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MEFV cDNA ORF clone, Homo sapiens (human)

Gene Symbol MEFV
Entrez Gene ID 4210
Full Name Mediterranean fever
Synonyms FMF, MEF, TRIM20
General protein information
Preferred Names
pyrin
Names
pyrin
marenostrin
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p13.3

Summary This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

608107

Disorder Html: Familial Mediterranean fever, AR, 249100 (3); Familial

mRNA and Protein(s)

mRNA Protein Name
NM_001198536 NP_001185465 pyrin isoform 2
NM_000243 NP_000234 pyrin isoform 1



Homo sapiens (human) MEFV NP_000234.1
Pan troglodytes (chimpanzee) MEFV XP_523280.3
Macaca mulatta (Rhesus monkey) MEFV XP_001092338.1
Canis lupus familiaris (dog) MEFV XP_547161.4
Bos taurus (cattle) LOC529195 XP_002697924.3
Mus musculus (house mouse) Mefv NP_001155263.1
Rattus norvegicus (Norway rat) Mefv NP_113822.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MEFV gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MEFV cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu21586 NM_001198536 Homo sapiens Mediterranean fever (MEFV), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $265.30
$379.00
OHu19174
NM_000243 Homo sapiens Mediterranean fever (MEFV), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu21586
Clone ID Related Accession (Same CDS sequence) NM_001198536
Accession Version NM_001198536.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1338bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pyrin isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF018080.1, FJ785722.1, Y14441.1 and AJ003147.1. Transcript Variant: This variant lacks an alternate in-frame exon and uses an alternate splice junction at the 5' end of an exon, that causes a frameshift. The resulting isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ785722.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA962336 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCTAAGA CCCCTAGTGA CCATCTGCTG TCCACCCTGG AGGAGCTGGT GCCCTATGAC 
TTCGAGAAGT TCAAGTTCAA GCTGCAGAAC ACCAGTGTGC AGAAGGAGCA CTCCAGGATC
CCCCGGAGCC AGATCCAGAG AGCCAGGCCG GTGAAGATGG CCACTCTGCT GGTCACCTAC
TATGGGGAAG AGTACGCCGT GCAGCTCACC CTGCAGGTCC TGCGGGCCAT CAACCAGCGC
CTGCTGGCCG AGGAGCTCCA CAGGGCAGCC ATTCAGGGAA GGCCACCAGA CACGGCTGCG
AGTCCCCGCT GCCACGCCCA GGAAGGAGAC CCAGTTGACG GTACCTGTGT GCGTGATTCC
TGCAGCTTCC CCGAGGCAGT TTCTGGGCAC CCCCAGGCCT CAGGCAGCCG CTCACCTGGC
TGCCCCCGGT GCCAGGACTC CCATGAAAGG AAGAGCCCGG GAAGCCTAAG CCCCCAGCCC
CTGCCACAGT GTAAGCGCCA CCTGAAGCAG GTCCAGCTGC TCTTCTGTGA GGATCACGAT
GAGCCCATCT GCCTCATCTG CAGTCTGAGT CAGGAGCACC AAGGCCACCG GGTGCGCCCC
ATTGAGGAGG TCGCCCTGGA ACACAAGAAG AAAATTCAGA AGCAGCTGGA GCATCTGAAG
AAGCTGAGAA AATCAGGGGA GGAGCAGCGA TCCTATGGGG AGGAGAAGGC AGTGAGCTTT
CTGAAACAAA CTGAAGCGCT GAAGCAGCGG GTGCAGAGGA AGCTGGAGCA GGTGTACTAC
TTCCTGGAGC AGCAAGAGCA TTTCTTTGTG GCCTCACTGG AGGACGTGGG CCAGATGGTT
GGGCAGATCA GGAAGGCATA TGACACCCGC GTATCCCAGG ACATCGCCCT GCTCGATGCG
CTGATTGGGG AACTGGAGGC CAAGGAGTGC CAGTCAGAAT GGGAACTTCT GCAGGACATT
GGAGACATCT TGCACAGGGC TAAGACAGTG CCTGTCCCTG AAAAGTGGAC CACTCCTCAA
GAGATAAAAC AAAAGATCCA ACTCCTCCAC CAGAAGTCAG AGTTTGTGGA GAAGAGCACA
AAGTACTTCT CAGAAACCCT GCGTTCAGAA ATGGAAATGT TCAATGACCA CAGTCCCCAA
CATGGCCTGG GTTCCTGGGA GGAACGGGAT TATACCCAAC ATAGCATGCA GGGCCCTAAG
CAGGGGGTTC CTTGTCTTTC CTTGTTGTCA GGACAGTGTA ATTTAGCCCC TCTTAATGCT
AATGCTCAGG ATTTTTTTCC CTATCTGATT TTTCTCCGTA GTTCCAGAGC TGATTGGCGC
TCAGGCACAT GCTGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001185465.1
CDS41..1378
Misc Feature(1)56..304(+)
Misc Feature(2)524..643(+)
Misc Feature(3)530..619(+)
Misc Feature(4)614..799(+)
Exon (1)1..317
Gene:MEFV
Gene Synonym:
Exon (2)318..667
Gene:MEFV
Gene Synonym:
Exon (3)668..763
Gene:MEFV
Gene Synonym:
Exon (4)764..994
Gene:MEFV
Gene Synonym:
Exon (5)995..1017
Gene:MEFV
Gene Synonym:
Exon (6)1018..1133
Gene:MEFV
Gene Synonym:
Exon (7)1134..1166
Gene:MEFV
Gene Synonym:
Exon (8)1167..1374
Gene:MEFV
Gene Synonym:
Exon (9)1375..3041
Gene:MEFV
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001198536
Organism Homo sapiens (human)
Definition Homo sapiens Mediterranean fever (MEFV), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001198536

