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GPR183 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol GPR183
Entrez Gene ID 1880
Full Name G protein-coupled receptor 183
Synonyms EBI2,hEBI2
General protein information
Preferred Names

G protein-coupled receptor 183

Names

G-protein coupled receptor 183
EBV-induced G-protein coupled receptor 2
Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)
epstein-Barr virus-induced G-protein coupled receptor 2

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

13

13q32.3

Summary This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown. [provided by RefSeq, Jul 2008].
Disorder MIM:

605741


mRNA and Protein(s)

mRNA Protein Name
XM_017020405.1 XP_016875894.1 G-protein coupled receptor 183 isoform X1
NM_004951.4 NP_004942.1 G-protein coupled receptor 183



Mus musculus (house mouse) Gpr183 NP_898852.2
Gallus gallus (chicken) GPR183 XP_001231944.1
Macaca mulatta (rhesus monkey) GPR183 XP_001091970.1
Danio rerio (zebrafish) gpr183 NP_001092711.1
Danio rerio (zebrafish) si:dkey-22o12.5 NP_001124284.1
Xenopus tropicalis (tropical clawed frog) LOC101731463 XP_004911877.1
Pan troglodytes (chimpanzee) GPR183 XP_001146657.1
Rattus norvegicus (Norway rat) Gpr183 NP_001102856.1
Homo sapiens (human) GPR183 NP_004942.1
Canis lupus familiaris (dog) GPR183 XP_005634101.1
Danio rerio (zebrafish) LOC100333319 XP_005160018.1


Related articles in PubMed

EBI2 regulates intracellular signaling and migration in human astrocyte.
Rutkowska A, Preuss I, Gessier F, Sailer AW, Dev KK
Glia63(2)341-51(2015 Feb)

Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor.
Gessier F, Preuss I, Yin H, Rosenkilde MM, Laurent S, Endres R, Chen YA, Marsilje TH, Seuwen K, Nguyen DG, Sailer AW
Journal of medicinal chemistry57(8)3358-68(2014 Apr)

Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages.
Preuss I, Ludwig MG, Baumgarten B, Bassilana F, Gessier F, Seuwen K, Sailer AW
Biochemical and biophysical research communications446(3)663-8(2014 Apr)

Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression.
Hulse KE, Norton JE, Suh L, Zhong Q, Mahdavinia M, Simon P, Kern RC, Conley DB, Chandra RK, Tan BK, Peters AT, Grammer LC 3rd, Harris KE, Carter RG, Kato A, Schleimer RP
The Journal of allergy and clinical immunology131(4)1075-83, 1083.e1-7(2013 Apr)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, , Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature491(7422)119-24(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

On ligand engagement, EBI2 typically signals via inhibitory G-protein subunit alpha to induce intracellular calcium mobilization, mitogen-activated protein kinase (MAPK) activation, and cell proliferation.
Title: Epstein-Barr Virus-induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways.

this study concludes that EBI2 expression is directly influenced by EBV infection and that BRRF1 is necessary and sufficient for EBI2 upregulation during infection.
Title: EBI2 expression in B lymphocytes is controlled by the Epstein-Barr virus transcription factor, BRRF1 (Na), during viral infection.

Human EBI2 (GPR183) expression in mice leads to an abnormally expanded CD5+ B1a B-cell subset and chronic lymphocytic leukemia-like B-cell malignancies.
Title: EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies.

Studies provide evidence that EBI2 and oxysterols are important players not only in the immune system but also in the central nervous system. Proper functioning of the EBI2/oxysterol system seems crucial for healthy physiology and prevention of the onset or progression of several neurodegenerative diseases. [review]
Title: The Role of the Oxysterol/EBI2 Pathway in the Immune and Central Nervous Systems.

These results demonstrate a role for EBI2 in astrocyte function and suggest that modulation of this receptor may be beneficial in neuroinflammatory disorders.
Title: EBI2 regulates intracellular signaling and migration in human astrocyte.

The following GPR183 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPR183 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu16498 NM_004951.4
Latest version!
Homo sapiens G protein-coupled receptor 183 (GPR183), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
OHu16498 XM_017020405.1
Latest version!
Homo sapiens G protein-coupled receptor 183 (GPR183), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16498
Clone ID Related Accession (Same CDS sequence) XM_017020405.1 , NM_004951.4
Accession Version NM_004951.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1086bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-04
Organism Homo sapiens(Human)
Product G-protein coupled receptor 183
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313443.1, BC020752.1 and AW574697.1. On Jul 26, 2008 this sequence version replaced NM_004951.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.323166.1, SRR1163655.99614.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149004, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

