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APOA1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol APOA1
Entrez Gene ID 335
Full Name apolipoprotein A-I
General protein information
Preferred Names
apolipoprotein A-I
Names
apolipoprotein A-I
apo-AI
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q23-q24

Summary This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

107680

Disorder Html: ApoA-I and apoC-III deficiency, combined (3);

mRNA and Protein(s)

mRNA Protein Name
XM_005271539 XP_005271596 apolipoprotein A-I isoform X1
XM_005271540 XP_005271597 apolipoprotein A-I isoform X1
NM_000039 NP_000030 apolipoprotein A-I preproprotein



Homo sapiens (human) APOA1 NP_000030.1
Pan troglodytes (chimpanzee) APOA1 XP_001153383.1
Macaca mulatta (Rhesus monkey) APOA1 XP_001090774.1
Canis lupus familiaris (dog) APOA1 XP_536564.2
Bos taurus (cattle) APOA1 NP_776667.2
Mus musculus (house mouse) Apoa1 NP_033822.2
Rattus norvegicus (Norway rat) Apoa1 NP_036870.1
Gallus gallus (chicken) APOA1 NP_990856.1
Danio rerio (zebrafish) apoa1a NP_571203.1
Danio rerio (zebrafish) apoa1b NP_001093614.2
Xenopus (Silurana) tropicalis (western clawed frog) apoa1 NP_001005127.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following APOA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APOA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu27099
XM_005271539 PREDICTED: Homo sapiens apolipoprotein A-I (APOA1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu27099
XM_005271540 PREDICTED: Homo sapiens apolipoprotein A-I (APOA1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu27099
NM_000039 Homo sapiens apolipoprotein A-I (APOA1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu27099
Clone ID Related Accession (Same CDS sequence) NM_000039 , XM_005271539 , XM_005271540
Accession Version XM_005271539.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 804bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product apolipoprotein A-I isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_033899.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530398066. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAGCTG CGGTGCTGAC CTTGGCCGTG CTCTTCCTGA CGGGGAGCCA GGCTCGGCAT 
TTCTGGCAGC AAGATGAACC CCCCCAGAGC CCCTGGGATC GAGTGAAGGA CCTGGCCACT
GTGTACGTGG ATGTGCTCAA AGACAGCGGC AGAGACTATG TGTCCCAGTT TGAAGGCTCC
GCCTTGGGAA AACAGCTAAA CCTAAAGCTC CTTGACAACT GGGACAGCGT GACCTCCACC
TTCAGCAAGC TGCGCGAACA GCTCGGCCCT GTGACCCAGG AGTTCTGGGA TAACCTGGAA
AAGGAGACAG AGGGCCTGAG GCAGGAGATG AGCAAGGATC TGGAGGAGGT GAAGGCCAAG
GTGCAGCCCT ACCTGGACGA CTTCCAGAAG AAGTGGCAGG AGGAGATGGA GCTCTACCGC
CAGAAGGTGG AGCCGCTGCG CGCAGAGCTC CAAGAGGGCG CGCGCCAGAA GCTGCACGAG
CTGCAAGAGA AGCTGAGCCC ACTGGGCGAG GAGATGCGCG ACCGCGCGCG CGCCCATGTG
GACGCGCTGC GCACGCATCT GGCCCCCTAC AGCGACGAGC TGCGCCAGCG CTTGGCCGCG
CGCCTTGAGG CTCTCAAGGA GAACGGCGGC GCCAGACTGG CCGAGTACCA CGCCAAGGCC
ACCGAGCATC TGAGCACGCT CAGCGAGAAG GCCAAGCCCG CGCTCGAGGA CCTCCGCCAA
GGCCTGCTGC CCGTGCTGGA GAGCTTCAAG GTCAGCTTCC TGAGCGCTCT CGAGGAGTAC
ACTAAGAAGC TCAACACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005271596.1
CDS110..913
Misc Feature(1)383..883(+)
Translation

Target ORF information:

RefSeq Version XM_005271539
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens apolipoprotein A-I (APOA1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005271539

