KRTAP10-5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTAP10-5
Entrez Gene ID	386680
Full Name	keratin associated protein 10-5
Synonyms	KAP10.5,KAP18-5,KAP18.5,KRTAP10.5,KRTAP18-5,KRTAP18.1,KRTAP18.5
General protein information	Preferred Names keratin associated protein 10-5 Names keratin-associated protein 10-5 high sulfur keratin-associated protein 10.5 keratin-associated protein 18.5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q22.3
Summary	This is an intronless gene located in a cluster of related genes on the q arm of chromosome 21. The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins, thereby contributing to the structure and stability of hair fibers. [provided by RefSeq, Apr 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_198694.3	NP_941967.3	keratin-associated protein 10-5

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KRTAP10-5	XP_001152687.1
Homo sapiens (human)	KRTAP10-5	NP_941967.2
	KRTAP10-3	XP_002803153.1
	LOC711745	XP_001102966.1

Gene Ontology
Bibliography

Related articles in PubMed

A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.
Shibuya K, Obayashi I, Asakawa S, Minoshima S, Kudoh J, Shimizu N
Genomics83(4)679-93(2004 Apr)

Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.
Rogers MA, Langbein L, Winter H, Beckmann I, Praetzel S, Schweizer J
The Journal of investigative dermatology122(1)147-58(2004 Jan)

Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.
Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Schweizer J
The Journal of biological chemistry277(50)48993-9002(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRTAP10-5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP10-5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu16132	NM_198694.3 Latest version!	Homo sapiens keratin associated protein 10-5 (KRTAP10-5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTAP10-5 ( NM_198694.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_941967.3 Homo sapiens keratin associated protein 10-5 (KRTAP10-5), mRNA.

Price & Availability↑

CloneID	OHu16132
Clone ID Related Accession (Same CDS sequence)	NM_198694.3
Accession Version	NM_198694.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	keratin-associated protein 10-5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AP001067.1. On Apr 18, 2014 this sequence version replaced NM_198694.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000400372.1/ ENSP00000383223.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCGT GCACCATGTC CGTCTGCTCC AGCGCTTGCT CTGACTCCTG GCGAGTGGAC 
GACTGCCCAG AGAGCTGCTG TGAGCCCCCC TGCGGCACCG CCCCCTGCCT GACCCTGGTC 
TGCACCCCAG TGAGCTGTGT GTCCAGCCCC TGCTGCCAGG CGGCCTGTGA GCCCAGCCCC 
TGCCAATCAG GCTGCACCAG CTCCTGCACG CCCTCGTGCT GCCAGCCGGC TTGCTGCGCC 
TCCTCCCCCT GCCAGCAGGC CTGCTGCGTG CCCGTCTGCT GCAAGCCTGT GTGCTGCCTG 
CCCACCTGCT CTAAGGATTC CTCTTCATGC TGCCAGCAGT CTAGCTGCCA GCCAACTTGC 
TGTGCCTCTT CCTCCTGCCA GCAGTCCTGC TGTGTGCCTG TCTGCTGCAA GCCCGTGTGC 
TGTGTGCCCA CCTGTTCTGA GGATTCCTCT TCATGCTGCC AGCATTCTAG CTGCCAGCCG 
ACTTGCTGCA CCTCCTCCCC CTGCCAGCAG TCCTGCTACG TGCCTGTCTG TTGCAAGCCT 
GTCTGCTGCA AACCCATCTG CTGTGTGCCC GTCTGCTCTG GGGCTTCCAC TTCATGCTGC 
CAGCAGTCTA GCTGTCAGCC GGCTTGCTGC ACCACCTCCT GCTGCAGACC CTCCTCCTCC 
GTGTCCCTCC TCTGCCGCCC CATATGCAGG CCCGCCTGCT GCCTGCCCAT CTCCTCCTGC 
TGTGCCCCTG CCTCCTCCTA CCAGGCCAGC TGCTGCCGCC CGGCCTCCTG CGTGTCCCTC 
CTCTGCCGCC CCGCGTGCTC CCCCCTGGCC TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_941967.3
CDS	27..842
Translation	MAACTMSVCSSACSDSWRVDDCPESCCEPPCGTAPCLTLVCTPVSCVSSPCCQAACEPSPCQSGCTSSCTPSCCQPACCASSPCQQACCVPVCCKPVCCLPTCSKDSSSCCQQSSCQPTCCASSSCQQSCCVPVCCKPVCCVPTCSEDSSSCCQHSSCQPTCCTSSPCQQSCYVPVCCKPVCCKPICCVPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPICRPACCLPISSCCAPASSYQASCCRPASCVSLLCRPACSPLAC

Target ORF information:

RefSeq Version	NM_198694.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 10-5 (KRTAP10-5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198694.3

ORF Insert Sequence:

ATGGCCGCGT GCACCATGTC CGTCTGCTCC AGCGCTTGCT CTGACTCCTG GCGAGTGGAC 
GACTGCCCAG AGAGCTGCTG TGAGCCCCCC TGCGGCACCG CCCCCTGCCT GACCCTGGTC 
TGCACCCCAG TGAGCTGTGT GTCCAGCCCC TGCTGCCAGG CGGCCTGTGA GCCCAGCCCC 
TGCCAATCAG GCTGCACCAG CTCCTGCACG CCCTCGTGCT GCCAGCCGGC TTGCTGCGCC 
TCCTCCCCCT GCCAGCAGGC CTGCTGCGTG CCCGTCTGCT GCAAGCCTGT GTGCTGCCTG 
CCCACCTGCT CTAAGGATTC CTCTTCATGC TGCCAGCAGT CTAGCTGCCA GCCAACTTGC 
TGTGCCTCTT CCTCCTGCCA GCAGTCCTGC TGTGTGCCTG TCTGCTGCAA GCCCGTGTGC 
TGTGTGCCCA CCTGTTCTGA GGATTCCTCT TCATGCTGCC AGCATTCTAG CTGCCAGCCG 
ACTTGCTGCA CCTCCTCCCC CTGCCAGCAG TCCTGCTACG TGCCTGTCTG TTGCAAGCCT 
GTCTGCTGCA AACCCATCTG CTGTGTGCCC GTCTGCTCTG GGGCTTCCAC TTCATGCTGC 
CAGCAGTCTA GCTGTCAGCC GGCTTGCTGC ACCACCTCCT GCTGCAGACC CTCCTCCTCC 
GTGTCCCTCC TCTGCCGCCC CATATGCAGG CCCGCCTGCT GCCTGCCCAT CTCCTCCTGC 
TGTGCCCCTG CCTCCTCCTA CCAGGCCAGC TGCTGCCGCC CGGCCTCCTG CGTGTCCCTC 
CTCTGCCGCC CCGCGTGCTC CCCCCTGGCC TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.
Genomics83(4)679-93(2004 Apr)
Shibuya K,Obayashi I,Asakawa S,Minoshima S,Kudoh J,Shimizu N

Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.
The Journal of investigative dermatology122(1)147-58(2004 Jan)
Rogers MA,Langbein L,Winter H,Beckmann I,Praetzel S,Schweizer J

Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.
The Journal of biological chemistry277(50)48993-9002(2002 Dec)
Rogers MA,Langbein L,Winter H,Ehmann C,Praetzel S,Schweizer J