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ADAM17 cDNA ORF clone, Homo sapiens (human)

Gene Symbol ADAM17
Entrez Gene ID 6868
Full Name ADAM metallopeptidase domain 17
Synonyms ADAM18, CD156B, CSVP, NISBD, NISBD1, TACE
General protein information
Preferred Names
disintegrin and metalloproteinase domain-containing protein 17
Names
disintegrin and metalloproteinase domain-containing protein 17
TNF-alpha convertase
snake venom-like protease
TNF-alpha converting enzyme
ADAM metallopeptidase domain 18
tumor necrosis factor, alpha, converting enzyme
NP_003174.3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p25

Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

603639


mRNA and Protein(s)

mRNA Protein Name
XM_011510375 XP_011508677 disintegrin and metalloproteinase domain-containing protein 17 isoform X1
XM_011510376 XP_011508678 disintegrin and metalloproteinase domain-containing protein 17 isoform X2
XM_011510377 XP_011508679 disintegrin and metalloproteinase domain-containing protein 17 isoform X3
XM_011510378 XP_011508680 disintegrin and metalloproteinase domain-containing protein 17 isoform X3
NM_003183 NP_003174 disintegrin and metalloproteinase domain-containing protein 17 preproprotein



Homo sapiens (human) ADAM17 NP_003174.3
Pan troglodytes (chimpanzee) ADAM17 XP_515293.2
Macaca mulatta (Rhesus monkey) ADAM17 XP_002799185.1
Canis lupus familiaris (dog) ADAM17 XP_005630166.1
Bos taurus (cattle) ADAM17 XP_002691532.1
Mus musculus (house mouse) Adam17 NP_033745.4
Rattus norvegicus (Norway rat) Adam17 NP_064702.1
Gallus gallus (chicken) ADAM17 NP_001008682.1
Danio rerio (zebrafish) adam17a NP_955967.1
Danio rerio (zebrafish) adam17b XP_689147.3
Drosophila melanogaster (fruit fly) Tace NP_733334.1
Caenorhabditis elegans adm-4 NP_509318.1
Xenopus (Silurana) tropicalis (western clawed frog) adam17 NP_001182159.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ADAM17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAM17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu60843 XM_011510375 PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu60844 XM_011510376 PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
OHu60845 XM_011510377 PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
OHu60845 XM_011510378 PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
OHu21940 NM_003183 Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $391.30
$559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu60843
Clone ID Related Accession (Same CDS sequence) XM_011510375
Accession Version XM_011510375.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2382bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product disintegrin and metalloproteinase domain-containing protein 17 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005334.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGAAGAAGC TTGATTCTTT GCTCTCAGAC TACGATATTC TCTCTTTATC TAATATCCAG 
CAGCATTCGG TAAGAAAAAG AGATCTACAG ACTTCAACAC ATGTAGAAAC ACTACTAACT
TTTTCAGCTT TGAAAAGGCA TTTTAAATTA TACCTGACAT CAAGTACTGA ACGTTTTTCA
CAAAATTTCA AGGTCGTGGT GGTGGATGGT AAAAACGAAA GCGAGTACAC TGTAAAATGG
CAGGACTTCT TCACTGGACA CGTGGTTGGT GAGCCTGACT CTAGGGTTCT AGCCCACATA
AGAGATGATG ATGTTATAAT CAGAATCAAC ACAGATGGGG CCGAATATAA CATAGAGCCA
CTTTGGAGAT TTGTTAATGA TACCAAAGAC AAAAGAATGT TAGTTTATAA ATCTGAAGAT
ATCAAGAATG TTTCACGTTT GCAGTCTCCA AAAGTGTGTG GTTATTTAAA AGTGGATAAT
GAAGAGTTGC TCCCAAAAGG GTTAGTAGAC AGAGAACCAC CTGAAGAGCT TGTTCATCGA
GTGAAAAGAA GAGCTGACCC AGATCCCATG AAGAACACGT GTAAATTATT GGTGGTAGCA
GATCATCGCT TCTACAGATA CATGGGCAGA GGGGAAGAGA GTACAACTAC AAATTACTTA
ATAGAGCTAA TTGACAGAGT TGATGACATC TATCGGAACA CTTCATGGGA TAATGCAGGT
TTTAAAGGCT ATGGAATACA GATAGAGCAG ATTCGCATTC TCAAGTCTCC ACAAGAGGTA
AAACCTGGTG AAAAGCACTA CAACATGGCA AAAAGTTACC CAAATGAAGA AAAGGATGCT
TGGGATGTGA AGATGTTGCT AGAGCAATTT AGCTTTGATA TAGCTGAGGA AGCATCTAAA
GTTTGCTTGG CACACCTTTT CACATACCAA GATTTTGATA TGGGAACTCT TGGATTAGCT
TATGTTGGCT CTCCCAGAGC AAACAGCCAT GGAGGTGTTT GTCCAAAGGC TTATTATAGC
CCAGTTGGGA AGAAAAATAT CTATTTGAAT AGTGGTTTGA CGAGCACAAA GAATTATGGT
AAAACCATCC TTACAAAGGA AGCTGACCTG GTTACAACTC ATGAATTGGG ACATAATTTT
GGAGCAGAAC ATGATCCGGA TGGTCTAGCA GAATGTGCCC CGAATGAGGA CCAGGGAGGG
AAATATGTCA TGTATCCCAT AGCTGTGAGT GGCGATCACG AGAACAATAA GATGTTTTCA
AACTGCAGTA AACAATCAAT CTATAAGACC ATTGAAAGTA AGGCCCAGGA GTGTTTTCAA
GAACGCAGCA ATAAAGTTTG TGGGAACTCG AGGGTGGATG AAGGAGAAGA GTGTGATCCT
GGCATCATGT ATCTGAACAA CGACACCTGC TGCAACAGCG ACTGCACGTT GAAGGAAGGT
GTCCAGTGCA GTGACAGGAA CAGTCCTTGC TGTAAAAACT GTCAGTTTGA GACTGCCCAG
AAGAAGTGCC AGGAGGCGAT TAATGCTACT TGCAAAGGCG TGTCCTACTG CACAGGTAAT
AGCAGTGAGT GCCCGCCTCC AGGAAATGCT GAAGATGACA CTGTTTGCTT GGATCTTGGC
AAGTGTAAGG ATGGGAAATG CATCCCTTTC TGCGAGAGGG AACAGCAGCT GGAGTCCTGT
GCATGTAATG AAACTGACAA CTCCTGCAAG GTGTGCTGCA GGGACCTTTC TGGCCGCTGT
GTGCCCTATG TCGATGCTGA ACAAAAGAAC TTATTTTTGA GGAAAGGAAA GCCCTGTACA
GTAGGATTTT GTGACATGAA TGGCAAATGT GAGAAACGAG TACAGGATGT AATTGAACGA
TTTTGGGATT TCATTGACCA GCTGAGCATC AATACTTTTG GAAAGTTTTT AGCAGACAAC
ATCGTTGGGT CTGTCCTGGT TTTCTCCTTG ATATTTTGGA TTCCTTTCAG CATTCTTGTC
CATTGTGTGG ATAAGAAATT GGATAAACAG TATGAATCTC TGTCTCTGTT TCACCCCAGT
AACGTCGAAA TGCTGAGCAG CATGGATTCT GCATCGGTTC GCATTATCAA ACCCTTTCCT
GCGCCCCAGA CTCCAGGCCG CCTGCAGCCT GCCCCTGTGA TCCCTTCGGC GCCAGCAGCT
CCAAAACTGG ACCACCAGAG AATGGACACC ATCCAGGAAG ACCCCAGCAC AGACTCACAT
ATGGACGAGG ATGGGTTTGA GAAGGACCCC TTCCCAAATA GCAGCACAGC TGCCAAGTCA
TTTGAGGATC TCACGGACCA TCCGGTCACC AGAAGTGAAA AGGCTGCCTC CTTTAAACTG
CAGCGTCAGA ATCGTGTTGA CAGCAAAGAA ACAGAGTGCT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011508677.1
CDS31..2412
Misc Feature(1)61..438(+)
Misc Feature(2)604..1368(+)
Misc Feature(3)1150..1182(+)
Misc Feature(4)1387..1617(+)
Misc Feature(5)1675..1863(+)
Misc Feature(6)1735..1842(+)
Misc Feature(7)1735..1746(+)
Translation

