ARL5B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ARL5B
Entrez Gene ID	221079
Full Name	ADP ribosylation factor like GTPase 5B
Synonyms	ARL8
General protein information	Preferred Names ADP ribosylation factor like GTPase 5B Names ADP-ribosylation factor-like protein 5B ADP-ribosylation factor-like 5B ADP-ribosylation factor-like 8 ADP-ribosylation factor-like protein 8 ADP-ribosylation-like factor 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p12.31
Summary	ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010].
Disorder MIM:	608909

mRNA and Protein(s)

mRNA	Protein	Name
XM_005252400.1	XP_005252457.1	ADP-ribosylation factor-like protein 5B isoform X1
NM_178815.3	NP_848930.1	ADP-ribosylation factor-like protein 5B
NM_178815.4	NP_848930.1	ADP-ribosylation factor-like protein 5B
XM_005252401.4	XP_005252458.1	ADP-ribosylation factor-like protein 5B isoform X2
NM_178815.5	NP_848930.1	ADP-ribosylation factor-like protein 5B

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ARL5B	XP_005214350.1
Pan troglodytes (chimpanzee)	ARL5B	XP_001154062.1
	ARL5B	XP_001094437.2
Mus musculus (house mouse)	Arl5b	NP_083742.2
Danio rerio (zebrafish)	arl8	NP_956118.1
Homo sapiens (human)	ARL5B	NP_848930.1
Canis lupus familiaris (dog)	ARL5B	XP_005617141.1
Xenopus tropicalis (tropical clawed frog)	arl5a	NP_001006744.1
Gallus gallus (chicken)	ARL5B	NP_001137441.1

Gene Ontology
Bibliography

Related articles in PubMed

Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.
Toh WH, Tan JZ, Zulkefli KL, Houghton FJ, Gleeson PA
Traffic (Copenhagen, Denmark)18(3)159-175(2017 03)

The small G protein Arl5 contributes to endosome-to-Golgi traffic by aiding the recruitment of the GARP complex to the Golgi.
Rosa-Ferreira C, Christis C, Torres IL, Munro S
Biology open4(4)474-81(2015 Mar)

Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport.
Houghton FJ, Bellingham SA, Hill AF, Bourges D, Ang DK, Gemetzis T, Gasnereau I, Gleeson PA
Experimental cell research318(5)464-77(2012 Mar)

Arl8 and SKIP act together to link lysosomes to kinesin-1.
Rosa-Ferreira C, Munro S
Developmental cell21(6)1171-8(2011 Dec)

GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
Aouizerat BE, Vittinghoff E, Musone SL, Pawlikowska L, Kwok PY, Olgin JE, Tseng ZH
BMC cardiovascular disorders1129(2011 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Depletion of either Arl5b or AP4 results in the accumulation of APP.
Title: Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.

Arl5b is a trans-golgi-network-localised small G protein that plays a key role in regulating transport along the endosome-trans-golgi network pathway
Title: Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport.

Arl8 and SKIP are required for lysosomes to distribute away from the microtubule-organizing center. We identify two kinesin light chain binding motifs in SKIP that are required for lysosomes to accumulate kinesin-1 and redistribute to the cell periphery.
Title: Arl8 and SKIP act together to link lysosomes to kinesin-1.

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Genome-wide association reveals genetic effects on human A?42 and ? protein levels in cerebrospinal fluids: a case control study.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following ARL5B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARL5B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07537	NM_178815.5 Latest version!	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu43698	XM_005252401.4 Latest version!	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu43697	XM_005252400.1 Latest version!	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu07537	NM_178815.3	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu07537	NM_178815.4	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARL5B ( NM_178815.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_848930.1 Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.

Price & Availability↑

CloneID	OHu07537
Clone ID Related Accession (Same CDS sequence)	NM_178815.3 , NM_178815.4 , NM_178815.5
Accession Version	NM_178815.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-26
Organism	Homo sapiens(Human)
Product	ADP-ribosylation factor-like protein 5B
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN301486.1, BC024163.1, AK027275.1, AF494061.1 and AL700452.1. On Feb 16, 2005 this sequence version replaced NM_178815.2. ##Evidence-Data-START## Transcript exon combination :: BC024163.1, SRR1660807.260480.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGTTCAT CATTCTTGTT GTTGATAGCA TTGACAGGGA ACGACTAGCT 
ATTACAAAAG AAGAATTATA CAGAATGTTG GCTCATGAGG ATTTACGGAA GGCTGCAGTC 
CTTATCTTTG CAAATAAACA GGATATGAAA GGGTGTATGA CAGCAGCTGA AATCTCGAAA 
TACCTCACCC TTAGTTCAAT TAAGGATCAT CCATGGCACA TTCAATCCTG CTGTGCTCTC 
ACAGGAGAAG GGTTATGCCA AGGTCTAGAG TGGATGACCT CCCGGATTGG TGTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848930.1
CDS	255..794
Translation	MGLIFAKLWSLFCNQEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEIVVKNTHFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAVLIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR

Target ORF information:

RefSeq Version	NM_178815.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178815.3

ORF Insert Sequence:

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGTTCAT CATTCTTGTT GTTGATAGCA TTGACAGGGA ACGACTAGCT 
ATTACAAAAG AAGAATTATA CAGAATGTTG GCTCATGAGG ATTTACGGAA GGCTGCAGTC 
CTTATCTTTG CAAATAAACA GGATATGAAA GGGTGTATGA CAGCAGCTGA AATCTCGAAA 
TACCTCACCC TTAGTTCAAT TAAGGATCAT CCATGGCACA TTCAATCCTG CTGTGCTCTC 
ACAGGAGAAG GGTTATGCCA AGGTCTAGAG TGGATGACCT CCCGGATTGG TGTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARL5B ( NM_178815.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_848930.1 Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.