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCTAAGA CCCCTAGTGA CCATCTGCTG TCCACCCTGG AGGAGCTGGT GCCCTATGAC 
TTCGAGAAGT TCAAGTTCAA GCTGCAGAAC ACCAGTGTGC AGAAGGAGCA CTCCAGGATC
CCCCGGAGCC AGATCCAGAG AGCCAGGCCG GTGAAGATGG CCACTCTGCT GGTCACCTAC
TATGGGGAAG AGTACGCCGT GCAGCTCACC CTGCAGGTCC TGCGGGCCAT CAACCAGCGC
CTGCTGGCCG AGGAGCTCCA CAGGGCAGCC ATTCAGGGAA GGCCACCAGA CACGGCTGCG
AGTCCCCGCT GCCACGCCCA GGAAGGAGAC CCAGTTGACG GTACCTGTGT GCGTGATTCC
TGCAGCTTCC CCGAGGCAGT TTCTGGGCAC CCCCAGGCCT CAGGCAGCCG CTCACCTGGC
TGCCCCCGGT GCCAGGACTC CCATGAAAGG AAGAGCCCGG GAAGCCTAAG CCCCCAGCCC
CTGCCACAGT GTAAGCGCCA CCTGAAGCAG GTCCAGCTGC TCTTCTGTGA GGATCACGAT
GAGCCCATCT GCCTCATCTG CAGTCTGAGT CAGGAGCACC AAGGCCACCG GGTGCGCCCC
ATTGAGGAGG TCGCCCTGGA ACACAAGAAG AAAATTCAGA AGCAGCTGGA GCATCTGAAG
AAGCTGAGAA AATCAGGGGA GGAGCAGCGA TCCTATGGGG AGGAGAAGGC AGTGAGCTTT
CTGAAACAAA CTGAAGCGCT GAAGCAGCGG GTGCAGAGGA AGCTGGAGCA GGTGTACTAC
TTCCTGGAGC AGCAAGAGCA TTTCTTTGTG GCCTCACTGG AGGACGTGGG CCAGATGGTT
GGGCAGATCA GGAAGGCATA TGACACCCGC GTATCCCAGG ACATCGCCCT GCTCGATGCG
CTGATTGGGG AACTGGAGGC CAAGGAGTGC CAGTCAGAAT GGGAACTTCT GCAGGACATT
GGAGACATCT TGCACAGGGC TAAGACAGTG CCTGTCCCTG AAAAGTGGAC CACTCCTCAA
GAGATAAAAC AAAAGATCCA ACTCCTCCAC CAGAAGTCAG AGTTTGTGGA GAAGAGCACA
AAGTACTTCT CAGAAACCCT GCGTTCAGAA ATGGAAATGT TCAATGACCA CAGTCCCCAA
CATGGCCTGG GTTCCTGGGA GGAACGGGAT TATACCCAAC ATAGCATGCA GGGCCCTAAG
CAGGGGGTTC CTTGTCTTTC CTTGTTGTCA GGACAGTGTA ATTTAGCCCC TCTTAATGCT
AATGCTCAGG ATTTTTTTCC CTATCTGATT TTTCTCCGTA GTTCCAGAGC TGATTGGCGC
TCAGGCACAT GCTGTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19174
Clone ID Related Accession (Same CDS sequence) NM_000243