Target ORF information:

RefSeq Version XM_011510375
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011510375

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGAAGAAGC TTGATTCTTT GCTCTCAGAC TACGATATTC TCTCTTTATC TAATATCCAG 
CAGCATTCGG TAAGAAAAAG AGATCTACAG ACTTCAACAC ATGTAGAAAC ACTACTAACT
TTTTCAGCTT TGAAAAGGCA TTTTAAATTA TACCTGACAT CAAGTACTGA ACGTTTTTCA
CAAAATTTCA AGGTCGTGGT GGTGGATGGT AAAAACGAAA GCGAGTACAC TGTAAAATGG
CAGGACTTCT TCACTGGACA CGTGGTTGGT GAGCCTGACT CTAGGGTTCT AGCCCACATA
AGAGATGATG ATGTTATAAT CAGAATCAAC ACAGATGGGG CCGAATATAA CATAGAGCCA
CTTTGGAGAT TTGTTAATGA TACCAAAGAC AAAAGAATGT TAGTTTATAA ATCTGAAGAT
ATCAAGAATG TTTCACGTTT GCAGTCTCCA AAAGTGTGTG GTTATTTAAA AGTGGATAAT
GAAGAGTTGC TCCCAAAAGG GTTAGTAGAC AGAGAACCAC CTGAAGAGCT TGTTCATCGA
GTGAAAAGAA GAGCTGACCC AGATCCCATG AAGAACACGT GTAAATTATT GGTGGTAGCA
GATCATCGCT TCTACAGATA CATGGGCAGA GGGGAAGAGA GTACAACTAC AAATTACTTA
ATAGAGCTAA TTGACAGAGT TGATGACATC TATCGGAACA CTTCATGGGA TAATGCAGGT
TTTAAAGGCT ATGGAATACA GATAGAGCAG ATTCGCATTC TCAAGTCTCC ACAAGAGGTA
AAACCTGGTG AAAAGCACTA CAACATGGCA AAAAGTTACC CAAATGAAGA AAAGGATGCT
TGGGATGTGA AGATGTTGCT AGAGCAATTT AGCTTTGATA TAGCTGAGGA AGCATCTAAA
GTTTGCTTGG CACACCTTTT CACATACCAA GATTTTGATA TGGGAACTCT TGGATTAGCT
TATGTTGGCT CTCCCAGAGC AAACAGCCAT GGAGGTGTTT GTCCAAAGGC TTATTATAGC
CCAGTTGGGA AGAAAAATAT CTATTTGAAT AGTGGTTTGA CGAGCACAAA GAATTATGGT
AAAACCATCC TTACAAAGGA AGCTGACCTG GTTACAACTC ATGAATTGGG ACATAATTTT
GGAGCAGAAC ATGATCCGGA TGGTCTAGCA GAATGTGCCC CGAATGAGGA CCAGGGAGGG
AAATATGTCA TGTATCCCAT AGCTGTGAGT GGCGATCACG AGAACAATAA GATGTTTTCA
AACTGCAGTA AACAATCAAT CTATAAGACC ATTGAAAGTA AGGCCCAGGA GTGTTTTCAA
GAACGCAGCA ATAAAGTTTG TGGGAACTCG AGGGTGGATG AAGGAGAAGA GTGTGATCCT
GGCATCATGT ATCTGAACAA CGACACCTGC TGCAACAGCG ACTGCACGTT GAAGGAAGGT
GTCCAGTGCA GTGACAGGAA CAGTCCTTGC TGTAAAAACT GTCAGTTTGA GACTGCCCAG
AAGAAGTGCC AGGAGGCGAT TAATGCTACT TGCAAAGGCG TGTCCTACTG CACAGGTAAT
AGCAGTGAGT GCCCGCCTCC AGGAAATGCT GAAGATGACA CTGTTTGCTT GGATCTTGGC
AAGTGTAAGG ATGGGAAATG CATCCCTTTC TGCGAGAGGG AACAGCAGCT GGAGTCCTGT
GCATGTAATG AAACTGACAA CTCCTGCAAG GTGTGCTGCA GGGACCTTTC TGGCCGCTGT
GTGCCCTATG TCGATGCTGA ACAAAAGAAC TTATTTTTGA GGAAAGGAAA GCCCTGTACA
GTAGGATTTT GTGACATGAA TGGCAAATGT GAGAAACGAG TACAGGATGT AATTGAACGA
TTTTGGGATT TCATTGACCA GCTGAGCATC AATACTTTTG GAAAGTTTTT AGCAGACAAC
ATCGTTGGGT CTGTCCTGGT TTTCTCCTTG ATATTTTGGA TTCCTTTCAG CATTCTTGTC
CATTGTGTGG ATAAGAAATT GGATAAACAG TATGAATCTC TGTCTCTGTT TCACCCCAGT
AACGTCGAAA TGCTGAGCAG CATGGATTCT GCATCGGTTC GCATTATCAA ACCCTTTCCT
GCGCCCCAGA CTCCAGGCCG CCTGCAGCCT GCCCCTGTGA TCCCTTCGGC GCCAGCAGCT
CCAAAACTGG ACCACCAGAG AATGGACACC ATCCAGGAAG ACCCCAGCAC AGACTCACAT
ATGGACGAGG ATGGGTTTGA GAAGGACCCC TTCCCAAATA GCAGCACAGC TGCCAAGTCA
TTTGAGGATC TCACGGACCA TCCGGTCACC AGAAGTGAAA AGGCTGCCTC CTTTAAACTG
CAGCGTCAGA ATCGTGTTGA CAGCAAAGAA ACAGAGTGCT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60844
