×

GDF6 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol GDF6
Entrez Gene ID 392255
Full Name growth differentiation factor 6
Synonyms BMP-13,BMP13,CDMP2,KFM,KFS,KFS1,KFSL,SGM1
General protein information
Preferred Names

growth differentiation factor 6

Names

growth/differentiation factor 6
bone morphogenetic protein 13
growth/differentiation factor 16

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

8

8q22.1

Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016].
Disorder MIM:

601147

Disorder Html: Klippel-Feil syndrome 1, autosomal dominant, 118100 (3);

mRNA and Protein(s)

mRNA Protein Name
NM_001001557.2 NP_001001557.1 growth/differentiation factor 6 precursor
NM_001001557.3 NP_001001557.1 growth/differentiation factor 6 preproprotein



Homo sapiens (human) GDF6 NP_001001557.1
Mus musculus (house mouse) Gdf6 NP_038554.1
Danio rerio (zebrafish) gdf6a NP_001153466.1
Xenopus tropicalis (tropical clawed frog) gdf6 NP_001016077.1
Bos taurus (cattle) GDF6 NP_001001140.1
Macaca mulatta (rhesus monkey) GDF6 XP_001090825.1
Pan troglodytes (chimpanzee) GDF6 XP_003311926.1
Rattus norvegicus (Norway rat) Gdf6 NP_001013056.1


Related articles in PubMed

A New Subtype of Multiple Synostoses Syndrome Is Caused by a Mutation in GDF6 That Decreases Its Sensitivity to Noggin and Enhances Its Potency as a BMP Signal.
Wang J, Yu T, Wang Z, Ohte S, Yao RE, Zheng Z, Geng J, Cai H, Ge Y, Li Y, Xu Y, Zhang Q, Gusella JF, Fu Q, Pregizer S, Rosen V, Shen Y
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research31(4)882-9(2016 Apr)

Expression of growth differentiation factor 6 in the human developing fetal spine retreats from vertebral ossifying regions and is restricted to cartilaginous tissues.
Wei A, Shen B, Williams LA, Bhargav D, Gulati T, Fang Z, Pathmanandavel S, Diwan AD
Journal of orthopaedic research : official publication of the Orthopaedic Research Society34(2)279-89(2016 Feb)

Localization of bone morphogenetic protein 13 in human intervertebral disc and its molecular and functional effects in vitro in 3D culture.
Gulati T, Chung SA, Wei AQ, Diwan AD
Journal of orthopaedic research : official publication of the Orthopaedic Research Society33(12)1769-75(2015 Dec)

Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis.
Banka S, Cain SA, Carim S, Daly SB, Urquhart JE, Erdem G, Harris J, Bottomley M, Donnai D, Kerr B, Kingston H, Superti-Furga A, Unger S, Ennis H, Worthington J, Herrick AL, Merry CL, Yue WW, Kielty CM, Newman WG
Annals of the rheumatic diseases74(6)1249-56(2015 Jun)

Association of rs6982567 near GDF6 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Han Chinese cohort.
Ji Y, Zhang X, Wu K, Su Y, Li M, Zuo C, Wen F
BMC ophthalmology14140(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings indicate that increased BMP signaling owing to a GDF6 gain-of-function mutation is responsible for loss of joint formation and profound functional impairment in patients with Multiple Synostoses Syndrome 4.
Title: A New Subtype of Multiple Synostoses Syndrome Is Caused by a Mutation in GDF6 That Decreases Its Sensitivity to Noggin and Enhances Its Potency as a BMP Signal.

As fetal age increased, the expression of growth differentiation factor 6 was decreased correspondingly with the progress of ossification in vertebral bodies and restricted to cartilaginous regions.
Title: Expression of growth differentiation factor 6 in the human developing fetal spine retreats from vertebral ossifying regions and is restricted to cartilaginous tissues.

BMP13 has a role in enhancing extracellular matrix accumulation and inducing cell migration in certain intervertebral disc cells
Title: Localization of bone morphogenetic protein 13 in human intervertebral disc and its molecular and functional effects in vitro in 3D culture.

GDF6 is overexpressed in Leri's pleonosteosis.
Title: Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis.