Accession Version NM_000243.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2346bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pyrin isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF018080.1 and AJ003147.1. This sequence is a reference standard in the RefSeqGene project. On May 15, 2008 this sequence version replaced gi:4557742. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF018080.1, Y14441.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTAAGA CCCCTAGTGA CCATCTGCTG TCCACCCTGG AGGAGCTGGT GCCCTATGAC 
TTCGAGAAGT TCAAGTTCAA GCTGCAGAAC ACCAGTGTGC AGAAGGAGCA CTCCAGGATC
CCCCGGAGCC AGATCCAGAG AGCCAGGCCG GTGAAGATGG CCACTCTGCT GGTCACCTAC
TATGGGGAAG AGTACGCCGT GCAGCTCACC CTGCAGGTCC TGCGGGCCAT CAACCAGCGC
CTGCTGGCCG AGGAGCTCCA CAGGGCAGCC ATTCAGGAAT ATTCCACACA AGAAAACGGC
ACAGATGATT CCGCAGCGTC CAGCTCCCTG GGGGAGAACA AGCCCAGGAG CCTGAAGACT
CCAGACCACC CCGAGGGGAA CGAGGGGAAC GGCCCTCGGC CGTACGGGGG CGGAGCTGCC
AGCCTGCGGT GCAGCCAGCC CGAGGCCGGG AGGGGGCTGT CGAGGAAGCC CCTGAGCAAA
CGCAGAGAGA AGGCCTCGGA GGGCCTGGAC GCGCAGGGCA AGCCTCGGAC CCGGAGCCCG
GCCCTGCCGG GCGGGAGAAG CCCCGGCCCC TGCAGGGCGC TAGAGGGGGG CCAGGCCGAG
GTCCGGCTGC GCAGAAACGC CAGCTCCGCG GGGAGGCTGC AGGGGCTGGC GGGGGGCGCC
CCGGGGCAGA AGGAGTGCAG GCCCTTCGAA GTGTACCTGC CCTCGGGAAA GATGCGACCT
AGAAGCCTTG AGGTCACCAT TTCTACAGGG GAGAAGGCGC CCGCAAATCC AGAAATTCTC
CTGACTCTAG AGGAAAAGAC AGCTGCGAAT CTGGACTCGG CAACAGAACC CCGGGCAAGG
CCCACTCCGG ATGGAGGGGC ATCTGCGGAC CTGAAGGAAG GCCCTGGAAA TCCAGAACAT
TCGGTCACCG GAAGGCCACC AGACACGGCT GCGAGTCCCC GCTGCCACGC CCAGGAAGGA
GACCCAGTTG ACGGTACCTG TGTGCGTGAT TCCTGCAGCT TCCCCGAGGC AGTTTCTGGG
CACCCCCAGG CCTCAGGCAG CCGCTCACCT GGCTGCCCCC GGTGCCAGGA CTCCCATGAA
AGGAAGAGCC CGGGAAGCCT AAGCCCCCAG CCCCTGCCAC AGTGTAAGCG CCACCTGAAG
CAGGTCCAGC TGCTCTTCTG TGAGGATCAC GATGAGCCCA TCTGCCTCAT CTGCAGTCTG
AGTCAGGAGC ACCAAGGCCA CCGGGTGCGC CCCATTGAGG AGGTCGCCCT GGAACACAAG
AAGAAAATTC AGAAGCAGCT GGAGCATCTG AAGAAGCTGA GAAAATCAGG GGAGGAGCAG
CGATCCTATG GGGAGGAGAA GGCAGTGAGC TTTCTGAAAC AAACTGAAGC GCTGAAGCAG
CGGGTGCAGA GGAAGCTGGA GCAGGTGTAC TACTTCCTGG AGCAGCAAGA GCATTTCTTT
GTGGCCTCAC TGGAGGACGT GGGCCAGATG GTTGGGCAGA TCAGGAAGGC ATATGACACC