Clone ID Related Accession (Same CDS sequence) XM_011510376
Accession Version XM_011510376.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1815bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product disintegrin and metalloproteinase domain-containing protein 17 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005334.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGAAGAACA CGTGTAAATT ATTGGTGGTA GCAGATCATC GCTTCTACAG ATACATGGGC 
AGAGGGGAAG AGAGTACAAC TACAAATTAC TTAATAGAGC TAATTGACAG AGTTGATGAC
ATCTATCGGA ACACTTCATG GGATAATGCA GGTTTTAAAG GCTATGGAAT ACAGATAGAG
CAGATTCGCA TTCTCAAGTC TCCACAAGAG GTAAAACCTG GTGAAAAGCA CTACAACATG
GCAAAAAGTT ACCCAAATGA AGAAAAGGAT GCTTGGGATG TGAAGATGTT GCTAGAGCAA
TTTAGCTTTG ATATAGCTGA GGAAGCATCT AAAGTTTGCT TGGCACACCT TTTCACATAC
CAAGATTTTG ATATGGGAAC TCTTGGATTA GCTTATGTTG GCTCTCCCAG AGCAAACAGC
CATGGAGGTG TTTGTCCAAA GGCTTATTAT AGCCCAGTTG GGAAGAAAAA TATCTATTTG
AATAGTGGTT TGACGAGCAC AAAGAATTAT GGTAAAACCA TCCTTACAAA GGAAGCTGAC
CTGGTTACAA CTCATGAATT GGGACATAAT TTTGGAGCAG AACATGATCC GGATGGTCTA
GCAGAATGTG CCCCGAATGA GGACCAGGGA GGGAAATATG TCATGTATCC CATAGCTGTG
AGTGGCGATC ACGAGAACAA TAAGATGTTT TCAAACTGCA GTAAACAATC AATCTATAAG
ACCATTGAAA GTAAGGCCCA GGAGTGTTTT CAAGAACGCA GCAATAAAGT TTGTGGGAAC
TCGAGGGTGG ATGAAGGAGA AGAGTGTGAT CCTGGCATCA TGTATCTGAA CAACGACACC
TGCTGCAACA GCGACTGCAC GTTGAAGGAA GGTGTCCAGT GCAGTGACAG GAACAGTCCT
TGCTGTAAAA ACTGTCAGTT TGAGACTGCC CAGAAGAAGT GCCAGGAGGC GATTAATGCT
ACTTGCAAAG GCGTGTCCTA CTGCACAGGT AATAGCAGTG AGTGCCCGCC TCCAGGAAAT
GCTGAAGATG ACACTGTTTG CTTGGATCTT GGCAAGTGTA AGGATGGGAA ATGCATCCCT
TTCTGCGAGA GGGAACAGCA GCTGGAGTCC TGTGCATGTA ATGAAACTGA CAACTCCTGC
AAGGTGTGCT GCAGGGACCT TTCTGGCCGC TGTGTGCCCT ATGTCGATGC TGAACAAAAG
AACTTATTTT TGAGGAAAGG AAAGCCCTGT ACAGTAGGAT TTTGTGACAT GAATGGCAAA
TGTGAGAAAC GAGTACAGGA TGTAATTGAA CGATTTTGGG ATTTCATTGA CCAGCTGAGC
ATCAATACTT TTGGAAAGTT TTTAGCAGAC AACATCGTTG GGTCTGTCCT GGTTTTCTCC
TTGATATTTT GGATTCCTTT CAGCATTCTT GTCCATTGTG TGGATAAGAA ATTGGATAAA
CAGTATGAAT CTCTGTCTCT GTTTCACCCC AGTAACGTCG AAATGCTGAG CAGCATGGAT
TCTGCATCGG TTCGCATTAT CAAACCCTTT CCTGCGCCCC AGACTCCAGG CCGCCTGCAG
CCTGCCCCTG TGATCCCTTC GGCGCCAGCA GCTCCAAAAC TGGACCACCA GAGAATGGAC
ACCATCCAGG AAGACCCCAG CACAGACTCA CATATGGACG AGGATGGGTT TGAGAAGGAC
CCCTTCCCAA ATAGCAGCAC AGCTGCCAAG TCATTTGAGG ATCTCACGGA CCATCCGGTC
ACCAGAAGTG AAAAGGCTGC CTCCTTTAAA CTGCAGCGTC AGAATCGTGT TGACAGCAAA
GAAACAGAGT GCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011508678.1
CDS188..2002
Misc Feature(1)194..958(+)
Misc Feature(2)740..772(+)
Misc Feature(3)977..1207(+)
Misc Feature(4)1265..1453(+)
Misc Feature(5)1325..1432(+)
Misc Feature(6)1325..1336(+)
Translation

Target ORF information:

RefSeq Version XM_011510376
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011510376