There was a possible weak association between the rs6982567 near GDF6 and polypoidal choroidal vasculopathy in this replication study with an independent Han Chinese cohort.
Title: Association of rs6982567 near GDF6 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Han Chinese cohort.

The following GDF6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GDF6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

Free DYK Tag Antibody

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu18538 NM_001001557.3
Latest version!
Homo sapiens growth differentiation factor 6 (GDF6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
View Old Accession Versions >>
OHu18538 NM_001001557.2 Homo sapiens growth differentiation factor 6 (GDF6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu18538
Clone ID Related Accession (Same CDS sequence) NM_001001557.2 , NM_001001557.3
Accession Version NM_001001557.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1368bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-15
Organism Homo sapiens(Human)
Product growth/differentiation factor 6 precursor
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGATACTC CCAGGGTCCT GCTCTCGGCC GTCTTCCTCA TCAGTTTTCT GTGGGATTTG 
CCCGGTTTCC AGCAGGCTTC CATCTCATCC TCCTCGTCGT CCGCCGAGCT GGGTTCCACC
AAGGGCATGC GAAGCCGCAA GGAAGGCAAG ATGCAGCGGG CGCCGCGCGA CAGTGACGCG
GGCCGGGAGG GCCAGGAACC ACAGCCGCGG CCTCAGGACG AACCCCGGGC TCAGCAGCCC
CGGGCGCAGG AGCCGCCAGG CAGGGGTCCG CGCGTGGTGC CCCACGAGTA CATGCTGTCA
ATCTACAGGA CTTACTCCAT CGCTGAGAAG CTGGGCATCA ATGCCAGCTT TTTCCAGTCT
TCCAAGTCGG CTAATACGAT CACCAGCTTT GTAGACAGGG GACTAGACGA TCTCTCGCAC
ACTCCTCTCC GGAGACAGAA GTATTTGTTT GATGTGTCCA TGCTCTCAGA CAAAGAAGAG
CTGGTGGGCG CGGAGCTGCG GCTCTTTCGC CAGGCGCCCT CAGCGCCCTG GGGGCCACCA
GCCGGGCCGC TCCACGTGCA GCTCTTCCCT TGCCTTTCGC CCCTACTGCT GGACGCGCGG
ACCCTGGACC CGCAGGGGGC GCCGCCGGCC GGCTGGGAAG TCTTCGACGT GTGGCAGGGC
CTGCGCCACC AGCCCTGGAA GCAGCTGTGC TTGGAGCTGC GGGCCGCATG GGGCGAGCTG
GACGCCGGGG AGGCCGAGGC GCGCGCGCGG GGACCCCAGC AACCGCCGCC CCCGGACCTG
CGGAGTCTGG GCTTCGGCCG GAGGGTGCGG CCTCCCCAGG AGCGGGCCCT GCTGGTGGTA
TTCACCAGAT CCCAGCGCAA GAACCTGTTC GCAGAGATGC GCGAGCAGCT GGGCTCGGCC
GAGGCTGCGG GCCCGGGCGC GGGCGCCGAG GGGTCGTGGC CGCCGCCGTC GGGCGCCCCG
GATGCCAGGC CTTGGCTGCC CTCGCCCGGC CGCCGGCGGC GGCGCACGGC CTTCGCCAGT
CGCCATGGCA AGCGGCACGG CAAGAAGTCC AGGCTACGCT GCAGCAAGAA GCCCCTGCAC
GTGAACTTCA AGGAGCTGGG CTGGGACGAC TGGATTATCG CGCCCCTGGA GTACGAGGCC
TATCACTGCG AGGGTGTATG CGACTTCCCG CTGCGCTCGC ACCTGGAGCC CACCAACCAC
GCCATCATCC AGACGCTGAT GAACTCCATG GACCCCGGCT CCACCCCGCC CAGCTGCTGC
GTGCCCACCA AATTGACTCC CATCAGCATT CTATACATCG ACGCGGGCAA TAATGTGGTC
TACAAGCAGT ACGAGGACAT GGTGGTGGAG TCGTGCGGCT GCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001001557.1
Translation

Target ORF information:

RefSeq Version NM_001001557.2
Organism Homo sapiens(Human)
Definition Homo sapiens growth differentiation factor 6 (GDF6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001001557.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGATACTC CCAGGGTCCT GCTCTCGGCC GTCTTCCTCA TCAGTTTTCT GTGGGATTTG 
CCCGGTTTCC AGCAGGCTTC CATCTCATCC TCCTCGTCGT CCGCCGAGCT GGGTTCCACC
AAGGGCATGC GAAGCCGCAA GGAAGGCAAG ATGCAGCGGG CGCCGCGCGA CAGTGACGCG
GGCCGGGAGG GCCAGGAACC ACAGCCGCGG CCTCAGGACG AACCCCGGGC TCAGCAGCCC
CGGGCGCAGG AGCCGCCAGG CAGGGGTCCG CGCGTGGTGC CCCACGAGTA CATGCTGTCA
ATCTACAGGA CTTACTCCAT CGCTGAGAAG CTGGGCATCA ATGCCAGCTT TTTCCAGTCT
TCCAAGTCGG CTAATACGAT CACCAGCTTT GTAGACAGGG GACTAGACGA TCTCTCGCAC
ACTCCTCTCC GGAGACAGAA GTATTTGTTT GATGTGTCCA TGCTCTCAGA CAAAGAAGAG
CTGGTGGGCG CGGAGCTGCG GCTCTTTCGC CAGGCGCCCT CAGCGCCCTG GGGGCCACCA
GCCGGGCCGC TCCACGTGCA GCTCTTCCCT TGCCTTTCGC CCCTACTGCT GGACGCGCGG
ACCCTGGACC CGCAGGGGGC GCCGCCGGCC GGCTGGGAAG TCTTCGACGT GTGGCAGGGC
CTGCGCCACC AGCCCTGGAA GCAGCTGTGC TTGGAGCTGC GGGCCGCATG GGGCGAGCTG
GACGCCGGGG AGGCCGAGGC GCGCGCGCGG GGACCCCAGC AACCGCCGCC CCCGGACCTG
CGGAGTCTGG GCTTCGGCCG GAGGGTGCGG CCTCCCCAGG AGCGGGCCCT GCTGGTGGTA
TTCACCAGAT CCCAGCGCAA GAACCTGTTC GCAGAGATGC GCGAGCAGCT GGGCTCGGCC
GAGGCTGCGG GCCCGGGCGC GGGCGCCGAG GGGTCGTGGC CGCCGCCGTC GGGCGCCCCG
GATGCCAGGC CTTGGCTGCC CTCGCCCGGC CGCCGGCGGC GGCGCACGGC CTTCGCCAGT
CGCCATGGCA AGCGGCACGG CAAGAAGTCC AGGCTACGCT GCAGCAAGAA GCCCCTGCAC
GTGAACTTCA AGGAGCTGGG CTGGGACGAC TGGATTATCG CGCCCCTGGA GTACGAGGCC
TATCACTGCG AGGGTGTATG CGACTTCCCG CTGCGCTCGC ACCTGGAGCC CACCAACCAC
GCCATCATCC AGACGCTGAT GAACTCCATG GACCCCGGCT CCACCCCGCC CAGCTGCTGC
GTGCCCACCA AATTGACTCC CATCAGCATT CTATACATCG ACGCGGGCAA TAATGTGGTC
TACAAGCAGT ACGAGGACAT GGTGGTGGAG TCGTGCGGCT GCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18538
Clone ID Related Accession (Same CDS sequence) NM_001001557.2 , NM_001001557.3
Accession Version NM_001001557.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1368bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-09-08
Organism Homo sapiens(Human)
