GIMAP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GIMAP2
Entrez Gene ID	26157
Full Name	GTPase, IMAP family member 2
Synonyms	HIMAP2,IAN12,IMAP2
General protein information	Preferred Names GTPase, IMAP family member 2 Names GTPase IMAP family member 2 immune-associated nucleotide-binding protein 12 immunity associated protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q36.1
Summary	This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008].
Disorder MIM:	608085

mRNA and Protein(s)

mRNA	Protein	Name
NM_015660.3	NP_056475.1	GTPase IMAP family member 2
NM_015660.2	NP_056475.1	GTPase IMAP family member 2

Pathways from BioSystems

Homologies

	GIMAP2	XP_001102819.1
Homo sapiens (human)	GIMAP2	NP_056475.1
Canis lupus familiaris (dog)	GIMAP2	XP_003432107.1
Pan troglodytes (chimpanzee)	GIMAP2	XP_519529.3
Bos taurus (cattle)	GIMAP2	XP_003586076.2

Gene Ontology
Bibliography

Related articles in PubMed

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel D, Arasu BS, Marino SF, Lamprecht B, K?chert K, Rosenbaum E, Eichhorst J, Wiesner B, Behlke J, Rocks O, Mathas S, Daumke O
Structure (London, England : 1993)21(4)550-9(2013 Apr)

Genome-wide association study of smoking behaviours in patients with COPD.
Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK, ,
Thorax66(10)894-902(2011 Oct)

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel D, Fr?hlich C, Eichhorst J, Wiesner B, Behlke J, Aravind L, Daumke O
Proceedings of the National Academy of Sciences of the United States of America107(47)20299-304(2010 Nov)

Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Schwefel D, Fr?hlich C, Daumke O
Acta crystallographica. Section F, Structural biology and crystallization communications66(Pt 6)725-9(2010 Jun)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GDP-bound GIMAP2(21-260) and GDP-bound GIMAP2(1-234) crystallized in space group P2(1)2(1)2(1) and the crystals diffracted X-rays to 2.9 and 1.7 A resolution, respectively.
Title: Purification, crystallization and preliminary X-ray analysis of human GIMAP2.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

The following GIMAP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GIMAP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15451	NM_015660.3 Latest version!	Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu15451	NM_015660.2	Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GIMAP2 ( NM_015660.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056475.1 Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.

Price & Availability↑

CloneID	OHu15451
Clone ID Related Accession (Same CDS sequence)	NM_015660.3 , NM_015660.2
Accession Version	NM_015660.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG687383.1 and BC032345.1. On Nov 22, 2018 this sequence version replaced NM_015660.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.375681.1, SRR1163655.551100.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000223293.10/ ENSP00000223293.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACCAAA ATGAACACAG TCACTGGGGA CCACATGCAA AGGGCCAATG TGCCAGCAGA 
TCTGAGCTGA GAATCATCCT GGTGGGCAAA ACAGGAACTG GCAAAAGTGC TGCAGGGAAC 
AGCATCCTCA GGAAGCAAGC ATTTGAATCG AAGCTGGGTT CCCAGACCTT GACTAAGACT 
TGCAGCAAAA GTCAGGGAAG CTGGGGAAAT AGAGAGATTG TCATTATTGA CACACCAGAT 
ATGTTTTCTT GGAAGGACCA CTGTGAAGCT CTGTACAAAG AGGTGCAGAG GTGCTACTTG 
CTGTCTGCAC CAGGACCCCA TGTGCTGCTC CTGGTGACTC AGCTGGGCCG CTATACCTCA 
CAGGACCAGC AGGCTGCACA GAGGGTGAAG GAGATCTTTG GAGAGGATGC CATGGGACAC 
ACAATTGTCC TCTTTACCCA CAAGGAAGAC CTCAATGGTG GCTCCCTGAT GGATTACATG 
CACGACTCAG ATAACAAAGC CCTAAGCAAG CTGGTGGCAG CATGTGGTGG GCGAATCTGT 
GCCTTTAATA ACCGTGCTGA AGGGAGCAAT CAGGATGACC AAGTGAAGGA ACTAATGGAC 
TGTATTGAGG ATCTGTTGAT GGAGAAAAAT GGTGATCACT ATACCAATGG GTTGTACAGC 
CTAATACAGA GGTCTAAATG TGGACCTGTG GGATCAGATG AAAGAGTAAA GGAATTCAAA 
CAGAGCCTTA TAAAGTACAT GGAAACTCAA AGAAGTTACA CAGCCTTGGC TGAAGCAAAC 
TGCCTAAAAG GAGCCTTAAT CAAAACACAA CTGTGTGTTT TATTTTGTAT TCAGTTGTTT 
CTCAGATTGA TAATTCTGTG GCTTTGCATA CTGCACAGCA TGTGCAATTT GTTTTGTTGC 
TTACTCTTTA GTATGTGCAA TTTATTCTGC AGTTTGCTGT TTATTATACC CAAAAAGTTA 
ATGATATTTT TGAGAACAGT TATTAGACTA GAACGCAAGA CTCCTAGGTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056475.1
CDS	89..1102
Translation	MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCCLLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL

Target ORF information:

RefSeq Version	NM_015660.3
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015660.3

ORF Insert Sequence:

ATGGACCAAA ATGAACACAG TCACTGGGGA CCACATGCAA AGGGCCAATG TGCCAGCAGA 
TCTGAGCTGA GAATCATCCT GGTGGGCAAA ACAGGAACTG GCAAAAGTGC TGCAGGGAAC 
AGCATCCTCA GGAAGCAAGC ATTTGAATCG AAGCTGGGTT CCCAGACCTT GACTAAGACT 
TGCAGCAAAA GTCAGGGAAG CTGGGGAAAT AGAGAGATTG TCATTATTGA CACACCAGAT 
ATGTTTTCTT GGAAGGACCA CTGTGAAGCT CTGTACAAAG AGGTGCAGAG GTGCTACTTG 
CTGTCTGCAC CAGGACCCCA TGTGCTGCTC CTGGTGACTC AGCTGGGCCG CTATACCTCA 
CAGGACCAGC AGGCTGCACA GAGGGTGAAG GAGATCTTTG GAGAGGATGC CATGGGACAC 
ACAATTGTCC TCTTTACCCA CAAGGAAGAC CTCAATGGTG GCTCCCTGAT GGATTACATG 
CACGACTCAG ATAACAAAGC CCTAAGCAAG CTGGTGGCAG CATGTGGTGG GCGAATCTGT 
GCCTTTAATA ACCGTGCTGA AGGGAGCAAT CAGGATGACC AAGTGAAGGA ACTAATGGAC 
TGTATTGAGG ATCTGTTGAT GGAGAAAAAT GGTGATCACT ATACCAATGG GTTGTACAGC 
CTAATACAGA GGTCTAAATG TGGACCTGTG GGATCAGATG AAAGAGTAAA GGAATTCAAA 
CAGAGCCTTA TAAAGTACAT GGAAACTCAA AGAAGTTACA CAGCCTTGGC TGAAGCAAAC 
TGCCTAAAAG GAGCCTTAAT CAAAACACAA CTGTGTGTTT TATTTTGTAT TCAGTTGTTT 
CTCAGATTGA TAATTCTGTG GCTTTGCATA CTGCACAGCA TGTGCAATTT GTTTTGTTGC 
TTACTCTTTA GTATGTGCAA TTTATTCTGC AGTTTGCTGT TTATTATACC CAAAAAGTTA 
ATGATATTTT TGAGAACAGT TATTAGACTA GAACGCAAGA CTCCTAGGTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GIMAP2 ( NM_015660.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056475.1 Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.

Price & Availability↑

CloneID	OHu15451
Clone ID Related Accession (Same CDS sequence)	NM_015660.3 , NM_015660.2
Accession Version	NM_015660.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG687383.1 and BC032345.1. On Nov 16, 2004 this sequence version replaced NM_015660.1. ##Evidence-Data-START## Transcript exon combination :: ERR279836.8280.1, ERR279847.2005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCAAA ATGAACACAG TCACTGGGGA CCACATGCAA AGGGCCAATG TGCCAGCAGA 
TCTGAGCTGA GAATCATCCT GGTGGGCAAA ACAGGAACTG GCAAAAGTGC TGCAGGGAAC 
AGCATCCTCA GGAAGCAAGC ATTTGAATCG AAGCTGGGTT CCCAGACCTT GACTAAGACT 
TGCAGCAAAA GTCAGGGAAG CTGGGGAAAT AGAGAGATTG TCATTATTGA CACACCAGAT 
ATGTTTTCTT GGAAGGACCA CTGTGAAGCT CTGTACAAAG AGGTGCAGAG GTGCTACTTG 
CTGTCTGCAC CAGGACCCCA TGTGCTGCTC CTGGTGACTC AGCTGGGCCG CTATACCTCA 
CAGGACCAGC AGGCTGCACA GAGGGTGAAG GAGATCTTTG GAGAGGATGC CATGGGACAC 
ACAATTGTCC TCTTTACCCA CAAGGAAGAC CTCAATGGTG GCTCCCTGAT GGATTACATG 
CACGACTCAG ATAACAAAGC CCTAAGCAAG CTGGTGGCAG CATGTGGTGG GCGAATCTGT 
GCCTTTAATA ACCGTGCTGA AGGGAGCAAT CAGGATGACC AAGTGAAGGA ACTAATGGAC 
TGTATTGAGG ATCTGTTGAT GGAGAAAAAT GGTGATCACT ATACCAATGG GTTGTACAGC 
CTAATACAGA GGTCTAAATG TGGACCTGTG GGATCAGATG AAAGAGTAAA GGAATTCAAA 
CAGAGCCTTA TAAAGTACAT GGAAACTCAA AGAAGTTACA CAGCCTTGGC TGAAGCAAAC 
TGCCTAAAAG GAGCCTTAAT CAAAACACAA CTGTGTGTTT TATTTTGTAT TCAGTTGTTT 
CTCAGATTGA TAATTCTGTG GCTTTGCATA CTGCACAGCA TGTGCAATTT GTTTTGTTGC 
TTACTCTTTA GTATGTGCAA TTTATTCTGC AGTTTGCTGT TTATTATACC CAAAAAGTTA 
ATGATATTTT TGAGAACAGT TATTAGACTA GAACGCAAGA CTCCTAGGTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056475.1
CDS	89..1102
Translation	MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCCLLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL

Target ORF information:

RefSeq Version	NM_015660.2
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015660.2

ORF Insert Sequence:

ATGGACCAAA ATGAACACAG TCACTGGGGA CCACATGCAA AGGGCCAATG TGCCAGCAGA 
TCTGAGCTGA GAATCATCCT GGTGGGCAAA ACAGGAACTG GCAAAAGTGC TGCAGGGAAC 
AGCATCCTCA GGAAGCAAGC ATTTGAATCG AAGCTGGGTT CCCAGACCTT GACTAAGACT 
TGCAGCAAAA GTCAGGGAAG CTGGGGAAAT AGAGAGATTG TCATTATTGA CACACCAGAT 
ATGTTTTCTT GGAAGGACCA CTGTGAAGCT CTGTACAAAG AGGTGCAGAG GTGCTACTTG 
CTGTCTGCAC CAGGACCCCA TGTGCTGCTC CTGGTGACTC AGCTGGGCCG CTATACCTCA 
CAGGACCAGC AGGCTGCACA GAGGGTGAAG GAGATCTTTG GAGAGGATGC CATGGGACAC 
ACAATTGTCC TCTTTACCCA CAAGGAAGAC CTCAATGGTG GCTCCCTGAT GGATTACATG 
CACGACTCAG ATAACAAAGC CCTAAGCAAG CTGGTGGCAG CATGTGGTGG GCGAATCTGT 
GCCTTTAATA ACCGTGCTGA AGGGAGCAAT CAGGATGACC AAGTGAAGGA ACTAATGGAC 
TGTATTGAGG ATCTGTTGAT GGAGAAAAAT GGTGATCACT ATACCAATGG GTTGTACAGC 
CTAATACAGA GGTCTAAATG TGGACCTGTG GGATCAGATG AAAGAGTAAA GGAATTCAAA 
CAGAGCCTTA TAAAGTACAT GGAAACTCAA AGAAGTTACA CAGCCTTGGC TGAAGCAAAC 
TGCCTAAAAG GAGCCTTAAT CAAAACACAA CTGTGTGTTT TATTTTGTAT TCAGTTGTTT 
CTCAGATTGA TAATTCTGTG GCTTTGCATA CTGCACAGCA TGTGCAATTT GTTTTGTTGC 
TTACTCTTTA GTATGTGCAA TTTATTCTGC AGTTTGCTGT TTATTATACC CAAAAAGTTA 
ATGATATTTT TGAGAACAGT TATTAGACTA GAACGCAAGA CTCCTAGGTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Structure (London, England : 1993)21(4)550-9(2013 Apr)
Schwefel D,Arasu BS,Marino SF,Lamprecht B,K?chert K,Rosenbaum E,Eichhorst J,Wiesner B,Behlke J,Rocks O,Mathas S,Daumke O

Genome-wide association study of smoking behaviours in patients with COPD.
Thorax66(10)894-902(2011 Oct)
Siedlinski M,Cho MH,Bakke P,Gulsvik A,Lomas DA,Anderson W,Kong X,Rennard SI,Beaty TH,Hokanson JE,Crapo JD,Silverman EK,,

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Proceedings of the National Academy of Sciences of the United States of America107(47)20299-304(2010 Nov)
Schwefel D,Fr?hlich C,Eichhorst J,Wiesner B,Behlke J,Aravind L,Daumke O

Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Acta crystallographica. Section F, Structural biology and crystallization communications66(Pt 6)725-9(2010 Jun)
Schwefel D,Fr?hlich C,Daumke O

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

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GIMAP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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