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAGCTG CGGTGCTGAC CTTGGCCGTG CTCTTCCTGA CGGGGAGCCA GGCTCGGCAT 
TTCTGGCAGC AAGATGAACC CCCCCAGAGC CCCTGGGATC GAGTGAAGGA CCTGGCCACT
GTGTACGTGG ATGTGCTCAA AGACAGCGGC AGAGACTATG TGTCCCAGTT TGAAGGCTCC
GCCTTGGGAA AACAGCTAAA CCTAAAGCTC CTTGACAACT GGGACAGCGT GACCTCCACC
TTCAGCAAGC TGCGCGAACA GCTCGGCCCT GTGACCCAGG AGTTCTGGGA TAACCTGGAA
AAGGAGACAG AGGGCCTGAG GCAGGAGATG AGCAAGGATC TGGAGGAGGT GAAGGCCAAG
GTGCAGCCCT ACCTGGACGA CTTCCAGAAG AAGTGGCAGG AGGAGATGGA GCTCTACCGC
CAGAAGGTGG AGCCGCTGCG CGCAGAGCTC CAAGAGGGCG CGCGCCAGAA GCTGCACGAG
CTGCAAGAGA AGCTGAGCCC ACTGGGCGAG GAGATGCGCG ACCGCGCGCG CGCCCATGTG
GACGCGCTGC GCACGCATCT GGCCCCCTAC AGCGACGAGC TGCGCCAGCG CTTGGCCGCG
CGCCTTGAGG CTCTCAAGGA GAACGGCGGC GCCAGACTGG CCGAGTACCA CGCCAAGGCC
ACCGAGCATC TGAGCACGCT CAGCGAGAAG GCCAAGCCCG CGCTCGAGGA CCTCCGCCAA
GGCCTGCTGC CCGTGCTGGA GAGCTTCAAG GTCAGCTTCC TGAGCGCTCT CGAGGAGTAC
ACTAAGAAGC TCAACACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27099
Clone ID Related Accession (Same CDS sequence) NM_000039 , XM_005271539 , XM_005271540
Accession Version XM_005271540.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 804bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product apolipoprotein A-I isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_033899.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAGCTG CGGTGCTGAC CTTGGCCGTG CTCTTCCTGA CGGGGAGCCA GGCTCGGCAT 
TTCTGGCAGC AAGATGAACC CCCCCAGAGC CCCTGGGATC GAGTGAAGGA CCTGGCCACT
GTGTACGTGG ATGTGCTCAA AGACAGCGGC AGAGACTATG TGTCCCAGTT TGAAGGCTCC
GCCTTGGGAA AACAGCTAAA CCTAAAGCTC CTTGACAACT GGGACAGCGT GACCTCCACC
TTCAGCAAGC TGCGCGAACA GCTCGGCCCT GTGACCCAGG AGTTCTGGGA TAACCTGGAA
AAGGAGACAG AGGGCCTGAG GCAGGAGATG AGCAAGGATC TGGAGGAGGT GAAGGCCAAG
GTGCAGCCCT ACCTGGACGA CTTCCAGAAG AAGTGGCAGG AGGAGATGGA GCTCTACCGC
CAGAAGGTGG AGCCGCTGCG CGCAGAGCTC CAAGAGGGCG CGCGCCAGAA GCTGCACGAG
CTGCAAGAGA AGCTGAGCCC ACTGGGCGAG GAGATGCGCG ACCGCGCGCG CGCCCATGTG
GACGCGCTGC GCACGCATCT GGCCCCCTAC AGCGACGAGC TGCGCCAGCG CTTGGCCGCG
CGCCTTGAGG CTCTCAAGGA GAACGGCGGC GCCAGACTGG CCGAGTACCA CGCCAAGGCC
ACCGAGCATC TGAGCACGCT CAGCGAGAAG GCCAAGCCCG CGCTCGAGGA CCTCCGCCAA
GGCCTGCTGC CCGTGCTGGA GAGCTTCAAG GTCAGCTTCC TGAGCGCTCT CGAGGAGTAC
ACTAAGAAGC TCAACACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005271597.1
CDS75..878
Misc Feature(1)348..848(+)
Translation

Target ORF information:

RefSeq Version XM_005271540
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens apolipoprotein A-I (APOA1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005271540

