SHOC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SHOC2
Entrez Gene ID	8036
Full Name	SHOC2, leucine rich repeat scaffold protein
Synonyms	SIAA0862,SOC2,SUR8
General protein information	Preferred Names SHOC2, leucine rich repeat scaffold protein Names leucine-rich repeat protein SHOC-2 soc-2 suppressor of clear homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q25.2
Summary	This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair. [provided by RefSeq, May 2010].
Disorder MIM:	602775
Disorder Html:	Noonan-like syndrome with loose anagen hair, 607721 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017016704.1	XP_016872193.1	leucine-rich repeat protein SHOC-2 isoform X1
NM_007373.3	NP_031399.2	leucine-rich repeat protein SHOC-2 isoform 1
XM_017016702.1	XP_016872191.1	leucine-rich repeat protein SHOC-2 isoform X1
XM_017016703.1	XP_016872192.1	leucine-rich repeat protein SHOC-2 isoform X1
NM_001324336.1	NP_001311265.1	leucine-rich repeat protein SHOC-2 isoform 1
NM_001269039.2	NP_001255968.1	leucine-rich repeat protein SHOC-2 isoform 2
NM_007373.4	NP_031399.2	leucine-rich repeat protein SHOC-2 isoform 1
NM_001324337.1	NP_001311266.1	leucine-rich repeat protein SHOC-2 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SHOC2	NP_031399.2
Pan troglodytes (chimpanzee)	SHOC2	XP_521602.2
Mus musculus (house mouse)	Shoc2	NP_062632.2
Gallus gallus (chicken)	SHOC2	NP_001026407.1
Danio rerio (zebrafish)	shoc2	NP_001038251.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004485	XP_313783.5
Oryza sativa (rice)	Os10g0119200	NP_001064062.2
Canis lupus familiaris (dog)	SHOC2	XP_535013.2
Bos taurus (cattle)	SHOC2	NP_001095413.1
Drosophila melanogaster (fruit fly)	Sur-8	NP_001262665.1
	SHOC2	XP_001087610.1
Rattus norvegicus (Norway rat)	Shoc2	NP_001013173.1
Caenorhabditis elegans (roundworm)	soc-2	NP_741391.2
Xenopus tropicalis (tropical clawed frog)	shoc2	XP_004915781.1

Gene Ontology
Bibliography

Related articles in PubMed

SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling.
Motta M, Chillemi G, Fodale V, Cecchetti S, Coppola S, Stipo S, Cordeddu V, Macioce P, Gelb BD, Tartaglia M
Human molecular genetics25(17)3824-3835(2016 09)

Sur8 mediates tumorigenesis and metastasis in colorectal cancer.
Lee YM, Kaduwal S, Lee KH, Park JC, Jeong WJ, Choi KY
Experimental & molecular medicine48(7)e249(2016 Jul)

Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.
Jang ER, Jang H, Shi P, Popa G, Jeoung M, Galperin E
Journal of cell science128(23)4428-41(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results provide evidence that SHOC2 trapping at different subcellular sites has a diverse impact on ERK signaling strength and dynamics, suggesting a dual counteracting modulatory role of SHOC2 in the control of ERK signaling exerted at different intracellular compartments.
Title: SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling.

Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of colorectal cancer (CRC) cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells.
Title: Sur8 mediates tumorigenesis and metastasis in colorectal cancer.

results demonstrate that PSMC5 is a new and important player involved in regulating ERK1/2 signal transmission through the remodeling of Shoc2 scaffold complex in a spatially-defined manner.
Title: Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.

Two unrelated Taiwanese patients have been described with Noonan-like syndrome with loose anagen hair who also have moyamoya disease and in whom heterozygous germline mutation in SHOC2 was found.
Title: Moyamoya disease in two patients with Noonan-like syndrome with loose anagen hair.

ectopic overexpression of human Shoc2 in PC12 cells significantly promotes neurite extension in the presence of Epidermal Growth Factor, a stimulus that induces proliferation rather than differentiation in these cells.
Title: Shoc2/Sur8 protein regulates neurite outgrowth.