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGAAGAACA CGTGTAAATT ATTGGTGGTA GCAGATCATC GCTTCTACAG ATACATGGGC 
AGAGGGGAAG AGAGTACAAC TACAAATTAC TTAATAGAGC TAATTGACAG AGTTGATGAC
ATCTATCGGA ACACTTCATG GGATAATGCA GGTTTTAAAG GCTATGGAAT ACAGATAGAG
CAGATTCGCA TTCTCAAGTC TCCACAAGAG GTAAAACCTG GTGAAAAGCA CTACAACATG
GCAAAAAGTT ACCCAAATGA AGAAAAGGAT GCTTGGGATG TGAAGATGTT GCTAGAGCAA
TTTAGCTTTG ATATAGCTGA GGAAGCATCT AAAGTTTGCT TGGCACACCT TTTCACATAC
CAAGATTTTG ATATGGGAAC TCTTGGATTA GCTTATGTTG GCTCTCCCAG AGCAAACAGC
CATGGAGGTG TTTGTCCAAA GGCTTATTAT AGCCCAGTTG GGAAGAAAAA TATCTATTTG
AATAGTGGTT TGACGAGCAC AAAGAATTAT GGTAAAACCA TCCTTACAAA GGAAGCTGAC
CTGGTTACAA CTCATGAATT GGGACATAAT TTTGGAGCAG AACATGATCC GGATGGTCTA
GCAGAATGTG CCCCGAATGA GGACCAGGGA GGGAAATATG TCATGTATCC CATAGCTGTG
AGTGGCGATC ACGAGAACAA TAAGATGTTT TCAAACTGCA GTAAACAATC AATCTATAAG
ACCATTGAAA GTAAGGCCCA GGAGTGTTTT CAAGAACGCA GCAATAAAGT TTGTGGGAAC
TCGAGGGTGG ATGAAGGAGA AGAGTGTGAT CCTGGCATCA TGTATCTGAA CAACGACACC
TGCTGCAACA GCGACTGCAC GTTGAAGGAA GGTGTCCAGT GCAGTGACAG GAACAGTCCT
TGCTGTAAAA ACTGTCAGTT TGAGACTGCC CAGAAGAAGT GCCAGGAGGC GATTAATGCT
ACTTGCAAAG GCGTGTCCTA CTGCACAGGT AATAGCAGTG AGTGCCCGCC TCCAGGAAAT
GCTGAAGATG ACACTGTTTG CTTGGATCTT GGCAAGTGTA AGGATGGGAA ATGCATCCCT
TTCTGCGAGA GGGAACAGCA GCTGGAGTCC TGTGCATGTA ATGAAACTGA CAACTCCTGC
AAGGTGTGCT GCAGGGACCT TTCTGGCCGC TGTGTGCCCT ATGTCGATGC TGAACAAAAG
AACTTATTTT TGAGGAAAGG AAAGCCCTGT ACAGTAGGAT TTTGTGACAT GAATGGCAAA
TGTGAGAAAC GAGTACAGGA TGTAATTGAA CGATTTTGGG ATTTCATTGA CCAGCTGAGC
ATCAATACTT TTGGAAAGTT TTTAGCAGAC AACATCGTTG GGTCTGTCCT GGTTTTCTCC
TTGATATTTT GGATTCCTTT CAGCATTCTT GTCCATTGTG TGGATAAGAA ATTGGATAAA
CAGTATGAAT CTCTGTCTCT GTTTCACCCC AGTAACGTCG AAATGCTGAG CAGCATGGAT
TCTGCATCGG TTCGCATTAT CAAACCCTTT CCTGCGCCCC AGACTCCAGG CCGCCTGCAG
CCTGCCCCTG TGATCCCTTC GGCGCCAGCA GCTCCAAAAC TGGACCACCA GAGAATGGAC
ACCATCCAGG AAGACCCCAG CACAGACTCA CATATGGACG AGGATGGGTT TGAGAAGGAC
CCCTTCCCAA ATAGCAGCAC AGCTGCCAAG TCATTTGAGG ATCTCACGGA CCATCCGGTC
ACCAGAAGTG AAAAGGCTGC CTCCTTTAAA CTGCAGCGTC AGAATCGTGT TGACAGCAAA
GAAACAGAGT GCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60845
Clone ID Related Accession (Same CDS sequence) XM_011510377 , XM_011510378
Accession Version XM_011510377.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1578bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product disintegrin and metalloproteinase domain-containing protein 17 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005334.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCAAAAA GTTACCCAAA TGAAGAAAAG GATGCTTGGG ATGTGAAGAT GTTGCTAGAG 
CAATTTAGCT TTGATATAGC TGAGGAAGCA TCTAAAGTTT GCTTGGCACA CCTTTTCACA
TACCAAGATT TTGATATGGG AACTCTTGGA TTAGCTTATG TTGGCTCTCC CAGAGCAAAC
AGCCATGGAG GTGTTTGTCC AAAGGCTTAT TATAGCCCAG TTGGGAAGAA AAATATCTAT
TTGAATAGTG GTTTGACGAG CACAAAGAAT TATGGTAAAA CCATCCTTAC AAAGGAAGCT
GACCTGGTTA CAACTCATGA ATTGGGACAT AATTTTGGAG CAGAACATGA TCCGGATGGT
CTAGCAGAAT GTGCCCCGAA TGAGGACCAG GGAGGGAAAT ATGTCATGTA TCCCATAGCT
GTGAGTGGCG ATCACGAGAA CAATAAGATG TTTTCAAACT GCAGTAAACA ATCAATCTAT
AAGACCATTG AAAGTAAGGC CCAGGAGTGT TTTCAAGAAC GCAGCAATAA AGTTTGTGGG
AACTCGAGGG TGGATGAAGG AGAAGAGTGT GATCCTGGCA TCATGTATCT GAACAACGAC
ACCTGCTGCA ACAGCGACTG CACGTTGAAG GAAGGTGTCC AGTGCAGTGA CAGGAACAGT
CCTTGCTGTA AAAACTGTCA GTTTGAGACT GCCCAGAAGA AGTGCCAGGA GGCGATTAAT
GCTACTTGCA AAGGCGTGTC CTACTGCACA GGTAATAGCA GTGAGTGCCC GCCTCCAGGA
AATGCTGAAG ATGACACTGT TTGCTTGGAT CTTGGCAAGT GTAAGGATGG GAAATGCATC
CCTTTCTGCG AGAGGGAACA GCAGCTGGAG TCCTGTGCAT GTAATGAAAC TGACAACTCC
TGCAAGGTGT GCTGCAGGGA CCTTTCTGGC CGCTGTGTGC CCTATGTCGA TGCTGAACAA
AAGAACTTAT TTTTGAGGAA AGGAAAGCCC TGTACAGTAG GATTTTGTGA CATGAATGGC
AAATGTGAGA AACGAGTACA GGATGTAATT GAACGATTTT GGGATTTCAT TGACCAGCTG
AGCATCAATA CTTTTGGAAA GTTTTTAGCA GACAACATCG TTGGGTCTGT CCTGGTTTTC
TCCTTGATAT TTTGGATTCC TTTCAGCATT CTTGTCCATT GTGTGGATAA GAAATTGGAT
AAACAGTATG AATCTCTGTC TCTGTTTCAC CCCAGTAACG TCGAAATGCT GAGCAGCATG
GATTCTGCAT CGGTTCGCAT TATCAAACCC TTTCCTGCGC CCCAGACTCC AGGCCGCCTG
CAGCCTGCCC CTGTGATCCC TTCGGCGCCA GCAGCTCCAA AACTGGACCA CCAGAGAATG
GACACCATCC AGGAAGACCC CAGCACAGAC TCACATATGG ACGAGGATGG GTTTGAGAAG
GACCCCTTCC CAAATAGCAG CACAGCTGCC AAGTCATTTG AGGATCTCAC GGACCATCCG
GTCACCAGAA GTGAAAAGGC TGCCTCCTTT AAACTGCAGC GTCAGAATCG TGTTGACAGC
AAAGAAACAG AGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011508679.1
CDS264..1841
Misc Feature(1)270..797(+)
Misc Feature(2)579..611(+)
Misc Feature(3)816..1046(+)
Misc Feature(4)1104..1292(+)
Misc Feature(5)1164..1271(+)
Misc Feature(6)1164..1175(+)
Translation