Product growth/differentiation factor 6 preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ537424.1 and CA423567.1. This sequence is a reference standard in the RefSeqGene project. On Sep 3, 2016 this sequence version replaced NM_001001557.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ537424.1, CN282698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGATACTC CCAGGGTCCT GCTCTCGGCC GTCTTCCTCA TCAGTTTTCT GTGGGATTTG 
CCCGGTTTCC AGCAGGCTTC CATCTCATCC TCCTCGTCGT CCGCCGAGCT GGGTTCCACC
AAGGGCATGC GAAGCCGCAA GGAAGGCAAG ATGCAGCGGG CGCCGCGCGA CAGTGACGCG
GGCCGGGAGG GCCAGGAACC ACAGCCGCGG CCTCAGGACG AACCCCGGGC TCAGCAGCCC
CGGGCGCAGG AGCCGCCAGG CAGGGGTCCG CGCGTGGTGC CCCACGAGTA CATGCTGTCA
ATCTACAGGA CTTACTCCAT CGCTGAGAAG CTGGGCATCA ATGCCAGCTT TTTCCAGTCT
TCCAAGTCGG CTAATACGAT CACCAGCTTT GTAGACAGGG GACTAGACGA TCTCTCGCAC
ACTCCTCTCC GGAGACAGAA GTATTTGTTT GATGTGTCCA TGCTCTCAGA CAAAGAAGAG
CTGGTGGGCG CGGAGCTGCG GCTCTTTCGC CAGGCGCCCT CAGCGCCCTG GGGGCCACCA
GCCGGGCCGC TCCACGTGCA GCTCTTCCCT TGCCTTTCGC CCCTACTGCT GGACGCGCGG
ACCCTGGACC CGCAGGGGGC GCCGCCGGCC GGCTGGGAAG TCTTCGACGT GTGGCAGGGC
CTGCGCCACC AGCCCTGGAA GCAGCTGTGC TTGGAGCTGC GGGCCGCATG GGGCGAGCTG
GACGCCGGGG AGGCCGAGGC GCGCGCGCGG GGACCCCAGC AACCGCCGCC CCCGGACCTG
CGGAGTCTGG GCTTCGGCCG GAGGGTGCGG CCTCCCCAGG AGCGGGCCCT GCTGGTGGTA
TTCACCAGAT CCCAGCGCAA GAACCTGTTC GCAGAGATGC GCGAGCAGCT GGGCTCGGCC
GAGGCTGCGG GCCCGGGCGC GGGCGCCGAG GGGTCGTGGC CGCCGCCGTC GGGCGCCCCG
GATGCCAGGC CTTGGCTGCC CTCGCCCGGC CGCCGGCGGC GGCGCACGGC CTTCGCCAGT
CGCCATGGCA AGCGGCACGG CAAGAAGTCC AGGCTACGCT GCAGCAAGAA GCCCCTGCAC
GTGAACTTCA AGGAGCTGGG CTGGGACGAC TGGATTATCG CGCCCCTGGA GTACGAGGCC
TATCACTGCG AGGGTGTATG CGACTTCCCG CTGCGCTCGC ACCTGGAGCC CACCAACCAC
GCCATCATCC AGACGCTGAT GAACTCCATG GACCCCGGCT CCACCCCGCC CAGCTGCTGC
GTGCCCACCA AATTGACTCC CATCAGCATT CTATACATCG ACGCGGGCAA TAATGTGGTC
TACAAGCAGT ACGAGGACAT GGTGGTGGAG TCGTGCGGCT GCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001001557.1
CDS101..1468
Misc Feature(1)308..943
Misc Feature(2)1157..1462
Exon (1)1..506
Exon (2)507..3698
Translation