The following SHOC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SHOC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19647	NM_001324336.1 Latest version!	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu19647	NM_007373.4 Latest version!	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu19647	NM_001324337.1 Latest version!	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu19647	XM_017016702.1 Latest version!	Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu19647	XM_017016704.1 Latest version!	Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu19647	XM_017016703.1 Latest version!	Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu22681	NM_001269039.2 Latest version!	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu19647	NM_007373.3	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SHOC2 ( NM_007373.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_031399.2 Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 1, mRNA.

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CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	NM_007373.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-27
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB451165.1, BC050445.1 and BC044752.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced XM_005270186.1, NM_007373.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 3, and 4 all encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC044752.1, SRR1803614.176919.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031399.2
CDS	350..2098
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	NM_007373.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007373.3

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( NM_001324336.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311265.1 Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	NM_001324336.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158163.11. Transcript Variant: This variant (3), as well as variants 1 and 4, encodes isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.185791.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311265.1
CDS	307..2055
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	NM_001324336.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324336.1

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( NM_007373.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_031399.2 Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 1, mRNA.

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CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	NM_007373.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB451165.1, BC050445.1 and BC044752.1. On Dec 4, 2019 this sequence version replaced NM_007373.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 3, and 4 all encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.1912079.1, SRR1660805.134159.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031399.2
CDS	289..2037
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	NM_007373.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007373.4

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( NM_001324337.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311266.1 Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 4, mRNA.

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CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	NM_001324337.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158163.11. Transcript Variant: This variant (4), as well as variants 1 and 3, encodes isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660803.120322.1, SRR1660803.178475.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311266.1
CDS	535..2283
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	NM_001324337.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324337.1

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( XM_017016704.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872193.1 Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	XM_017016704.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872193.1
CDS	254..2002
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	XM_017016704.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016704.1

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( XM_017016702.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872191.1 Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X1, mRNA.

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CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	XM_017016702.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872191.1
CDS	255..2003
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	XM_017016702.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016702.1

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( XM_017016703.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872192.1 Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu19647
Clone ID Related Accession (Same CDS sequence)	XM_017016704.1 , NM_007373.3 , XM_017016702.1 , XM_017016703.1 , NM_001324336.1 , NM_007373.4 , NM_001324337.1
Accession Version	XM_017016703.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872192.1
CDS	6072..7820
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	XM_017016703.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine-rich repeat scaffold protein (SHOC2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016703.1