CGCGTATCCC AGGACATCGC CCTGCTCGAT GCGCTGATTG GGGAACTGGA GGCCAAGGAG
TGCCAGTCAG AATGGGAACT TCTGCAGGAC ATTGGAGACA TCTTGCACAG GGCTAAGACA
GTGCCTGTCC CTGAAAAGTG GACCACTCCT CAAGAGATAA AACAAAAGAT CCAACTCCTC
CACCAGAAGT CAGAGTTTGT GGAGAAGAGC ACAAAGTACT TCTCAGAAAC CCTGCGTTCA
GAAATGGAAA TGTTCAATGT TCCAGAGCTG ATTGGCGCTC AGGCACATGC TGTTAATGTG
ATTCTGGATG CAGAAACCGC TTACCCCAAC CTCATCTTCT CTGATGATCT GAAGAGTGTT
AGACTTGGAA ACAAGTGGGA GAGGCTGCCT GATGGCCCGC AAAGATTTGA CAGCTGTATC
ATTGTTCTGG GCTCTCCGAG TTTCCTCTCT GGCCGCCGTT ACTGGGAGGT GGAGGTTGGA
GACAAGACAG CATGGATCCT GGGAGCCTGC AAGACATCCA TAAGCAGGAA AGGGAACATG
ACTCTGTCGC CAGAGAATGG CTACTGGGTG GTGATAATGA TGAAGGAAAA TGAGTACCAG
GCGTCCAGCG TTCCCCCGAC CCGCCTGCTA ATAAAGGAGC CTCCCAAGCG TGTGGGCATC
TTCGTGGACT ACAGAGTTGG AAGCATCTCC TTTTACAATG TGACAGCCAG ATCCCACATC
TATACATTCG CCAGCTGCTC TTTCTCTGGG CCCCTTCAAC CTATCTTCAG CCCTGGGACA
CGTGATGGAG GGAAGAACAC AGCTCCTCTG ACTATCTGTC CAGTGGGTGG TCAGGGGCCT
GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000234.1
CDS41..2386
Misc Feature(1)56..304(+)
Misc Feature(2)836..880(+)
Misc Feature(3)1028..1033(+)
Misc Feature(4)1157..1276(+)
Misc Feature(5)1163..1252(+)
Misc Feature(6)1247..1432(+)
Misc Feature(7)1298..1786(+)
Misc Feature(8)1298..1351(+)
Misc Feature(9)1826..2359(+)
Exon (1)1..317
Gene:MEFV
Gene Synonym:
Exon (2)318..950
Gene:MEFV
Gene Synonym:
Exon (3)951..1300
Gene:MEFV
Gene Synonym:
Exon (4)1301..1396
Gene:MEFV
Gene Synonym:
Exon (5)1397..1627
Gene:MEFV
Gene Synonym:
Exon (6)1628..1650
Gene:MEFV
Gene Synonym:
Exon (7)1651..1766
Gene:MEFV
Gene Synonym:
Exon (8)1767..1799
Gene:MEFV
Gene Synonym:
Exon (9)1800..1832
Gene:MEFV
Gene Synonym:
Exon (10)1833..3499
Gene:MEFV
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000243
Organism Homo sapiens (human)
Definition Homo sapiens Mediterranean fever (MEFV), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000243

