| Gene Symbol | NFKBIA |
| Entrez Gene ID | 4792 |
| Full Name | NFKB inhibitor alpha |
| Synonyms | IKBA,MAD-3,NFKBI |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]. |
| Disorder MIM: | |
| Disorder Html: | Ectodermal dysplasia, anhidrotic, with T-cell immunodeficiency, 612132 (3) |

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