Target ORF information:

RefSeq Version XM_011510377
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011510377

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCAAAAA GTTACCCAAA TGAAGAAAAG GATGCTTGGG ATGTGAAGAT GTTGCTAGAG 
CAATTTAGCT TTGATATAGC TGAGGAAGCA TCTAAAGTTT GCTTGGCACA CCTTTTCACA
TACCAAGATT TTGATATGGG AACTCTTGGA TTAGCTTATG TTGGCTCTCC CAGAGCAAAC
AGCCATGGAG GTGTTTGTCC AAAGGCTTAT TATAGCCCAG TTGGGAAGAA AAATATCTAT
TTGAATAGTG GTTTGACGAG CACAAAGAAT TATGGTAAAA CCATCCTTAC AAAGGAAGCT
GACCTGGTTA CAACTCATGA ATTGGGACAT AATTTTGGAG CAGAACATGA TCCGGATGGT
CTAGCAGAAT GTGCCCCGAA TGAGGACCAG GGAGGGAAAT ATGTCATGTA TCCCATAGCT
GTGAGTGGCG ATCACGAGAA CAATAAGATG TTTTCAAACT GCAGTAAACA ATCAATCTAT
AAGACCATTG AAAGTAAGGC CCAGGAGTGT TTTCAAGAAC GCAGCAATAA AGTTTGTGGG
AACTCGAGGG TGGATGAAGG AGAAGAGTGT GATCCTGGCA TCATGTATCT GAACAACGAC
ACCTGCTGCA ACAGCGACTG CACGTTGAAG GAAGGTGTCC AGTGCAGTGA CAGGAACAGT
CCTTGCTGTA AAAACTGTCA GTTTGAGACT GCCCAGAAGA AGTGCCAGGA GGCGATTAAT
GCTACTTGCA AAGGCGTGTC CTACTGCACA GGTAATAGCA GTGAGTGCCC GCCTCCAGGA
AATGCTGAAG ATGACACTGT TTGCTTGGAT CTTGGCAAGT GTAAGGATGG GAAATGCATC
CCTTTCTGCG AGAGGGAACA GCAGCTGGAG TCCTGTGCAT GTAATGAAAC TGACAACTCC
TGCAAGGTGT GCTGCAGGGA CCTTTCTGGC CGCTGTGTGC CCTATGTCGA TGCTGAACAA
AAGAACTTAT TTTTGAGGAA AGGAAAGCCC TGTACAGTAG GATTTTGTGA CATGAATGGC
AAATGTGAGA AACGAGTACA GGATGTAATT GAACGATTTT GGGATTTCAT TGACCAGCTG
AGCATCAATA CTTTTGGAAA GTTTTTAGCA GACAACATCG TTGGGTCTGT CCTGGTTTTC
TCCTTGATAT TTTGGATTCC TTTCAGCATT CTTGTCCATT GTGTGGATAA GAAATTGGAT
AAACAGTATG AATCTCTGTC TCTGTTTCAC CCCAGTAACG TCGAAATGCT GAGCAGCATG
GATTCTGCAT CGGTTCGCAT TATCAAACCC TTTCCTGCGC CCCAGACTCC AGGCCGCCTG
CAGCCTGCCC CTGTGATCCC TTCGGCGCCA GCAGCTCCAA AACTGGACCA CCAGAGAATG
GACACCATCC AGGAAGACCC CAGCACAGAC TCACATATGG ACGAGGATGG GTTTGAGAAG
GACCCCTTCC CAAATAGCAG CACAGCTGCC AAGTCATTTG AGGATCTCAC GGACCATCCG
GTCACCAGAA GTGAAAAGGC TGCCTCCTTT AAACTGCAGC GTCAGAATCG TGTTGACAGC
AAAGAAACAG AGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60845
Clone ID Related Accession (Same CDS sequence) XM_011510377 , XM_011510378
Accession Version XM_011510378.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1578bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product disintegrin and metalloproteinase domain-containing protein 17 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005334.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCAAAAA GTTACCCAAA TGAAGAAAAG GATGCTTGGG ATGTGAAGAT GTTGCTAGAG 
CAATTTAGCT TTGATATAGC TGAGGAAGCA TCTAAAGTTT GCTTGGCACA CCTTTTCACA
TACCAAGATT TTGATATGGG AACTCTTGGA TTAGCTTATG TTGGCTCTCC CAGAGCAAAC
AGCCATGGAG GTGTTTGTCC AAAGGCTTAT TATAGCCCAG TTGGGAAGAA AAATATCTAT
TTGAATAGTG GTTTGACGAG CACAAAGAAT TATGGTAAAA CCATCCTTAC AAAGGAAGCT
GACCTGGTTA CAACTCATGA ATTGGGACAT AATTTTGGAG CAGAACATGA TCCGGATGGT
CTAGCAGAAT GTGCCCCGAA TGAGGACCAG GGAGGGAAAT ATGTCATGTA TCCCATAGCT
GTGAGTGGCG ATCACGAGAA CAATAAGATG TTTTCAAACT GCAGTAAACA ATCAATCTAT
AAGACCATTG AAAGTAAGGC CCAGGAGTGT TTTCAAGAAC GCAGCAATAA AGTTTGTGGG
AACTCGAGGG TGGATGAAGG AGAAGAGTGT GATCCTGGCA TCATGTATCT GAACAACGAC
ACCTGCTGCA ACAGCGACTG CACGTTGAAG GAAGGTGTCC AGTGCAGTGA CAGGAACAGT
CCTTGCTGTA AAAACTGTCA GTTTGAGACT GCCCAGAAGA AGTGCCAGGA GGCGATTAAT
GCTACTTGCA AAGGCGTGTC CTACTGCACA GGTAATAGCA GTGAGTGCCC GCCTCCAGGA
AATGCTGAAG ATGACACTGT TTGCTTGGAT CTTGGCAAGT GTAAGGATGG GAAATGCATC
CCTTTCTGCG AGAGGGAACA GCAGCTGGAG TCCTGTGCAT GTAATGAAAC TGACAACTCC
TGCAAGGTGT GCTGCAGGGA CCTTTCTGGC CGCTGTGTGC CCTATGTCGA TGCTGAACAA
AAGAACTTAT TTTTGAGGAA AGGAAAGCCC TGTACAGTAG GATTTTGTGA CATGAATGGC
AAATGTGAGA AACGAGTACA GGATGTAATT GAACGATTTT GGGATTTCAT TGACCAGCTG
AGCATCAATA CTTTTGGAAA GTTTTTAGCA GACAACATCG TTGGGTCTGT CCTGGTTTTC
TCCTTGATAT TTTGGATTCC TTTCAGCATT CTTGTCCATT GTGTGGATAA GAAATTGGAT
AAACAGTATG AATCTCTGTC TCTGTTTCAC CCCAGTAACG TCGAAATGCT GAGCAGCATG
GATTCTGCAT CGGTTCGCAT TATCAAACCC TTTCCTGCGC CCCAGACTCC AGGCCGCCTG
CAGCCTGCCC CTGTGATCCC TTCGGCGCCA GCAGCTCCAA AACTGGACCA CCAGAGAATG
GACACCATCC AGGAAGACCC CAGCACAGAC TCACATATGG ACGAGGATGG GTTTGAGAAG
GACCCCTTCC CAAATAGCAG CACAGCTGCC AAGTCATTTG AGGATCTCAC GGACCATCCG
GTCACCAGAA GTGAAAAGGC TGCCTCCTTT AAACTGCAGC GTCAGAATCG TGTTGACAGC
AAAGAAACAG AGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011508680.1
CDS270..1847
Misc Feature(1)276..803(+)
Misc Feature(2)585..617(+)
Misc Feature(3)822..1052(+)
Misc Feature(4)1110..1298(+)
Misc Feature(5)1170..1277(+)
Misc Feature(6)1170..1181(+)
Translation