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGTGAATT ATGTAACCTC 
ATTACGCTGG ATGTAGCTCA CAATCAACTT GAACACCTTC CAAAGGAGAT TGGAAACTGT 
ACACAGATAA CCAACCTTGA CTTGCAGCAC AATGAACTGC TAGACCTCCC AGATACTATA 
GGAAACCTGT CCAGTTTAAG TCGTCTTGGT CTGAGATATA ACAGACTGTC AGCAATACCC 
AGATCATTAG CAAAATGCAG TGCACTTGAA GAATTAAATT TAGAGAACAA TAACATTTCT 
ACTTTACCAG AGAGTCTTTT ATCAAGTCTT GTGAAACTGA ATAGTTTGAC CTTAGCTAGA 
AATTGCTTCC AGTTGTATCC AGTGGGTGGT CCATCTCAGT TTTCTACCAT CTATTCCCTC 
AACATGGAAC ACAATCGAAT CAACAAAATT CCATTTGGAA TTTTCTCCAG AGCAAAAGTA 
TTAAGTAAGC TGAATATGAA GGACAATCAG TTAACATCAC TTCCCTTGGA TTTTGGAACT 
TGGACCAGTA TGGTAGAATT GAATTTAGCC ACTAATCAGC TCACAAAGAT CCCTGAGGAT 
GTGTCTGGTC TCGTTTCTCT TGAGGTTCTT ATCTTATCAA ACAATCTTCT AAAGAAGCTT 
CCCCATGGTC TTGGAAACCT TAGGAAGTTA AGAGAGTTGG ATCTAGAAGA GAACAAATTG 
GAATCCTTGC CAAATGAAAT TGCATATCTT AAGGATTTAC AGAAATTAGT CTTGACAAAC 
AACCAGTTGA CCACTCTTCC CAGAGGCATT GGTCACCTTA CTAATCTCAC ACATCTGGGC 
CTTGGAGAGA ACCTACTTAC TCACCTTCCT GAAGAAATTG GTACACTGGA GAACCTAGAA 
GAACTGTATT TGAATGACAA CCCCAACCTG CATAGCCTTC CCTTTGAGCT GGCACTCTGC 
AGCAAGCTTT CAATCATGAG TATTGAGAAC TGTCCACTCA GTCACCTTCC ACCTCAGATT 
GTTGCTGGGG GGCCTTCTTT CATCATTCAG TTCTTAAAGA TGCAGGGTCC ATATCGTGCC 
ATGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHOC2 ( NM_001269039.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001255968.1 Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22681
Clone ID Related Accession (Same CDS sequence)	NM_001269039.2
Accession Version	NM_001269039.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Homo sapiens(human)
Product	leucine-rich repeat protein SHOC-2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158163.11. On Apr 29, 2016 this sequence version replaced NM_001269039.1. Transcript Variant: This variant (2) lacks an in-frame splice site in the coding region, compared to variant 1. It encodes isoform 2 which is shorter, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660807.48904.1, SRR1803614.77450.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGAAACCT GTCCAGTTTA 
AGTCGTCTTG GTCTGAGATA TAACAGACTG TCAGCAATAC CCAGATCATT AGCAAAATGC 
AGTGCACTTG AAGAATTAAA TTTAGAGAAC AATAACATTT CTACTTTACC AGAGAGTCTT 
TTATCAAGTC TTGTGAAACT GAATAGTTTG ACCTTAGCTA GAAATTGCTT CCAGTTGTAT 
CCAGTGGGTG GTCCATCTCA GTTTTCTACC ATCTATTCCC TCAACATGGA ACACAATCGA 
ATCAACAAAA TTCCATTTGG AATTTTCTCC AGAGCAAAAG TATTAAGTAA GCTGAATATG 
AAGGACAATC AGTTAACATC ACTTCCCTTG GATTTTGGAA CTTGGACCAG TATGGTAGAA 
TTGAATTTAG CCACTAATCA GCTCACAAAG ATCCCTGAGG ATGTGTCTGG TCTCGTTTCT 
CTTGAGGTTC TTATCTTATC AAACAATCTT CTAAAGAAGC TTCCCCATGG TCTTGGAAAC 
CTTAGGAAGT TAAGAGAGTT GGATCTAGAA GAGAACAAAT TGGAATCCTT GCCAAATGAA 
ATTGCATATC TTAAGGATTT ACAGAAATTA GTCTTGACAA ACAACCAGTT GACCACTCTT 
CCCAGAGGCA TTGGTCACCT TACTAATCTC ACACATCTGG GCCTTGGAGA GAACCTACTT 
ACTCACCTTC CTGAAGAAAT TGGTACACTG GAGAACCTAG AAGAACTGTA TTTGAATGAC 
AACCCCAACC TGCATAGCCT TCCCTTTGAG CTGGCACTCT GCAGCAAGCT TTCAATCATG 
AGTATTGAGA ACTGTCCACT CAGTCACCTT CCACCTCAGA TTGTTGCTGG GGGGCCTTCT 
TTCATCATTC AGTTCTTAAA GATGCAGGGT CCATATCGTG CCATGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001255968.1
CDS	350..1960
Translation	MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV

Target ORF information:

RefSeq Version	NM_001269039.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHOC2 leucine rich repeat scaffold protein (SHOC2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001269039.2

ORF Insert Sequence:

ATGAGTAGTA GTTTAGGAAA AGAAAAAGAC TCTAAAGAAA AAGATCCCAA AGTACCATCA 
GCCAAGGAAA GAGAAAAGGA GGCAAAAGCC TCTGGAGGTT TTGGGAAAGA GAGCAAAGAA 
AAAGAACCTA AGACCAAAGG GAAAGATGCC AAAGATGGAA AGAAGGACTC CAGTGCTGCC 
CAACCAGGGG TGGCATTTTC AGTTGACAAT ACGATCAAAC GGCCAAACCC AGCACCTGGG 
ACTAGAAAAA AATCCAGCAA TGCAGAGGTG ATTAAAGAGC TCAACAAATG CCGGGAAGAG 
AATTCAATGC GTTTGGACTT ATCCAAGAGA TCTATACACA TATTGCCATC ATCAATCAAA 
GAGTTGACTC AATTAACAGA ACTTTATTTA TACAGTAACA AATTGCAGTC CCTCCCAGCA 
GAGGTGGGAT GTTTAGTAAA TCTCATGACA CTGGCTCTAA GTGAAAATTC ACTTACCAGT 
TTGCCTGACT CTCTTGATAA CTTGAAGAAG CTGCGGATGC TTGATTTACG GCATAATAAA 
CTGAGAGAAA TTCCTTCAGT GGTGTATAGG CTGGATTCTC TCACCACTCT TTACCTTCGC 
TTTAATCGTA TAACTACTGT GGAAAAGGAC ATCAAAAACT TGTCAAAACT CAGCATGCTT 
AGCATTCGAG AGAACAAAAT TAAACAACTA CCTGCTGAAA TTGGAAACCT GTCCAGTTTA 
AGTCGTCTTG GTCTGAGATA TAACAGACTG TCAGCAATAC CCAGATCATT AGCAAAATGC 
AGTGCACTTG AAGAATTAAA TTTAGAGAAC AATAACATTT CTACTTTACC AGAGAGTCTT 
TTATCAAGTC TTGTGAAACT GAATAGTTTG ACCTTAGCTA GAAATTGCTT CCAGTTGTAT 
CCAGTGGGTG GTCCATCTCA GTTTTCTACC ATCTATTCCC TCAACATGGA ACACAATCGA 
ATCAACAAAA TTCCATTTGG AATTTTCTCC AGAGCAAAAG TATTAAGTAA GCTGAATATG 
AAGGACAATC AGTTAACATC ACTTCCCTTG GATTTTGGAA CTTGGACCAG TATGGTAGAA 
TTGAATTTAG CCACTAATCA GCTCACAAAG ATCCCTGAGG ATGTGTCTGG TCTCGTTTCT 
CTTGAGGTTC TTATCTTATC AAACAATCTT CTAAAGAAGC TTCCCCATGG TCTTGGAAAC 
CTTAGGAAGT TAAGAGAGTT GGATCTAGAA GAGAACAAAT TGGAATCCTT GCCAAATGAA 
ATTGCATATC TTAAGGATTT ACAGAAATTA GTCTTGACAA ACAACCAGTT GACCACTCTT 
CCCAGAGGCA TTGGTCACCT TACTAATCTC ACACATCTGG GCCTTGGAGA GAACCTACTT 
ACTCACCTTC CTGAAGAAAT TGGTACACTG GAGAACCTAG AAGAACTGTA TTTGAATGAC 
AACCCCAACC TGCATAGCCT TCCCTTTGAG CTGGCACTCT GCAGCAAGCT TTCAATCATG 
AGTATTGAGA ACTGTCCACT CAGTCACCTT CCACCTCAGA TTGTTGCTGG GGGGCCTTCT 
TTCATCATTC AGTTCTTAAA GATGCAGGGT CCATATCGTG CCATGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling.
Human molecular genetics25(17)3824-3835(2016 09)
Motta M,Chillemi G,Fodale V,Cecchetti S,Coppola S,Stipo S,Cordeddu V,Macioce P,Gelb BD,Tartaglia M

Sur8 mediates tumorigenesis and metastasis in colorectal cancer.
Experimental & molecular medicine48(7)e249(2016 Jul)
Lee YM,Kaduwal S,Lee KH,Park JC,Jeong WJ,Choi KY

Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.
Journal of cell science128(23)4428-41(2015 Dec)
Jang ER,Jang H,Shi P,Popa G,Jeoung M,Galperin E

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SHOC2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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