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTAAGA CCCCTAGTGA CCATCTGCTG TCCACCCTGG AGGAGCTGGT GCCCTATGAC 
TTCGAGAAGT TCAAGTTCAA GCTGCAGAAC ACCAGTGTGC AGAAGGAGCA CTCCAGGATC
CCCCGGAGCC AGATCCAGAG AGCCAGGCCG GTGAAGATGG CCACTCTGCT GGTCACCTAC
TATGGGGAAG AGTACGCCGT GCAGCTCACC CTGCAGGTCC TGCGGGCCAT CAACCAGCGC
CTGCTGGCCG AGGAGCTCCA CAGGGCAGCC ATTCAGGAAT ATTCCACACA AGAAAACGGC
ACAGATGATT CCGCAGCGTC CAGCTCCCTG GGGGAGAACA AGCCCAGGAG CCTGAAGACT
CCAGACCACC CCGAGGGGAA CGAGGGGAAC GGCCCTCGGC CGTACGGGGG CGGAGCTGCC
AGCCTGCGGT GCAGCCAGCC CGAGGCCGGG AGGGGGCTGT CGAGGAAGCC CCTGAGCAAA
CGCAGAGAGA AGGCCTCGGA GGGCCTGGAC GCGCAGGGCA AGCCTCGGAC CCGGAGCCCG
GCCCTGCCGG GCGGGAGAAG CCCCGGCCCC TGCAGGGCGC TAGAGGGGGG CCAGGCCGAG
GTCCGGCTGC GCAGAAACGC CAGCTCCGCG GGGAGGCTGC AGGGGCTGGC GGGGGGCGCC
CCGGGGCAGA AGGAGTGCAG GCCCTTCGAA GTGTACCTGC CCTCGGGAAA GATGCGACCT
AGAAGCCTTG AGGTCACCAT TTCTACAGGG GAGAAGGCGC CCGCAAATCC AGAAATTCTC
CTGACTCTAG AGGAAAAGAC AGCTGCGAAT CTGGACTCGG CAACAGAACC CCGGGCAAGG
CCCACTCCGG ATGGAGGGGC ATCTGCGGAC CTGAAGGAAG GCCCTGGAAA TCCAGAACAT
TCGGTCACCG GAAGGCCACC AGACACGGCT GCGAGTCCCC GCTGCCACGC CCAGGAAGGA
GACCCAGTTG ACGGTACCTG TGTGCGTGAT TCCTGCAGCT TCCCCGAGGC AGTTTCTGGG
CACCCCCAGG CCTCAGGCAG CCGCTCACCT GGCTGCCCCC GGTGCCAGGA CTCCCATGAA
AGGAAGAGCC CGGGAAGCCT AAGCCCCCAG CCCCTGCCAC AGTGTAAGCG CCACCTGAAG
CAGGTCCAGC TGCTCTTCTG TGAGGATCAC GATGAGCCCA TCTGCCTCAT CTGCAGTCTG
AGTCAGGAGC ACCAAGGCCA CCGGGTGCGC CCCATTGAGG AGGTCGCCCT GGAACACAAG
AAGAAAATTC AGAAGCAGCT GGAGCATCTG AAGAAGCTGA GAAAATCAGG GGAGGAGCAG
CGATCCTATG GGGAGGAGAA GGCAGTGAGC TTTCTGAAAC AAACTGAAGC GCTGAAGCAG
CGGGTGCAGA GGAAGCTGGA GCAGGTGTAC TACTTCCTGG AGCAGCAAGA GCATTTCTTT
GTGGCCTCAC TGGAGGACGT GGGCCAGATG GTTGGGCAGA TCAGGAAGGC ATATGACACC
CGCGTATCCC AGGACATCGC CCTGCTCGAT GCGCTGATTG GGGAACTGGA GGCCAAGGAG
TGCCAGTCAG AATGGGAACT TCTGCAGGAC ATTGGAGACA TCTTGCACAG GGCTAAGACA
GTGCCTGTCC CTGAAAAGTG GACCACTCCT CAAGAGATAA AACAAAAGAT CCAACTCCTC
CACCAGAAGT CAGAGTTTGT GGAGAAGAGC ACAAAGTACT TCTCAGAAAC CCTGCGTTCA
GAAATGGAAA TGTTCAATGT TCCAGAGCTG ATTGGCGCTC AGGCACATGC TGTTAATGTG
ATTCTGGATG CAGAAACCGC TTACCCCAAC CTCATCTTCT CTGATGATCT GAAGAGTGTT
AGACTTGGAA ACAAGTGGGA GAGGCTGCCT GATGGCCCGC AAAGATTTGA CAGCTGTATC
ATTGTTCTGG GCTCTCCGAG TTTCCTCTCT GGCCGCCGTT ACTGGGAGGT GGAGGTTGGA
GACAAGACAG CATGGATCCT GGGAGCCTGC AAGACATCCA TAAGCAGGAA AGGGAACATG
ACTCTGTCGC CAGAGAATGG CTACTGGGTG GTGATAATGA TGAAGGAAAA TGAGTACCAG
GCGTCCAGCG TTCCCCCGAC CCGCCTGCTA ATAAAGGAGC CTCCCAAGCG TGTGGGCATC
TTCGTGGACT ACAGAGTTGG AAGCATCTCC TTTTACAATG TGACAGCCAG ATCCCACATC
TATACATTCG CCAGCTGCTC TTTCTCTGGG CCCCTTCAAC CTATCTTCAG CCCTGGGACA
CGTGATGGAG GGAAGAACAC AGCTCCTCTG ACTATCTGTC CAGTGGGTGG TCAGGGGCCT
GACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Three Japanese patients (mother and two children) with familial Mediterranean fever associated with compound heterozygosity for L110P/E148Q/M694I and an autosomal true dominant inheritance pattern
Asian Pac. J. Allergy Immunol. 31 (4), 325-329 (2013)
Fukushima Y, Obara K, Hirata H, Sugiyama K, Fukuda T and Takabe K.