Target ORF information:

RefSeq Version XM_011510378
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011510378

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCAAAAA GTTACCCAAA TGAAGAAAAG GATGCTTGGG ATGTGAAGAT GTTGCTAGAG 
CAATTTAGCT TTGATATAGC TGAGGAAGCA TCTAAAGTTT GCTTGGCACA CCTTTTCACA
TACCAAGATT TTGATATGGG AACTCTTGGA TTAGCTTATG TTGGCTCTCC CAGAGCAAAC
AGCCATGGAG GTGTTTGTCC AAAGGCTTAT TATAGCCCAG TTGGGAAGAA AAATATCTAT
TTGAATAGTG GTTTGACGAG CACAAAGAAT TATGGTAAAA CCATCCTTAC AAAGGAAGCT
GACCTGGTTA CAACTCATGA ATTGGGACAT AATTTTGGAG CAGAACATGA TCCGGATGGT
CTAGCAGAAT GTGCCCCGAA TGAGGACCAG GGAGGGAAAT ATGTCATGTA TCCCATAGCT
GTGAGTGGCG ATCACGAGAA CAATAAGATG TTTTCAAACT GCAGTAAACA ATCAATCTAT
AAGACCATTG AAAGTAAGGC CCAGGAGTGT TTTCAAGAAC GCAGCAATAA AGTTTGTGGG
AACTCGAGGG TGGATGAAGG AGAAGAGTGT GATCCTGGCA TCATGTATCT GAACAACGAC
ACCTGCTGCA ACAGCGACTG CACGTTGAAG GAAGGTGTCC AGTGCAGTGA CAGGAACAGT
CCTTGCTGTA AAAACTGTCA GTTTGAGACT GCCCAGAAGA AGTGCCAGGA GGCGATTAAT
GCTACTTGCA AAGGCGTGTC CTACTGCACA GGTAATAGCA GTGAGTGCCC GCCTCCAGGA
AATGCTGAAG ATGACACTGT TTGCTTGGAT CTTGGCAAGT GTAAGGATGG GAAATGCATC
CCTTTCTGCG AGAGGGAACA GCAGCTGGAG TCCTGTGCAT GTAATGAAAC TGACAACTCC
TGCAAGGTGT GCTGCAGGGA CCTTTCTGGC CGCTGTGTGC CCTATGTCGA TGCTGAACAA
AAGAACTTAT TTTTGAGGAA AGGAAAGCCC TGTACAGTAG GATTTTGTGA CATGAATGGC
AAATGTGAGA AACGAGTACA GGATGTAATT GAACGATTTT GGGATTTCAT TGACCAGCTG
AGCATCAATA CTTTTGGAAA GTTTTTAGCA GACAACATCG TTGGGTCTGT CCTGGTTTTC
TCCTTGATAT TTTGGATTCC TTTCAGCATT CTTGTCCATT GTGTGGATAA GAAATTGGAT
AAACAGTATG AATCTCTGTC TCTGTTTCAC CCCAGTAACG TCGAAATGCT GAGCAGCATG
GATTCTGCAT CGGTTCGCAT TATCAAACCC TTTCCTGCGC CCCAGACTCC AGGCCGCCTG
CAGCCTGCCC CTGTGATCCC TTCGGCGCCA GCAGCTCCAA AACTGGACCA CCAGAGAATG
GACACCATCC AGGAAGACCC CAGCACAGAC TCACATATGG ACGAGGATGG GTTTGAGAAG
GACCCCTTCC CAAATAGCAG CACAGCTGCC AAGTCATTTG AGGATCTCAC GGACCATCCG
GTCACCAGAA GTGAAAAGGC TGCCTCCTTT AAACTGCAGC GTCAGAATCG TGTTGACAGC
AAAGAAACAG AGTGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21940
Clone ID Related Accession (Same CDS sequence) NM_003183
Accession Version NM_003183.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2475bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disintegrin and metalloproteinase domain-containing protein 17 preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN258241.1, U86755.1, BX339672.2, U92649.1, U69611.1, BM725368.1 and BQ186514.1. This sequence is a reference standard in the RefSeqGene project. On Aug 24, 2005 this sequence version replaced gi:11497003. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ402545.1, U92649.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGAGGCAGT CTCTCCTATT CCTGACCAGC GTGGTTCCTT TCGTGCTGGC GCCGCGACCT 
CCGGATGACC CGGGCTTCGG CCCCCACCAG AGACTCGAGA AGCTTGATTC TTTGCTCTCA
GACTACGATA TTCTCTCTTT ATCTAATATC CAGCAGCATT CGGTAAGAAA AAGAGATCTA
CAGACTTCAA CACATGTAGA AACACTACTA ACTTTTTCAG CTTTGAAAAG GCATTTTAAA
TTATACCTGA CATCAAGTAC TGAACGTTTT TCACAAAATT TCAAGGTCGT GGTGGTGGAT
GGTAAAAACG AAAGCGAGTA CACTGTAAAA TGGCAGGACT TCTTCACTGG ACACGTGGTT
GGTGAGCCTG ACTCTAGGGT TCTAGCCCAC ATAAGAGATG ATGATGTTAT AATCAGAATC
AACACAGATG GGGCCGAATA TAACATAGAG CCACTTTGGA GATTTGTTAA TGATACCAAA
GACAAAAGAA TGTTAGTTTA TAAATCTGAA GATATCAAGA ATGTTTCACG TTTGCAGTCT
CCAAAAGTGT GTGGTTATTT AAAAGTGGAT AATGAAGAGT TGCTCCCAAA AGGGTTAGTA
GACAGAGAAC CACCTGAAGA GCTTGTTCAT CGAGTGAAAA GAAGAGCTGA CCCAGATCCC
ATGAAGAACA CGTGTAAATT ATTGGTGGTA GCAGATCATC GCTTCTACAG ATACATGGGC
AGAGGGGAAG AGAGTACAAC TACAAATTAC TTAATAGAGC TAATTGACAG AGTTGATGAC
ATCTATCGGA ACACTTCATG GGATAATGCA GGTTTTAAAG GCTATGGAAT ACAGATAGAG
