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GBP7 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GBP7
Entrez Gene ID 388646
Full Name guanylate binding protein 7
Synonyms GBP4L
General protein information
Preferred Names
guanylate-binding protein 7
Names
guanylate-binding protein 7
GBP-7
GTP-binding protein 7
guanine nucleotide-binding protein 7
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p22.2

Summary Guanylate-binding proteins, such as GBP7, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008]. lac of sum
Disorder MIM:

612468


mRNA and Protein(s)

mRNA Protein Name
NM_207398 NP_997281 guanylate-binding protein 7



Homo sapiens (human) GBP7 NP_997281.2
Pan troglodytes (chimpanzee) GBP7 XP_003949504.1
Mus musculus (house mouse) Gbp7 NP_663520.2
Rattus norvegicus (Norway rat) LOC685067 XP_003749457.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GBP7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GBP7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu03138 NM_207398 Homo sapiens guanylate binding protein 7 (GBP7), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu03138
Clone ID Related Accession (Same CDS sequence) NM_207398
Accession Version NM_207398.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1917bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product guanylate-binding protein 7
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK096141.1 and AC104459.2. On May 23, 2007 this sequence version replaced gi:46409419. Sequence Note: This sequence has been modified as follows: removed 36 bp suspected to be vector contamination from the 3' end. ##Evidence-Data-START## Transcript exon combination :: AK096141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGGCATCAG AGATCCACAT GCCAGGCCCA GTGTGCCTCA CTGAGAACAC TAAAGGGCAT 
CTGGTGGTGA ATTCAGAAGC TCTGGAAATC CTGTCTGCCA TTACACAGCC TGTAGTAGTG
GTGGCAATTG TGGGCCTCTA CCGCACAGGC AAATCCTACC TAATGAACAA GCTGGCTGGG
AAGAACAAAG GCTTCCCTCT GGGCTGCACA GTGAAGTCTG AAACCAAAGG CATCTGGATG
TGGTGTGTGC CCCACCCCTC CAAGCCAAAC CACACCCTGA TCCTTCTGGA CACGGAGGGC
CTGGGTGATA TGGAAAAGAG TGACCCTAAG AGTGACTCGT GGATCTTTGC CCTGGCTGTG
CTTCTAAGCA GCAGCTTTGT CTACAACAGC ATGGGCACCA TCAACCACCA GGCCCTGGAG
CAGCTGCACT ACGTGACTGA GCTAACAGAG CTAATCAGGG CAAAATCGTG CCCCAGACCT
GATGAAGTTG AGGACTCCAG CGAGTTTGTG AGTTTCTTTC CAGACTTTAT TTGGACTGTT
CGAGATTTTA CCCTGGAGCT GAAGTTAGAT GGACACCCCA TCACAGAAGA TGAGTACCTG
GAGAATGCCT TGAAGCTGAT TTCAGGCAAG AATCCCCAAA TCCAAAATTC TAACAAGCCC
