Gene Symbol | Edem2 |
Entrez Gene ID | 296304 |
Full Name | ER degradation enhancing alpha-mannosidase like protein 2 |
Synonyms | RGD1303074 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Edem2 cDNA ORF clone
gRNAs
Gene Symbol | Edem2 |
Entrez Gene ID | 296304 |
Full Name | ER degradation enhancing alpha-mannosidase like protein 2 |
Synonyms | RGD1303074 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001004230.1 | NP_001004230.1 | ER degradation-enhancing alpha-mannosidase-like protein 2 precursor |
Homo sapiens (human) | EDEM2 | NP_060687.2 |
EDEM2 | XP_001101476.1 | |
Danio rerio (zebrafish) | edem2 | XP_005174174.1 |
Bos taurus (cattle) | EDEM2 | NP_001094555.1 |
Mus musculus (house mouse) | Edem2 | NP_663512.2 |
Drosophila melanogaster (fruit fly) | Edem1 | NP_001245483.1 |
Xenopus tropicalis (tropical clawed frog) | edem2 | NP_001005031.1 |
Pan troglodytes (chimpanzee) | EDEM2 | XP_514601.1 |
Canis lupus familiaris (dog) | EDEM2 | XP_534400.1 |
Rattus norvegicus (Norway rat) | Edem2 | NP_001004230.1 |
Oryza sativa (rice) | Os01g0773600 | NP_001044401.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012463 | XP_001231048.2 |
Caenorhabditis elegans (roundworm) | F10C2.5 | NP_506018.1 |
Arabidopsis thaliana (thale cress) | AT5G43710 | NP_199184.1 |
Gallus gallus (chicken) | EDEM2 | XP_003642546.1 |
EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.
Ninagawa S, Okada T, Sumitomo Y, Kamiya Y, Kato K, Horimoto S, Ishikawa T, Takeda S, Sakuma T, Yamamoto T, Mori K
The Journal of cell biology206(3)347-56(2014 Aug)
The role of EDEM2 compared with EDEM1?in ricin transport from the endoplasmic reticulum to the cytosol.
S?omi?ska-Wojew?dzka M, Pawlik A, Soko?owska I, Antoniewicz J, W?grzyn G, Sandvig K
The Biochemical journal457(3)485-96(2014 Feb)
Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins.
Mast SW, Diekman K, Karaveg K, Davis A, Sifers RN, Moremen KW
Glycobiology15(4)421-36(2005 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Edem2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Edem2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10161 | |
Clone ID Related Accession (Same CDS sequence) | NM_001004230.1 | |
Accession Version | NM_001004230.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ER degradation-enhancing alpha-mannosidase-like protein 2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079029.1. On Sep 10, 2004 this sequence version replaced XM_215899.2. ##Evidence-Data-START## Transcript exon combination :: BC079029.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCCTTTCC GGCTGCTTAT CCCGCTCGGC CTCGTGTGCG TGCTGCTGCC CCTGCACCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001004230.1 |
CDS | 64..1794 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCCTTTCC GGCTGCTTAT CCCGCTCGGC CTCGTGTGCG TGCTGCTGCC CCTGCACCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step. |
The role of EDEM2 compared with EDEM1?in ricin transport from the endoplasmic reticulum to the cytosol. |
Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins. |