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ATGGATATAC AAATGGCAAA CAATTTTACT CCGCCCTCTG CAACTCCTCA GGGAAATGAC 
TGTGACCTCT ATGCACATCA CAGCACGGCC AGGATAGTAA TGCCTCTGCA TTACAGCCTC
GTCTTCATCA TTGGGCTCGT GGGAAACTTA CTAGCCTTGG TCGTCATTGT TCAAAACAGG
AAAAAAATCA ACTCTACCAC CCTCTATTCA ACAAATTTGG TGATTTCTGA TATACTTTTT
ACCACCGCTT TGCCTACACG AATAGCCTAC TATGCAATGG GCTTTGACTG GAGAATCGGA
GATGCCTTGT GTAGGATAAC TGCGCTAGTG TTTTACATCA ACACATATGC AGGTGTGAAC
TTTATGACCT GCCTGAGTAT TGACCGCTTC ATTGCTGTGG TGCACCCTCT ACGCTACAAC
AAGATAAAAA GGATTGAACA TGCAAAAGGC GTGTGCATAT TTGTCTGGAT TCTAGTATTT
GCTCAGACAC TCCCACTCCT CATCAACCCT ATGTCAAAGC AGGAGGCTGA AAGGATTACA
TGCATGGAGT ATCCAAACTT TGAAGAAACT AAATCTCTTC CCTGGATTCT GCTTGGGGCA
TGTTTCATAG GATATGTACT TCCACTTATA ATCATTCTCA TCTGCTATTC TCAGATCTGC
TGCAAACTCT TCAGAACTGC CAAACAAAAC CCACTCACTG AGAAATCTGG TGTAAACAAA
AAGGCTCTCA ACACAATTAT TCTTATTATT GTTGTGTTTG TTCTCTGTTT CACACCTTAC
CATGTTGCAA TTATTCAACA TATGATTAAG AAGCTTCGTT TCTCTAATTT CCTGGAATGT
AGCCAAAGAC ATTCGTTCCA GATTTCTCTG CACTTTACAG TATGCCTGAT GAACTTCAAT
TGCTGCATGG ACCCTTTTAT CTACTTCTTT GCATGTAAAG GGTATAAGAG AAAGGTTATG
AGGATGCTGA AACGGCAAGT CAGTGTATCG ATTTCTAGTG CTGTGAAGTC AGCCCCTGAA
GAAAATTCAC GTGAAATGAC AGAAACGCAG ATGATGATAC ATTCCAAGTC TTCAAATGGA
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004942.1
CDS175..1260
Misc Feature(1)151..153
Misc Feature(2)232..1173
Misc Feature(3)268..345
Misc Feature(4)301..>657
Misc Feature(5)406..459
Misc Feature(6)490..555
Misc Feature(7)550..576
Misc Feature(8)622..678
Misc Feature(9)751..819
Misc Feature(10)898..969
Misc Feature(11)1036..1110
Misc Feature(12)1156..1158
Exon (1)1..156
Exon (2)157..1785
Translation

Target ORF information:

RefSeq Version NM_004951.4
Organism Homo sapiens(Human)
Definition Homo sapiens G protein-coupled receptor 183 (GPR183), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004951.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGATATAC AAATGGCAAA CAATTTTACT CCGCCCTCTG CAACTCCTCA GGGAAATGAC 
TGTGACCTCT ATGCACATCA CAGCACGGCC AGGATAGTAA TGCCTCTGCA TTACAGCCTC
GTCTTCATCA TTGGGCTCGT GGGAAACTTA CTAGCCTTGG TCGTCATTGT TCAAAACAGG
AAAAAAATCA ACTCTACCAC CCTCTATTCA ACAAATTTGG TGATTTCTGA TATACTTTTT
ACCACCGCTT TGCCTACACG AATAGCCTAC TATGCAATGG GCTTTGACTG GAGAATCGGA
GATGCCTTGT GTAGGATAAC TGCGCTAGTG TTTTACATCA ACACATATGC AGGTGTGAAC
TTTATGACCT GCCTGAGTAT TGACCGCTTC ATTGCTGTGG TGCACCCTCT ACGCTACAAC
AAGATAAAAA GGATTGAACA TGCAAAAGGC GTGTGCATAT TTGTCTGGAT TCTAGTATTT
GCTCAGACAC TCCCACTCCT CATCAACCCT ATGTCAAAGC AGGAGGCTGA AAGGATTACA
TGCATGGAGT ATCCAAACTT TGAAGAAACT AAATCTCTTC CCTGGATTCT GCTTGGGGCA
TGTTTCATAG GATATGTACT TCCACTTATA ATCATTCTCA TCTGCTATTC TCAGATCTGC
TGCAAACTCT TCAGAACTGC CAAACAAAAC CCACTCACTG AGAAATCTGG TGTAAACAAA
AAGGCTCTCA ACACAATTAT TCTTATTATT GTTGTGTTTG TTCTCTGTTT CACACCTTAC
CATGTTGCAA TTATTCAACA TATGATTAAG AAGCTTCGTT TCTCTAATTT CCTGGAATGT
AGCCAAAGAC ATTCGTTCCA GATTTCTCTG CACTTTACAG TATGCCTGAT GAACTTCAAT
TGCTGCATGG ACCCTTTTAT CTACTTCTTT GCATGTAAAG GGTATAAGAG AAAGGTTATG
AGGATGCTGA AACGGCAAGT CAGTGTATCG ATTTCTAGTG CTGTGAAGTC AGCCCCTGAA
GAAAATTCAC GTGAAATGAC AGAAACGCAG ATGATGATAC ATTCCAAGTC TTCAAATGGA
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16498
Clone ID Related Accession (Same CDS sequence) XM_017020405.1 , NM_004951.4
Accession Version XM_017020405.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1086bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product G-protein coupled receptor 183 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGATATAC AAATGGCAAA CAATTTTACT CCGCCCTCTG CAACTCCTCA GGGAAATGAC 
TGTGACCTCT ATGCACATCA CAGCACGGCC AGGATAGTAA TGCCTCTGCA TTACAGCCTC
GTCTTCATCA TTGGGCTCGT GGGAAACTTA CTAGCCTTGG TCGTCATTGT TCAAAACAGG
AAAAAAATCA ACTCTACCAC CCTCTATTCA ACAAATTTGG TGATTTCTGA TATACTTTTT
ACCACCGCTT TGCCTACACG AATAGCCTAC TATGCAATGG GCTTTGACTG GAGAATCGGA
GATGCCTTGT GTAGGATAAC TGCGCTAGTG TTTTACATCA ACACATATGC AGGTGTGAAC
TTTATGACCT GCCTGAGTAT TGACCGCTTC ATTGCTGTGG TGCACCCTCT ACGCTACAAC
AAGATAAAAA GGATTGAACA TGCAAAAGGC GTGTGCATAT TTGTCTGGAT TCTAGTATTT
GCTCAGACAC TCCCACTCCT CATCAACCCT ATGTCAAAGC AGGAGGCTGA AAGGATTACA
TGCATGGAGT ATCCAAACTT TGAAGAAACT AAATCTCTTC CCTGGATTCT GCTTGGGGCA
TGTTTCATAG GATATGTACT TCCACTTATA ATCATTCTCA TCTGCTATTC TCAGATCTGC
TGCAAACTCT TCAGAACTGC CAAACAAAAC CCACTCACTG AGAAATCTGG TGTAAACAAA
AAGGCTCTCA ACACAATTAT TCTTATTATT GTTGTGTTTG TTCTCTGTTT CACACCTTAC
CATGTTGCAA TTATTCAACA TATGATTAAG AAGCTTCGTT TCTCTAATTT CCTGGAATGT
AGCCAAAGAC ATTCGTTCCA GATTTCTCTG CACTTTACAG TATGCCTGAT GAACTTCAAT
TGCTGCATGG ACCCTTTTAT CTACTTCTTT GCATGTAAAG GGTATAAGAG AAAGGTTATG
AGGATGCTGA AACGGCAAGT CAGTGTATCG ATTTCTAGTG CTGTGAAGTC AGCCCCTGAA
GAAAATTCAC GTGAAATGAC AGAAACGCAG ATGATGATAC ATTCCAAGTC TTCAAATGGA
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016875894.1
CDS118..1203
Misc Feature(1)175..1116
Misc Feature(2)244..>600
Translation

Target ORF information:

RefSeq Version XM_017020405.1
Organism Homo sapiens(Human)
Definition Homo sapiens G protein-coupled receptor 183 (GPR183), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017020405.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGATATAC AAATGGCAAA CAATTTTACT CCGCCCTCTG CAACTCCTCA GGGAAATGAC 
TGTGACCTCT ATGCACATCA CAGCACGGCC AGGATAGTAA TGCCTCTGCA TTACAGCCTC
GTCTTCATCA TTGGGCTCGT GGGAAACTTA CTAGCCTTGG TCGTCATTGT TCAAAACAGG
AAAAAAATCA ACTCTACCAC CCTCTATTCA ACAAATTTGG TGATTTCTGA TATACTTTTT
ACCACCGCTT TGCCTACACG AATAGCCTAC TATGCAATGG GCTTTGACTG GAGAATCGGA
GATGCCTTGT GTAGGATAAC TGCGCTAGTG TTTTACATCA ACACATATGC AGGTGTGAAC
TTTATGACCT GCCTGAGTAT TGACCGCTTC ATTGCTGTGG TGCACCCTCT ACGCTACAAC
AAGATAAAAA GGATTGAACA TGCAAAAGGC GTGTGCATAT TTGTCTGGAT TCTAGTATTT
GCTCAGACAC TCCCACTCCT CATCAACCCT ATGTCAAAGC AGGAGGCTGA AAGGATTACA
TGCATGGAGT ATCCAAACTT TGAAGAAACT AAATCTCTTC CCTGGATTCT GCTTGGGGCA
TGTTTCATAG GATATGTACT TCCACTTATA ATCATTCTCA TCTGCTATTC TCAGATCTGC
TGCAAACTCT TCAGAACTGC CAAACAAAAC CCACTCACTG AGAAATCTGG TGTAAACAAA
AAGGCTCTCA ACACAATTAT TCTTATTATT GTTGTGTTTG TTCTCTGTTT CACACCTTAC
CATGTTGCAA TTATTCAACA TATGATTAAG AAGCTTCGTT TCTCTAATTT CCTGGAATGT
AGCCAAAGAC ATTCGTTCCA GATTTCTCTG CACTTTACAG TATGCCTGAT GAACTTCAAT
TGCTGCATGG ACCCTTTTAT CTACTTCTTT GCATGTAAAG GGTATAAGAG AAAGGTTATG
AGGATGCTGA AACGGCAAGT CAGTGTATCG ATTTCTAGTG CTGTGAAGTC AGCCCCTGAA
GAAAATTCAC GTGAAATGAC AGAAACGCAG ATGATGATAC ATTCCAAGTC TTCAAATGGA
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

EBI2 regulates intracellular signaling and migration in human astrocyte.
Glia63(2)341-51(2015 Feb)
Rutkowska A,Preuss I,Gessier F,Sailer AW,Dev KK


book

Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor.
Journal of medicinal chemistry57(8)3358-68(2014 Apr)
Gessier F,Preuss I,Yin H,Rosenkilde MM,Laurent S,Endres R,Chen YA,Marsilje TH,Seuwen K,Nguyen DG,Sailer AW


book

Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages.
Biochemical and biophysical research communications446(3)663-8(2014 Apr)
Preuss I,Ludwig MG,Baumgarten B,Bassilana F,Gessier F,Seuwen K,Sailer AW


book

Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression.
The Journal of allergy and clinical immunology131(4)1075-83, 1083.e1-7(2013 Apr)
Hulse KE,Norton JE,Suh L,Zhong Q,Mahdavinia M,Simon P,Kern RC,Conley DB,Chandra RK,Tan BK,Peters AT,Grammer LC 3rd,Harris KE,Carter RG,Kato A,Schleimer RP


book

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature491(7422)119-24(2012 Nov)
Jostins L,Ripke S,Weersma RK,Duerr RH,McGovern DP,Hui KY,Lee JC,Schumm LP,Sharma Y,Anderson CA,Essers J,Mitrovic M,Ning K,Cleynen I,Theatre E,Spain SL,Raychaudhuri S,Goyette P,Wei Z,Abraham C,Achkar JP,Ahmad T,Amininejad L,Ananthakrishnan AN,Andersen V,Andrews JM,Baidoo L,Balschun T,Bampton PA,Bitton A,Boucher G,Brand S,Büning C,Cohain A,Cichon S,D'Amato M,De Jong D,Devaney KL,Dubinsky M,Edwards C,Ellinghaus D,Ferguson LR,Franchimont D,Fransen K,Gearry R,Georges M,Gieger C,Glas J,Haritunians T,Hart A,Hawkey C,Hedl M,Hu X,Karlsen TH,Kupcinskas L,Kugathasan S,Latiano A,Laukens D,Lawrance IC,Lees CW,Louis E,Mahy G,Mansfield J,Morgan AR,Mowat C,Newman W,Palmieri O,Ponsioen CY,Potocnik U,Prescott NJ,Regueiro M,Rotter JI,Russell RK,Sanderson JD,Sans M,Satsangi J,Schreiber S,Simms LA,Sventoraityte J,Targan SR,Taylor KD,Tremelling M,Verspaget HW,De Vos M,Wijmenga C,Wilson DC,Winkelmann J,Xavier RJ,Zeissig S,Zhang B,Zhang CK,Zhao H,,Silverberg MS,Annese V,Hakonarson H,Brant SR,Radford-Smith G,Mathew CG,Rioux JD,Schadt EE,Daly MJ,Franke A,Parkes M,Vermeire S,Barrett JC,Cho JH


 
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