CAGATTCGCA TTCTCAAGTC TCCACAAGAG GTAAAACCTG GTGAAAAGCA CTACAACATG
GCAAAAAGTT ACCCAAATGA AGAAAAGGAT GCTTGGGATG TGAAGATGTT GCTAGAGCAA
TTTAGCTTTG ATATAGCTGA GGAAGCATCT AAAGTTTGCT TGGCACACCT TTTCACATAC
CAAGATTTTG ATATGGGAAC TCTTGGATTA GCTTATGTTG GCTCTCCCAG AGCAAACAGC
CATGGAGGTG TTTGTCCAAA GGCTTATTAT AGCCCAGTTG GGAAGAAAAA TATCTATTTG
AATAGTGGTT TGACGAGCAC AAAGAATTAT GGTAAAACCA TCCTTACAAA GGAAGCTGAC
CTGGTTACAA CTCATGAATT GGGACATAAT TTTGGAGCAG AACATGATCC GGATGGTCTA
GCAGAATGTG CCCCGAATGA GGACCAGGGA GGGAAATATG TCATGTATCC CATAGCTGTG
AGTGGCGATC ACGAGAACAA TAAGATGTTT TCAAACTGCA GTAAACAATC AATCTATAAG
ACCATTGAAA GTAAGGCCCA GGAGTGTTTT CAAGAACGCA GCAATAAAGT TTGTGGGAAC
TCGAGGGTGG ATGAAGGAGA AGAGTGTGAT CCTGGCATCA TGTATCTGAA CAACGACACC
TGCTGCAACA GCGACTGCAC GTTGAAGGAA GGTGTCCAGT GCAGTGACAG GAACAGTCCT
TGCTGTAAAA ACTGTCAGTT TGAGACTGCC CAGAAGAAGT GCCAGGAGGC GATTAATGCT
ACTTGCAAAG GCGTGTCCTA CTGCACAGGT AATAGCAGTG AGTGCCCGCC TCCAGGAAAT
GCTGAAGATG ACACTGTTTG CTTGGATCTT GGCAAGTGTA AGGATGGGAA ATGCATCCCT
TTCTGCGAGA GGGAACAGCA GCTGGAGTCC TGTGCATGTA ATGAAACTGA CAACTCCTGC
AAGGTGTGCT GCAGGGACCT TTCTGGCCGC TGTGTGCCCT ATGTCGATGC TGAACAAAAG
AACTTATTTT TGAGGAAAGG AAAGCCCTGT ACAGTAGGAT TTTGTGACAT GAATGGCAAA
TGTGAGAAAC GAGTACAGGA TGTAATTGAA CGATTTTGGG ATTTCATTGA CCAGCTGAGC
ATCAATACTT TTGGAAAGTT TTTAGCAGAC AACATCGTTG GGTCTGTCCT GGTTTTCTCC
TTGATATTTT GGATTCCTTT CAGCATTCTT GTCCATTGTG TGGATAAGAA ATTGGATAAA
CAGTATGAAT CTCTGTCTCT GTTTCACCCC AGTAACGTCG AAATGCTGAG CAGCATGGAT
TCTGCATCGG TTCGCATTAT CAAACCCTTT CCTGCGCCCC AGACTCCAGG CCGCCTGCAG
CCTGCCCCTG TGATCCCTTC GGCGCCAGCA GCTCCAAAAC TGGACCACCA GAGAATGGAC
ACCATCCAGG AAGACCCCAG CACAGACTCA CATATGGACG AGGATGGGTT TGAGAAGGAC
CCCTTCCCAA ATAGCAGCAC AGCTGCCAAG TCATTTGAGG ATCTCACGGA CCATCCGGTC
ACCAGAAGTG AAAAGGCTGC CTCCTTTAAA CTGCAGCGTC AGAATCGTGT TGACAGCAAA
GAAACAGAGT GCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003174.3
CDS184..2658
Misc Feature(1)82..84(+)
Misc Feature(2)307..684(+)
Misc Feature(3)727..750(+)
Misc Feature(4)850..1614(+)
Misc Feature(5)1318..1320(+)
Misc Feature(6)1327..1329(+)
Misc Feature(7)1396..1428(+)
Misc Feature(8)1633..1863(+)
Misc Feature(9)1894..1989(+)
Misc Feature(10)1921..2109(+)
Misc Feature(11)1981..2088(+)
Misc Feature(12)1981..1992(+)
Misc Feature(13)1990..2196(+)
Misc Feature(14)2197..2265(+)
Misc Feature(15)2197..2259(+)
Misc Feature(16)2266..2655(+)
Misc Feature(17)2386..2388(+)
Misc Feature(18)2554..2556(+)
Misc Feature(19)2554..2556(+)
Misc Feature(20)2554..2556(+)
Misc Feature(21)2638..2640(+)
Misc Feature(22)2638..2640(+)
Exon (1)1..280
Gene:ADAM17
Gene Synonym:
Exon (2)281..413
Gene:ADAM17
Gene Synonym:
Exon (3)414..544
Gene:ADAM17
Gene Synonym:
Exon (4)545..633
Gene:ADAM17
Gene Synonym:
Exon (5)634..802
Gene:ADAM17
Gene Synonym:
Exon (6)803..936
Gene:ADAM17
Gene Synonym:
Exon (7)937..1026
Gene:ADAM17
Gene Synonym:
Exon (8)1027..1140
Gene:ADAM17
Gene Synonym:
Exon (9)1141..1285
Gene:ADAM17
Gene Synonym:
Exon (10)1286..1374
Gene:ADAM17
Gene Synonym:
Exon (11)1375..1527
Gene:ADAM17
Gene Synonym:
Exon (12)1528..1727
Gene:ADAM17
Gene Synonym:
Exon (13)1728..1831
Gene:ADAM17
Gene Synonym:
Exon (14)1832..1966
Gene:ADAM17
Gene Synonym:
Exon (15)1967..2097
Gene:ADAM17
Gene Synonym:
Exon (16)2098..2176
Gene:ADAM17
Gene Synonym:
Exon (17)2177..2265
Gene:ADAM17
Gene Synonym:
Exon (18)2266..2316
Gene:ADAM17
Gene Synonym:
Exon (19)2317..3572
Gene:ADAM17
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_003183
Organism Homo sapiens (human)
Definition Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003183

