTT TAGAATCTCC AGTGGGGAAG 
AGGAAAAGAA GCATGACTGT TAGTACTTCT CAGGACCCAT CTTTCTCAGG ATTAAACCAG 
TTATTCCTTA TTGATTTTGG TTTGGCCAAA AAGTACAGAG ACAACAGGAC AAGGCAACAC 
ATACCATACA GAGAAGATAA AAACCTCACT GGCACTGCCC GATATGCTAG CATCAATGCA 
CATCTTGGTA TTGAGCAGAG TCGCCGAGAT GACATGGAAT CATTAGGATA TGTTTTGATG 
TATTTTAATA GAACCAGCCT GCCATGGCAA GGGCTAAAGG CTGCAACAAA GAAACAAAAA 
TATGAAAAGA TTAGTGAAAA GAAGATGTCC ACGCCTGTTG AAGTTTTATG TAAGGGGTTT 
CCTGCAGAAT TTGCGATGTA CTTAAACTAT TGTCGTGGGC TACGCTTTGA GGAAGCCCCA 
GATTACATGT ATCTGAGGCA GCTATTCCGC ATTCTTTTCA GGACCCTGAA CCATCAATAT 
GACTACACAT TTGATTGGAC AATGTTAAAG CAGAAAGCAG CACAGCAGGC AGCCTCTTCC 
AGTGGGCAGG GTCAGCAGGC CCAAACCCCC ACAGGCAAGC AAACTGACAA AACCAAGAGT 
AACATGAAAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020276.1
CDS	589..1686
Translation	MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF

Target ORF information:

RefSeq Version	NM_001025105.2
Organism	Homo sapiens(human)
Definition	Homo sapiens casein kinase 1 alpha 1 (CSNK1A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025105.2

ORF Insert Sequence:

ATGGCGAGTA GCAGCGGCTC CAAGGCTGAA TTCATTGTCG GAGGGAAATA TAAACTGGTA 
CGGAAGATCG GGTCTGGCTC CTTCGGGGAC ATCTATTTGG CGATCAACAT CACCAACGGC 
GAGGAAGTGG CAGTGAAGCT AGAATCTCAG AAGGCCAGGC ATCCCCAGTT GCTGTACGAG 
AGCAAGCTCT ATAAGATTCT TCAAGGTGGG GTTGGCATCC CCCACATACG GTGGTATGGT 
CAGGAAAAAG ACTACAATGT ACTAGTCATG GATCTTCTGG GACCTAGCCT CGAAGACCTC 
TTCAATTTCT GTTCAAGAAG GTTCACAATG AAAACTGTAC TTATGTTAGC TGACCAGATG 
ATCAGTAGAA TTGAATATGT GCATACAAAG AATTTTATAC ACAGAGACAT TAAACCAGAT 
AACTTCCTAA TGGGTATTGG GCGTCACTGT AATAAGTGTT TAGAATCTCC AGTGGGGAAG 
AGGAAAAGAA GCATGACTGT TAGTACTTCT CAGGACCCAT CTTTCTCAGG ATTAAACCAG 
TTATTCCTTA TTGATTTTGG TTTGGCCAAA AAGTACAGAG ACAACAGGAC AAGGCAACAC 
ATACCATACA GAGAAGATAA AAACCTCACT GGCACTGCCC GATATGCTAG CATCAATGCA 
CATCTTGGTA TTGAGCAGAG TCGCCGAGAT GACATGGAAT CATTAGGATA TGTTTTGATG 
TATTTTAATA GAACCAGCCT GCCATGGCAA GGGCTAAAGG CTGCAACAAA GAAACAAAAA 
TATGAAAAGA TTAGTGAAAA GAAGATGTCC ACGCCTGTTG AAGTTTTATG TAAGGGGTTT 
CCTGCAGAAT TTGCGATGTA CTTAAACTAT TGTCGTGGGC TACGCTTTGA GGAAGCCCCA 
GATTACATGT ATCTGAGGCA GCTATTCCGC ATTCTTTTCA GGACCCTGAA CCATCAATAT 
GACTACACAT TTGATTGGAC AATGTTAAAG CAGAAAGCAG CACAGCAGGC AGCCTCTTCC 
AGTGGGCAGG GTCAGCAGGC CCAAACCCCC ACAGGCAAGC AAACTGACAA AACCAAGAGT 
AACATGAAAG GTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Casein kinase 1? mediates degradation of receptors for type I and type II interferons caused by hemagglutinin of influenza A virus.
Journal of virology(2018 Jan)
Xia C,Wolf JJ,Vijayan M,Studstill CJ,Ma W,Hahm B

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CSNK1A1 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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