book

The presence of MEFV gene mutations in patients with primary osteoarthritis who require surgery
Korean J. Intern. Med. 28 (5), 594-598 (2013)
Yilmaz S, Erdem H, Tunay S, Torun D, Genc H, Tunca Y, Karadag O, Simsek I, Bahce M, Pay S and Dinc A.


book

MEFV gene mutations in Henoch-Schonlein purpura
Int J Rheum Dis 16 (3), 347-351 (2013)
Altug U, Ensari C, Sayin DB and Ensari A.


book

MEFV gene mutations and their clinical significance in Korean patients with adult-onset Still's disease
Clin. Exp. Rheumatol. 31 (3 SUPPL 77), 60-63 (2013)
Kim JJ, Kim JK, Shim SC, Choe JY, Kim TH, Jun JB and Yoo DH.


book

Expression of the familial Mediterranean fever gene is regulated by nonsense-mediated decay
Hum. Mol. Genet. 18 (24), 4746-4755 (2009)
Grandemange S, Soler S and Touitou I.


book

A transcriptional Map of the FMF region
Genomics 50 (2), 147-160 (1998)
Bernot A, Heilig R, Clepet C, Smaoui N, Da Silva C, Petit JL, Devaud C, Chiannilkulchai N, Fizames C, Samson D, Cruaud C, Caloustian C, Gyapay G, Delpech M and Weissenbach J.


book

Familial Mediterranean fever: from the clinical syndrome to the cloning of the pyrin gene
Scand. J. Rheumatol. 27 (2), 92-97 (1998)
Pras,M.


book

Construction of a 1-Mb restriction-mapped cosmid contig containing the candidate region for the familial Mediterranean fever locus (MEFV) on chromosome 16p 13.3
Genomics 42 (1), 83-95 (1997)
Sood R, Blake T, Aksentijevich I, Wood G, Chen X, Gardner D, Shelton DA, Mangelsdorf M, Orsborn A, Pras E, Balow JE Jr, Centola M, Deng Z, Zaks N, Chen X, Richards N, Fischel-Ghodsian N, Rotter JI, Pras M, Shohat M, Deaven LL, Gumucio DL, Callen DF, Richards RI and Doggett NA.


book

Genotypic diagnosis of familial Mediterranean fever (FMF) using new microsatellite markers: example of two extensive non-Ashkenazi Jewish pedigrees
J. Med. Genet. 34 (5), 375-381 (1997)
Dupont M, Dross C, Smaoui N, Nedelec B, Grateau G, Clepet C, Gourdier I, Kone-Paut I, Delpech M, Demaille J and Touitou I.


book

Familial Mediterranean Fever
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Shohat,M. and Halpern,G.J.


 
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