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGAGGCAGT CTCTCCTATT CCTGACCAGC GTGGTTCCTT TCGTGCTGGC GCCGCGACCT 
CCGGATGACC CGGGCTTCGG CCCCCACCAG AGACTCGAGA AGCTTGATTC TTTGCTCTCA
GACTACGATA TTCTCTCTTT ATCTAATATC CAGCAGCATT CGGTAAGAAA AAGAGATCTA
CAGACTTCAA CACATGTAGA AACACTACTA ACTTTTTCAG CTTTGAAAAG GCATTTTAAA
TTATACCTGA CATCAAGTAC TGAACGTTTT TCACAAAATT TCAAGGTCGT GGTGGTGGAT
GGTAAAAACG AAAGCGAGTA CACTGTAAAA TGGCAGGACT TCTTCACTGG ACACGTGGTT
GGTGAGCCTG ACTCTAGGGT TCTAGCCCAC ATAAGAGATG ATGATGTTAT AATCAGAATC
AACACAGATG GGGCCGAATA TAACATAGAG CCACTTTGGA GATTTGTTAA TGATACCAAA
GACAAAAGAA TGTTAGTTTA TAAATCTGAA GATATCAAGA ATGTTTCACG TTTGCAGTCT
CCAAAAGTGT GTGGTTATTT AAAAGTGGAT AATGAAGAGT TGCTCCCAAA AGGGTTAGTA
GACAGAGAAC CACCTGAAGA GCTTGTTCAT CGAGTGAAAA GAAGAGCTGA CCCAGATCCC
ATGAAGAACA CGTGTAAATT ATTGGTGGTA GCAGATCATC GCTTCTACAG ATACATGGGC
AGAGGGGAAG AGAGTACAAC TACAAATTAC TTAATAGAGC TAATTGACAG AGTTGATGAC
ATCTATCGGA ACACTTCATG GGATAATGCA GGTTTTAAAG GCTATGGAAT ACAGATAGAG
CAGATTCGCA TTCTCAAGTC TCCACAAGAG GTAAAACCTG GTGAAAAGCA CTACAACATG
GCAAAAAGTT ACCCAAATGA AGAAAAGGAT GCTTGGGATG TGAAGATGTT GCTAGAGCAA
TTTAGCTTTG ATATAGCTGA GGAAGCATCT AAAGTTTGCT TGGCACACCT TTTCACATAC
CAAGATTTTG ATATGGGAAC TCTTGGATTA GCTTATGTTG GCTCTCCCAG AGCAAACAGC
CATGGAGGTG TTTGTCCAAA GGCTTATTAT AGCCCAGTTG GGAAGAAAAA TATCTATTTG
AATAGTGGTT TGACGAGCAC AAAGAATTAT GGTAAAACCA TCCTTACAAA GGAAGCTGAC
CTGGTTACAA CTCATGAATT GGGACATAAT TTTGGAGCAG AACATGATCC GGATGGTCTA
GCAGAATGTG CCCCGAATGA GGACCAGGGA GGGAAATATG TCATGTATCC CATAGCTGTG
AGTGGCGATC ACGAGAACAA TAAGATGTTT TCAAACTGCA GTAAACAATC AATCTATAAG
ACCATTGAAA GTAAGGCCCA GGAGTGTTTT CAAGAACGCA GCAATAAAGT TTGTGGGAAC
TCGAGGGTGG ATGAAGGAGA AGAGTGTGAT CCTGGCATCA TGTATCTGAA CAACGACACC
TGCTGCAACA GCGACTGCAC GTTGAAGGAA GGTGTCCAGT GCAGTGACAG GAACAGTCCT
TGCTGTAAAA ACTGTCAGTT TGAGACTGCC CAGAAGAAGT GCCAGGAGGC GATTAATGCT
ACTTGCAAAG GCGTGTCCTA CTGCACAGGT AATAGCAGTG AGTGCCCGCC TCCAGGAAAT
GCTGAAGATG ACACTGTTTG CTTGGATCTT GGCAAGTGTA AGGATGGGAA ATGCATCCCT
TTCTGCGAGA GGGAACAGCA GCTGGAGTCC TGTGCATGTA ATGAAACTGA CAACTCCTGC
AAGGTGTGCT GCAGGGACCT TTCTGGCCGC TGTGTGCCCT ATGTCGATGC TGAACAAAAG
AACTTATTTT TGAGGAAAGG AAAGCCCTGT ACAGTAGGAT TTTGTGACAT GAATGGCAAA
TGTGAGAAAC GAGTACAGGA TGTAATTGAA CGATTTTGGG ATTTCATTGA CCAGCTGAGC
ATCAATACTT TTGGAAAGTT TTTAGCAGAC AACATCGTTG GGTCTGTCCT GGTTTTCTCC
TTGATATTTT GGATTCCTTT CAGCATTCTT GTCCATTGTG TGGATAAGAA ATTGGATAAA
CAGTATGAAT CTCTGTCTCT GTTTCACCCC AGTAACGTCG AAATGCTGAG CAGCATGGAT
TCTGCATCGG TTCGCATTAT CAAACCCTTT CCTGCGCCCC AGACTCCAGG CCGCCTGCAG
CCTGCCCCTG TGATCCCTTC GGCGCCAGCA GCTCCAAAAC TGGACCACCA GAGAATGGAC
ACCATCCAGG AAGACCCCAG CACAGACTCA CATATGGACG AGGATGGGTT TGAGAAGGAC
CCCTTCCCAA ATAGCAGCAC AGCTGCCAAG TCATTTGAGG ATCTCACGGA CCATCCGGTC
ACCAGAAGTG AAAAGGCTGC CTCCTTTAAA CTGCAGCGTC AGAATCGTGT TGACAGCAAA
GAAACAGAGT GCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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