AGGGAGTGGA TCAGGCATTT CTTTCCAAAA CAGAAGTGCT TTGTCTTTGA CCGGCCAATA
AATGACAAAA AACTCTTACT CCATGTTGAA GAAGTACGAG AAGACCAACT GGATAGTAAT
TTCCAGATGC AATCAGAAAA TTTCTGTTCT TATATCTTCA CCCATGCAAA GACCAAGACC
CTGAGAGAGG GAATCCTTGT CACTGGAAAC CGGCTGGGGA TGCTGGTGGA GACCTACCTG
GATGCCATCA ACAGTGGAGC GACTCCTTGT CTGGAGAATG CAATGGCAGT TCTGGCCCAG
TGTGAGAACT CAGCAGCCGT GCAGAGGGCA GCCAACCACT ACAGCCAGCA GATGGCCCAG
CAAGTGAGAT TCCCCACAGA CACACTCCAG GAGCTGCTGG ACGTGCATGC AGTTTGTGAG
AGGGAAGCCA TTGCAGTCTT CATGGAGTAC TCCTTCAAAG ATAAAAGCCA GGAATTTCAG
AAGAAGCTTG TGGACACCAT GGAGAAAAAG AAGGAAGACT TTGTGCTGCA GAATGAAGAG
GCATCTGCCA AATATTGTCA GGCTGAGCTT AAGCGGCTTT CAGAGCTCTT GACAGAAAGT
ATTTCAAGAG GAACTTTCTT TGTTCCGGGG GGGCACAATA TCTACTTAGA AGCAAAAAAG
AAGATTGAAC AGGACTATAC ACTAGTGCCC AGAAAAGGAG TTAAGGCAGA CGAGGTCCTC
CAGAGCTTCC TGCAGTCACA GGTGGTTATA GAGGAATCCA TCCTGCAGTC AGACAAAGCC
CTCACTGCTG GAGAGAAGGC CATAGCAGCT AAGCAGGCTA AGAAGGAGGC AGCTGAAAAG
GAACAGGAGC TGCTAAGACA AAAACAGAAG GAACAGCAGC AAATGATGGA GGCTCAAGAG
AGAAGTTTCC AGGAAAACAT AGCTCAACTC AAGAAGAAGA TGGAGAGGGA AAGGGAAAAC
TATATGAGAG AACTGAGAAA GATGTTGAGT CACAAGATGA AGGTCCTAGA AGAACTGCTT
ACTGAAGGAT TTAAAGAGAT ATTTGAGTCG TTAAATGAAG AGATTAATCG ACTGAAAGAA
CAAATTGAAG CAGCTGAAAA TGAAGAGCCC TCAGTGTTTT CACAGATTCT TGATGTGGCT
GGCAGTATAT TTATTGCAGC ACTACCTGGG GCTGCTAAGC TAGTTGATTT AGGAATGAAA
ATTCTTAGCT CATTATGTAA TAGGCTGAGA AATCCTGGTA AGAAAATTAT AAGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_997281.2
CDS140..2056
Misc Feature(1)140..1069(+)
Misc Feature(2)233..961(+)
Misc Feature(3)272..295(+)
Misc Feature(4)278..856(+)
Misc Feature(5)329..382(+)
Misc Feature(6)362..364(+)
Misc Feature(7)428..439(+)
Misc Feature(8)434..514(+)
Misc Feature(9)680..691(+)
Misc Feature(10)848..856(+)
Misc Feature(11)986..1876(+)
Misc Feature(12)1703..1963(+)
Exon (1)1..120
Gene:GBP7
Gene Synonym:
Exon (2)121..329
Gene:GBP7
Gene Synonym:
Exon (3)330..457
Gene:GBP7
Gene Synonym:
Exon (4)458..567
Gene:GBP7
Gene Synonym:
Exon (5)568..764
Gene:GBP7
Gene Synonym:
Exon (6)765..1010
Gene:GBP7
Gene Synonym:
Exon (7)1011..1291
Gene:GBP7
Gene Synonym:
Exon (8)1292..1504
Gene:GBP7
Gene Synonym:
Exon (9)1505..1607
Gene:GBP7
Gene Synonym:
Exon (10)1608..1801
Gene:GBP7
Gene Synonym:
Exon (11)1802..2454
Gene:GBP7
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_207398
Organism Homo sapiens (human)
Definition Homo sapiens guanylate binding protein 7 (GBP7), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_207398