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAGCTG CGGTGCTGAC CTTGGCCGTG CTCTTCCTGA CGGGGAGCCA GGCTCGGCAT 
TTCTGGCAGC AAGATGAACC CCCCCAGAGC CCCTGGGATC GAGTGAAGGA CCTGGCCACT
GTGTACGTGG ATGTGCTCAA AGACAGCGGC AGAGACTATG TGTCCCAGTT TGAAGGCTCC
GCCTTGGGAA AACAGCTAAA CCTAAAGCTC CTTGACAACT GGGACAGCGT GACCTCCACC
TTCAGCAAGC TGCGCGAACA GCTCGGCCCT GTGACCCAGG AGTTCTGGGA TAACCTGGAA
AAGGAGACAG AGGGCCTGAG GCAGGAGATG AGCAAGGATC TGGAGGAGGT GAAGGCCAAG
GTGCAGCCCT ACCTGGACGA CTTCCAGAAG AAGTGGCAGG AGGAGATGGA GCTCTACCGC
CAGAAGGTGG AGCCGCTGCG CGCAGAGCTC CAAGAGGGCG CGCGCCAGAA GCTGCACGAG
CTGCAAGAGA AGCTGAGCCC ACTGGGCGAG GAGATGCGCG ACCGCGCGCG CGCCCATGTG
GACGCGCTGC GCACGCATCT GGCCCCCTAC AGCGACGAGC TGCGCCAGCG CTTGGCCGCG
CGCCTTGAGG CTCTCAAGGA GAACGGCGGC GCCAGACTGG CCGAGTACCA CGCCAAGGCC
ACCGAGCATC TGAGCACGCT CAGCGAGAAG GCCAAGCCCG CGCTCGAGGA CCTCCGCCAA
GGCCTGCTGC CCGTGCTGGA GAGCTTCAAG GTCAGCTTCC TGAGCGCTCT CGAGGAGTAC
ACTAAGAAGC TCAACACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27099
Clone ID Related Accession (Same CDS sequence) NM_000039 , XM_005271539 , XM_005271540
Accession Version NM_000039.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 804bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product apolipoprotein A-I preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X02162.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X02162.1, BC110286.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144835 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAGCTG CGGTGCTGAC CTTGGCCGTG CTCTTCCTGA CGGGGAGCCA GGCTCGGCAT 
TTCTGGCAGC AAGATGAACC CCCCCAGAGC CCCTGGGATC GAGTGAAGGA CCTGGCCACT
GTGTACGTGG ATGTGCTCAA AGACAGCGGC AGAGACTATG TGTCCCAGTT TGAAGGCTCC
GCCTTGGGAA AACAGCTAAA CCTAAAGCTC CTTGACAACT GGGACAGCGT GACCTCCACC
TTCAGCAAGC TGCGCGAACA GCTCGGCCCT GTGACCCAGG AGTTCTGGGA TAACCTGGAA
AAGGAGACAG AGGGCCTGAG GCAGGAGATG AGCAAGGATC TGGAGGAGGT GAAGGCCAAG
GTGCAGCCCT ACCTGGACGA CTTCCAGAAG AAGTGGCAGG AGGAGATGGA GCTCTACCGC
CAGAAGGTGG AGCCGCTGCG CGCAGAGCTC CAAGAGGGCG CGCGCCAGAA GCTGCACGAG
CTGCAAGAGA AGCTGAGCCC ACTGGGCGAG GAGATGCGCG ACCGCGCGCG CGCCCATGTG
GACGCGCTGC GCACGCATCT GGCCCCCTAC AGCGACGAGC TGCGCCAGCG CTTGGCCGCG
CGCCTTGAGG CTCTCAAGGA GAACGGCGGC GCCAGACTGG CCGAGTACCA CGCCAAGGCC
ACCGAGCATC TGAGCACGCT CAGCGAGAAG GCCAAGCCCG CGCTCGAGGA CCTCCGCCAA
GGCCTGCTGC CCGTGCTGGA GAGCTTCAAG GTCAGCTTCC TGAGCGCTCT CGAGGAGTAC
ACTAAGAAGC TCAACACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000030.1
CDS39..842
Misc Feature(1)240..839(+)
Misc Feature(2)312..812(+)
Misc Feature(3)366..368(+)
Misc Feature(4)444..446(+)
Exon (1)1..18
Gene:APOA1
Gene Synonym:
Exon (2)19..81
Gene:APOA1
Gene Synonym:
Exon (3)82..238
Gene:APOA1
Gene Synonym:
Exon (4)239..897
Gene:APOA1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000039
Organism Homo sapiens (human)
Definition Homo sapiens apolipoprotein A-I (APOA1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000039

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGAAAGCTG CGGTGCTGAC CTTGGCCGTG CTCTTCCTGA CGGGGAGCCA GGCTCGGCAT 
TTCTGGCAGC AAGATGAACC CCCCCAGAGC CCCTGGGATC GAGTGAAGGA CCTGGCCACT
GTGTACGTGG ATGTGCTCAA AGACAGCGGC AGAGACTATG TGTCCCAGTT TGAAGGCTCC
GCCTTGGGAA AACAGCTAAA CCTAAAGCTC CTTGACAACT GGGACAGCGT GACCTCCACC
TTCAGCAAGC TGCGCGAACA GCTCGGCCCT GTGACCCAGG AGTTCTGGGA TAACCTGGAA
AAGGAGACAG AGGGCCTGAG GCAGGAGATG AGCAAGGATC TGGAGGAGGT GAAGGCCAAG
GTGCAGCCCT ACCTGGACGA CTTCCAGAAG AAGTGGCAGG AGGAGATGGA GCTCTACCGC
CAGAAGGTGG AGCCGCTGCG CGCAGAGCTC CAAGAGGGCG CGCGCCAGAA GCTGCACGAG
CTGCAAGAGA AGCTGAGCCC ACTGGGCGAG GAGATGCGCG ACCGCGCGCG CGCCCATGTG
GACGCGCTGC GCACGCATCT GGCCCCCTAC AGCGACGAGC TGCGCCAGCG CTTGGCCGCG
CGCCTTGAGG CTCTCAAGGA GAACGGCGGC GCCAGACTGG CCGAGTACCA CGCCAAGGCC
ACCGAGCATC TGAGCACGCT CAGCGAGAAG GCCAAGCCCG CGCTCGAGGA CCTCCGCCAA
GGCCTGCTGC CCGTGCTGGA GAGCTTCAAG GTCAGCTTCC TGAGCGCTCT CGAGGAGTAC
ACTAAGAAGC TCAACACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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