Gene Symbol | Edem2 |
Entrez Gene ID | 108687 |
Full Name | ER degradation enhancer, mannosidase alpha-like 2 |
Synonyms | 9530090G24Rik,AI327354 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Edem2 cDNA ORF clone
gRNAs
Gene Symbol | Edem2 |
Entrez Gene ID | 108687 |
Full Name | ER degradation enhancer, mannosidase alpha-like 2 |
Synonyms | 9530090G24Rik,AI327354 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006498555.1 | XP_006498618.1 | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 |
NM_145537.2 | NP_663512.2 | ER degradation-enhancing alpha-mannosidase-like protein 2 precursor |
XM_030246529.1 | XP_030102389.1 | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 |
Homo sapiens (human) | EDEM2 | NP_060687.2 |
EDEM2 | XP_001101476.1 | |
Danio rerio (zebrafish) | edem2 | XP_005174174.1 |
Bos taurus (cattle) | EDEM2 | NP_001094555.1 |
Mus musculus (house mouse) | Edem2 | NP_663512.2 |
Drosophila melanogaster (fruit fly) | Edem1 | NP_001245483.1 |
Xenopus tropicalis (tropical clawed frog) | edem2 | NP_001005031.1 |
Pan troglodytes (chimpanzee) | EDEM2 | XP_514601.1 |
Canis lupus familiaris (dog) | EDEM2 | XP_534400.1 |
Rattus norvegicus (Norway rat) | Edem2 | NP_001004230.1 |
Oryza sativa (rice) | Os01g0773600 | NP_001044401.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012463 | XP_001231048.2 |
Caenorhabditis elegans (roundworm) | F10C2.5 | NP_506018.1 |
Arabidopsis thaliana (thale cress) | AT5G43710 | NP_199184.1 |
Gallus gallus (chicken) | EDEM2 | XP_003642546.1 |
The role of EDEM2 compared with EDEM1?in ricin transport from the endoplasmic reticulum to the cytosol.
S?omi?ska-Wojew?dzka M, Pawlik A, Soko?owska I, Antoniewicz J, W?grzyn G, Sandvig K
The Biochemical journal457(3)485-96(2014 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest Edem1/Edem2 participate in ricin translocation; overexpression of Edem2, in contrast to Edem1, directly promotes ricin subunit A transport from endoplasmic reticulum (ER) to cytosol; this translocation is not dependent on ER translocon.
Title: The role of EDEM2 compared with EDEM1?in ricin transport from the endoplasmic reticulum to the cytosol.
The following Edem2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Edem2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15650 | |
Clone ID Related Accession (Same CDS sequence) | NM_145537.2 | |
Accession Version | NM_145537.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1734bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-21 | |
Organism | Mus musculus(house mouse) | |
Product | ER degradation-enhancing alpha-mannosidase-like protein 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY289191.1, AK166998.1 and AL929233.9. On Jul 21, 2009 this sequence version replaced NM_145537.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK029164.1, AK079296.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTTTCC GGCTACTCAT CCCGCTCGGC CTCGTGTGCG TGCTGCTACC CCTGCACCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663512.2 |
CDS | 139..1872 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCCTTTCC GGCTACTCAT CCCGCTCGGC CTCGTGTGCG TGCTGCTACC CCTGCACCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29905 | |
Clone ID Related Accession (Same CDS sequence) | XM_006498555.1 , XM_030246529.1 | |
Accession Version | XM_006498555.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATGT TCCTAGAGTA CAACAAAGCC ATCCGGAATT ACACGCACTT CGATGACTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006498618.1 |
CDS | 510..1415 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCATGT TCCTAGAGTA CAACAAAGCC ATCCGGAATT ACACGCACTT CGATGACTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29905 | |
Clone ID Related Accession (Same CDS sequence) | XM_006498555.1 , XM_030246529.1 | |
Accession Version | XM_030246529.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATGT TCCTAGAGTA CAACAAAGCC ATCCGGAATT ACACGCACTT CGATGACTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030102389.1 |
CDS | 742..1647 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCATGT TCCTAGAGTA CAACAAAGCC ATCCGGAATT ACACGCACTT CGATGACTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The role of EDEM2 compared with EDEM1?in ricin transport from the endoplasmic reticulum to the cytosol. |