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGGCATCAG AGATCCACAT GCCAGGCCCA GTGTGCCTCA CTGAGAACAC TAAAGGGCAT 
CTGGTGGTGA ATTCAGAAGC TCTGGAAATC CTGTCTGCCA TTACACAGCC TGTAGTAGTG
GTGGCAATTG TGGGCCTCTA CCGCACAGGC AAATCCTACC TAATGAACAA GCTGGCTGGG
AAGAACAAAG GCTTCCCTCT GGGCTGCACA GTGAAGTCTG AAACCAAAGG CATCTGGATG
TGGTGTGTGC CCCACCCCTC CAAGCCAAAC CACACCCTGA TCCTTCTGGA CACGGAGGGC
CTGGGTGATA TGGAAAAGAG TGACCCTAAG AGTGACTCGT GGATCTTTGC CCTGGCTGTG
CTTCTAAGCA GCAGCTTTGT CTACAACAGC ATGGGCACCA TCAACCACCA GGCCCTGGAG
CAGCTGCACT ACGTGACTGA GCTAACAGAG CTAATCAGGG CAAAATCGTG CCCCAGACCT
GATGAAGTTG AGGACTCCAG CGAGTTTGTG AGTTTCTTTC CAGACTTTAT TTGGACTGTT
CGAGATTTTA CCCTGGAGCT GAAGTTAGAT GGACACCCCA TCACAGAAGA TGAGTACCTG
GAGAATGCCT TGAAGCTGAT TTCAGGCAAG AATCCCCAAA TCCAAAATTC TAACAAGCCC
AGGGAGTGGA TCAGGCATTT CTTTCCAAAA CAGAAGTGCT TTGTCTTTGA CCGGCCAATA
AATGACAAAA AACTCTTACT CCATGTTGAA GAAGTACGAG AAGACCAACT GGATAGTAAT
TTCCAGATGC AATCAGAAAA TTTCTGTTCT TATATCTTCA CCCATGCAAA GACCAAGACC
CTGAGAGAGG GAATCCTTGT CACTGGAAAC CGGCTGGGGA TGCTGGTGGA GACCTACCTG
GATGCCATCA ACAGTGGAGC GACTCCTTGT CTGGAGAATG CAATGGCAGT TCTGGCCCAG
TGTGAGAACT CAGCAGCCGT GCAGAGGGCA GCCAACCACT ACAGCCAGCA GATGGCCCAG
CAAGTGAGAT TCCCCACAGA CACACTCCAG GAGCTGCTGG ACGTGCATGC AGTTTGTGAG
AGGGAAGCCA TTGCAGTCTT CATGGAGTAC TCCTTCAAAG ATAAAAGCCA GGAATTTCAG
AAGAAGCTTG TGGACACCAT GGAGAAAAAG AAGGAAGACT TTGTGCTGCA GAATGAAGAG
GCATCTGCCA AATATTGTCA GGCTGAGCTT AAGCGGCTTT CAGAGCTCTT GACAGAAAGT
ATTTCAAGAG GAACTTTCTT TGTTCCGGGG GGGCACAATA TCTACTTAGA AGCAAAAAAG
AAGATTGAAC AGGACTATAC ACTAGTGCCC AGAAAAGGAG TTAAGGCAGA CGAGGTCCTC
CAGAGCTTCC TGCAGTCACA GGTGGTTATA GAGGAATCCA TCCTGCAGTC AGACAAAGCC
CTCACTGCTG GAGAGAAGGC CATAGCAGCT AAGCAGGCTA AGAAGGAGGC AGCTGAAAAG
GAACAGGAGC TGCTAAGACA AAAACAGAAG GAACAGCAGC AAATGATGGA GGCTCAAGAG
AGAAGTTTCC AGGAAAACAT AGCTCAACTC AAGAAGAAGA TGGAGAGGGA AAGGGAAAAC
TATATGAGAG AACTGAGAAA GATGTTGAGT CACAAGATGA AGGTCCTAGA AGAACTGCTT
ACTGAAGGAT TTAAAGAGAT ATTTGAGTCG TTAAATGAAG AGATTAATCG ACTGAAAGAA
CAAATTGAAG CAGCTGAAAA TGAAGAGCCC TCAGTGTTTT CACAGATTCT TGATGTGGCT
GGCAGTATAT TTATTGCAGC ACTACCTGGG GCTGCTAAGC TAGTTGATTT AGGAATGAAA
ATTCTTAGCT CATTATGTAA TAGGCTGAGA AATCCTGGTA AGAAAATTAT AAGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring
Malar. J. 9, 119 (2010)
Eid NA, Hussein AA, Elzein AM, Mohamed HS, Rockett KA, Kwiatkowski DP and Ibrahim ME.


book

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters
J. Interferon Cytokine Res. 26 (5), 328-352 (2006)
Olszewski MA, Gray J and Vestal DJ.


 
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