Target ORF information:

RefSeq Version NM_001001557.3
Organism Homo sapiens(Human)
Definition Homo sapiens growth differentiation factor 6 (GDF6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001001557.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGATACTC CCAGGGTCCT GCTCTCGGCC GTCTTCCTCA TCAGTTTTCT GTGGGATTTG 
CCCGGTTTCC AGCAGGCTTC CATCTCATCC TCCTCGTCGT CCGCCGAGCT GGGTTCCACC
AAGGGCATGC GAAGCCGCAA GGAAGGCAAG ATGCAGCGGG CGCCGCGCGA CAGTGACGCG
GGCCGGGAGG GCCAGGAACC ACAGCCGCGG CCTCAGGACG AACCCCGGGC TCAGCAGCCC
CGGGCGCAGG AGCCGCCAGG CAGGGGTCCG CGCGTGGTGC CCCACGAGTA CATGCTGTCA
ATCTACAGGA CTTACTCCAT CGCTGAGAAG CTGGGCATCA ATGCCAGCTT TTTCCAGTCT
TCCAAGTCGG CTAATACGAT CACCAGCTTT GTAGACAGGG GACTAGACGA TCTCTCGCAC
ACTCCTCTCC GGAGACAGAA GTATTTGTTT GATGTGTCCA TGCTCTCAGA CAAAGAAGAG
CTGGTGGGCG CGGAGCTGCG GCTCTTTCGC CAGGCGCCCT CAGCGCCCTG GGGGCCACCA
GCCGGGCCGC TCCACGTGCA GCTCTTCCCT TGCCTTTCGC CCCTACTGCT GGACGCGCGG
ACCCTGGACC CGCAGGGGGC GCCGCCGGCC GGCTGGGAAG TCTTCGACGT GTGGCAGGGC
CTGCGCCACC AGCCCTGGAA GCAGCTGTGC TTGGAGCTGC GGGCCGCATG GGGCGAGCTG
GACGCCGGGG AGGCCGAGGC GCGCGCGCGG GGACCCCAGC AACCGCCGCC CCCGGACCTG
CGGAGTCTGG GCTTCGGCCG GAGGGTGCGG CCTCCCCAGG AGCGGGCCCT GCTGGTGGTA
TTCACCAGAT CCCAGCGCAA GAACCTGTTC GCAGAGATGC GCGAGCAGCT GGGCTCGGCC
GAGGCTGCGG GCCCGGGCGC GGGCGCCGAG GGGTCGTGGC CGCCGCCGTC GGGCGCCCCG
GATGCCAGGC CTTGGCTGCC CTCGCCCGGC CGCCGGCGGC GGCGCACGGC CTTCGCCAGT
CGCCATGGCA AGCGGCACGG CAAGAAGTCC AGGCTACGCT GCAGCAAGAA GCCCCTGCAC
GTGAACTTCA AGGAGCTGGG CTGGGACGAC TGGATTATCG CGCCCCTGGA GTACGAGGCC
TATCACTGCG AGGGTGTATG CGACTTCCCG CTGCGCTCGC ACCTGGAGCC CACCAACCAC
GCCATCATCC AGACGCTGAT GAACTCCATG GACCCCGGCT CCACCCCGCC CAGCTGCTGC
GTGCCCACCA AATTGACTCC CATCAGCATT CTATACATCG ACGCGGGCAA TAATGTGGTC
TACAAGCAGT ACGAGGACAT GGTGGTGGAG TCGTGCGGCT GCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

A New Subtype of Multiple Synostoses Syndrome Is Caused by a Mutation in GDF6 That Decreases Its Sensitivity to Noggin and Enhances Its Potency as a BMP Signal.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research31(4)882-9(2016 Apr)
Wang J,Yu T,Wang Z,Ohte S,Yao RE,Zheng Z,Geng J,Cai H,Ge Y,Li Y,Xu Y,Zhang Q,Gusella JF,Fu Q,Pregizer S,Rosen V,Shen Y


book

Expression of growth differentiation factor 6 in the human developing fetal spine retreats from vertebral ossifying regions and is restricted to cartilaginous tissues.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society34(2)279-89(2016 Feb)
Wei A,Shen B,Williams LA,Bhargav D,Gulati T,Fang Z,Pathmanandavel S,Diwan AD


book

Localization of bone morphogenetic protein 13 in human intervertebral disc and its molecular and functional effects in vitro in 3D culture.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society33(12)1769-75(2015 Dec)
Gulati T,Chung SA,Wei AQ,Diwan AD


book

Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis.
Annals of the rheumatic diseases74(6)1249-56(2015 Jun)
Banka S,Cain SA,Carim S,Daly SB,Urquhart JE,Erdem G,Harris J,Bottomley M,Donnai D,Kerr B,Kingston H,Superti-Furga A,Unger S,Ennis H,Worthington J,Herrick AL,Merry CL,Yue WW,Kielty CM,Newman WG


book

Association of rs6982567 near GDF6 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Han Chinese cohort.
BMC ophthalmology14140(2014 Nov)
Ji Y,Zhang X,Wu K,Su Y,Li M,Zuo C,Wen F


 
*
*
*
*