Price & Availability↑

CloneID	OHu07537
Clone ID Related Accession (Same CDS sequence)	NM_178815.3 , NM_178815.4 , NM_178815.5
Accession Version	NM_178815.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-17
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-like protein 5B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL512641.9 and AL133611.1. On Aug 29, 2017 this sequence version replaced NM_178815.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.260480.1, SRR1803612.82863.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGTTCAT CATTCTTGTT GTTGATAGCA TTGACAGGGA ACGACTAGCT 
ATTACAAAAG AAGAATTATA CAGAATGTTG GCTCATGAGG ATTTACGGAA GGCTGCAGTC 
CTTATCTTTG CAAATAAACA GGATATGAAA GGGTGTATGA CAGCAGCTGA AATCTCGAAA 
TACCTCACCC TTAGTTCAAT TAAGGATCAT CCATGGCACA TTCAATCCTG CTGTGCTCTC 
ACAGGAGAAG GGTTATGCCA AGGTCTAGAG TGGATGACCT CCCGGATTGG TGTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848930.1
CDS	304..843
Translation	MGLIFAKLWSLFCNQEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEIVVKNTHFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAVLIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR

Target ORF information:

RefSeq Version	NM_178815.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178815.4

ORF Insert Sequence:

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGTTCAT CATTCTTGTT GTTGATAGCA TTGACAGGGA ACGACTAGCT 
ATTACAAAAG AAGAATTATA CAGAATGTTG GCTCATGAGG ATTTACGGAA GGCTGCAGTC 
CTTATCTTTG CAAATAAACA GGATATGAAA GGGTGTATGA CAGCAGCTGA AATCTCGAAA 
TACCTCACCC TTAGTTCAAT TAAGGATCAT CCATGGCACA TTCAATCCTG CTGTGCTCTC 
ACAGGAGAAG GGTTATGCCA AGGTCTAGAG TGGATGACCT CCCGGATTGG TGTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARL5B ( NM_178815.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_848930.1 Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.

Price & Availability↑

CloneID	OHu07537
Clone ID Related Accession (Same CDS sequence)	NM_178815.3 , NM_178815.4 , NM_178815.5
Accession Version	NM_178815.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-like protein 5B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL512641.9 and AL133611.1. On Nov 22, 2018 this sequence version replaced NM_178815.4. ##Evidence-Data-START## Transcript exon combination :: AK027275.1, SRR1660803.160272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377275.4/ ENSP00000366487.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGTTCAT CATTCTTGTT GTTGATAGCA TTGACAGGGA ACGACTAGCT 
ATTACAAAAG AAGAATTATA CAGAATGTTG GCTCATGAGG ATTTACGGAA GGCTGCAGTC 
CTTATCTTTG CAAATAAACA GGATATGAAA GGGTGTATGA CAGCAGCTGA AATCTCGAAA 
TACCTCACCC TTAGTTCAAT TAAGGATCAT CCATGGCACA TTCAATCCTG CTGTGCTCTC 
ACAGGAGAAG GGTTATGCCA AGGTCTAGAG TGGATGACCT CCCGGATTGG TGTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848930.1
CDS	208..747
Translation	MGLIFAKLWSLFCNQEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEIVVKNTHFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAVLIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR

Target ORF information:

RefSeq Version	NM_178815.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178815.5

ORF Insert Sequence:

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGTTCAT CATTCTTGTT GTTGATAGCA TTGACAGGGA ACGACTAGCT 
ATTACAAAAG AAGAATTATA CAGAATGTTG GCTCATGAGG ATTTACGGAA GGCTGCAGTC 
CTTATCTTTG CAAATAAACA GGATATGAAA GGGTGTATGA CAGCAGCTGA AATCTCGAAA 
TACCTCACCC TTAGTTCAAT TAAGGATCAT CCATGGCACA TTCAATCCTG CTGTGCTCTC 
ACAGGAGAAG GGTTATGCCA AGGTCTAGAG TGGATGACCT CCCGGATTGG TGTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARL5B ( XM_005252401.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005252458.1 Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu43698
Clone ID Related Accession (Same CDS sequence)	XM_005252401.4
Accession Version	XM_005252401.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-like protein 5B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005252401.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGAAG TGGTTCATAC TTCTCCAACC ATAGGAAGCA ATGTTGAAGA AATAGTTGTG 
AAGAACACTC ATTTTCTTAT GTGGGATATT GGTGGTCAGG AGTCTCTGCG ATCATCCTGG 
AACACATATT ACTCAAATAC AGAGTTCATC ATTCTTGTTG TTGATAGCAT TGACAGGGAA 
CGACTAGCTA TTACAAAAGA AGAATTATAC AGAATGTTGG CTCATGAGGA TTTACGGAAG 
GCTGCAGTCC TTATCTTTGC AAATAAACAG GATATGAAAG GGTGTATGAC AGCAGCTGAA 
ATCTCGAAAT ACCTCACCCT TAGTTCAATT AAGGATCATC CATGGCACAT TCAATCCTGC 
TGTGCTCTCA CAGGAGAAGG GTTATGCCAA GGTCTAGAGT GGATGACCTC CCGGATTGGT 
GTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005252458.1
CDS	231..659
Translation	MNEVVHTSPTIGSNVEEIVVKNTHFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAVLIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR

Target ORF information:

RefSeq Version	XM_005252401.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005252401.4

ORF Insert Sequence:

ATGAATGAAG TGGTTCATAC TTCTCCAACC ATAGGAAGCA ATGTTGAAGA AATAGTTGTG 
AAGAACACTC ATTTTCTTAT GTGGGATATT GGTGGTCAGG AGTCTCTGCG ATCATCCTGG 
AACACATATT ACTCAAATAC AGAGTTCATC ATTCTTGTTG TTGATAGCAT TGACAGGGAA 
CGACTAGCTA TTACAAAAGA AGAATTATAC AGAATGTTGG CTCATGAGGA TTTACGGAAG 
GCTGCAGTCC TTATCTTTGC AAATAAACAG GATATGAAAG GGTGTATGAC AGCAGCTGAA 
ATCTCGAAAT ACCTCACCCT TAGTTCAATT AAGGATCATC CATGGCACAT TCAATCCTGC 
TGTGCTCTCA CAGGAGAAGG GTTATGCCAA GGTCTAGAGT GGATGACCTC CCGGATTGGT 
GTGAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARL5B ( XM_005252400.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005252457.1 Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43697
Clone ID Related Accession (Same CDS sequence)	XM_005252400.1
Accession Version	XM_005252400.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-like protein 5B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGGATTT ACGGAAGGCT GCAGTCCTTA TCTTTGCAAA TAAACAGGAT 
ATGAAAGGGT GTATGACAGC AGCTGAAATC TCGAAATACC TCACCCTTAG TTCAATTAAG 
GATCATCCAT GGCACATTCA ATCCTGCTGT GCTCTCACAG GAGAAGGGTT ATGCCAAGGT 
CTAGAGTGGA TGACCTCCCG GATTGGTGTG AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005252457.1
CDS	304..759
Translation	MGLIFAKLWSLFCNQEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEIVVKNTHFLMWDIGGQESLRSSWNTYYSNTEDLRKAAVLIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR

Target ORF information:

RefSeq Version	XM_005252400.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADP ribosylation factor like GTPase 5B (ARL5B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005252400.1

ORF Insert Sequence:

ATGGGGCTGA TCTTCGCCAA ACTGTGGAGC CTCTTCTGTA ACCAAGAACA CAAAGTAATT 
ATAGTGGGAC TGGATAATGC AGGGAAAACC ACCATTCTTT ACCAATTCTT AATGAATGAA 
GTGGTTCATA CTTCTCCAAC CATAGGAAGC AATGTTGAAG AAATAGTTGT GAAGAACACT 
CATTTTCTTA TGTGGGATAT TGGTGGTCAG GAGTCTCTGC GATCATCCTG GAACACATAT 
TACTCAAATA CAGAGGATTT ACGGAAGGCT GCAGTCCTTA TCTTTGCAAA TAAACAGGAT 
ATGAAAGGGT GTATGACAGC AGCTGAAATC TCGAAATACC TCACCCTTAG TTCAATTAAG 
GATCATCCAT GGCACATTCA ATCCTGCTGT GCTCTCACAG GAGAAGGGTT ATGCCAAGGT 
CTAGAGTGGA TGACCTCCCG GATTGGTGTG AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.
Traffic (Copenhagen, Denmark)18(3)159-175(2017 03)
Toh WH,Tan JZ,Zulkefli KL,Houghton FJ,Gleeson PA

The small G protein Arl5 contributes to endosome-to-Golgi traffic by aiding the recruitment of the GARP complex to the Golgi.
Biology open4(4)474-81(2015 Mar)
Rosa-Ferreira C,Christis C,Torres IL,Munro S

Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport.
Experimental cell research318(5)464-77(2012 Mar)
Houghton FJ,Bellingham SA,Hill AF,Bourges D,Ang DK,Gemetzis T,Gasnereau I,Gleeson PA

Arl8 and SKIP act together to link lysosomes to kinesin-1.
Developmental cell21(6)1171-8(2011 Dec)
Rosa-Ferreira C,Munro S

GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
BMC cardiovascular disorders1129(2011 Jun)
Aouizerat BE,Vittinghoff E,Musone SL,Pawlikowska L,Kwok PY,Olgin JE,Tseng ZH

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ARL5B cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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